Citation Impact
Citing Papers
ShinyGO: a graphical gene-set enrichment tool for animals and plants
2019 Standout
Trapping of PARP1 and PARP2 by Clinical PARP Inhibitors
2012 Standout
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
RASTtk: A modular and extensible implementation of the RAST algorithm for building custom annotation pipelines and annotating batches of genomes
2015 Standout
Mms2–Ubc13 covalently bound to ubiquitin reveals the structural basis of linkage-specific polyubiquitin chain formation
2006
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Heatmapper: web-enabled heat mapping for all
2016 Standout
Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation
2007
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
2010 Standout
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis
2007 Standout
Regulation of chromatin by histone modifications
2011 Standout
DrugBank 3.0: a comprehensive resource for 'Omics' research on drugs
2010 Standout
TGFβ signalling in context
2012 Standout
Cancer drug resistance: an evolving paradigm
2013 Standout
ChEMBL: a large-scale bioactivity database for drug discovery
2011 Standout
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance
2012
DrugBank 4.0: shedding new light on drug metabolism
2013 Standout
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis
2012
Identification of BRCA1-IRIS, a BRCA1 locus product
2004
Multiplex assessment of protein variant abundance by massively parallel sequencing
2018
GeneSetDB: A comprehensive meta‐database, statistical and visualisation framework for gene set analysis
2012
Cell Cycle-dependent Complex Formation of BRCA1·CtIP·MRN Is Important for DNA Double-strand Break Repair
2008
BRCA1 and acetyl‐CoA carboxylase: The metabolic syndrome of breast cancer
2007
The Mdm2 RING domain C‐terminus is required for supramolecular assembly and ubiquitin ligase activity
2006
Maintenance of the DNA-Damage Checkpoint Requires DNA-Damage-Induced Mediator Protein Oligomerization
2009
Insights from the crystal structure of the sixth BRCT domain of topoisomerase IIβ binding protein 1
2009 StandoutNobel
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
Mitotic homologous recombination maintains genomic stability and suppresses tumorigenesis
2010
SMPDB 2.0: Big Improvements to the Small Molecule Pathway Database
2013
MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks
2005
The E2 Ubiquitin-conjugating Enzymes Direct Polyubiquitination to Preferred Lysines
2010
γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
2006
PubChem Substance and Compound databases
2015 Standout
The Structure of Fcp1, an Essential RNA Polymerase II CTD Phosphatase
2008
Mre11 Dimers Coordinate DNA End Bridging and Nuclease Processing in Double-Strand-Break Repair
2008
Metabolomics: beyond biomarkers and towards mechanisms
2016 Standout
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
Structural basis for phosphorylation-dependent signaling in the DNA-damage response
2005
The ConsensusPathDB interaction database: 2013 update
2012
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
2010
Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition
2016 StandoutNobel
Evaluation and comparison of bioinformatic tools for the enrichment analysis of metabolomics data
2018
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution
2007
Targeting DNA topoisomerase II in cancer chemotherapy
2009 Standout
MetaboAnalyst 3.0—making metabolomics more meaningful
2015 Standout
In-silico studies in Chinese herbal medicines’ research: Evaluation of in-silico methodologies and phytochemical data sources, and a review of research to date
2012
Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry
2011 Standout
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Genome editing with engineered zinc finger nucleases
2010 Standout
MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data
2010
Understanding eukaryotic linear motifs and their role in cell signaling and regulation
2008
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Fingerprinting food: current technologies for the detection of food adulteration and contamination
2012 Standout
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
2017 Standout
Supramolecular Coordination: Self-Assembly of Finite Two- and Three-Dimensional Ensembles
2011 Standout
Using MetaboAnalyst 3.0 for Comprehensive Metabolomics Data Analysis
2016 Standout
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
2013 Standout
A circadian gene expression atlas in mammals: Implications for biology and medicine
2014 Standout
Stabilization of mutant BRCA1 protein confers PARP inhibitor and platinum resistance
2013
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1
2012 Standout
RING Domain E3 Ubiquitin Ligases
2009 Standout
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway
2010 Standout
MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis
2018 Standout
Using MetaboAnalyst 4.0 for Comprehensive and Integrative Metabolomics Data Analysis
2019 Standout
The Ubiquitin-Proteasome Pathway and Its Role in Cancer
2005
The diverse biological roles of mammalian PARPS, a small but powerful family of poly-ADP-ribose polymerases
2007
Mre11–Rad50–Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin templateThis paper is one of a selection of papers published in this Special Issue, entitled 28th International West Coast Chromatin and Chromosome Conference, and has undergone the Journal's usual peer review process.
2007
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Olaparib Monotherapy in Patients With Advanced Cancer and a Germline BRCA1/2 Mutation
2014 Standout
The Ubiquitin Code
2012 Standout
The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
2020 Standout
Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics
2018 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Filamentous Phage Display in the New Millennium
2005
MetaboAnalyst 5.0: narrowing the gap between raw spectra and functional insights
2021 Standout
Works of David Hau being referenced
SMPDB: The Small Molecule Pathway Database
2009
Structural Basis for Non-Covalent Interaction Between Ubiquitin and the Ubiquitin Conjugating Enzyme Variant Human MMS2
2006
Detection of Protein Folding Defects Caused by BRCA1-BRCT Truncation and Missense Mutations
2003
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
2004
Learning to predict cancer-associated skeletal muscle wasting from 1H-NMR profiles of urinary metabolites
2010
Comprehensive Analysis of Missense Variations in the BRCT Domain of BRCA1 by Structural and Functional Assays
2010