Standout Papers

Guidelines for the welfare and use of animals in cancer research 2010 2026 2015 2020 1.1k
  1. Guidelines for the welfare and use of animals in cancer research (2010)
    Paul Workman, Eric O. Aboagye et al. British Journal of Cancer

Citation Impact

Citing Papers

Short-Chain Fatty Acids Stimulate Glucagon-Like Peptide-1 Secretion via the G-Protein–Coupled Receptor FFAR2
2011 Standout
Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930
2010
Trans , trans , trans -[PtIV(N3)2(OH)2(py)(NH3)]: A Light-Activated Antitumor Platinum Complex That Kills Human Cancer Cells by an Apoptosis-Independent Mechanism
2012
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Cyclin-Dependent Kinase Inhibitor AT7519 as a Potential Drug for MYCN-Dependent Neuroblastoma
2015
Zinc Finger Nucleases Targeting the Human Papillomavirus E7 Oncogene Induce E7 Disruption and a Transformed Phenotype in HPV16/18-Positive Cervical Cancer Cells
2014
Interleukin-6 as a Therapeutic Target in Human Ovarian Cancer
2011
Arid5a Promotes Immune Evasion by Augmenting Tryptophan Metabolism and Chemokine Expression
2021 StandoutNobel
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism
2013 Standout
Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint Blockade
2020
Rapid tumor induction in zebrafish by TALEN-mediated somatic inactivation of the retinoblastoma1 tumor suppressor rb1
2015
Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis
2015
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
2017 Standout
Ethoxyfagaronine, a synthetic analogue of fagaronine that inhibits vascular endothelial growth factor-1, as a new anti-angiogeneic agent
2014 StandoutNobel
Modeling the Adequacy of Dietary Fiber in Dairy Cows Based on the Responses of Ruminal pH and Milk Fat Production to Composition of the Diet
2008 Standout
Combinatorial drug therapy for cancer in the post-genomic era
2012
The Role of Short-Chain Fatty Acids in Health and Disease
2014 Standout
The role of gastrointestinal vagal afferents in the control of food intake: current prospects
2000
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research
2014 Standout
Expression of Cannabinoid CB1 Receptors by Vagal Afferent Neurons Is Inhibited by Cholecystokinin
2004
Regulation of adipokine production in human adipose tissue by propionic acid
2010
Anatomy and regulation of the central melanocortin system
2005 Standout
Review article: the role of butyrate on colonic function
2007 Standout
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
2009 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Descending control of pain
2002 Standout
The HIF-pathway inhibitor NSC-134754 induces metabolic changes and anti-tumour activity while maintaining vascular function
2012
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Biological actions of cholecystokinin
1994
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Cancer therapy monitoring in xenografts by quantitative analysis of circulating tumor DNA
2012
EMT Transition States during Tumor Progression and Metastasis
2018 Standout
Intestinal Protein Supply Alters Amino Acid, but Not Glucose, Metabolism by the Sheep Gastrointestinal Tract
2006
Hepatocellular carcinoma
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Amino acids: metabolism, functions, and nutrition
2009 Standout
Discovery of small molecule cancer drugs: Successes, challenges and opportunities
2012
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism
2016 Standout
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Antitumor activity of epigenetic immunomodulation combined with CTLA-4 blockade in syngeneic mouse models
2015
Effects of Diet on Short-Term Regulation of Feed Intake by Lactating Dairy Cattle
2000 Standout
Investigation of α-Synuclein Fibril Structure by Site-directed Spin Labeling
2007
The Endocannabinoid System as an Emerging Target of Pharmacotherapy
2006 Standout
Neuroendocrine and physiological regulation of intake with particular reference to domesticated ruminant animals
2008
Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms?
2014
Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms
2010
Biology of Dairy Cows During the Transition Period: the Final Frontier?
1999 Standout
Aspirin Inhibits mTOR Signaling, Activates AMP-Activated Protein Kinase, and Induces Autophagy in Colorectal Cancer Cells
2012
Effect of Long-Chain Fatty Acids on Triglyceride Accumulation, Gluconeogenesis, and Ureagenesis in Bovine Hepatocytes
1998
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
Development of a new epidermal growth factor receptor positron emission tomography imaging agent based on the 3-cyanoquinoline core: Synthesis and biological evaluation
2010
The Composition of Bovine Milk Lipids: January 1995 to December 2000
2002 Standout
The Role of Short-Chain Fatty Acids From Gut Microbiota in Gut-Brain Communication
2020 Standout
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
The role of short-chain fatty acids in microbiota–gut–brain communication
2019 Standout
Click Chemistry: 1,2,3‐Triazoles as Pharmacophores
2011 Standout
Perspectives on ruminant nutrition and metabolism. II. Metabolism in ruminant tissues
1999
Modeling and predicting clinical efficacy for drugs targeting the tumor milieu
2012
Invited review: Body condition score and its association with dairy cow productivity, health, and welfare
2009 Standout
Akt signalling in health and disease
2011 Standout
Short-chain fatty acids in control of body weight and insulin sensitivity
2015 Standout
Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade
2017 Standout
PGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
2022 StandoutNobel
Skepinone-L, a Novel Potent and Highly Selective Inhibitor of p38 MAP Kinase, Effectively Impairs Platelet Activation and Thrombus Formation
2013 Standout
Cancer-related inflammation and treatment effectiveness
2014 Standout
Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients
2017
Small Molecule Inhibitors of Aurora-A Induce Proteasomal Degradation of N-Myc in Childhood Neuroblastoma
2013
Propionate. Anti-obesity and satiety enhancing factor?
2011
Gut microbiota in human metabolic health and disease
2020 Standout
Butyrate reduces appetite and activates brown adipose tissue via the gut-brain neural circuit
2017
Cholecystokinin and leptin act synergistically to reduce body weight
2000
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Starch digestibility in food matrix: a review
2009 Standout
Introduction to the human gut microbiota
2017 Standout
Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.
2018 Standout
Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41
2004
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
2008 Standout
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Nutritional Significance of Lectins and Enzyme Inhibitors from Legumes
2002
Microbial degradation of complex carbohydrates in the gut
2012 Standout
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Combining TRAIL with PI3 Kinase or HSP90 inhibitors enhances apoptosis in colorectal cancer cells via suppression of survival signaling
2013
Chronic Inflammation and Cytokines in the Tumor Microenvironment
2014 Standout
Primary Human Non‐Small Cell Lung and Pancreatic Tumorgraft Models—Utility and Applications in Drug Discovery and Tumor Biology
2013
Proteomics analysis of the matrisome from MC38 experimental mouse liver metastases
2019
Anion Gap Toxicity in Alloxan Induced Type 2 Diabetic Rats Treated with Antidiabetic Noncytotoxic Bioactive Compounds of Ethanolic Extract ofMoringa oleifera
2014
De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute
2016 StandoutNobel
The G-protein-coupled receptor 40 family (GPR40–GPR43) and its role in nutrient sensing
2006
Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma
2014

Works of David Farningham being referenced

Guidelines for the welfare and use of animals in cancer research
2010 Standout
Effect of neonatal capsaicin treatment on cholecystokinin-(CCK8) satiety and axonal transport of CCK binding sites in the rat vagus nerve
1992
The role of propionate and acetate in the control of food intake in sheep
1993
Absorption of amino acids from the intestine and their net flux across the mesenteric- and portal-drained viscera of lambs.
1997
Hepatic detoxification of ammonia in the ovine liver: possible consequences for amino acid catabolism
1995
Satiety signals in sheep: Involvement of CCK, propionate, and vagal CCK binding sites
1993
Secretion of Pancreatic Digestive Enzymes Induced in Rats by First-Time Oral Exposure to Kidney Bean E2L2 Lectin Is Mediated Only in Part by Cholecystokinin (CCK)
1999
The selection of marmoset monkeys (Callithrix jacchus) in pharmaceutical toxicology
2001
Rankless by CCL
2026