Citation Impact
Citing Papers
Myosin V Walks Hand-Over-Hand: Single Fluorophore Imaging with 1.5-nm Localization
2003 Science
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
2007 StandoutScienceNobel
Atomic-Level Characterization of the Structural Dynamics of Proteins
2010 StandoutScienceNobel
Imaging Intracellular Fluorescent Proteins at Nanometer Resolution
2006 StandoutScienceNobel
Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor
2000 StandoutScience
Computational design of soluble and functional membrane protein analogues
2024 StandoutNatureNobel
Single myosin molecule mechanics: piconewton forces and nanometre steps
1994 Nature
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
From molecular to modular cell biology
1999 StandoutNatureNobel
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Projection structure of rhodopsin
1993 StandoutNatureNobel
Sliding distance between actin and myosin filaments per ATP molecule hydrolysed in skinned muscle fibres
1991 Nature
The myosin swinging cross-bridge model
2001
Crystal structure of the human β2 adrenergic G-protein-coupled receptor
2007 StandoutNatureNobel
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Unidirectional molecular motor on a gold surface
2005 StandoutNatureNobel
Light-driven monodirectional molecular rotor
1999 StandoutNatureNobel
Dobutamine stress Doppler hemodynamics in patients with aortic stenosis: Feasibility, safety, and surgical correlations
1998
Synthetic Molecular Motors and Mechanical Machines
2006 Standout
Unscrambling the puzzle of biological machines: The importance of the details
1992
Hemodynamic stability of valve area, valve resistance, and stroke work loss in aortic stenosis: A comparative analysis
2002
A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes
2008
CHRONIC AORTIC REGURGITATION
1998
Chronic Aortic Regurgitation: Indications for Operation—1988
1988
Imaging of single fluorescent molecules and individual ATP turnovers by single myosin molecules in aqueous solution
1995 Nature
Quantized velocities at low myosin densities in an in vitro motility
1991 Nature
Structure and function of an irreversible agonist-β2 adrenoceptor complex
2011 StandoutNatureNobel
Usefulness of dobutamine echocardiography in distinguishing severe from nonsevere valvular aortic stenosis in patients with depressed left ventricular function and low transvalvular gradients
1995
Rhodopsin structure, dynamics, and activation: A perspective from crystallography, site-directed spin labeling, sulfhydryl reactivity, and disulfide cross-linking
2003
Direct observation of single kinesin molecules moving along microtubules
1996 Nature
Identification and sequence of a binding site peptide of the .beta.2-adrenergic receptor
1988
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor
2010 StandoutNatureNobel
Long-Term Vasodilator Therapy in Patients with Severe Aortic Regurgitation
2005
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
On/off blinking and switching behaviour of single molecules of green fluorescent protein
1997 StandoutNatureNobel
De novo design of a pentameric coiled‐coil: decoding the motif for tetramer versus pentamer formation in water‐soluble phospholamban*
2005
The coming of age of de novo protein design
2016 StandoutNatureNobel
Biophysical and genetic analysis of the ligand-binding site of the β-adrenoceptor
1991
Comparison of single-dose nifedipine and captopril for chronic severe aortic regurgitation
1993
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
[18] Fluorescence resonance energy transfer and nucleic acids
1992
The structure and function of G-protein-coupled receptors
2009 StandoutNatureNobel
Sub-piconewton force fluctuations of actomyosin in vitro
1991 Nature
Site-Specific Fluorescence Labeling of the β2Adrenergic Receptor Amino Terminus
1997 StandoutNobel
Electrically driven directional motion of a four-wheeled molecule on a metal surface
2011 StandoutNatureNobel
Testing time for muscle
1992
Nifedipine in Asymptomatic Patients with Severe Aortic Regurgitation and Normal Left Ventricular Function
1994
Tryptophan 512 Is Sensitive to Conformational Changes in the Rigid Relay Loop of Smooth Muscle Myosin during the MgATPase Cycle
2000
The superfamily of heptahelical receptors
2000 StandoutNobel
Structure of a nanobody-stabilized active state of the β2 adrenoceptor
2011 StandoutNatureNobel
Direct observation of the rotation of F1-ATPase
1997 StandoutNature
Imaging protein molecules using FRET and FLIM microscopy
2004
Conformational control of DNA target cleavage by CRISPR–Cas9
2015 StandoutNatureNobel
Clinical outcome of severe asymptomatic chronic aortic regurgitation: A long-term prospective follow-up study
1995
Dobutamine Echocardiography in Patients With Aortic Stenosis and Left Ventricular Dysfunction
2001
Managing Asymptomatic Patients With Chronic Aortic Regurgitation
1997
Effects of dobutamine on doppler echocardiographic indexes of aortic stenosis
1996
Fluorescence ratio imaging of cyclic AMP in single cells
1991 StandoutNatureNobel
Hemodynamic progression of aortic stenosis in adults assessed by doppler echocardiography
1989
The binding change mechanism for ATP synthase — Some probabilities and possibilities
1993 StandoutNobel
Removal of phosphorylation sites from the β2-adrenergic receptor delays onset of agonist-promoted desensitization
1988 StandoutNatureNobel
Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating
2002
Synthesizing life
2001 StandoutNatureNobel
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
1988 StandoutNatureNobel
Why ion pair reversal by protein engineering is unlikely to succeed
1988 StandoutNatureNobel
Structure of a β1-adrenergic G-protein-coupled receptor
2008 StandoutNatureNobel
Vasodilation with felodipine in chronic asymptomatic aortic regurgitation
2000
Long-term nifedipine unloading therapy in asymptomatic patients with chronic severe aortic regurgitation
1990
Vasodilator therapy in chronic asymptomatic aortic regurgitation: Enalapril versus hydralazine therapy
1994
Aortic regurgitation complicated by extreme left ventricular dilation: Long-term outcome after surgical correction
1996
Vasoactive drugs in chronic regurgitant lesions of the mitral and aortic valves
1996
Chronic Aortic Insufficiency: Factors Associated with Progression to Aortic Valve Replacement
1989
Dynamics of the Upper 50-kDa Domain of Myosin V Examined with Fluorescence Resonance Energy Transfer
2005 StandoutNobel
The transmembrane 7-alpha-bundle of rhodopsin: distance geometry calculations with hydrogen bonding constraints
1997
Structure at 2.8 Â resolution of F1-ATPase from bovine heart mitochondria
1994 StandoutNatureNobel
Myosin step size: Estimates from motility assays and shortening muscle
1992
Direct observation of kinesin stepping by optical trapping interferometry
1993 StandoutNature
Molecular Characterization of a Functional cDNA Encoding the Serotonin 1c Receptor
1988 StandoutScienceNobel
Imaging and Time-Resolved Spectroscopy of Single Molecules at an Interface
1996 StandoutScienceNobel
Rhodopsin and bacteriorhodopsin: structure—function relationships
1982
Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain
2014
Evidence that the Head of Kinesin Is Sufficient for Force Generation and Motility in Vitro
1990 Science
Regulation of Receptor Fate by Ubiquitination of Activated β 2 -Adrenergic Receptor and β-Arrestin
2001 StandoutScienceNobel
OPTICAL DETECTION OF SINGLE MOLECULES
1997
Active multi-subunit ACh receptor assembled by translation of heterologous mRNA in Xenopus oocytes
1981 StandoutNatureNobel
Chimeric α 2 -,β 2 -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity
1988 StandoutScienceNobel
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins
1987 StandoutNatureNobel
Primary Structure and Biochemical Properties of an M 2 Muscarinic Receptor
1987 Science
The opsin family of proteins
1986
Kinetic Characterization of the Weak Binding States of Myosin V
2002
Prediction of Indications for Valve Replacement Among Asymptomatic or Minimally Symptomatic Patients With Chronic Aortic Regurgitation and Normal Left Ventricular Performance
1998
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
2006 Standout
The probable arrangement of the helices in G protein-coupled receptors.
1993
The Mechanism of Muscle Contractio
1986
Resonance energy transfer microscopy: observations of membrane-bound fluorescent probes in model membranes and in living cells.
1986
Low-Gradient Aortic Stenosis
2003
Task force 2: Acquired valvular heart disease
1994
Theoretical studies of enzymic reactions: Dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme
1976 StandoutNobel
Conversion of Phospholamban into a Soluble Pentameric Helical Bundle
2001 StandoutNobel
Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain.
1988
Prospective Study of Asymptomatic Valvular Aortic Stenosis
1997
Stretching of a Single Tethered Polymer in a Uniform Flow
1995 StandoutScienceNobel
Illuminating Single Molecules in Condensed Matter
1999 StandoutScienceNobel
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase
1986 StandoutNatureNobel
Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α 2 -Adrenergic Receptor
1987 StandoutScienceNobel
Studies on the mechanism of membrane fusion: kinetics of calcium ion induced fusion of phosphatidylserine vesicles followed by a new assay for mixing of aqueous vesicle contents
1980
Seven-helix receptors
1991
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Coupling between phosphate release and force generation in muscle actomyosin
2004
Ligand binding to the β-adrenergic receptor involves its rhodopsin-like core
1987 Nature
Cyclic GMP Cascade of Vision
1986
Calculations of electrostatic interactions in biological systems and in solutions
1984 StandoutNobel
Characterization of the binding domain of the beta-adrenergic receptor with the fluorescent antagonist carazolol. Evidence for a buried ligand binding site.
1990
Structural and Functional Properties of the Acetylcholine Receptor Protein in its Purified and Membrane-Bound States
1978
The Effect of F-Actin on the Relay Helix Position of Myosin II, as Revealed by Tryptophan Fluorescence, and Its Implications for Mechanochemical Coupling
2004
Works of David D. Thomas being referenced
NMR Solution Structure and Topological Orientation of Monomeric Phospholamban in Dodecylphosphocholine Micelles
2003
Left ventricular response to submaximal and maximal exercise in asymptomatic aortic regurgitation
1988
Effects of Membrane Thickness on the Molecular Dynamics and Enzymic Activity of Reconstituted Ca-ATPase
1994
Effects of AMPPNP on the orientation and rotational dynamics of spin-labeled muscle cross-bridges
1988
Sarcolipin, the Shorter Homologue of Phospholamban, Forms Oligomeric Structures in Detergent Micelles and in Liposomes
2001
A Fluorescence Energy Transfer Method for Analyzing Protein Oligomeric Structure: Application to Phospholamban
1999
Resolution of three structural states of spin-labeled myosin in contracting muscle
1995
Mechanochemical coupling in actomyosin energy transduction studied by in vitro movement assay
1990
Rotational dynamics of actin-bound myosin heads in active myofibrils
1993
Structural Mapping of Divergent Regions in the Type 1 Ryanodine Receptor Using Fluorescence Resonance Energy Transfer
2014
Rotational dynamics of actin-bound intermediates in the myosin ATPase cycle
1991
Phosphorylation-Induced Structural Change in Phospholamban and Its Mutants, Detected by Intrinsic Fluorescence
1998
Rotational diffusion studied by passage saturation transfer electron paramagnetic resonance
1976
Conformational transitions in the calcium adenosine triphosphatase studied by time-resolved fluorescence resonance energy transfer
1989
Photolysis of a photolabile precursor of ATP (caged ATP) induces microsecond ratational motions of myosin heads bound to actin.
1989
Muscle Cross-Bridges: Do They Rotate?
1984
Long-term vasodilator therapy of chronic aortic insufficiency. A randomized double-blinded, placebo-controlled clinical trial.
1988
Motion of subfragment-1 in myosin and its supramolecular complexes: saturation transfer electron paramagnetic resonance.
1975
Intertest variability of echocardiographic and chest X-Ray measurements: Implications for dDecision making in patients with aortic regurgitation
1986
Submillisecond rotational dynamics of spin-labeled myosin heads in myofibrils
1980
Association between the exercise ejection fraction response and systolic wall stress in patients with chronic aortic insufficiency.
1985
[90] Fluorescence energy transfer measurements of distances in rhodopsin and the purple membrane protein
1982
Cysteine Reactivity and Oligomeric Structures of Phospholamban and Its Mutants
1998
Diffusion-Enhanced Fluorescence Energy Transfer
1982
Saturation transfer electron paramagnetic resonance of spin-labeled muscle fibers
1984
Direct Detection of Phospholamban and Sarcoplasmic Reticulum Ca-ATPase Interaction in Membranes Using Fluorescence Resonance Energy Transfer
2004
Orientation of spin-labeled myosin heads in glycerinated muscle fibers
1980
Reproducibility of rest and exercise left ventricular ejection fraction and volumes in chronic aortic regurgitation
1987
A large and distinct rotation of the myosin light chain domain occurs upon muscle contraction
1998
Molecular orbital calculations of the catalytic effect of lysozyme
1972
Transverse location of the retinal chromophore of rhodopsin in rod outer segment disc membranes
1982
Fluorescence energy transfer in the rapid-diffusion limit
1978
Orientation and rotational mobility of spin-labelled myosin heads in insect flight muscle in rigor
1983
Spectroscopic Probes of Muscle Cross-Bridge Rotation
1987
Phospholamban Pentamer Quaternary Conformation Determined by In-Gel Fluorescence Anisotropy,
2005
Saturation transfer electron paramagnetic resonance on membrane-bound proteins. I-rotational diffusion of rhodopsin in the visual receptor membrane
1977
Structural Dynamics of Actin during Active Interaction with Myosin: Different Effects of Weakly and Strongly Bound Myosin Heads
2004
Dependence of Gorlin formula and continuity equation valve areas on transvalvular volume flow rate in valvular aortic stenosis.
1994
Microsecond rotational motions of eosin-labeled myosin measured by time-resolved anisotropy of absorption and phosphorescence
1984
The mechanism of force generation in myosin: a disorder-to-order transition, coupled to internal structural changes.
1995
The quantitative measurement of rotational motion of the subfragment‐1 region of myosin by saturation transfer EPR spectroscopy
1975
Myosin heads have a broad orientational distribution during isometric muscle contraction: time-resolved EPR studies using caged ATP.
1990
Rotational dynamics of spin-labeled F-actin in the sub-millisecond time range
1979
Orientation of spin labels attached to cross-bridges in contracting muscle fibres
1982 Nature