Citation Impact
Citing Papers
Activating Mutations in PIK3CB Confer Resistance to PI3K Inhibition and Define a Novel Oncogenic Role for p110β
2016
Long-term treatment of epilepsy with everolimus in tuberous sclerosis
2016
Alpelisib for PIK3CA -Mutated, Hormone Receptor–Positive Advanced Breast Cancer
2019 Standout
A Phase I Study of the AKT Inhibitor MK-2206 in Combination with Hormonal Therapy in Postmenopausal Women with Estrogen Receptor–Positive Metastatic Breast Cancer
2016
The Genetic Landscape and Clonal Evolution of Breast Cancer Resistance to Palbociclib plus Fulvestrant in the PALOMA-3 Trial
2018
Rituximab chimeric anti-CD20 monoclonal antibody therapy for relapsed indolent lymphoma: half of patients respond to a four-dose treatment program.
1998 Standout
Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial
2016 Standout
Breast cancer
2019 Standout
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
2019 StandoutNobel
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Estrogen receptor mutations and their role in breast cancer progression
2014
Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer
2015
Gastric cancer
2016 Standout
Astrocytes: biology and pathology
2009 Standout
PIK3CA mutations in breast cancer: reconciling findings from preclinical and clinical data
2014
NF-κB-Activating Complex Engaged in Response to EGFR Oncogene Inhibition Drives Tumor Cell Survival and Residual Disease in Lung Cancer
2015
A view on drug resistance in cancer
2019 StandoutNature
Breast cancer
2016 Standout
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research
2014 Standout
Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): a double-blind, randomised phase 3 trial
2014 Standout
Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS
2008
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Consensus statement on abusive head trauma in infants and young children
2018
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Whole-Exome Sequencing in Two Extreme Phenotypes of Response to VEGF-Targeted Therapies in Patients With Metastatic Clear Cell Renal Cell Carcinoma
2016
Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis
2016
Predicting treatment resistance and relapse through circulating DNA
2017
Hereditary Kidney Cancer Syndromes
2013
Stem Cell Therapies in Clinical Trials: Progress and Challenges
2015 Standout
The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program “CASCADE”
2016
Tumorigenesis: it takes a village
2015
Hallmarks of aging: An expanding universe
2023 Standout
ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
2006
Rapamycin: One Drug, Many Effects
2014 Standout
Topical Use of Mammalian Target of Rapamycin (mTOR) Inhibitors in Tuberous Sclerosis Complex—A Comprehensive Review of the Literature
2016
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Advances in the treatment of advanced oestrogen-receptor-positive breast cancer
2016
Liquid Biopsies, What We Do Not Know (Yet)
2017
Hepatocellular carcinoma
2021 Standout
Extensive Neuronal Differentiation of Human Neural Stem Cell Grafts in Adult Rat Spinal Cord
2007
Focal transplantation–based astrocyte replacement is neuroprotective in a model of motor neuron disease
2008
Current and future perspectives of liquid biopsies in genomics-driven oncology
2018 Standout
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
The past, present and future of stem cell clinical trials for ALS
2014
Clinical value of circulating <em>ESR1</em> mutations for patients with metastatic breast cancer: a meta-analysis
2018
Everolimus for subependymal giant cell astrocytoma in patients with tuberous sclerosis complex: 2-year open-label extension of the randomised EXIST-1 study
2014
Randomized trials and endpoints in advanced HCC: Role of PFS as a surrogate of survival
2019
Implementing Genome-Driven Oncology
2017
Bladder cancer
2016 Standout
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
mTOR treatment in lymphangioleiomyomatosis: the role of everolimus
2016
Treatment for the endocrine resistant breast cancer: Current options and future perspectives
2017
Emerging Biological Principles of Metastasis
2017 Standout
Overcome tumor heterogeneity-imposed therapeutic barriers through convergent genomic biomarker discovery: A braided cancer river model of kidney cancer
2016
The quest to slow ageing through drug discovery
2020
Correlation Between Molecular Subclassifications of Clear Cell Renal Cell Carcinoma and Targeted Therapy Response
2015
Coronary Calcium as a Predictor of Coronary Events in Four Racial or Ethnic Groups
2008 Standout
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor-2-negative advanced breast cancer: overall survival results from BOLERO-2
2014
Palbociclib and Letrozole in Advanced Breast Cancer
2016 Standout
The PI3K Pathway in Human Disease
2017 Standout
The Evaluation of Suspected Child Physical Abuse
2015 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Renal cell carcinoma
2017 Standout
Protein therapeutics: a summary and pharmacological classification
2007 Standout
Tumour heterogeneity and resistance to cancer therapies
2017 Standout
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
CHILDREN OR YOUNG ADULTS? A POPULATION‐BASED STUDY ON ADOLESCENT HEAD INJURY
2006
Hepatocellular carcinoma
2022 Standout
Tuberous sclerosis complex: From molecular biology to novel therapeutic approaches
2016
Annual Risk of Death Resulting From Short Falls Among Young Children: Less Than 1 in 1 Million
2008
Estimating the global incidence of traumatic brain injury
2018 Standout
Efficacy and Safety of Topical Sirolimus Therapy for Facial Angiofibromas in the Tuberous Sclerosis Complex
2016
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
Depletion of B cells in vivo by a chimeric mouse human monoclonal antibody to CD20
1994 Standout
Offline assessment of atherosclerotic coronary calcium from electron beam tomograms.
1995
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
2016 StandoutNobel
Radioimmunotherapy with iodine 131I tositumomab for relapsed or refractory B-cell non-Hodgkin lymphoma: updated results and long-term follow-up of the University of Michigan experience
2000
Chemotherapy for advanced gastric cancer
2017 Standout
Breast Cancer Treatment
2019 Standout
A Phase Ib Study of Alpelisib (BYL719), a PI3Kα-Specific Inhibitor, with Letrozole in ER+/HER2− Metastatic Breast Cancer
2016
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Plasma ESR1 Mutations and the Treatment of Estrogen Receptor–Positive Advanced Breast Cancer
2016
Monoclonal antibody-based therapies of leukemia and lymphoma
1992
Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer
2015
Neoadjuvant Dose-Dense Methotrexate, Vinblastine, Doxorubicin, and Cisplatin With Pegfilgrastim Support in Muscle-Invasive Urothelial Cancer: Pathologic, Radiologic, and Biomarker Correlates
2014
Everolimus for Previously Treated Advanced Gastric Cancer: Results of the Randomized, Double-Blind, Phase III GRANITE-1 Study
2013
Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex
2014
Constraints in cancer evolution
2017
Grafted human-induced pluripotent stem-cell–derived neurospheres promote motor functional recovery after spinal cord injury in mice
2011 StandoutNobel
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer
2015
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Phase III Trial Evaluating Letrozole As First-Line Endocrine Therapy With or Without Bevacizumab for the Treatment of Postmenopausal Women With Hormone Receptor–Positive Advanced-Stage Breast Cancer: CALGB 40503 (Alliance)
2016
Works of David Chen being referenced
Loss of Tuberous Sclerosis Complex 2 (TSC2) Is Frequent in Hepatocellular Carcinoma and Predicts Response to mTORC1 Inhibitor Everolimus
2015
Circulating biomarkers and outcome from a randomised phase II trial of sunitinib vs everolimus for patients with metastatic renal cell carcinoma
2016
A Phase I Escalating-Dose Safety, Dosimetry and Efficacy Study of Radiolabeled Monoclonal Antibody LYM-1
1993
Integrative biomarker analyses indicate etiological variations in hepatocellular carcinoma
2016
Everolimus for angiomyolipoma associated with tuberous sclerosis complex or sporadic lymphangioleiomyomatosis (EXIST-2): a multicentre, randomised, double-blind, placebo-controlled trial
2013
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
2013
Correlation of molecular alterations with efficacy of everolimus in hormone receptor–positive, HER2-negative advanced breast cancer: Results from BOLERO-2.
2013
Combined Immunosuppressive Agents or CD4 Antibodies Prolong Survival of Human Neural Stem Cell Grafts and Improve Disease Outcomes in Amyotrophic Lateral Sclerosis Transgenic Mice
2006
Identification of efficacy biomarkers in a large metastatic renal cell carcinoma (mRCC) cohort through next generation sequencing (NGS): Results from RECORD-3.
2015
Neoadjuvant accelerated MVAC (AMVAC) in patients with muscle invasive bladder cancer: Results of a multicenter phase II study.
2012
Pediatric Falls: Is Height a Predictor of Injury and Outcome?
2000
Correlation of molecular alterations with efficacy of everolimus in hormone-receptor–positive (HR+), HER2-negative advanced breast cancer: Preliminary results from BOLERO-2.
2013
Prevalence of ESR1 Mutations in Cell-Free DNA and Outcomes in Metastatic Breast Cancer
2016
Mechanistically distinct cancer-associated mTOR activation clusters predict sensitivity to rapamycin
2016
Randomized Phase II Study of Erlotinib in Combination With Placebo or R1507, a Monoclonal Antibody to Insulin-Like Growth Factor-1 Receptor, for Advanced-Stage Non–Small-Cell Lung Cancer
2011