Standout Papers
Citation Impact
Citing Papers
Computer‐Assisted Synthetic Planning: The End of the Beginning
2016
Direct and Catalytic C ‐Glycosylation of Arenes: Expeditious Synthesis of the Remdesivir Nucleoside**
2021 StandoutNobel
Developments in Direct CH Arylation of (Hetero)Arenes under Microwave Irradiation
2013
Flow Metal‐Free ArC Bond Formation via Photogenerated Phenyl Cations
2016
Catalytic Functionalization of C(sp2)H and C(sp3)H Bonds by Using Bidentate Directing Groups
2013 Standout
Chemoenzymatic Fc Glycosylation via Engineered Aldehyde Tags
2014 StandoutNobel
Extremely Fast Gas/Liquid Reactions in Flow Microreactors: Carboxylation of Short‐Lived Organolithiums
2014
Highly Selective Continuous‐Flow Synthesis of Potentially Bioactive Deuterated Chalcone Derivatives
2015
Tandem CH Activation/Arylation Catalyzed by Low‐Valent Iron Complexes with Bisiminopyridine Ligands
2014
Continuous Flow Synthesis of Ketones from Carbon Dioxide and Organolithium or Grignard Reagents
2014
Continuous‐Flow Synthesis of Functionalized Phenols by Aerobic Oxidation of Grignard Reagents
2014
Machine learning for molecular and materials science
2018 StandoutNature
An autonomous organic reaction search engine for chemical reactivity
2017
Accessing New Chemical Entities through Microfluidic Systems
2014
The synthesis of active pharmaceutical ingredients (APIs) using continuous flow chemistry
2015
Microwave Effects in Organic Synthesis: Myth or Reality?
2012
Multistage extraction platform for highly efficient and fully continuous purification of nanoparticles
2017 StandoutNobel
Engineering an efficient and enantioselective enzyme for the Morita–Baylis–Hillman reaction
2021 StandoutNobel
Organocatalytic umpolung: N-heterocyclic carbenes and beyond
2012 Standout
Nanocatalysis in Flow
2015
Iron catalysed direct alkylation of amines with alcohols
2014 StandoutNobel
Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds
2011
The Microwave‐to‐Flow Paradigm: Translating High‐Temperature Batch Microwave Chemistry to Scalable Continuous‐Flow Processes
2011
Flash generation of α-(trifluoromethyl)vinyllithium and application to continuous flow three-component synthesis of α-trifluoromethylamides
2014
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
Batch versus Flow Photochemistry: A Revealing Comparison of Yield and Productivity
2014
Reactions of Difunctional Electrophiles with Functionalized Aryllithium Compounds: Remarkable Chemoselectivity by Flash Chemistry
2014
Photochemical Transformations Accelerated in Continuous‐Flow Reactors: Basic Concepts and Applications
2014
Continuous Flow Reduction of Artemisinic Acid Utilizing Multi‐Injection Strategies—Closing the Gap Towards a Fully Continuous Synthesis of Antimalarial Drugs
2015
Immobilized Iron Oxide Nanoparticles as Stable and Reusable Catalysts for Hydrazine‐Mediated Nitro Reductions in Continuous Flow
2014
Frustrated Lewis Pair Chemistry: Development and Perspectives
2015 Standout
Beyond Directing Groups: Transition‐Metal‐Catalyzed CH Activation of Simple Arenes
2012 Standout
Applications of Continuous-Flow Photochemistry in Organic Synthesis, Material Science, and Water Treatment
2016
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
A review on fundamentals for designing oxygen evolution electrocatalysts
2020 Standout
Liquid Organic Hydrogen Carriers (LOHCs): Toward a Hydrogen-free Hydrogen Economy
2016 Standout
Iron Catalysis in Organic Synthesis
2015 Standout
Toward the Synthesis of Noroxymorphone via Aerobic Palladium-Catalyzed Continuous Flow N-Demethylation Strategies
2016
3d Transition Metals for C–H Activation
2018 Standout
SuFEx Click Chemistry Enabled Late-Stage Drug Functionalization
2018 StandoutNobel
The Golden Age of Transfer Hydrogenation
2015 Standout
Continuous‐Flow Synthesis of Biaryls by Negishi Cross‐Coupling of Fluoro‐ and Trifluoromethyl‐Substituted (Hetero)arenes
2016
Three-Component Coupling Based on Flash Chemistry. Carbolithiation of Benzyne with Functionalized Aryllithiums Followed by Reactions with Electrophiles
2014
Highly selective transfer hydrogenation of functionalised nitroarenes using cobalt-based nanocatalysts
2014
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Heterogeneously Catalyzed Alcohol Oxidation for the Fine Chemical Industry
2015
Computational Mechanistic Study of PMe3 and N-Heterocyclic Carbene Catalyzed Intramolecular Morita−Baylis−Hillman-Like Cycloalkylations: The Origins of the Different Reactivity
2011
Bifunctional Molecular Photoswitches Based on Overcrowded Alkenes for Dynamic Control of Catalytic Activity in Michael Addition Reactions
2016 StandoutNobel
Flow Update for a Cossy Photocyclization
2016
Intramolecular Direct C–H Bond Arylation from Aryl Chlorides: A Transition-Metal-Free Approach for Facile Access of Phenanthridines
2012
Metal–Organic Framework Mediated Cobalt/Nitrogen‐Doped Carbon Hybrids as Efficient and Chemoselective Catalysts for the Hydrogenation of Nitroarenes
2017
Palladium on Carbon-Catalyzed Suzuki-Miyaura Coupling Reaction Using an Efficient and Continuous Flow System
2015
Using weak interactions to control C–H mono-nitration of indolines
2017
Use of Bromine and Bromo-Organic Compounds in Organic Synthesis
2016
Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications
2019 Standout
Integration of borylation of aryllithiums and Suzuki–Miyaura coupling using monolithic Pd catalyst
2016
Flash carboxylation: fast lithiation–carboxylation sequence at room temperature in continuous flow
2014
Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes
2015
Selective Olefin Reduction in Thebaine Using Hydrazine Hydrate and O2 under Intensified Continuous Flow Conditions
2015
Flow chemistry as a versatile tool for the synthesis of triazoles
2015
Organic Photoredox Catalysis
2016 Standout
Use of a “Catalytic” Cosolvent, N,N‐Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch
2016
The accelerated preparation of 1,4-dihydropyridines using microflow reactors
2014
The Use of Molecular Oxygen in Pharmaceutical Manufacturing: Is Flow the Way to Go?
2016
Phosphine-catalyzed addition of P(O)–H compounds to ethyl phenylpropiolate
2015
A Method for the Selective Hydrogenation of Alkenyl Halides to Alkyl Halides
2014
Exploring the reactivity of a ruthenium complex in the metathesis of biorenewable feedstocks to generate value-added chemicals
2015
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
One-Pot Synthesis of α-Haloketones Employing a Membrane-Based Semibatch Diazomethane Generator
2016
Multicomponent Click Synthesis of 1,2,3-Triazoles from Epoxides in Water Catalyzed by Copper Nanoparticles on Activated Carbon
2011
Synthetic applications of eosin Y in photoredox catalysis
2014
Chemicals from lignin: an interplay of lignocellulose fractionation, depolymerisation, and upgrading
2018 Standout
Controlled generation and use of CO in flow
2016
State of the Art and Prospects in Metal–Organic Framework (MOF)-Based and MOF-Derived Nanocatalysis
2019 Standout
The Hitchhiker’s Guide to Flow Chemistry
2017 Standout
Ultrafine palladium nanoparticles immobilized into poly(4-vinylpyridine)-based porous monolith for continuous-flow Mizoroki–Heck reaction
2016
A greener process for flow C–H chlorination of cyclic alkanes using in situ generation and on-site consumption of chlorine gas
2016
Mild metal-catalyzed C–H activation: examples and concepts
2016 Standout
Manganese(I)‐Catalyzed C−H (2‐Indolyl)methylation: Expedient Access to Diheteroarylmethanes
2017
Why Does Industry Not Use Immobilized Transition Metal Complexes as Catalysts?
2015
Multi-step continuous-flow synthesis
2017
Covalent Organic Frameworks: Design, Synthesis, and Functions
2020 Standout
Discovery and mechanistic study of a photocatalytic indoline dehydrogenation for the synthesis of elbasvir
2015
Continuous-Flow Electrophilic Amination of Arenes and Schmidt Reaction of Carboxylic Acids Utilizing the Superacidic Trimethylsilyl Azide/Triflic Acid Reagent System
2016
From alcohol to 1,2,3-triazole via a multi-step continuous-flow synthesis of a rufinamide precursor
2016
Phosphine Organocatalysis
2018 Standout
Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis
2014
Photochemical Fluorination Reactions – A Promising Research Field for Continuous‐Flow Synthesis
2015
Rapid Asymmetric Synthesis of Disubstituted Allenes by Coupling of Flow‐Generated Diazo Compounds and Propargylated Amines
2017
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Process Intensified Flow Synthesis of 1H-4-Substituted Imidazoles: Toward the Continuous Production of Daclatasvir
2015
Continuous, Fast, and Safe Aerobic Oxidation of 2-Ethylhexanal: Pushing the Limits of the Simple Tube Reactor for a Gas/Liquid Reaction
2015
Microwave-assisted amination from fluorobenzenes without catalyst and strong base
2012
Synthesis of Biaryls through Aromatic CH Bond Activation: A Review of Recent Developments
2014
Applications of Acceptorless Dehydrogenation and Related Transformations in Chemical Synthesis
2013 StandoutScience
Development of a Large-Scale Cyanation Process Using Continuous Flow Chemistry En Route to the Synthesis of Remdesivir
2020
Supported Catalysis in Continuous‐Flow Microreactors
2015
On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system
2016 Science
Switching between intermolecular and intramolecular reactions using flow microreactors: lithiation of 2-bromo-2′-silylbiphenyls
2016
The medicinal chemist's toolbox for late stage functionalization of drug-like molecules
2015
Fast-Growing Field of Magnetically Recyclable Nanocatalysts
2014
A Sequential Ugi Multicomponent/Cu-Catalyzed Azide–Alkyne Cycloaddition Approach for the Continuous Flow Generation of Cyclic Peptoids
2015
Synthesis of axially chiral biaryl compounds by asymmetric catalytic reactions with transition metals
2015
Quantum chemical investigation on the reaction mechanism of tertiary phosphines with unsaturated carboxylic acids: An insight into kinetic data
2012
Recent Advances in Organocatalytic Asymmetric Morita–Baylis–Hillman/aza-Morita–Baylis–Hillman Reactions
2013
Continuous Visible‐Light Photoflow Approach for a Manganese‐Catalyzed (Het)Arene C−H Arylation
2018
Azine Activation via Silylium Catalysis
2021 StandoutNobel
A scalable and safe continuous flow procedure for in-line generation of diazomethane and its precursor MNU
2016
Liquid phase oxidation chemistry in continuous-flow microreactors
2015
Benzyllithiums bearing aldehyde carbonyl groups. A flash chemistry approach
2015
PTFE-Membrane Flow Reactor for Aerobic Oxidation Reactions and Its Application to Alcohol Oxidation
2015
A Simple Scale-up Strategy for Organolithium Chemistry in Flow Mode: From Feasibility to Kilogram Quantities
2016
Continuous‐Flow Multistep Synthesis of Cinnarizine, Cyclizine, and a Buclizine Derivative from Bulk Alcohols
2015
Green and Sustainable Solvents in Chemical Processes
2018 Standout
Flow “Fine” Synthesis: High Yielding and Selective Organic Synthesis by Flow Methods
2015
Epoxidation using molecular oxygen in flow: facts and questions on the mechanism of the Mukaiyama epoxidation
2016
Challenges in the Greener Production of Formates/Formic Acid, Methanol, and DME by Heterogeneously Catalyzed CO2Hydrogenation Processes
2017 Standout
The Rise of Magnetically Recyclable Nanocatalysts
2014
Application of Continuous Flow for DIBAL-H Reduction and n-BuLi Mediated Coupling Reaction in the Synthesis of Eribulin Mesylate
2015
Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products
2015
Reduction of Nitro Compounds Using 3d-Non-Noble Metal Catalysts
2018
Mechanism and Scope of Base‐Controlled Catalyst‐Free N‐Arylation of Amines with Unactivated Fluorobenzenes
2016 StandoutNobel
Optimizing the Heck–Matsuda Reaction in Flow with a Constraint-Adapted Direct Search Algorithm
2016
Synthesis of ketones via organolithium addition to acid chlorides using continuous flow chemistry
2015
Continuous Flow Homolytic Aromatic Substitution with Electrophilic Radicals: A Fast and Scalable Protocol for Trifluoromethylation
2016
Flow fine synthesis with heterogeneous catalysts
2018
A Small-Footprint, High-Capacity Flow Reactor for UV Photochemical Synthesis on the Kilogram Scale
2016
Dendrimer-encapsulated Pd nanoparticles as catalysts for C–C cross-couplings in flow microreactors
2015
Metal‐Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous‐Flow
2015
Dual Catalysis Strategies in Photochemical Synthesis
2016 Standout
Rapid production of benzazole derivatives by a high-pressure and high-temperature water microflow chemical process
2016
Taming hazardous chemistry by continuous flow technology
2016
Ohne dirigierende Gruppen: übergangsmetallkatalysierte C‐H‐Aktivierung einfacher Arene
2012
The recent development of efficient Earth-abundant transition-metal nanocatalysts
2017
Metal-free transfer hydrogenation of olefins via dehydrocoupling catalysis
2014
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Tandem C–C Bond Cleavage of Cyclopropanols and Oxidative Aromatization by Manganese(IV) Oxide in a Direct C–H to C–C Functionalization of Heteroaromatics
2015
The impact of Novel Process Windows on the Claisen rearrangement
2013
Batch‐ and Continuous‐Flow Aerobic Oxidation of 14‐Hydroxy Opioids to 1,3‐Oxazolidines—A Concise Synthesis of Noroxymorphone
2016
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Light-Controlled Radical Polymerization: Mechanisms, Methods, and Applications
2016 Standout
Base‐Free Transfer Hydrogenation of Nitroarenes Catalyzed by Micro‐Mesoporous Iron Oxide
2016
Iron-Catalyzed Amination of Sulfides and Sulfoxides with Azides in Photochemical Continuous Flow Synthesis
2016
Photoredox Catalysis in Organic Chemistry
2016 Standout
Photocatalytic CH Activation by Hydrogen‐Atom Transfer in Synthesis
2015
Flow Chemistry on Multigram Scale: Continuous Synthesis of Boronic Acids within 1 s
2016
Carbon–Carbon Bond Forming Reactions via Photogenerated Intermediates
2016
Nitrogen and oxygen-doped metal-free carbon catalysts for chemoselective transfer hydrogenation of nitrobenzene, styrene, and 3-nitrostyrene with hydrazine
2014
Dendrimer‐Encapsulated Palladium Nanoparticles for Continuous‐Flow Suzuki–Miyaura Cross‐Coupling Reactions
2015
Synergistic Manganese(I) C−H Activation Catalysis in Continuous Flow: Chemoselective Hydroarylation
2017
Nitroarene reduction: a trusted model reaction to test nanoparticle catalysts
2015
Frustrated Lewis Pairs
2015 Standout
Continuous photochemistry: the flow synthesis of ibuprofen via a photo-Favorskii rearrangement
2015
Cobalt mediated C–H bond functionalization: emerging tools for organic synthesis
2014
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Reaction screening in continuous flow reactors
2016
Dichloromethyllithium: Synthesis and Application in Continuous Flow Mode
2017
Generation and Synthetic Application of Trifluoromethyl Diazomethane Utilizing Continuous Flow Technologies
2016
Review on selective hydrogenation of nitroarene by catalytic, photocatalytic and electrocatalytic reactions
2018
Chemistry Takes a Bath: Reactions in Aqueous Media
2018 StandoutNobel
Applications of Fluorine in Medicinal Chemistry
2015 Standout
CF2H, a Hydrogen Bond Donor
2017 Standout
Continuous flow Negishi cross-couplings employing silica-supported Pd-PEPPSI–IPr precatalyst
2016
Heterocyclic Nanographenes and Other Polycyclic Heteroaromatic Compounds: Synthetic Routes, Properties, and Applications
2016 Standout
Greener and Sustainable Trends in Synthesis of Organics and Nanomaterials
2016
Leaching‐Free Supported Gold Nanoparticles Catalyzing Cycloisomerizations under Microflow Conditions
2015
Continuous flow biocatalysis
2018
Controlled Flow Precipitation as a Valuable Tool for Synthesis
2015
A Computational Study: Reactivity Difference between Phosphine- and Amine-Catalyzed Cycloadditions of Allenoates and Enones
2014
Metal-Free Photocatalytic Radical Trifluoromethylation Utilizing Methylene Blue and Visible Light Irradiation
2014
Biphasic Catalytic Hydrogen Peroxide Oxidation of Alcohols in Flow: Scale-up and Extraction
2016
Continuous flow hydrogenation of nitroarenes, azides and alkenes using maghemite–Pd nanocomposites
2015
Chemo-, Regio-, and Stereoselective Trifluoromethylation of Styrenes via Visible Light-Driven Single-Electron Transfer (SET) and Triplet–Triplet Energy Transfer (TTET) Processes
2014
A combination of natural deep eutectic solvents and microflow technology: a sustainable innovation for the tandem synthesis of 3-aminohexahydrocoumarins
2016
Exploring New Parameter Spaces for the Oxidative Homocoupling of Aniline Derivatives: Sustainable Synthesis of Azobenzenes in a Flow System
2015
Benzylamines via Iron-Catalyzed Direct Amination of Benzyl Alcohols
2015 StandoutNobel
A mild and fast photocatalytic trifluoromethylation of thiols in batch and continuous-flow
2014
Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry
2013
Pd Metal Catalysts for Cross-Couplings and Related Reactions in the 21st Century: A Critical Review
2018
Works of David Cantillo being referenced
Assessing the whole range of CuAAC mechanisms by DFT calculations—on the intermediacy of copper acetylides
2011
Light‐Induced CH Arylation of (Hetero)arenes by In Situ Generated Diazo Anhydrides
2015
In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous‐Flow Transfer Hydrogenation of Olefins
2013
Direct Arylation of Benzene with Aryl Bromides using High‐Temperature/High‐Pressure Process Windows: Expanding the Scope of CH Activation Chemistry
2012
In Situ Generated Iron Oxide Nanocrystals as Efficient and Selective Catalysts for the Reduction of Nitroarenes using a Continuous Flow Method
2012
Continuous‐Flow Technology—A Tool for the Safe Manufacturing of Active Pharmaceutical Ingredients
2015 Standout
Hydrazine-mediated Reduction of Nitro and Azide Functionalities Catalyzed by Highly Active and Reusable Magnetic Iron Oxide Nanocrystals
2013
Continuous Flow α-Trifluoromethylation of Ketones by Metal-Free Visible Light Photoredox Catalysis
2014
A Unified Mechanistic View on the Morita−Baylis−Hillman Reaction: Computational and Experimental Investigations
2010
Sequential Nitration/Hydrogenation Protocol for the Synthesis of Triaminophloroglucinol: Safe Generation and Use of an Explosive Intermediate under Continuous-Flow Conditions
2014
In Situ Generated Iron Oxide Nanocrystals as Efficient and Selective Catalysts for the Reduction of Nitroarenes using a Continuous Flow Method
2012
Kontinuierliche Durchflussverfahren: ein Werkzeug für die sichere Synthese von pharmazeutischen Wirkstoffen
2015
Direct Preparation of Nitriles from Carboxylic Acids in Continuous Flow
2013
A Continuous-Flow Protocol for Light-Induced Benzylic Fluorinations
2014
In Situ Generation of Diimide from Hydrazine and Oxygen: Continuous‐Flow Transfer Hydrogenation of Olefins
2013
Visible-light photoredox catalysis using a macromolecular ruthenium complex: reactivity and recovery by size-exclusion nanofiltration in continuous flow
2016
Safe generation and use of bromine azide under continuous flow conditions – selective 1,2-bromoazidation of olefins
2015
Continuous Flow Synthesis of a Key 1,4-Benzoxazinone Intermediate via a Nitration/Hydrogenation/Cyclization Sequence
2016
A Scalable Procedure for Light-Induced Benzylic Brominations in Continuous Flow
2013
Mechanistic Insights on the Ruthenium‐Catalyzed Hydrogenation of Amides – C–N vs. C–O Cleavage
2011
On the Fischer Indole Synthesis of 7-Ethyltryptophol—Mechanistic and Process Intensification Studies under Continuous Flow Conditions
2013
Halogenation of organic compounds using continuous flow and microreactor technology
2016
Flash Flow Pyrolysis: Mimicking Flash Vacuum Pyrolysis in a High-Temperature/High-Pressure Liquid-Phase Microreactor Environment
2012
A laboratory-scale continuous flow chlorine generator for organic synthesis
2016
Mechanistic Insights on Azide−Nitrile Cycloadditions: On the Dialkyltin Oxide−Trimethylsilyl Azide Route and a New Vilsmeier−Haack-Type Organocatalyst
2011
Immobilized Transition Metals as Catalysts for Cross‐Couplings in Continuous Flow—A Critical Assessment of the Reaction Mechanism and Metal Leaching
2014
Benchmarking Immobilized Di- and Triarylphosphine Palladium Catalysts for Continuous-Flow Cross-Coupling Reactions: Efficiency, Durability, and Metal Leaching Studies
2015