Citation Impact
Citing Papers
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
PDE4 cAMP-specific phosphodiesterases
2001
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
A stomatin-like protein necessary for mechanosensation in C. elegans
1995 StandoutNatureNobel
The Highly Cooperative Folding of Small Naturally Occurring Proteins Is Likely the Result of Natural Selection
2007 StandoutNobel
Destabilization of the complete protein secondary structure on binding to the chaperone GroEL
1994 StandoutNatureNobel
Structural determinants of peptide-binding orientation and of sequence specificity in SH3 domains
1994 Nature
Distance geometry and related methods for protein structure determination from NMR data
1987
Jaks and Stats in signaling by the cytokine receptor superfamily
1995 Standout
High-resolution crystal structures of tyrosine kinase SH3 domains complexed with proline-rich peptides
1994
Three-Dimensional Structure of an Evolutionarily Conserved N-Terminal Domain of Syntaxin 1A
1998 StandoutNobel
Cancer drug resistance: an evolving paradigm
2013 Standout
Wnt Signaling and an APC-Related Gene Specify Endoderm in Early C. elegans Embryos
1997 StandoutNobel
Hierarchical Modeling of Activation Mechanisms in the ABL and EGFR Kinase Domains: Thermodynamic and Mechanistic Catalysts of Kinase Activation by Cancer Mutations
2009
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Protein-peptide interactions
1995
Modeller: Generation and Refinement of Homology-Based Protein Structure Models
2003
Refined crystal structure of troponin C from turkey skeletal muscle at 2·0 Å resolution
1988
Molecular Tuning of Ion Binding to Calcium Signaling Proteins
1994
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
The 13C Chemical-Shift Index: A simple method for the identification of protein secondary structure using 13C chemical-shift data
1994 Standout
Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins
1989 Nature
Direct Binding of Activated c-Src to the β3-Adrenergic Receptor Is Required for MAP Kinase Activation
2000 StandoutNobel
NMR structure of cyclosporin A bound to cyclophilin in aqueous solution
1991
Modular binding domains in signal transduction proteins
1995
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy
1991 StandoutNatureNobel
Ba/F3 cells and their use in kinase drug discovery
2006
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
The role of protein surface charges in ion binding
1988 Nature
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Turn stability in β‐hairpin peptides: Investigation of peptides containing 3:5 type I G1 bulge turns
2003
Protein modules and signalling networks
1995 StandoutNature
Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain
2005 Standout
Crystal structure of the Src family tyrosine kinase Hck
1997 Nature
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
CASK Functions as a Mg2+-Independent Neurexin Kinase
2008 StandoutNobel
Crystal structure of the tyrosine kinase domain of the human insulin receptor
1994 Nature
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
1998 StandoutNatureNobel
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Orientation of Peptide Fragments from Sos Proteins Bound to the N-Terminal SH3 Domain of Grb2 Determined by NMR Spectroscopy
1994
Functional rapidly folding proteins from simplified amino acid sequences
1997 StandoutNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques
1994
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
The B7 and CD28 receptor families
1994
Candidate Adaptor Protein CED-6 Promotes the Engulfment of Apoptotic Cells in C. elegans
1998
hCASK and hDlg Associate in Epithelia, and Their Src Homology 3 and Guanylate Kinase Domains Participate in Both Intramolecular and Intermolecular Interactions
2000
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
Crystal Structures of a Complexed and Peptide-Free Membrane Protein–Binding Domain: Molecular Basis of Peptide Recognition by PDZ
1996 StandoutNobel
Calcium and Plant Development
1985
The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C.
1994
Interaction of Grb2 via its Src homology 3 domains with synaptic proteins including synapsin I.
1994
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules.
1995
WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome.
1996
Protein Structure Determination in Solution by Nuclear Magnetic Resonance Spectroscopy
1989 StandoutScienceNobel
A ligand-reversible dimerization system for controlling protein–protein interactions
2000
Mutation of the mouse klotho gene leads to a syndrome resembling ageing.
1997 Standout
Mutant Potassium Channels with Altered Binding of Charybdotoxin, a Pore-Blocking Peptide Inhibitor
1989 StandoutScienceNobel
Ca2+ binding and conformational change in two series of point mutations to the individual Ca(2+)-binding sites of calmodulin.
1992
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1.
1994
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Proton-detected heteronuclear edited and correlated nuclear magnetic resonance and nuclear Overhauser effect in solution
1987
Polypeptide fold in the two metal clusters of metallothionein-2 by nuclear magnetic resonance in solution
1986 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
A general approach for chemical labeling and rapid, spatially controlled protein inactivation
2004
NMR Determination of Residual Structure in a Urea-Denatured Protein, the 434-Repressor
1992 StandoutScienceNobel
Recognition of Unique Carboxyl-Terminal Motifs by Distinct PDZ Domains
1997 Science
Bipartite Ca 2+ -Binding Motif in C 2 Domains of Synaptotagmin and Protein Kinase C
1996 StandoutScienceNobel
Two Binding Orientations for Peptides to the Src SH3 Domain: Development of a General Model for SH3-Ligand Interactions
1994 Science
Assembly of Cell Regulatory Systems Through Protein Interaction Domains
2003 Science
Identification of Src, Fyn, Lyn, PI3K and Abl SH3 domain ligands using phage display libraries.
1994
The Yin and Yang of T Cell Costimulation
1995 StandoutScienceNobel
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Progress in Modeling of Protein Structures and Interactions
2005 StandoutScienceNobel
Interaction of calmodulin and a calmodulin-binding peptide from myosin light chain kinase: major spectral changes in both occur as the result of complex formation
1985 StandoutNobel
Three-dimensional structure of calmodulin
1985 StandoutNature
Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor.
1996 StandoutNobel
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
An SH3 binding region in the epithelial Na+ channel (alpha rENaC) mediates its localization at the apical membrane.
1994
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
Enhancement of Antitumor Immunity by CTLA-4 Blockade
1996 StandoutScienceNobel
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Attenuated T 2 relaxation by mutual cancellation of dipole–dipole coupling and chemical shift anisotropy indicates an avenue to NMR structures of very large biological macromolecules in solution
1997 StandoutNobel
The Caenorhabditis elegans gene lin-17, which is required for certain asymmetric cell divisions, encodes a putative seven-transmembrane protein similar to the Drosophila frizzled protein.
1996 StandoutNobel
Two Identical Noninteracting Sites in an Ion Channel Revealed by Proton Transfer
1994 StandoutScienceNobel
Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.
1996 Nobel
Receptor-Induced Conformation Change of the Immunosuppressant Cyclosporin A
1991 StandoutScienceNobel
Cytoplasmic calcium regulates voltage-dependent ion channels in plant vacuoles
1987 StandoutNatureNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Azidotyrosylcalmodulin derivatives. Specific probes for protein-binding domains.
1984
Works of David C. Dalgarno being referenced
Structural Mechanism of the Pan‐BCR‐ABL Inhibitor Ponatinib (AP24534): Lessons for Overcoming Kinase Inhibitor Resistance
2010
Crystal Structure of the T315I Mutant of Abl Kinase
2007
Intravenous Safety and Pharmacokinetics of a Novel Dimerizer Drug, AP1903, in Healthy Volunteers
2001
Structural basis for the binding of proline-rich peptides to SH3 domains
1994
The carboxyl-terminal region of human interferon γ is important for biological activity: mutagenic and NMR analysis
1991
SH3 domains and drug design: Ligands, structure, and biological function
1997
Src Homology-2 Inhibitors: Peptidomimetic and Nonpeptide
2002
Structural information from NMR secondary chemical shifts of peptide α C-H protons in proteins
1983
Two-dimensional proton-cadmium-113 chemical-shift correlation maps by proton-detected multiple-quantum NMR in metal complexes and metalloproteins
1985
Investigating Protein−Ligand Interactions with a Mutant FKBP Possessing a Designed Specificity Pocket
2000
Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance
2006
1H NMR studies of calmodulin
1984
Proton‐NMR studies of the solution conformations of vitamin‐D‐induced bovine intestinal calcium‐binding protein
1983
1H and 15N assignments and secondary structure of the PI3K SH3 domain
1993
1H‐NMR studies of calmodulin
1984
The nature of the trifluoperazine binding sites on calmodulin and troponin-C
1984
Inhibition of wild-type and mutant Bcr-Abl by AP23464, a potent ATP-based oncogenic protein kinase inhibitor: implications for CML
2004
The dynamics and function of calcium-binding proteins
1983
Proton NMR studies on bovine cyclophilin: preliminary structural characterization of this specific cyclosporin A binding protein
1986