Citation Impact
Citing Papers
Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen
2001
Regulation of Angiogenesis by Oxygen and Metabolism
2009
Hallmarks of Cancer: The Next Generation
2011 Standout
Cyclooxygenase Isozymes: The Biology of Prostaglandin Synthesis and Inhibition
2004 Standout
Overexpression of Cyclooxygenase-2 Is Sufficient to Induce Tumorigenesis in Transgenic Mice
2001
Thiazolidinediones
2004 Standout
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Hyaluronan Fragments Induce Nitric-oxide Synthase in Murine Macrophages through a Nuclear Factor κB-dependent Mechanism
1997
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Inflammation and metabolic disorders
2006 StandoutNature
Enhanced angiogenesis in obesity and in response to PPARγ activators through adipocyte VEGF and ANGPTL4 production
2008
Colocalization and Interaction of Cyclooxygenase-2 with Caveolin-1 in Human Fibroblasts
2001
Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes
2013 Standout
Effects of Torcetrapib in Patients at High Risk for Coronary Events
2007 Standout
Ibuprofen-like activity in extra-virgin olive oil
2005 StandoutNature
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Increased Angiogenesis Protects against Adipose Hypoxia and Fibrosis in Metabolic Disease-resistant 11β-Hydroxysteroid Dehydrogenase Type 1 (HSD1)-deficient Mice
2011 StandoutNobel
The Failing Heart — An Engine Out of Fuel
2007 Standout
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
Cyclooxygenase knockout mice
1999
Impaired mucosal defense to acute colonic injury in mice lacking cyclooxygenase-1 or cyclooxygenase-2
2000 StandoutNobel
Shared Principles in NF-κB Signaling
2008 Standout
Comparison of Upper Gastrointestinal Toxicity of Rofecoxib and Naproxen in Patients with Rheumatoid Arthritis
2000 Standout
Hypoxia and Inflammation
2011 Standout
Peroxisome proliferator activated‐receptor agonism and left ventricular remodeling in mice with chronic myocardial infarction
2004
PharmGKB summary
2010
Involvement of nuclear factor kB in the regulation of cyclooxygenase‐2 expression by interleukin‐1 in rheumatoid synoviocytes
1997
The changing landscape of atherosclerosis
2021 StandoutNature
Magnesium Replacement Improves the Metabolic Profile in Obese and Pre-Diabetic Patients with Mild-to-Moderate Chronic Kidney Disease: A 3-Month, Randomised, Double-Blind, Placebo-Controlled Study
2017 Standout
Lipidomic Profiling of Influenza Infection Identifies Mediators that Induce and Resolve Inflammation
2013
Cardiovascular Risk Associated with Celecoxib in a Clinical Trial for Colorectal Adenoma Prevention
2005 Standout
Human nutrition, the gut microbiome and the immune system
2011 StandoutNature
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
2007 StandoutNature
Missing Pieces in the NF-κB Puzzle
2002 Standout
Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison
1999
The biochemistry and medical significance of the flavonoids
2002 Standout
Interactions between inducible isoforms of nitric oxide synthase and cyclo‐oxygenase in vivo: investigations using the selective inhibitors, 1400W and celecoxib
1998
Sodium Salicylate Inhibits Cyclo-Oxygenase-2 Activity Independently of Transcription Factor (Nuclear Factor κB) Activation: Role of Arachidonic Acid
1997
Rat colorectal tumours treated with a range of non-steroidal anti-inflammatory drugs show altered cyclooxygenase-2 and cyclooxygenase-1 splice variant mRNA expression levels
2001
Leptomycin B, an Inhibitor of the Nuclear Export Receptor CRM1, Inhibits COX-2 Expression
2003
15-Deoxy-Δ12,14-prostaglandin J2
2002
The structures of prostaglandin endoperoxide H synthases-1 and -2
2002
Arachidonic Acid Is Preferentially Metabolized by Cyclooxygenase-2 to Prostacyclin and Prostaglandin E2
1999
Cyclooxygenase-1-Coupled Prostaglandin Biosynthesis Constitutes an Essential Prerequisite for Skin Repair
2003
NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti
2000
Inflammation in Hypertension
2020
Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo
2001
Combinatorial roles of nuclear receptors in inflammation and immunity
2005
Significant Roles of Inducible Cyclooxygenase (COX)-2 in Angiogenesis in Rat Sponge Implants.
1997
Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: Implications for gastrointestinal toxicity
1998
Induction of cyclo‐oxygenase‐2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone
1994 Nobel
Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate
1999
Overexpression of Cyclooxygenase-2 Induces Cell Cycle Arrest
1999
Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse
1995 StandoutNobel
Augmented Expression of Cyclooxygenase-2 in Human Atherosclerotic Lesions
1999
Systemic Inflammation and Skeletal Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: State of the Art and Novel Insights in Regulation of Muscle Plasticity
2007
Eicosanoids and the gastrointestinal tract
1995
Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.
1996
New insights into the mode of action of anti-inflammatory drugs
1995 Nobel
Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents
1996 StandoutNature
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Recognition of Hyaluronan Released in Sterile Injury Involves a Unique Receptor Complex Dependent on Toll-like Receptor 4, CD44, and MD-2
2007 StandoutNobel
Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
2010
Pharmacology and therapeutics of omega-3 polyunsaturated fatty acids in chronic inflammatory disease
2013
Points of control in inflammation
2002 StandoutNature
The PI3K Pathway in Human Disease
2017 Standout
Polyamines and cancer: old molecules, new understanding
2004
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice
2005
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
HDL as a target in the treatment of atherosclerotic cardiovascular disease
2005
Cyclooxygenase-2: Regulation and relevance in inflammation
1995
On the Evolutionary Origin of Cyclooxygenase (COX) Isozymes
2004
Bifidobacteria can protect from enteropathogenic infection through production of acetate
2011 StandoutNature
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
1995 Standout
Modular Activation of Nuclear Factor-κB Transcriptional Programs in Human Diabetic Nephropathy
2006
Roles of PPARs in health and disease
2000 StandoutNature
Regulation of cyclooxygenase enzymes by nitric oxide
1997
The roles of CYP450 epoxygenases and metabolites, epoxyeicosatrienoic acids, in cardiovascular and malignant diseases
2011
Inhibition of Cyclooxygenase-2 Rapidly Reverses Inflammatory Hyperalgesia and Prostaglandin E2 Production
1997
Identification of vascular endothelial genes differentially responsive to fluid mechanical stimuli: cyclooxygenase-2, manganese superoxide dismutase, and endothelial cell nitric oxide synthase are selectively up-regulated by steady laminar shear stress.
1996
Angiopoietin-like 4 is a potent angiogenic factor and a novel therapeutic target for patients with proliferative diabetic retinopathy
2015 StandoutNobel
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Peroxisome Proliferator-Activated Receptor-β/δ Regulates Angiogenic Cell Behaviors and Oxygen-Induced Retinopathy
2013
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 Standout
Human inflammatory and resolving lipid mediator responses to resistance exercise and ibuprofen treatment
2013
Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis
2015 StandoutNobel
Conditional Disruption of the Peroxisome Proliferator-Activated Receptor γ Gene in Mice Results in Lowered Expression of ABCA1, ABCG1, and apoE in Macrophages and Reduced Cholesterol Efflux
2002
Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4.
2003
Cyclo‐oxygenase and nitric oxide synthase isoforms in rat carrageenin‐induced pleurisy
1994
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Spermidine in health and disease
2018 StandoutScience
The Effect of Thiazolidinediones on Plasma Adiponectin Levels in Normal, Obese, and Type 2 Diabetic Subjects
2002
Role of Prostacyclin in the Cardiovascular Response to Thromboxane A 2
2002 StandoutScience
Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists
2002 StandoutScience
Cyclooxygenase-1 and an alternatively spliced mRNA in the rat stomach: effects of aging and ulcers
2000
2012
The gut microbiota as an environmental factor that regulates fat storage
2004 Standout
Oxidized omega-3 fatty acids in fish oil inhibit leukocyte-endothelial interactions through activation of PPARα
2002
Upregulation of COX-2 in cerebral microvascular endothelial cells by smooth muscle cell signals
1997
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Peroxisome Proliferator-Activated Receptors: Nuclear Control of Metabolism*
1999 Standout
The Kinetic Factors That Determine the Affinity and Selectivity for Slow Binding Inhibition of Human Prostaglandin H Synthase 1 and 2 by Indomethacin and Flurbiprofen
1996
Failure of ductus arteriosus closure and remodeling in neonatal mice deficient in cyclooxygenase-1 and cyclooxygenase-2
2001 StandoutNobel
Peroxisome Proliferator-Activated Receptor γ Target Gene Encoding a Novel Angiopoietin-Related Protein Associated with Adipose Differentiation
2000
Impaired Myocardial Fatty Acid Oxidation and Reduced Protein Expression of Retinoid X Receptor-α in Pacing-Induced Heart Failure
2002
Clinical Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity in Adults--The Evidence Report. National Institutes of Health.
1998 Standout
Specific NF‐κB blockade selectively inhibits tumour necrosis factor‐α‐induced COX‐2 but not constitutive COX‐1 gene expression in HT‐29 cells
1998
Works of David Bishop‐Bailey being referenced
The Role of PPARs in the Endothelium: Implications for Cancer Therapy
2008
Peroxisome proliferator-activated receptors and inflammation
2005
Cyclo-oxygenase-2 Regulates Inducible ICAM-1 and VCAM-1 Expression in Human Vascular Smooth Muscle Cells
1998
Epoxygenases and peroxisome proliferator‐activated receptors in mammalian vascular biology
2007
15-deoxy-Δ12,14-PGJ2 induces synoviocyte apoptosis and suppresses adjuvant-induced arthritis in rats
2000
Characterization of the induction of nitric oxide synthase and cyclo‐oxygenase in rat aorta in organ culture
1997
Peroxisome proliferator-activated receptors: a critical review on endogenous pathways for ligand generation
2003
Peroxisome proliferator‐activated receptors in the cardiovascular system
2000
Cyclooxygenase-1 and -2 isoenzymes
1999
Emerging roles of peroxisome proliferator-activated receptor-β/δ in inflammation
2009
The Epoxygenases CYP2J2 Activates the Nuclear Receptor PPARα In Vitro and In Vivo
2009
Role for Nuclear Factor-κB and Signal Transducer and Activator of Transcription 1/Interferon Regulatory Factor-1 in Cytokine-Induced Endothelin-1 Release in Human Vascular Smooth Muscle Cells
2003
Endothelial Cell Apoptosis Induced by the Peroxisome Proliferator-activated Receptor (PPAR) Ligand 15-Deoxy-Δ12,14-prostaglandin J2
1999
Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation.
1994 Nobel
Induction of Cyclooxygenase-2 in Human Saphenous Vein and Internal Mammary Artery
1997
Expression and activation of the farnesoid X receptor in the vasculature
2004
Activation of Peroxisome Proliferator-Activated Receptors in Human Airway Smooth Muscle Cells Has a Superior Anti-inflammatory Profile to Corticosteroids: Relevance for Chronic Obstructive Pulmonary Disease Therapy
2003
Activation of PPARβ/δ Induces Endothelial Cell Proliferation and Angiogenesis
2006
Anti-Inflammatory Effects of Epoxyeicosatrienoic Acids
2012
Prostaglandins and the Regulation of Tumor Growth
2002
The Nuclear Receptor PPARγ and Immunoregulation: PPARγ Mediates Inhibition of Helper T Cell Responses
2000
Expression of peroxisome proliferator-activated receptor (PPAR)-gamma in human lung cancer.
2001