Citation Impact
Citing Papers
CDK 4/6 Inhibitor Palbociclib (PD0332991) in Rb+ Advanced Breast Cancer: Phase II Activity, Safety, and Predictive Biomarker Assessment
2014
Combined MEK and PI3K Inhibition in a Mouse Model of Pancreatic Cancer
2014
Early Adaptation and Acquired Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer
2016
BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance
2016
miR-424(322)/503 is a breast cancer tumor suppressor whose loss promotes resistance to chemotherapy
2017
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Challenges and strategies in anti-cancer nanomedicine development: An industry perspective
2016
Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study
2021 Standout
pH-responsive high stability polymeric nanoparticles for targeted delivery of anticancer therapeutics
2020
Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer
2019 StandoutNobel
The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
2022
The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study
2014 Standout
Engineering precision nanoparticles for drug delivery
2020 Standout
Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
2019
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
2014 Standout
Breast cancer
2016 Standout
Heat shock protein 90: its inhibition and function
2017
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Hydrophobic mismatch drives self-organization of designer proteins into synthetic membranes
2024 StandoutNobel
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Palbociclib: an evidence-based review of its potential in the treatment of breast cancer
2014
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells
2022 StandoutNobel
The biology and management of non-small cell lung cancer
2018 StandoutNature
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
2023 StandoutNobel
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
2015
The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer
2016
Correction: CDK4/ 6 inhibition provides a potent adjunct to Her2- targeted therapies in preclinical breast cancer models
2021
Hallmarks of aging: An expanding universe
2023 Standout
Targeting cell cycle and hormone receptor pathways in cancer
2013
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Autophagy and senescence, converging roles in pathophysiology as seen through mouse models
2021
The biology and function of fibroblasts in cancer
2016 Standout
Brief update on endocytosis of nanomedicines
2019
Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
2017 Nature
Cancer stem cells revisited
2017 Standout
An ionizable lipid toolbox for RNA delivery
2021 StandoutNobel
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Prognostic Significance in Breast Cancer of a Gene Signature Capturing Stromal PDGF Signaling
2013
Improving cancer immunotherapy through nanotechnology
2019
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
EMT Inducers Catalyze Malignant Transformation of Mammary Epithelial Cells and Drive Tumorigenesis towards Claudin-Low Tumors in Transgenic Mice
2012
Metazoan MicroRNAs
2018 Standout
Forging a signature of in vivo senescence
2015
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
nab-Paclitaxel plus carboplatin or gemcitabine versus gemcitabine plus carboplatin as first-line treatment of patients with triple-negative metastatic breast cancer: results from the tnAcity trial
2018
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
2019 Standout
PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types
2013
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
2019
Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
2020
Clonal Expansion and Diversification of Cancer-Associated Mutations in Endometriosis and Normal Endometrium
2018
Cyclin-dependent kinase inhibitor therapy for hematologic malignancies
2013
Hallmarks of Cellular Senescence
2018 Standout
Cellular senescence and its effector programs
2014
Senescent cell turnover slows with age providing an explanation for the Gompertz law
2019
Mitochondria as multifaceted regulators of cell death
2019 Standout
The role of senescent cells in ageing
2014 StandoutNature
A minimal physiologically based pharmacokinetic model that predicts anti-PEG IgG-mediated clearance of PEGylated drugs in human and mouse
2018
Meta-analysis of clinical and preclinical studies comparing the anticancer efficacy of liposomal versus conventional non-liposomal doxorubicin
2016
Palbociclib and Letrozole in Advanced Breast Cancer
2016 Standout
Revisiting STAT3 signalling in cancer: new and unexpected biological functions
2014 Standout
The PI3K Pathway in Human Disease
2017 Standout
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
STING agonist delivery by tumour-penetrating PEG-lipid nanodiscs primes robust anticancer immunity
2022
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
The history and future of targeting cyclin-dependent kinases in cancer therapy
2015 Standout
Cellular senescence: from physiology to pathology
2014 Standout
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
A Nitro‐Modified Luminescent Hydrogen‐Bonded Organic Framework for Non‐Contact and High‐Contrast Sensing of Aromatic Amines
2023 StandoutNobel
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Effective use of PI3K inhibitor BKM120 and PARP inhibitor Olaparib to treat PIK3CA mutant ovarian cancer
2016
Aggregation‐Induced Emission: The Whole Is More Brilliant than the Parts
2014 Standout
Potent STING activation stimulates immunogenic cell death to enhance antitumor immunity in neuroblastoma
2020
Molecular Pathways: CDK4 Inhibitors for Cancer Therapy
2014
Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity
2022 StandoutNobel
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics
2015
Cells exhibiting strong p16 INK4a promoter activation in vivo display features of senescence
2019
In Vivo mRNA CAR T Cell Engineering via Targeted Ionizable Lipid Nanoparticles with Extrahepatic Tropism
2023 StandoutNobel
Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL −/− clear cell renal carcinoma
2017 StandoutNobel
Inhibition of CDK4/6 protects against radiation-induced intestinal injury in mice
2016
Covalent Organic Frameworks: Design, Synthesis, and Functions
2020 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models
2014
Comparison of RNA-Seq by poly (A) capture, ribosomal RNA depletion, and DNA microarray for expression profiling
2014
Engineered PLGA microparticles for long-term, pulsatile release of STING agonist for cancer immunotherapy
2020
Recent advances in organic thermally activated delayed fluorescence materials
2017 Standout
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
2016
Endometriosis
2020 Standout
The Binding Site Barrier Elicited by Tumor-Associated Fibroblasts Interferes Disposition of Nanoparticles in Stroma-Vessel Type Tumors
2016
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
A reanalysis of nanoparticle tumor delivery using classical pharmacokinetic metrics
2020
Mouse Models to Disentangle the Hallmarks of Human Aging
2018
Targeting CDK4 and CDK6: From Discovery to Therapy
2015
Tetraphenylethylene Conjugated with a Specific Peptide as a Fluorescence Turn‐On Bioprobe for the Highly Specific Detection and Tracing of Tumor Markers in Live Cancer Cells
2013
The Effects of Nanoparticle Drug Loading on the Pharmacokinetics of Anticancer Agents
2015
The chemistry of senescence
2019
CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer
2014
p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli
2017
CDK4/6 inhibition induces epithelial cell cycle arrest and ameliorates acute kidney injury
2013
MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition
2015
Atezolizumab and Nab-Paclitaxel in Advanced Triple-Negative Breast Cancer
2018 Standout
Anti–PD-1 Checkpoint Therapy Can Promote the Function and Survival of Regulatory T Cells
2021
The Molecular Balancing Act of p16INK4a in Cancer and Aging
2013
Works of David B. Darr being referenced
Effects of Tumor Microenvironment Heterogeneity on Nanoparticle Disposition and Efficacy in Breast Cancer Tumor Models
2014
Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA -Mutated and BRCA –Wild-Type Triple-Negative Breast Cancer
2015
Predicting Drug Responsiveness in Human Cancers Using Genetically Engineered Mice
2013
Combined PI3K/mTOR and MEK Inhibition Provides Broad Antitumor Activity in Faithful Murine Cancer Models
2012
Multiple Roles of Cyclin-Dependent Kinase 4/6 Inhibitors in Cancer Therapy
2012
A nanoparticle-incorporated STING activator enhances antitumor immunity in PD-L1–insensitive models of triple-negative breast cancer
2018
Pharmacokinetics and Efficacy of PEGylated Liposomal Doxorubicin in an Intracranial Model of Breast Cancer
2013
Coexistent ARID1A–PIK3CA mutations promote ovarian clear-cell tumorigenesis through pro-tumorigenic inflammatory cytokine signalling
2015
Monitoring Tumorigenesis and Senescence In Vivo with a p16INK4a-Luciferase Model
2013
Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer
2016
Overview of Genetically Engineered Mouse Models of Distinct Breast Cancer Subtypes
2016
A Fluorescent Hsp90 Probe Demonstrates the Unique Association between Extracellular Hsp90 and Malignancy in Vivo
2017
Comparative oncogenomics identifies breast tumors enriched in functional tumor-initiating cells
2011
Erythropoietin promotes breast tumorigenesis through tumor-initiating cell self-renewal
2014