Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Electrically monitoring DNA repair by photolyase
2005 StandoutNobel
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
Antisense properties of peptide nucleic acid
1999
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen
2001
Preventive and therapeutic vaccines for human papillomavirus-associated cervical cancers
2000
Channel opening and gating mechanism in AMPA-subtype glutamate receptors
2017 StandoutNatureNobel
Generation of a packaging cell line for prolonged large‐scale production of high‐titer HIV‐1‐based lentiviral vector
2005
Efficient pH-independent sequence-specific DNA binding by pseudoisocytosine-containing bis-PNA
1995
Identification of Mutations in a Sindbis Virus Variant Able to Establish Persistent Infection in BHK Cells: The Importance of a Mutation in the nsP2 Gene
1997
Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media
2007
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
Biological Activity and Biotechnological Aspects of Peptide Nucleic Acid
2006
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
Template switching between PNA and RNA oligonucleotides
1995 Nature
Screening and large-scale expression of membrane proteins in mammalian cells for structural studies
2014
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
PNA-nucleic acid complexes. Structure, stability and dynamics
1996
DNA-like double helix formed by peptide nucleic acid
1994 Nature
Cancer therapy using a self-replicating RNA vaccine
1999
Assessment of telomere length and factors that contribute to its stability
2003
Site‐Directed RNA Editing with Antagomir Deaminases — A Tool to Study Protein and RNA Function
2014
Modulating PNA/DNA Hybridization by Light
2010
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Synthesis and Helical Structure of Spiroborate‐Based Double‐Stranded Helicate with Oligophenol Strands Bearing Bipyridine Units
2011
Strategies for designing and optimizing new generation vaccines
2001
State-of-the-art of the production of retroviral vectors
2004
Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice
1999 StandoutNobel
Bicyclo(3.2.1]-DNA, a new DNA analog with a rigid backbone and flexibly linked bases: pairing properties with complementary DNA
1998
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Switching and Signaling at the Telomere
2001 StandoutNobel
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
The neonatal Fc receptor, FcRn, as a target for drug delivery and therapy
2015
Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry
1998
Sindbis virus vectors for expression in animal cells
1996
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
Heterogeneity in telomere length of human chromosomes
1996
Double helix formation of poly(m-phenylene)s bearing achiral oligo(ethylene oxide) pendants and transformation into an excess of one-handed single helix through cholate binding in water
2009
Structural Characterization of PNA-DNA Duplexes by NMR. Evidence for DNA in a B-like Conformation
1994
Enhancing immune responses using suicidal DNA vaccines
1998
Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes
2016 StandoutNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Use of Conventional or Replicating Nucleic Acid-Based Vaccines and Recombinant Semliki Forest Virus-Derived Particles for the Induction of Immune Responses Against Hepatitis C Virus Core and E2 Antigens
2000
Enhancement of Sindbis Virus Self-Replicating RNA Vaccine Potency by Targeting Antigen to Endosomal/Lysosomal Compartments
2001
Elucidation of AMPA receptor–stargazin complexes by cryo–electron microscopy
2016 StandoutScienceNobel
Transition metal labels on peptide nucleic acid (PNA) monomers
1999
Induction of Broad CD4+and CD8+T-Cell Responses and Cross- Neutralizing Antibodies against Hepatitis C Virus by Vaccination with Th1-Adjuvanted Polypeptides Followed by Defective Alphaviral Particles Expressing Envelope Glycoproteins gpE1 and gpE2 and Nonstructural Proteins 3, 4, and 5
2008 StandoutNobel
Roles of Nonstructural Protein nsP2 and Alpha/Beta Interferons in Determining the Outcome of Sindbis Virus Infection
2002 StandoutNobel
Haploinsufficiency of mTR results in defects in telomere elongation
2002 StandoutNobel
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
PNAs: synthetische Polyamidnucleinsäuren mit außergewöhnlichen Bindungseigenschaften
1998
Bioorganometallic Chemistry of Ferrocene
2004 Standout
Synthesis and Properties of 2′‐Deoxy‐1′,2′‐seco‐D‐ribosyl (5′ → 3′)oligonucleotides (= 1′,2′‐seco‐DNA) containing adenine and thymine
1997
Sindbis Virus Nonstructural Protein nsP2 Is Cytotoxic and Inhibits Cellular Transcription
2006
Peptide nucleic acid-targeted mutagenesis of a chromosomal gene in mouse cells
1998
RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform
2010
Two-Helper RNA System for Production of Recombinant Semliki Forest Virus Particles
1999
An α-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain
2003 StandoutNobel
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
Development of Sindbis Viruses Encoding nsP2/GFP Chimeric Proteins and Their Application for Studying nsP2 Functioning
2007
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Molecular Dynamics Simulations of PNA·DNA and PNA·RNA Duplexes in Aqueous Solution
2000
Conformational Heterogeneity in PNA:PNA Duplexes
2010
Host Factors Associated with the Sindbis Virus RNA-Dependent RNA Polymerase: Role for G3BP1 and G3BP2 in Virus Replication
2010 StandoutNobel
Enhancement of Sindbis Virus Self-Replicating RNA Vaccine Potency by Linkage ofMycobacterium tuberculosisHeat Shock Protein 70 Gene to an Antigen Gene
2001 StandoutNobel
Fmoc mediated synthesis of Peptide Nucleic Acids
1995
Chiroptical Molecular Switches
2000 StandoutNobel
Cellular Uptake of Adamantyl Conjugated Peptide Nucleic Acids
1999
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Coordination-Driven Inversion of Handedness in Ligand-Modified PNA
2011
Hairpin-Forming Peptide Nucleic Acid Oligomers
1998
Sweeping antibody as a novel therapeutic antibody modality capable of eliminating soluble antigens from circulation
2016
Thermodynamics of Sequence-Specific Binding of PNA to DNA
2000
Alphavirus-based expression vectors: strategies and applications.
1996 StandoutNobel
Alphaviruses as vectors for gene delivery
1996
Kinetics and mechanism of polyamide ("peptide") nucleic acid binding to duplex DNA.
1995
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
A Field Guide to Foldamers
2001 Standout
NMR Solution Structure of a Peptide Nucleic Acid Complexed with RNA
1994 Science
Organic Chemistry on Solid Supports
1996
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Ionic Effects on the Stability and Conformation of Peptide Nucleic Acid Complexes
1996
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Organische Chemie an fester Phase
1996
Reversible Optical Transcription of Supramolecular Chirality into Molecular Chirality
2004 StandoutScienceNobel
Peptide oligomers for holographic data storage
1996 Nature
Synthesis of 3‘-C- and 4‘-C-Branched Oligodeoxynucleotides and the Development of Locked Nucleic Acid (LNA)
1998
LNA (Locked Nucleic Acids): Synthesis of the adenine, cytosine, guanine, 5-methylcytosine, thymine and uracil bicyclonucleoside monomers, oligomerisation, and unprecedented nucleic acid recognition
1998
Noncytopathic Replication of Venezuelan Equine Encephalitis Virus and Eastern Equine Encephalitis Virus Replicons in Mammalian Cells
2005
Effect of Temperature and Ionic Strength on the Dissociation Kinetics and Lifetime of PNA−DNA Triplexes
2000
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
Synthesis and Characterization of a Native, Oligomeric Form of Recombinant Severe Acute Respiratory Syndrome Coronavirus Spike Glycoprotein
2004 StandoutNobel
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
Warum Pentose‐ und nicht Hexose‐Nucleinsäuren??. Teil V. (Purin‐Purin)‐Basenpaarung in der homo‐DNS‐Reihe: Guanin, Isoguanin, 2,6‐Diaminopurin und Xanthin
1998
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Telomeres in the mouse have large inter-chromosomal variations in the number of T 2 AG 3 repeats
1997
Poly(ADP-Ribose) Polymerase Impairs Early and Long-Term Experimental Stroke Recovery
2002
Peptide Nucleic Acids with a Conformationally Constrained Chiral Cyclohexyl‐Derived Backbone
1997
Observation of a PNA−PNA−PNA Triplex
1997
An Alphavirus Replicon Particle Chimera Derived from Venezuelan Equine Encephalitis and Sindbis Viruses Is a Potent Gene-Based Vaccine Delivery Vector
2003
Noncytopathic Sindbis virus RNA vectors for heterologous gene expression
1998 StandoutNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Enhancement of Sindbis Virus Self-Replicating RNA Vaccine Potency by Linkage of Herpes Simplex Virus Type 1 VP22 Protein to Antigen
2001
Chiral Peptide Nucleic Acids (PNAs): Helix Handedness and DNA Recognition
1999
Enzymatic reaction with unnatural substrates: DNA photolyase ( Escherichia coli ) recognizes and reverses thymine [2+2] dimers in the DNA strand of a DNA/PNA hybrid duplex
1998
Interferon regulatory factor 2 protects mice from lethal viral neuroinvasion
2016 StandoutNobel
A Nucleic Acid Triple Helix Formed by a Peptide Nucleic Acid-DNA Complex
1995 Science
Structure and Function of DNA Photolyase and Cryptochrome Blue-Light Photoreceptors
2003 StandoutNobel
Works of David A. Driver being referenced
PNA hybridizes to complementary oligonucleotides obeying the Watson–Crick hydrogen-bonding rules
1993 StandoutNature
Generation of Retroviral Packaging and Producer Cell Lines for Large-Scale Vector Production and Clinical Application: Improved Safety and High Titer
2000
FcRn Affinity-Pharmacokinetic Relationship of Five Human IgG4 Antibodies Engineered for Improved In Vitro FcRn Binding Properties in Cynomolgus Monkeys
2012
Layered Amplification of Gene Expression with a DNA Gene Delivery System
1995
Alphavirus DNA and particle replicons for vaccines and gene therapy.
2000
Replicon Vectors Derived from Sindbis Virus and Semliki Forest Virus That Establish Persistent Replication in Host Cells
2000
Enhancement of tumor-specific immune response with plasmid DNA replicon vectors.
2000
DNA Immunization against Herpes Simplex Virus: Enhanced Efficacy Using a Sindbis Virus-Based Vector
1998
Stable alphavirus packaging cell lines for Sindbis virus- and Semliki Forest virus-derived vectors
1999
Sindbis virus DNA-based expression vectors: utility for in vitro and in vivo gene transfer
1996
Infection of Human Dendritic Cells by a Sindbis Virus Replicon Vector Is Determined by a Single Amino Acid Substitution in the E2 Glycoprotein
2000