Standout Papers
- ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures (2003)
- A TRP Channel that Senses Cold Stimuli and Menthol (2002)
- TRPA1 mediates spinal antinociception induced by acetaminophen and the cannabinoid Δ9-tetrahydrocannabiorcol (2011)
- A Heat-Sensitive TRP Channel Expressed in Keratinocytes (2002)
- Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide (1999)
Citation Impact
Citing Papers
Cox-dependent fatty acid metabolites cause pain through activation of the irritant receptor TRPA1
2008
TRPA1 acts as a cold sensor in vitro and in vivo
2009
Intracellular Ca 2+ and the phospholipid PIP 2 regulate the taste transduction ion channel TRPM5
2003
TRP Channels as Potential Drug Targets
2017
Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli
2009
Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels
2010 StandoutScienceNobel
Clues to understanding cold sensation: Thermodynamics and electrophysiological analysis of the cold receptor TRPM8
2004
Structure of the cold- and menthol-sensing ion channel TRPM8
2017 Science
A Modular PIP 2 Binding Site as a Determinant of Capsaicin Receptor Sensitivity
2003 StandoutScienceNobel
Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli
2011 StandoutNobel
4-Hydroxynonenal, an endogenous aldehyde, causes pain and neurogenic inflammation through activation of the irritant receptor TRPA1
2007 StandoutNobel
A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
2009
The trp ion channel family
2001
A primer on ankyrin repeat function in TRP channels and beyond
2008
Species differences and molecular determinant of TRPA1 cold sensitivity
2013
Pharmacology of airway afferent nerve activity
2001
Molecular Prerequisites for Diminished Cold Sensitivity in Ground Squirrels and Hamsters
2017
The Nociceptor Ion Channel TRPA1 Is Potentiated and Inactivated by Permeating Calcium Ions
2008
Calcium Plays a Central Role in the Sensitization of TRPV3 Channel to Repetitive Stimulations
2008
Nociceptors: a phylogenetic view
2009
TRPM8-independent Menthol-induced Ca2+ Release from Endoplasmic Reticulum and Golgi
2006
Differential Regulation of TRPV1, TRPV3, and TRPV4 Sensitivity through a Conserved Binding Site on the Ankyrin Repeat Domain
2009
Novel Role of Cold/Menthol-sensitive Transient Receptor Potential Melastatine Family Member 8 (TRPM8) in the Activation of Store-operated Channels in LNCaP Human Prostate Cancer Epithelial Cells
2005
Molecular Basis Determining Inhibition/Activation of Nociceptive Receptor TRPA1 Protein
2014
Lessons from peppers and peppermint: the molecular logic of thermosensation
2003 StandoutNobel
Desensitization of Capsaicin-activated Currents in the Vanilloid Receptor TRPV1 Is Decreased by the Cyclic AMP-dependent Protein Kinase Pathway
2003
TRP Channel Regulates EGFR Signaling in Hair Morphogenesis and Skin Barrier Formation
2010
Reduced Anxiety, Conditioned Fear, and Hippocampal Long-Term Potentiation in Transient Receptor Potential Vanilloid Type 1 Receptor-Deficient Mice
2007
TRPM4 Is a Ca2+-Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization
2002
p38 MAPK Activation by NGF in Primary Sensory Neurons after Inflammation Increases TRPV1 Levels and Maintains Heat Hyperalgesia
2002
Thermodynamics of Heat Activation of Single Capsaicin Ion Channels VR1
2003
Emergence of Functional Sensory Subtypes as Defined by Transient Receptor Potential Channel Expression
2007
Two populations of cold‐sensitive neurons in rat dorsal root ganglia and their modulation by nerve growth factor
2004
Combinatorial Expression of TRPV Channel Proteins Defines Their Sensory Functions and Subcellular Localization in C. elegans Neurons
2002
TRPM2 Ca2+ permeable cation channels: from gene to biological function
2003
TRPV3 and TRPV4 Mediate Warmth-evoked Currents in Primary Mouse Keratinocytes
2004
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
2007 StandoutNatureNobel
Mechanisms of sensory transduction in the skin
2007 Nature
Molecular mechanisms of nociception
2001 StandoutNatureNobel
Cellular Mechanisms of Neurogenic Inflammation
2002
A Large-Conductance Calcium-Selective Mechanotransducer Channel in Mammalian Cochlear Hair Cells
2006
TRPM8 Mechanism of Cold Allodynia after Chronic Nerve Injury
2007
Quantifying and Modeling the Temperature-Dependent Gating of TRP Channels
2012
Voltage is a partial activator of rat thermosensitive TRP channels
2007
Sensitization of TRPA1 by PAR2 contributes to the sensation of inflammatory pain
2007
TRPM8, but not TRPA1, is required for neural and behavioral responses to acute noxious cold temperatures and cold-mimetics in vivo
2010
TRPA1 Mediates Mechanical Currents in the Plasma Membrane of Mouse Sensory Neurons
2010
Transient receptor potential ion channels as participants in thermosensation and thermoregulation
2006
TRPV3 in keratinocytes transmits temperature information to sensory neurons via ATP
2009 StandoutNobel
More than cool: Promiscuous relationships of menthol and other sensory compounds
2006 StandoutNobel
TRP channels and lipids: from Drosophila to mammalian physiology
2006
ThermoTRP channels and beyond: mechanisms of temperature sensation
2003 StandoutNobel
TRPM8 mRNA Is Expressed in a Subset of Cold-Responsive Trigeminal Neurons From Rat
2003
Pore region of TRPV3 ion channel is specifically required for heat activation
2008 StandoutNobel
Opposite thermosensor in fruitfly and mouse
2003 StandoutNatureNobel
TRPA1 is a major oxidant sensor in murine airway sensory neurons
2008
Intact Aδ-fibers up-regulate transient receptor potential A1 and contribute to cold hypersensitivity in neuropathic rats
2008
Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels
2006
Nociceptive Signals Induce Trafficking of TRPA1 to the Plasma Membrane
2009 StandoutNobel
TRP channels in mechanosensation: direct or indirect activation?
2007
Zebrafish TRPA1 Channels Are Required for Chemosensation But Not for Thermosensation or Mechanosensory Hair Cell Function
2008 StandoutNobel
The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation
2009
Cold transduction in rat trigeminal ganglia neurons in vitro
2003
Production of dissociated sensory neuron cultures and considerations for their use in studying neuronal function and plasticity
2007
Expression and Characterization of Human Transient Receptor Potential Melastatin 3 (hTRPM3)
2003
Cough and airway disease: The role of ion channels
2017
Homologous and heterologous desensitization of capsaicin and mustard oil responses utilize different cellular pathways in nociceptors
2007
Heat-evoked Activation of TRPV4 Channels in a HEK293 Cell Expression System and in Native Mouse Aorta Endothelial Cells
2002
An Ion Channel Essential for Sensing Chemical Damage
2007 StandoutNobel
The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels
2004 Nature
Signal-dependent Hydrolysis of Phosphatidylinositol 4,5-Bisphosphate without Activation of Phospholipase C
2011
Prostaglandin-Induced Activation of Nociceptive Neurons via Direct Interaction with Transient Receptor Potential A1 (TRPA1)
2007
Structure–functional intimacies of transient receptor potential channels
2009
2-Aminoethoxydiphenyl Borate Activates and Sensitizes the Heat-Gated Ion Channel TRPV3
2004
TRPA1 Is Differentially Modulated by the Amphipathic Molecules Trinitrophenol and Chlorpromazine
2007
Evolution of Thermal Response Properties in a Cold-Activated TRP Channel
2009 StandoutNobel
Transient receptor potential channels: targeting pain at the source
2008 StandoutNobel
Thermoreceptors and thermosensitive afferents
2009
painless, a Drosophila Gene Essential for Nociception
2003
Distinct expression of TRPM8, TRPA1, and TRPV1 mRNAs in rat primary afferent neurons with aδ/c‐fibers and colocalization with trk receptors
2005
Visualizing Cold Spots: TRPM8-Expressing Sensory Neurons and Their Projections
2008 StandoutNobel
Thymol and related alkyl phenols activate the hTRPA1 channel
2008
Nociceptors Lacking TRPV1 and TRPV2 Have Normal Heat Responses
2004
Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels
2008 StandoutNobel
TRPM2 activation by cyclic ADP‐ribose at body temperature is involved in insulin secretion
2006
The high threshold mechanotransducer: A status report
2005
TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology
2012
TRPM8 voltage sensor mutants reveal a mechanism for integrating thermal and chemical stimuli
2007
Functional Control of Cold- and Menthol-Sensitive TRPM8 Ion Channels by Phosphatidylinositol 4,5-Bisphosphate
2005
Phosphoinositide Sensitivity of Ion Channels, a Functional Perspective
2012
Variable Threshold of Trigeminal Cold-Thermosensitive Neurons Is Determined by a Balance between TRPM8 and Kv1 Potassium Channels
2009
Heat Sensitization in Skin and Muscle Nociceptors Expressing Distinct Combinations of TRPV1 and TRPV2 Protein
2007
From chills to chilis: mechanisms for thermosensation and chemesthesis via thermoTRPs
2007 StandoutNobel
Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild‐type and TRPV1–/– mice
2003
TRPV channels as temperature sensors
2003
TRPV1 Is Activated by Both Acidic and Basic pH
2009 StandoutNobel
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
2006 StandoutNobel
Single Residues in the Outer Pore of TRPV1 and TRPV3 Have Temperature-Dependent Conformations
2013 StandoutNobel
Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels
2008
Neuronal TRP channels: thermometers, pathfinders and life-savers
2008
Mechanically Activated Ion Channels
2015 StandoutNobel
Agonist Recognition Sites in the Cytosolic Tails of Vanilloid Receptor 1
2002
The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis
2004
Molecular mechanisms of mechanotransduction in mammalian sensory neurons
2011
Rapid Temperature Jump by Infrared Diode Laser Irradiation for Patch-Clamp Studies
2009
Nociceptor and Hair Cell Transducer Properties of TRPA1, a Channel for Pain and Hearing
2005
The Transmembrane Segment S6 Determines Cation versus Anion Selectivity of TRPM2 and TRPM8
2007
Phosphoinositides regulate ion channels
2014
Thermo-TRP Channels: Biophysics of Polymodal Receptors
2010
Distinct Roles of TRP Channels in Auditory Transduction and Amplification in Drosophila
2013
The Pungency of Garlic: Activation of TRPA1 and TRPV1 in Response to Allicin
2005 StandoutNobel
Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors
2010
International Union of Pharmacology. XLIII. Compendium of Voltage-Gated Ion Channels: Transient Receptor Potential Channels
2003 StandoutNobel
Characterization of the mouse cold‐menthol receptor TRPM8 and vanilloid receptor type‐1 VR1 using a fluorometric imaging plate reader (FLIPR) assay
2004
TRP channels as cellular sensors
2003 StandoutNature
Gating of TRP channels: a voltage connection?
2005
Bimodal Action of Menthol on the Transient Receptor Potential Channel TRPA1
2007
The mechano‐activated K+ channels TRAAK and TREK‐1 control both warm and cold perception
2009
A Cell-Penetrating Scorpion Toxin Enables Mode-Specific Modulation of TRPA1 and Pain
2019 StandoutNobel
TRPA1 Contributes to Cold Hypersensitivity
2010 StandoutNobel
Numbing the Senses: Role of TRPA1 in Mechanical and Cold Sensation
2006
ThermoTRP channels and cold sensing: what are they really up to?
2005
TRPM8 Is Required for Cold Sensation in Mice
2007 StandoutNobel
Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures
2007 Nature
Pyrexia is a new thermal transient receptor potential channel endowing tolerance to high temperatures in Drosophila melanogaster
2005
Diversity in the Neural Circuitry of Cold Sensing Revealed by Genetic Axonal Labeling of Transient Receptor Potential Melastatin 8 Neurons
2007
Induction of vanilloid receptor channel activity by protein kinase C
2000 Nature
Molecular basis of infrared detection by snakes
2010 StandoutNatureNobel
Mrgprd Enhances Excitability in Specific Populations of Cutaneous Murine Polymodal Nociceptors
2009
Extracellular Cations Sensitize and Gate Capsaicin Receptor TRPV1 Modulating Pain Signaling
2005
Camphor Activates and Strongly Desensitizes the Transient Receptor Potential Vanilloid Subtype 1 Channel in a Vanilloid-Independent Mechanism
2005
Functional expression of transient receptor potential vanilloid 3 (TRPV3) in corneal epithelial cells: Involvement in thermosensation and wound healing
2009
PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain
2005
Altered Thermal Selection Behavior in Mice Lacking Transient Receptor Potential Vanilloid 4
2005
Bradykinin and nerve growth factor release the capsaicin receptor from PtdIns(4,5)P2-mediated inhibition
2001 StandoutNatureNobel
The TRPV3 mutation associated with the hairless phenotype in rodents is constitutively active
2007
Temperature-dependent activation of recombinant rat vanilloid VR1 receptors expressed in HEK293 cells by capsaicin and anandamide
2001
Transient Receptor Potential Channels in Sensory Neurons Are Targets of the Antimycotic Agent Clotrimazole
2008
Molecular and Functional Characterization of the Melastatin-related Cation Channel TRPM3
2003
Activation of TRPA1 by Farnesyl Thiosalicylic Acid
2008
A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic
2008
cAMP-Dependent Protein Kinase Regulates Desensitization of the Capsaicin Receptor (VR1) by Direct Phosphorylation
2002
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
Intracellular alkalization causes pain sensation through activation of TRPA1 in mice
2008
Phosphoinositide regulation of TRPV1 revisited
2015
Contribution of vanilloid receptors to the overt nociception induced by B2 kinin receptor activation in mice
2004
TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action
2016 StandoutNatureNobel
TRPM5 Is a Voltage-Modulated and Ca2+-Activated Monovalent Selective Cation Channel
2003
Transient receptor potential TRPA1 channel desensitization in sensory neurons is agonist dependent and regulated by TRPV1‐directed internalization
2007
Irritating channels: the case of TRPA1
2010
ThermoTRP channels as modular proteins with allosteric gating
2007
Analgesia Mediated by the TRPM8 Cold Receptor in Chronic Neuropathic Pain
2006
AMTB, a TRPM8 channel blocker: evidence in rats for activity in overactive bladder and painful bladder syndrome
2008
Transient receptor potential A1 mediates an osmotically activated ion channel
2008
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Transient receptor potential V2 expressed in sensory neurons is activated by probenecid
2007
Voltage‐ and time‐dependent properties of the recombinant rat vanilloid receptor (rVR1)
2000
Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels
2003 Nature
The epithelial calcium channels, TRPV5 & TRPV6: from identification towards regulation
2003
Expressing TrkC from the TrkA locus causes a subset of dorsal root ganglia neurons to switch fate
2004 StandoutNobel
Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor
2000 Standout
Direct recording and molecular identification of the calcium channel of primary cilia
2013 Nature
TRP channels: An overview
2005
Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin
2004 StandoutNobel
TRPA1 Channels Mediate Cold Temperature Sensing in Mammalian Vagal Sensory Neurons: Pharmacological and Genetic Evidence
2008
Biphasic Currents Evoked by Chemical or Thermal Activation of the Heat-gated Ion Channel, TRPV3
2005
Noxious heat receptors present in cold-sensory cells in rats
2004
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
2002 StandoutNobel
The menthol receptor TRPM8 is the principal detector of environmental cold
2007 StandoutNatureNobel
Multiple types of sensory neurons respond to irritating volatile organic compounds (VOCs): Calcium fluorimetry of trigeminal ganglion neurons
2005
TRPA1 Contributes to Cold, Mechanical, and Chemical Nociception but Is Not Essential for Hair-Cell Transduction
2006
Overexpressed Transient Receptor Potential Vanilloid 3 Ion Channels in Skin Keratinocytes Modulate Pain Sensitivity via Prostaglandin E2
2008
High-throughput random mutagenesis screen reveals TRPM8 residues specifically required for activation by menthol
2006 StandoutNobel
The TRP Channels, a Remarkably Functional Family
2002
Anandamide-Evoked Activation of Vanilloid Receptor 1 Contributes to the Development of Bladder Hyperreflexia and Nociceptive Transmission to Spinal Dorsal Horn Neurons in Cystitis
2004
Warm Temperature-sensitive Transient Receptor Potential Vanilloid 4 (TRPV4) Plays an Essential Role in Thermal Hyperalgesia
2004
TRPM8 protein localization in trigeminal ganglion and taste papillae
2005
A possible unifying principle for mechanosensation
2005 Nature
Sensing with TRP channels
2005
Heat generates oxidized linoleic acid metabolites that activate TRPV1 and produce pain in rodents
2010
TRPA1 is a candidate for the mechanosensitive transduction channel of vertebrate hair cells
2004 Nature
A novel type of cold‐sensitive neuron in rat dorsal root ganglia with rapid adaptation to cooling stimuli
2006
TRPA1 Mediates Mechanical Sensitization in Nociceptors during Inflammation
2012
Critical role of the pore domain in the cold response of TRPM8 channels identified by ortholog functional comparison
2018
Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
2004 StandoutNatureNobel
Thermosensory and Nonthermosensory Isoforms of Drosophila melanogaster TRPA1 Reveal Heat-Sensor Domains of a ThermoTRP Channel
2012
Temperature-induced opening of TRPV1 ion channel is stabilized by the pore domain
2010 StandoutNobel
Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro
2009
Single‐channel properties of native and cloned rat vanilloid receptors
2002
Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six
2014 StandoutNobel
Homo- and heteromeric assembly of TRP channel subunits
2005
Caenorhabditis elegans TRPA-1 functions in mechanosensation
2007 StandoutNobel
A cold‐ and menthol‐activated current in rat dorsal root ganglion neurones: properties and role in cold transduction
2002
TRPA1 Mediates the Inflammatory Actions of Environmental Irritants and Proalgesic Agents
2006 StandoutNobel
Nociceptors—Noxious Stimulus Detectors
2007
A Yeast Genetic Screen Reveals a Critical Role for the Pore Helix Domain in TRP Channel Gating
2008 StandoutNobel
Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats
2006
Inorganic Polyphosphate Modulates TRPM8 Channels
2009
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
2000 StandoutNature
Ethanol elicits and potentiates nociceptor responses via the vanilloid receptor-1
2002
Hypotonicity Induces TRPV4-Mediated Nociception in Rat
2003
The Super-Cooling Agent Icilin Reveals a Mechanism of Coincidence Detection by a Temperature-Sensitive TRP Channel
2004 StandoutNobel
TRPV1 Acts as Proton Channel to Induce Acidification in Nociceptive Neurons
2004
Thermoregulation: Channels that Are Cool to the Core
2007
Agonist-Induced Changes in Ca2+ Permeation through the Nociceptor Cation Channel TRPA1
2010
Identification of Species-specific Determinants of the Action of the Antagonist Capsazepine and the Agonist PPAHV on TRPV1
2004
Nitric oxide function in the skin
2004
Response of Drosophila to Wasabi Is Mediated by painless, the Fly Homolog of Mammalian TRPA1/ANKTM1
2006
The pore properties of human nociceptor channel TRPA1 evaluated in single channel recordings
2010
Structure and gating mechanism of the transient receptor potential channel TRPV3
2018
Warm Temperatures Activate TRPV4 in Mouse 308 Keratinocytes
2003
The TRPV1/2/3 activator 2-aminoethoxydiphenyl borate sensitizes native nociceptive neurons to heat in wildtype but not TRPV1 deficient mice
2005
TRPV1 Channels Mediate Long-Term Depression at Synapses on Hippocampal Interneurons
2008
Gating of Transient Receptor Potential Melastatin 8 (TRPM8) Channels Activated by Cold and Chemical Agonists in Planar Lipid Bilayers
2010
A Genetic Program Promotes C. elegans Longevity at Cold Temperatures via a Thermosensitive TRP Channel
2013
Phospholipase C and protein kinase A mediate bradykinin sensitization of TRPA1: a molecular mechanism of inflammatory pain
2008
The TRPV4 Channel Contributes to Intercellular Junction Formation in Keratinocytes
2010
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
TRPV3 regulates nitric oxide synthase-independent nitric oxide synthesis in the skin
2011 StandoutNobel
A Hot-Sensing Cold Receptor: C-Terminal Domain Determines Thermosensation in Transient Receptor Potential Channels
2006
TRPA1 Modulates Mechanotransduction in Cutaneous Sensory Neurons
2009
TRPV3 is a calcium-permeable temperature-sensitive cation channel
2002 Nature
N-Glycosylation of TRPM8 Ion Channels Modulates Temperature Sensitivity of Cold Thermoreceptor Neurons
2012
TRPV1 and TRPA1 Mediate Peripheral Nitric Oxide-Induced Nociception in Mice
2009 StandoutNobel
From Foe to Friend: Using Animal Toxins to Investigate Ion Channel Function
2014
The Met268Pro Mutation of Mouse TRPA1 Changes the Effect of Caffeine from Activation to Suppression
2010
Contribution of TRPM8 Channels to Cold Transduction in Primary Sensory Neurons and Peripheral Nerve Terminals
2006
Action potential initiation in the peripheral terminals of cold‐sensitive neurones innervating the guinea‐pig cornea
2009
Transient Receptor Potential Channel A1 Is Directly Gated by Calcium Ions
2007
Ion channels involved in cold detection in mammals: TRP and non-TRP mechanisms
2009
Monoterpenoid agonists of TRPV3
2007
Protein kinase C phosphorylation sensitizes but does not activate the capsaicin receptor transient receptor potential vanilloid 1 (TRPV1)
2003
Channeling pain
2006 StandoutNobel
Pore Dilation Occurs in TRPA1 but Not in TRPM8 Channels
2009
HC-030031, a TRPA1 Selective Antagonist, Attenuates Inflammatory- and Neuropathy-Induced Mechanical Hypersensitivity
2008
Anandamide Excites Central Terminals of Dorsal Root Ganglion Neurons via Vanilloid Receptor-1 Activation
2001
TRP Channel Proteins and Signal Transduction
2002
Dynamic changes in the TRPA1 selectivity filter lead to progressive but reversible pore dilation
2010
A Role of TRPA1 in Mechanical Hyperalgesia is Revealed by Pharmacological Inhibition
2007 StandoutNobel
Cold sensitivity of recombinant TRPA1 channels
2007
Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler ( Va ) mice
2002
Attenuated Cold Sensitivity in TRPM8 Null Mice
2007
Evolution of thermoTRP ion channel homologs in vertebrates
2006
Modulation of Thermoreceptor TRPM8 by Cooling Compounds
2012
TRPV2 Is a Component of Osmotically Sensitive Cation Channels in Murine Aortic Myocytes
2003
PERMEATION AND SELECTIVITY OF TRP CHANNELS
2005
Molecular and Cellular Limits to Somatosensory Specificity
2008
The TRP Superfamily of Cation Channels
2005
Pungent products from garlic activate the sensory ion channel TRPA1
2005 StandoutNobel
Species-Specific Pharmacology of Trichloro(Sulfanyl)ethyl Benzamides as Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists
2007
TRPV1 Channels Are Intrinsically Heat Sensitive and Negatively Regulated by Phosphoinositide Lipids
2013 StandoutNobel
Development of TRPM8 Antagonists to Treat Chronic Pain and Migraine
2017
Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor
2000 StandoutScienceNobel
Molecular Background of Leak K+Currents: Two-Pore Domain Potassium Channels
2010
Structure–function relationship of the TRP channel superfamily
2006
Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats
2006
TRP Channels and Pain
2013 StandoutNobel
NGF Up-regulates TRPA1: Implications for Orofacial Pain
2007
Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl
2014
Detection of Cold Pain, Cold Allodynia and Cold Hyperalgesia in Freely Behaving Rats
2005
Burning Cold: Involvement of TRPA1 in Noxious Cold Sensation
2009
A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels
2011
Mechanism for phosphoinositide selectivity and activation of TRPV1 ion channels
2015
Impaired Thermosensation in Mice Lacking TRPV3, a Heat and Camphor Sensor in the Skin
2005 StandoutScienceNobel
Breathtaking TRP Channels: TRPA1 and TRPV1 in Airway Chemosensation and Reflex Control
2008
How Cold is It? TRPM8 and TRPA1 in the Molecular Logic of Cold Sensation
2005
Design and Optimization of Benzimidazole-Containing Transient Receptor Potential Melastatin 8 (TRPM8) Antagonists
2010
Direct activation of the ion channel TRPA1 by Ca2+
2007
TRPM8 acute desensitization is mediated by calmodulin and requires PIP2: distinction from tachyphylaxis
2011
Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4
2009 StandoutNobel
Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties
2000
TRPA1 and Cold Transduction: An Unresolved Issue?
2009
TRPA1 mediates formalin-induced pain
2007 StandoutNobel
AN INTRODUCTION TO TRP CHANNELS
2005 Standout
Oxaliplatin‐induced cold hypersensitivity is due to remodelling of ion channel expression in nociceptors
2011
The Vanilloid Receptor: A Molecular Gateway to the Pain Pathway
2001 StandoutNobel
Caffeine activates mouse TRPA1 channels but suppresses human TRPA1 channels
2008
Direct activation of capsaicin receptors by products of lipoxygenases: Endogenous capsaicin-like substances
2000
TRP ION CHANNELS AND TEMPERATURE SENSATION
2006 StandoutNobel
Inhibition of transient receptor potential melastatin 8 alleviates airway inflammation and remodeling in a murine model of asthma with cold air stimulus
2018
Cutaneous Nociception Evoked by 15-delta PGJ2 via Activation of Ion Channel TRPA1
2008
TRPA1: A Gatekeeper for Inflammation
2012
Evidence that TRPM8 Is an Androgen-Dependent Ca2+ Channel Required for the Survival of Prostate Cancer Cells
2004
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
2019 Science
TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury
2005
Heat-Evoked Activation of the Ion Channel, TRPV4
2002
TRP Channels
2007 Standout
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
Ca2+ Regulation of TRP Ion Channels
2018
Polymodal Ligand Sensitivity of TRPA1 and Its Modes of Interactions
2009
Works of David A. Andersson being referenced
ANKTM1, a TRP-like Channel Expressed in Nociceptive Neurons, Is Activated by Cold Temperatures
2003 StandoutNobel
Streptozotocin Stimulates the Ion Channel TRPA1 Directly
2015
Transient Receptor Potential A1 Is a Sensory Receptor for Multiple Products of Oxidative Stress
2008
TRPM8 Activation by Menthol, Icilin, and Cold Is Differentially Modulated by Intracellular pH
2004
Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide
1999 StandoutNatureNobel
Modulation of the Cold-Activated Channel TRPM8 by Lysophospholipids and Polyunsaturated Fatty Acids
2007
TRPV1
2014
A TRP Channel that Senses Cold Stimuli and Menthol
2002 StandoutNobel
Δ9-Tetrahydrocannabinol and Cannabinol Activate Capsaicin-Sensitive Sensory Nerves via a CB1 and CB2 Cannabinoid Receptor-Independent Mechanism
2002
G protein βγ subunits inhibit TRPM3 ion channels in sensory neurons
2017
The Roles of iPLA2, TRPM8 and TRPA1 in Chemically Induced Cold Hypersensitivity
2010
A Heat-Sensitive TRP Channel Expressed in Keratinocytes
2002 StandoutScienceNobel