Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
Selective modification of apoB-100 in the oxidation of low density lipoproteins by myeloperoxidase in vitro
1999
Comparison between copper-mediated and hypochlorite-mediated modifications of human low density lipoproteins evaluated by protein carbonyl formation
1997
Detection, identification, and quantification of oxidative protein modifications
2019
Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions
2000
Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Converts Low Density Lipoprotein Cholesterol into a Family of Chlorinated Sterols
1996
Correlation between intima-to-media ratio, apolipoprotein B-100, myeloperoxidase, and hypochlorite-oxidized proteins in human atherosclerosis
2001
Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
1999
Exercise-Induced Oxidative Stress: Cellular Mechanisms and Impact on Muscle Force Production
2008 Standout
Biomarkers of myeloperoxidase-derived hypochlorous acid
2000
The role of vitamin E in atherosclerosis
2003
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Cell signaling by reactive nitrogen and oxygen species in atherosclerosis
2000
Growing Significance of Myeloperoxidase in Non-infectious Diseases
2002
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Oxidation Regulates the Inflammatory Properties of the Murine S100 Protein S100A8
1999
SHIP Modulates Immune Receptor Responses by Regulating Membrane Association of Btk
1998
Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
2007 Standout
Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes
2001
NADPH oxidase-derived oxidant stress is critical for neutrophil cytotoxicity during endotoxemia
2004
Estrogen receptor α is a major mediator of 17β-estradiol’s atheroprotective effects on lesion size in Apoe–/– mice
2001 StandoutNobel
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
p-Hydroxyphenylacetaldehyde, the Major Product of l-Tyrosine Oxidation by the Myeloperoxidase-H2O2-Chloride System of Phagocytes, Covalently Modifies ε-Amino Groups of Protein Lysine Residues
1997
Class B Scavenger Receptors CD36 and SR-BI Are Receptors for Hypochlorite-modified Low Density Lipoprotein
2003
Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging
2012 Standout
Coenzyme Q10 supplementation inhibits aortic lipid oxidation but fails to attenuate intimal thickening in balloon-injured New Zealand white rabbits
2003
Comparison of low-density lipoprotein modification by myeloperoxidase-derived hypochlorous andhypobromous acids
2001
Identification of a Novel Family of Oxidized Phospholipids That Serve as Ligands for the Macrophage Scavenger Receptor CD36
2002
Oxysterols and atherosclerosis
1999
Stable markers of oxidant damage to proteins and their application in the study of human disease
1999
A Fluorescent Probe for the Detection of Myeloperoxidase Activity in Atherosclerosis-Associated Macrophages
2007
Modification of proteins and lipids by myeloperoxidase
1999
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
1997 Standout
An improved method for the sensitive monitoring of low density lipoprotein modification by myeloperoxidase
2001
Myeloperoxidase Is Critically Involved in the Induction of Organ Damage after Renal Ischemia Reperfusion
2007
Anti-atherogenic effect of coenzyme Q10 in apolipoprotein E gene knockout mice
2000
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Biological reactivity and biomarkers of the neutrophil oxidant, hypochlorous acid
2002
A specific and sensitive method for detection of hypochlorous acid for the imaging of microbe-induced HOCl production
2011
Hypochlorous Acid Oxygenates the Cysteine Switch Domain of Pro-matrilysin (MMP-7)
2001
Myeloperoxidase
1999
Patterns of oxidized epitopes, but not NF-κB expression, change during atherogenesis in WHHL rabbits
2002
Human Phagocytes Employ the Myeloperoxidase-Hydrogen Peroxide System to Synthesize Dityrosine, Trityrosine, Pulcherosine, and Isodityrosine by a Tyrosyl Radical-dependent Pathway
1996
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
The Nitric Oxide Congener Nitrite Inhibits Myeloperoxidase/H2O2/ Cl−-mediated Modification of Low Density Lipoprotein
2001
Hypochlorite-modified Low Density Lipoprotein Inhibits Nitric Oxide Synthesis in Endothelial Cells via an Intracellular Dislocalization of Endothelial Nitric-oxide Synthase
2001
Inhibition of hypochlorous acid-induced oxidative reactions by nitrite: is nitrite an antioxidant?
2003
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation.
1997
Myeloperoxidase in kidney disease
2003
Lysine Residues Direct the Chlorination of Tyrosines in YXXK Motifs of Apolipoprotein A-I When Hypochlorous Acid Oxidizes High Density Lipoprotein
2004
Myeloperoxidase binds to low‐density lipoprotein: potential implications for atherosclerosis
2000
Hypochlorite-Modified (Lipo)Proteins Are Present in Rabbit Lesions in Response to Dietary Cholesterol
2001
Myeloperoxidase-generated oxidants and atherosclerosis
2000
Oxidation of Free Fatty Acids in Low Density Lipoprotein by 15-Lipoxygenase Stimulates Nonenzymic, α-Tocopherol-mediated Peroxidation of Cholesteryl Esters
1997
Oxidized low-density lipoprotein inhibits hepatitis C virus cell entry in human hepatoma cells
2006 StandoutNobel
Increased atherosclerosis in myeloperoxidase-deficient mice
2001
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Relative reactivity of lysine and other peptide-bound amino acids to oxidation by hypochlorite
2000
Inflammation in atherosclerosis
2002 StandoutNature
Myeloperoxidase
2000
Protein carbonyl groups as biomarkers of oxidative stress
2003 Standout
Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species
2000
Inhibition of Oxidation of Low-Density Lipoprotein by a Novel Antioxidant, BO-653, Prepared by Theoretical Design
1997
Nitric Oxide Modulates the Catalytic Activity of Myeloperoxidase
2000
Reactive oxygen species in cardiovascular disease
2011
The Oxidation of Lipoproteins by Monocytes-Macrophages
1999
Contributions of Myeloperoxidase to Proinflammatory Events: More Than an Antimicrobial System
2001
Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
2008 Standout
Ablation of the Inflammatory Enzyme Myeloperoxidase Mitigates Features of Parkinson's Disease in Mice
2005
Autoantibodies against modified low-density lipoproteins in coronary artery disease
2003
Transmembrane crosstalk between the extracellular matrix and the cytoskeleton
2001 Standout
Hypochlorite-modified low-density lipoprotein stimulates human polymorphonuclear leukocytes for enhanced production of reactive oxygen metabolites, enzyme secretion, and adhesion to endothelial cells
1998
Atherosclerosis
2000 StandoutNature
Hypochlorite-oxidized low-density lipoprotein upregulates CD36 and PPARγ mRNA expression and modulates SR-BI gene expression in murine macrophages
2005
Does an acidic pH explain why low density lipoprotein is oxidised in atherosclerotic lesions?
1997
Reactions of Hypochlorous Acid with Tyrosine and Peptidyl-tyrosyl Residues Give Dichlorinated and Aldehydic Products in Addition to 3-Chlorotyrosine
2000
Human neutrophils employ chlorine gas as an oxidant during phagocytosis.
1996
Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions
2000
Recent progress in the development of near-infrared fluorescent probes for bioimaging applications
2013 Standout
Combined Serum Paraoxonase Knockout/Apolipoprotein E Knockout Mice Exhibit Increased Lipoprotein Oxidation and Atherosclerosis
2000 Standout
QUANTIFICATION AND SIGNIFICANCE OF PROTEIN OXIDATION IN BIOLOGICAL SAMPLES*
2000
Atherosclerosis
2001 Standout
Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase.
1998 Standout
Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
2011 StandoutNature
Hydrogen sulphide: A novel physiological inhibitor of LDL atherogenic modification by HOCl
2007
Human neutrophils employ the myeloperoxidase/hydrogen peroxide/chloride system to oxidatively damage apolipoprotein A‐I
2001
Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humans
1999
α‐Tocopherol does not inhibit hypochlorite‐induced oxidation of apolipoprotein B‐100 of low‐density lipoprotein
1997
Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis
1998
Naked-eye visible and fluorometric dual-signaling chemodosimeter for hypochlorous acid based on water-soluble p-methoxyphenol derivative
2011
Human Neutrophils Oxidize Low-Density Lipoprotein by a Hypochlorous Acid- Dependent Mechanism: The Role of Vitamin C
2002
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Oxidative Stress and Endothelial Nitric Oxide Bioactivity
2003
Physiological Implications of Hydrogen Sulfide: A Whiff Exploration That Blossomed
2012 Standout
Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein
2000
Reciprocal Relationships Between Insulin Resistance and Endothelial Dysfunction
2006 Standout
Hypochlorite-induced oxidation of proteins in plasma: formation of chloramines and nitrogen-centred radicals and their role in protein fragmentation
1999
Dietary Cosupplementation With Vitamin E and Coenzyme Q 10 Inhibits Atherosclerosis in Apolipoprotein E Gene Knockout Mice
2001
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Site-Specific Antiatherogenic Effect of Probucol in Apolipoprotein E–Deficient Mice
2000
Detection of HOCl-mediated protein oxidation products in the extracellular matrix of human atherosclerotic plaques
2003
A Single Nanoprobe for Ratiometric Imaging and Biosensing of Hypochlorite and Glutathione in Live Cells Using Surface-Enhanced Raman Scattering
2016
Nitric oxide and the immune response
2001 Standout
Biochemistry and pathology of radical-mediated protein oxidation
1997
Secondary radicals derived from chloramines of apolipoprotein B-100 contribute to HOCl-induced lipid peroxidation of low-density lipoproteins
1999
Enantioselective Synthesis of Di- and Tri-Arylated All-Carbon Quaternary Stereocenters via Copper-Catalyzed Allylic Arylations with Organolithium Compounds
2016 StandoutNobel
Fragmentation of extracellular matrix by hypochlorous acid
2003
Tocopherol‐mediated peroxidation of lipoproteins: implications for vitamin E as a potential antiatherogenic supplement
1999
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Structural modification strategies for the rational design of red/NIR region BODIPYs
2014 Standout
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
2009 StandoutNobel
Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo
2013 Standout
Direct Detection and Quantification of Transition Metal Ions in Human Atherosclerotic Plaques: Evidence for the Presence of Elevated Levels of Iron and Copper
2004
Mass Spectrometric Quantification of Markers for Protein Oxidation by Tyrosyl Radical, Copper, and Hydroxyl Radical in Low Density Lipoprotein Isolated from Human Atherosclerotic Plaques
1997
Time-dependent changes to lipids and antioxidants in plasma and aortas of apolipoprotein E knockout mice
1999
Vitamin E Oxidation in Human Atherosclerotic Lesions
2002
Modification of Type III VLDL, Their Remnants, and VLDL From ApoE-Knockout Mice by p -Hydroxyphenylacetaldehyde, a Product of Myeloperoxidase Activity, Causes Marked Cholesteryl Ester Accumulation in Macrophages
1999
Inflammation and Atherosclerosis
2002 Standout
Oxidation of LDL by Myeloperoxidase and Reactive Nitrogen Species
2000
Immunological evidence for hypochlorite-modified proteins in human kidney.
1997
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Small-Molecule Labeling of Live Cell Surfaces for Three-Dimensional Super-Resolution Microscopy
2014 StandoutNobel
Evidence for roles of radicals in protein oxidation in advanced human atherosclerotic plaque
1998
Glutathione-Related Antioxidant Defenses in Human Atherosclerotic Plaques
1998
Science and technology for water purification in the coming decades
2008 StandoutNature
SH2-Containing Inositol 5′-Phosphatase SHIP2 Associates with the p130CasAdapter Protein and Regulates Cellular Adhesion and Spreading
2001
Hypochlorite-Modified LDL: Chemotactic Potential and Chemokine Induction in Human Monocytes
1998
A BODIPY fluorescent probe with selective response for hypochlorous acid and its application in cell imaging
2013
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
A Dual Role for Src Homology 2 Domain–Containing Inositol-5-Phosphatase (Ship) in Immunity
2000
The Halogen Bond
2016 Standout
Inhibition of hypochlorous acid-induced cellular toxicity by nitrite
2002
Coexistence of Oxidized Lipids and α-Tocopherol in All Lipoprotein Density Fractions Isolated From Advanced Human Atherosclerotic Plaques
1999
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport
2004
Kinetic Analysis of the Reactions of Hypobromous Acid with Protein Components: Implications for Cellular Damage and Use of 3-Bromotyrosine as a Marker of Oxidative Stress
2004
Interactions Between Nitric Oxide and Lipid Oxidation Pathways
2001
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
Vitamin E Supplementation and Cardiovascular Events in High-Risk Patients
2000 Standout
Oxidation of LDL by recombinant human 15-lipoxygenase: evidence for alpha-tocopherol-dependent oxidation of esterified core and surface lipids
1996
Myeloperoxidase: friend and foe
2005 Standout
Works of Dave Flowers being referenced
Presence of hypochlorite-modified proteins in human atherosclerotic lesions.
1996
The Human SHIP Gene Is Differentially Expressed in Cell Lineages of the Bone Marrow and Blood
1997