Citation Impact
Citing Papers
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
2009
Systematic, RNA-Interference-Mediated Identification of mus-101 Modifier Genes in Caenorhabditis elegans
2005
Rhizobium induces DNA damage in Caenorhabditis elegans intestinal cells
2019 StandoutNobel
Feedback control of regulatory T cell homeostasis by dendritic cells in vivo
2009
miR-15 and miR-16 induce apoptosis by targeting BCL2
2005 Standout
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
Identification of a SUMO-binding motif that recognizes SUMO-modified proteins
2004
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Specification of SUMO1- and SUMO2-interacting Motifs
2006
Proteins with two SUMO-like domains in chromatin-associated complexes: The RENi (Rad60-Esc2-NIP45) family
2005
Human MicroRNA Targets
2004 Standout
Modification of Drosophila p53 by SUMO Modulates Its Transactivation and Pro-apoptotic Functions
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation
2005
PIAS proteins: pleiotropic interactors associated with SUMO
2009
Serum response factor is modulated by the SUMO-1 conjugation system
2003
Transforming Growth Factor-β-mediated Signaling via the p38 MAP Kinase Pathway Activates Smad-dependent Transcription through SUMO-1 Modification of Smad4
2003
The lesswright mutation activates Rel-related proteins, leading to overproduction of larval hemocytes in Drosophila melanogaster
2005
Transcriptional regulation by p53: one protein, many possibilities
2006
Topors acts as a SUMO‐1 E3 ligase for p53 in vitro and in vivo
2005
How the ubiquitin–proteasome system controls transcription
2003
Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation
2007
Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
2011 StandoutNobel
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Features of the dendritic cell lineage
2010 StandoutNobel
The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition
2010 Standout
Ubiquitin-Proteasome-mediated Degradation of Id1 Is Modulated by MyoD
2004 StandoutNobel
The Polycomb Protein Pc2 Is a SUMO E3
2003
Regulation of gene-activation pathways by PIAS proteins in the immune system
2005
Opposed Regulation of Corepressor CtBP by SUMOylation and PDZ Binding
2003
Smad transcription factors
2005 Standout
A Large Intergenic Noncoding RNA Induced by p53 Mediates Global Gene Repression in the p53 Response
2010 Standout
Myc pathways provoking cell suicide and cancer
2003
Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain
2002 Standout
p53 in neuronal apoptosis
2005
E4F1 Is an Atypical Ubiquitin Ligase that Modulates p53 Effector Functions Independently of Degradation
2006
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
2005 StandoutNature
Sumoylation is involved in beta-catenin-dependent activation of Tcf-4
2003
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
2009 Nature
The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
2010
Regulation of SUMOylation by Reversible Oxidation of SUMO Conjugating Enzymes
2006
The impact of microRNAs on protein output
2008 StandoutNature
SUMO Modification of STAT1 and Its Role in PIAS-mediated Inhibition of Gene Activation
2003
DC subsets in positive and negative regulation of immunity
2010
Characterization of a Family of Nucleolar SUMO-specific Proteases with Preference for SUMO-2 or SUMO-3
2006
PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein
2006
PIASx Is a MEF2 SUMO E3 Ligase That Promotes Postsynaptic Dendritic Morphogenesis
2007
Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas
2010 StandoutNobel
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
2004 StandoutNobel
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation
2007
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Identification of a Multifunctional Binding Site on Ubc9p Required for Smt3p Conjugation
2002
Three-dimensional reconstruction of the human central sulcus reveals a morphological correlate of the hand area
1998
Regulation of Smad4 Sumoylation and Transforming Growth Factor-β Signaling by Protein Inhibitor of Activated STAT1
2004
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
2006 Standout
Regulation and Function of SUMO Modification
2004
The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type
2004
A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
2006 Standout
Cellular mechanisms of tumour suppression by the retinoblastoma gene
2008
TGFβ in Cancer
2008 Standout
PIASy stimulates HIF1α SUMOylation and negatively regulates HIF1α activity in response to hypoxia
2010
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Cancer immunotherapy comes of age
2011 StandoutNature
How important are post-translational modifications in p53 for selectivity in target-gene transcription and tumour suppression?
2007
Silencing of microRNAs in vivo with ‘antagomirs’
2005 StandoutNature
SUMO-1 Modification of the C-terminal KVEKVD of Axin Is Required for JNK Activation but Has No Effect on Wnt Signaling
2002
Cancer Immunotherapy by Dendritic Cells
2008
Phospho-Regulated SUMO Interaction Modules Connect the SUMO System to CK2 Signaling
2009
MDM2-ARF complex regulates p53 sumoylation
2003
Subnuclear segregation of genes and core promoter factors in myogenesis
2011 StandoutNobel
Intraoperative electrocortical stimulation of Brodman area 4: a 10-year analysis of 255 cases
2006
p300 Transcriptional Repression Is Mediated by SUMO Modification
2003
Nuclear and unclear functions of SUMO
2003
Potentiation of Glucocorticoid Receptor Transcriptional Activity by Sumoylation
2002
A Synergy Control Motif within the Attenuator Domain of CCAAT/Enhancer-binding Protein α Inhibits Transcriptional Synergy through Its PIASy-enhanced Modification by SUMO-1 or SUMO-3
2003
Mechanisms maintaining peripheral tolerance
2009
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
The genetics of the p53 pathway, apoptosis and cancer therapy
2008
Structure of the Siz/PIAS SUMO E3 Ligase Siz1 and Determinants Required for SUMO Modification of PCNA
2009
Concepts in sumoylation: a decade on
2007
Multiple activities contribute to Pc2 E3 function
2004
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Disentangling the complexity of the skin dendritic cell network
2010
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Editorial Expression of Concern for multiple articles
2008 StandoutNobel
Phosphorylation-Dependent Interaction of SATB1 and PIAS1 Directs SUMO-Regulated Caspase Cleavage of SATB1
2010
Sumoylation dynamics during keratinocyte differentiation
2006
Modification of GATA-2 Transcriptional Activity in Endothelial Cells by the SUMO E3 Ligase PIASy
2003
Phosphorylation of Serine 303 Is a Prerequisite for the Stress-Inducible SUMO Modification of Heat Shock Factor 1
2003
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase.
1989 StandoutNobel
Rat liver soluble nuclear and cytoplasmic proteins with high affinity to polynucleotides
1975
The role of microRNA genes in papillary thyroid carcinoma
2005 Standout
SUMO-1 Modification of PIASy, an E3 Ligase, Is Necessary for PIASy-Dependent Activation of Tcf-4
2005
Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation
2009
The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation
2005
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
An Acetylation/Deacetylation-SUMOylation Switch through a Phylogenetically Conserved ψKXEP Motif in the Tumor Suppressor HIC1 Regulates Transcriptional Repression Activity
2007
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Regulation of MEF2 by Histone Deacetylase 4- and SIRT1 Deacetylase-Mediated Lysine Modifications
2005
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
2006 StandoutNobel
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Nuclear Protein Kinases from Murine Cells
1975
Hybrid T4 rIIB cistrons created by genetic duplications
1972 StandoutNobel
Repression of Smad transcriptional activity by PIASy, an inhibitor of activated STAT
2003
PIAS proteins promote SUMO-1 conjugation to STAT1
2003
Biochemical characterization of androgen receptor-interacting protein 4
2006
PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription
2007
The Host Defense of Drosophila melanogaster
2007 StandoutNobel
Modification with SUMO
2003
Protein Modification by SUMO
2004 Standout
Selfish DNA: the ultimate parasite
1980 StandoutNature
High resolution two-dimensional electrophoresis of proteins.
1975 Standout
Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxβ
2002
Bacteriophage T4 Gene Expression
1973
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
Circadian control of XPA and excision repair of cisplatin-DNA damage by cryptochrome and HERC2 ubiquitin ligase
2010 StandoutNobel
The Structure and Function of Chromatin
1972
Defining dendritic cells by conditional and constitutive cell ablation
2010
Small ubiquitin-related modifier-1 (SUMO-1) modification of the glucocorticoid receptor
2002
The protein responsible for the repeating structure of cytoplasmic poly(A)-ribonucleoprotein.
1983 StandoutNobel
Multiple domains in Siz SUMO ligases contribute to substrate selectivity
2006
Small ubiquitin-related modifier-1 modification mediates resolution of CREB-dependent responses to hypoxia
2003
Works of Darja Schmidt being referenced
Topography of the cortical motor hand area: prospective study with functional MR imaging and direct motor mapping at surgery.
1995
SUMO: a regulator of gene expression and genome integrity
2004
Viral oncoproteins E1A and E7 and cellular LxCxE proteins repress SUMO modification of the retinoblastoma tumor suppressor
2005
The central sulcal vein: a landmark for identification of the central sulcus using functional magnetic resonance imaging
1996
Constitutive Crosspresentation of Tissue Antigens by Dendritic Cells Controls CD8+ T Cell Tolerance In Vivo
2008
PIAS/SUMO: new partners in transcriptional regulation
2003
Down-Regulation of c-Fos/c-Jun AP-1 Dimer Activity by Sumoylation
2005
Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity
2002
Isolation of RNA‐binding proteins from rat liver nuclear 30 S‐particles
1974
Sumoylation of poly(ADP‐ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function
2009
Involvement of a Phage T4 σ Factor and an Anti-terminator Protein in the Transcription of Early T4 Genes in vivo
1970 Nature