Citation Impact
Citing Papers
Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
2006
Prospective identification of tumorigenic breast cancer cells
2003 Standout
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Evidence for an elevated frequency of in vivo somatic cell mutations in ataxia telangiectasia.
1989
Involvement of tyrosine phosphorylation of p185(c-erbB2/neu) in tumorigenicity induced by X-rays and the neu oncogene in human breast epithelial cells.
1998
The DNA-damage response in human biology and disease
2009 StandoutNature
Involvement of tyrosine phosphorylation of p185c-erbB2/neu in tumorigenicity induced by x-rays and theneu oncogene in human breast epithelial cells
1998
A checkpoint regulates the rate of progression through S phase in S. cerevisiae in Response to DNA damage
1995 StandoutNobel
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Computed Tomography — An Increasing Source of Radiation Exposure
2007 Standout
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
Association of BRCA1 with Rad51 in Mitotic and Meiotic Cells
1997
Cell-cycle checkpoints and cancer
2004 StandoutNature
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
Recent advances in breast cancer biology
1995
Nijmegen breakage syndrome: consequences of defective DNA double strand break repair
1999
The ataxia-telangiectasia gene: a link between checkpoint controls, neurodegeneration and cancer
1995
When Checkpoints Fail
1997 StandoutNobel
ATR: an essential regulator of genome integrity
2008
TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
1995
Immunogenicity of induced pluripotent stem cells
2011 StandoutNature
Pancreatic Adenocarcinoma
2014 Standout
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
1992 Standout
Chromosomes, 11q and cancer: a review
1999
Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology
2006 Standout
Checkpoint Pathways Come of Age
1997 StandoutNobel
The molecular biology of breast cancer
1991
Hypoxia Inhibits G1/S Transition through Regulation of p27 Expression
2001 StandoutNobel
Potential clinical impact of normal-tissue intrinsic radiosensitivity testing
1997
Testing for mutations of the ataxia telangiectasia gene in radiosensitive breast cancer patients
1998
ATM: Genome stability, neuronal development, and cancer cross paths
2001
Foundations in Cancer Research p53 and ATM: Cell Cycle, Cell Death, and Cancer
1997
Cdk1-Dependent Phosphorylation of Cdc13 Coordinates Telomere Elongation during Cell-Cycle Progression
2009 StandoutNobel
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
p21 is a universal inhibitor of cyclin kinases
1993 StandoutNature
p53 is required for radiation-induced apoptosis in mouse thymocytes
1993 StandoutNature
Thymocyte apoptosis induced by p53-dependent and independent pathways
1993 StandoutNature
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members
1999
The Ataxia-telangiectasia mutated gene and breast cancer: gene expression profiles and sequence variants
2005
CDC5 and CKII Control Adaptation to the Yeast DNA Damage Checkpoint
1997 StandoutNobel
Recent advances in breast cancer biology
1999
Creation of human tumour cells with defined genetic elements
1999 StandoutNature
Heterozygosity for mutations in the ataxia telangiectasia gene is not a major cause of radiotherapy complications in breast cancer patients
1998
Flow cytometric analysis of X-ray sensitivity in ataxia telangiectasia
1989
Ataxia-Telangiectasia:Closer to Unraveling the Mystery
1995
Has the breast cancer gene been found?
1994
Synaptic Core Complex of Synaptobrevin, Syntaxin, and SNAP25 Forms High Affinity -SNAP Binding Site
1995 StandoutNobel
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Localization of an ataxia-telangiectasia gene to an approximately 500-kb interval on chromosome 11q23.1: linkage analysis of 176 families by an international consortium.
1995
Characterization of ATM Expression, Localization, and Associated DNA-dependent Protein Kinase Activity
1998
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
1994 StandoutScience
Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling
2010 StandoutNobel
Patient-to-Patient Variability in the Expression of Radiation-Induced Normal Tissue Injury.
1994
Ataxia telangiectasia mutated (Atm) is not required for telomerase-mediated elongation of short telomeres
2006 StandoutNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage
1997
Ataxia-telangiectasia and cellular responses to DNA damage.
1995
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Atm heterozygous mice are more sensitive to radiation-induced cataracts than are their wild-type counterparts
2002
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
1998 StandoutScience
Fragments of ATM Which Have Dominant-Negative or Complementing Activity
1997
Linkage of Early-Onset Familial Breast Cancer to Chromosome 17q21
1990 StandoutScience
The molecular basis of radiosensitivity and chemosensitivity in the treatment of breast cancer
2002
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
ATM-Heterozygous Germline Mutations Contribute to Breast Cancer–Susceptibility
2000
rad -Dependent Response of the chk1 -Encoded Protein Kinase at the DNA Damage Checkpoint
1996 Science
Significance analysis of microarrays applied to the ionizing radiation response
2001 Standout
Regulation of RAD53 by the ATM -Like Kinases MEC1 and TEL1 in Yeast Cell Cycle Checkpoint Pathways
1996 Science
Cancer risks attributable to low doses of ionizing radiation: Assessing what we really know
2003 Standout
Pleiotropic defects in ataxia-telangiectasia protein-deficient mice
1996
Dual roles of ATM in the cellular response to radiation and in cell growth control.
1996 Nobel
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
1996 StandoutScience
Enhanced Phosphorylation of p53 by ATM in Response to DNA Damage
1998 StandoutScience
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Prevalence of germline truncating mutations inATM in women with a second breast cancer after radiation therapy for a contralateral tumor
2000
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Modest increased sensitivity to radiation oncogenesis in ATM heterozygous versus wild-type mammalian cells.
2001
Patient-to-patient variability in the expression of radiation-induced normal tissue injury
1994
Mutations in SDHD , a Mitochondrial Complex II Gene, in Hereditary Paraganglioma
2000 StandoutScience
ATM mutations are associated with inactivation of theARF-TP53 tumor suppressor pathway in diffuse large B-cell lymphoma
2002
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
ATAXIA-TELANGIECTASIA AND THE NIJMEGEN BREAKAGE SYNDROME: Related Disorders But Genes Apart
1997
Works of Daphne Morrell being referenced
Cancer predisposition of ataxia-telangiectasia heterozygotes
1990
Incidence of Cancer in 161 Families Affected by Ataxia–Telangiectasia
1991
Cancers in 44 families with ataxia-telangiectasia
1990
Breast and Other Cancers in Families with Ataxia-Telangiectasia
1987