Citation Impact
Citing Papers
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Toll Pathway-Dependent Blockade of CD4 + CD25 + T Cell-Mediated Suppression by Dendritic Cells
2003 StandoutScience
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Homeostatic maintenance of natural Foxp3 + CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
2005 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Mature mainstream TCR alpha beta+CD4+ thymocytes expressing L-selectin mediate "active tolerance" in the nonobese diabetic mouse.
1998
TLR9 Blockade Inhibits Activation of Diabetogenic CD8+ T Cells and Delays Autoimmune Diabetes
2010
Functional diversity of helper T lymphocytes
1996 StandoutNature
Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice
2003
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases
1995
The Nonobese Diabetic Mouse as a Model of Autoimmune Diabetes: Immune Dysregulation Gets the NOD
1997
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
Alternative Splicing of the N-Terminal Cytosolic and Transmembrane Domains of P2X7 Controls Gating of the Ion Channel by ADP-Ribosylation
2012
The role of IL-12 in the induction of organ-specific autoimmune diseases
1995
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Nucleotide signalling during inflammation
2014 StandoutNature
Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response.
1996 StandoutNobel
Unravelling the pathogenesis of inflammatory bowel disease
2007 StandoutNature
Signals from the gut microbiota to distant organs in physiology and disease
2016
CD4+ T-cell subsets in autoimmunity
1997
Regulatory T Cells
2000 StandoutNobel
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
The inhibitory cytokine IL-35 contributes to regulatory T-cell function
2007 StandoutNature
Pattern Recognition Receptors and Inflammation
2010 Standout
Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non‐obese diabetic mice
1999
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Foxp3+CD25+CD4+ natural regulatory T cells in dominant self‐tolerance and autoimmune disease
2006 StandoutNobel
The third function of the thymus
2000
Cytokines in autoimmunity
1996
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Multiple immuno-regulatory defects in type-1 diabetes
2002
Lymphocyte responses and cytokines
1994 Standout
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate
1996 StandoutNature
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state.
1998
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
2003
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Regulation of autoimmune diabetes by non‐islet‐specific T cells — a role for the glucocorticoid‐induced TNF receptor
2004 StandoutNobel
Interferons and viruses: an evolutionary arms race of molecular interactions
2015 StandoutNobel
Naturally anergic and suppressive CD25+CD4+ T cells as a functionally and phenotypically distinct immunoregulatory T cell subpopulation
2000 StandoutNobel
Genetic Protection from the Inflammatory Disease Type 1 Diabetes in Humans and Animal Models
2001
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
2006
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
2002 StandoutNature
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Experimental Autoimmune Thyroiditis Induced by Thyroglobulin-Pulsed Dendritic Cells
1999
Modulating autoimmune responses to GAD inhibits disease progression and prolongs islet graft survival in diabetes–prone mice
1996
The Complexities of T‐Cell Co‐stimulation: CD28 and Beyond
1996
Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells
1996 StandoutNatureNobel
Genetic Control of Diabetes Progression
1997
Fas Antigen and Sphingomyelin‐Ceramide Turnover‐Mediated Signaling: Role in Life and Death of T Lymphocytes1
1994
Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice.
1996
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
A Subset of CD4 + Thymocytes Selected by MHC Class I Molecules
1994 Science
The Immunological Synapse: A Molecular Machine Controlling T Cell Activation
1999 StandoutScience
T Helper 2 (Th2) T Cells Induce Acute Pancreatitis and Diabetes in Immune-compromised Nonobese Diabetic (NOD) Mice
1997
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Defective CD8+ T Cell Peripheral Tolerance in Nonobese Diabetic Mice
2001
Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4
2000 StandoutNobel
Interleukin-4 Deficiency Does Not Exacerbate Disease in NOD Mice
1998
T Helper Cell Subsets in Insulin-Dependent Diabetes
1995 Science
Interactions Between the Microbiota and the Immune System
2012 StandoutScience
Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation
2000 StandoutNobel
Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells
2003
α/β–T Cell Receptor (TCR)+CD4−CD8− (NKT) Thymocytes Prevent Insulin-dependent Diabetes Mellitus in Nonobese Diabetic (NOD)/Lt Mice by the Influence of Interleukin (IL)-4 and/or IL-10
1998
Identification of Small Heat Shock Protein B8 (HSP22) as a Novel TLR4 Ligand and Potential Involvement in the Pathogenesis of Rheumatoid Arthritis
2006
Simultaneous inhibition of two regulatory T-cell subsets enhanced Interleukin-15 efficacy in a prostate tumor model
2012 StandoutNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice
2011
Multiple immuno-regulatory defects in type-1 diabetes
2002
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Pinpointing when T cell costimulatory receptor CTLA-4 must be engaged to dampen diabetogenic T cells
2000 StandoutNobel
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Regulatory T Cells in the Control of Autoimmunity: the Essential Role of Transforming Growth Factor β and Interleukin 4 in the Prevention of Autoimmune Thyroiditis in Rats by Peripheral CD4+CD45RC− Cells and CD4+CD8− Thymocytes
1999
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Overexpression of Natural Killer T Cells Protects Vα14-Jα281 Transgenic Nonobese Diabetic Mice against Diabetes
1998
THE INTERLEUKIN-12/INTERLEUKIN-12-RECEPTOR SYSTEM: Role in Normal and Pathologic Immune Responses
1998
Impaired Post-Thymic Development of Regulatory CD4+25+ T Cells Contributes to Diabetes Pathogenesis in BB Rats
2005
Thymus and Autoimmunity: Production of CD25+CD4+ Naturally Anergic and Suppressive T Cells as a Key Function of the Thymus in Maintaining Immunologic Self-Tolerance
1999 StandoutNobel
Mature Mainstream TCRαβ+CD4+ Thymocytes Expressing L-Selectin Mediate “Active Tolerance” in the Nonobese Diabetic Mouse
1998
Impaired T cell receptor signaling and development of T cell–mediated autoimmune arthritis
2020 StandoutNobel
Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice
2001
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
Interactions Between Gut Microbiota and Host Metabolism Predisposing to Obesity and Diabetes
2010
CD1 Recognition by Mouse NK1 + T Lymphocytes
1995 StandoutScience
T-cell subsets in autoimmunity
1993
Reciprocal Control of T Helper Cell and Dendritic Cell Differentiation
1999 StandoutScience
Works of Danny Zipris being referenced
TLR9-Signaling Pathways Are Involved in Kilham Rat Virus-Induced Autoimmune Diabetes in the Biobreeding Diabetes-Resistant Rat
2007
The BB/Wor Rat and the Balance Hypothesis of Autoimmunity
1996
The Role of the Intestinal Microbiome in Type 1 Diabetes Pathogenesis
2016
Evidence that Th1 Lymphocytes Predominate in Islet Inflammation and Thyroiditis in the BioBreeding (BB) Rat
1996
Innate immunity and its role in type 1 diabetes
2008
Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms
2009
The BB/Wor Rat and the Balance Hypothesis of Autoimmunity
1996
Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes
2015
Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats.
1996
Interleukin 4 reverses T cell proliferative unresponsiveness and prevents the onset of diabetes in nonobese diabetic mice.
1993
TLR Activation Synergizes with Kilham Rat Virus Infection to Induce Diabetes in BBDR Rats
2005
Expression in BALB/c and C57BL/6 mice of Rt6-1 and Rt6-2 ADP-ribosyltransferases that differ in enzymatic activity: C57BL/6 Rt6-1 is a natural transferase knockout.
1997
Defective thymic T cell activation by concanavalin A and anti-CD3 in autoimmune nonobese diabetic mice. Evidence for thymic T cell anergy that correlates with the onset of insulitis.
1991
Altered Thymic and Peripheral T-Lymphocyte Repertoire Preceding Onset of Diabetes in NOD Mice
1991