Citation Impact
Citing Papers
Akt1 and Akt2 Play Distinct Roles in the Initiation and Metastatic Phases of Mammary Tumor Progression
2009
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
Cathepsin D regulates cathepsin B activation and disease severity predominantly in inflammatory cells during experimental pancreatitis
2017
Activation of FOXO3a by the Green Tea Polyphenol Epigallocatechin-3-Gallate Induces Estrogen Receptor α Expression Reversing Invasive Phenotype of Breast Cancer Cells
2007
Proteolytic Characteristics of Cathepsin D Related to the Recognition and Cleavage of Its Target Proteins
2013
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Role of Estrogen Receptor Gene Demethylation and DNA Methyltransferase·DNA Adduct Formation in 5-Aza-2′deoxycytidine-induced Cytotoxicity In Human Breast Cancer Cells
1997
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Mannose 6-Phosphate Receptor Targeting and its Applications in Human Diseases
2007
Vascular Endothelial Growth Factor-induced Migration of Multiple Myeloma Cells Is Associated with β1 Integrin- and Phosphatidylinositol 3-Kinase-dependent PKCα Activation
2002
Imaging in the era of molecular oncology
2008 StandoutNature
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
1994
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Autophagy: Renovation of Cells and Tissues
2011 Standout
The impact of microRNAs on protein output
2008 StandoutNature
Stromal Cell-Derived Factor 1, a Novel Target of Estrogen Receptor Action, Mediates the Mitogenic Effects of Estradiol in Ovarian and Breast Cancer Cells
2003
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Induction of autophagy and inhibition of tumorigenesis by beclin 1
1999 StandoutNature
Caveolin-1 Potentiates Estrogen Receptor α (ERα) Signaling
1999
Proteomic profiling of mechanistically distinct enzyme classes using a common chemotype
2002
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
Cathepsin D—Many functions of one aspartic protease
2008
Similarities and distinctions in the mode of action of different classes of antioestrogens.
2000
Regulation of protein degradation in normal and transformed human bronchial epithelial cells in culture
1992
A systematic approach to the development of fluorescent contrast agents for optical imaging of mouse cancer models
2007
Virtual and biomolecular screening converge on a selective agonist for GPR30
2006
Proteolytic networks in cancer
2011
Protease sensors for bioimaging
2003
AKT/PKB Signaling: Navigating the Network
2017 Standout
Cathepsin D in the Tumor Microenvironment of Breast and Ovarian Cancers
2020
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Production and Actions of Estrogens
2002 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes
1999 Standout
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Cathepsin-D in primary breast cancer: prognostic evaluation involving 2810 patients
1998
EFFECT OF THE SERINE PROTEASE INHIBITOR N‐TOSYL‐L‐PHENYLALANINE‐CHLOROMETHYL KETONE (TPCK) ON MCF‐7 MAMMARY TUMOUR CELLS GROWTH AND DIFFERENTIATION
2000
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis
2019
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Posttranscriptional regulation of the c-myb proto-oncogene in estrogen receptor-positive breast cancer cells.
1995
Intracellular drug release nanosystems
2012
Selective Antitumor Effect of Novel Protease-Mediated Photodynamic Agent
2006
Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents
2008
In vivo imaging of proteolytic enzyme activity using a novel molecular reporter.
2000
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Ligand-dependent interactions of coactivators steroid receptor coactivator-1 and peroxisome proliferator-activated receptor binding protein with nuclear hormone receptors can be imaged in live cells and are required for transcription
2000 StandoutNobel
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
2001 Standout
Breast cancer classification and prognosis based on gene expression profiles from a population-based study
2003 Standout
LRP-1–CD44, a New Cell Surface Complex Regulating Tumor Cell Adhesion
2012
Repeated observation of breast tumor subtypes in independent gene expression data sets
2003 Standout
A Strategy for the Selective Imaging of Glycans Using Caged Metabolic Precursors
2010 StandoutNobel
New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging
2009 Standout
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Direct Visualization of the Human Estrogen Receptor α Reveals a Role for Ligand in the Nuclear Distribution of the Receptor
1999
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
2001 Standout
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
1996 Standout
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
The Role of DNA Methylation in Mammalian Epigenetics
2001 StandoutScience
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Activatable Photosensitizers for Imaging and Therapy
2010 Standout
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo
2006
Near-infrared optical imaging of proteases in cancer.
2003
Magnetic Nanoparticles: Design and Characterization, Toxicity and Biocompatibility, Pharmaceutical and Biomedical Applications
2012 Standout
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials
2014 Standout
CpG island methylator phenotype in colorectal cancer
1999 Standout
Multiple Myeloma
2011 Standout
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl–mediated drug resistance
2007
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
LRP-1: A Checkpoint for the Extracellular Matrix Proteolysis
2013
Steroid Sulfatase: Molecular Biology, Regulation, and Inhibition
2005
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Danielle Derocq being referenced
Estrogen receptor mediated inhibition of cancer cell invasion and motility: An overview
1998
Anti‐proliferative and anti‐estrogenic effects of ICI 164,384 and ICI 182,780 in 4‐OH‐tamoxifen‐resistant human breast‐cancer cells
1994
Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis
2005
Processing of Human Cathepsin D Is Independent of Its Catalytic Function and Auto-Activation: Involvement of Cathepsins L and B
2006
Cloning and Sequencing of the 52K Cathepsin D Complementary Deoxyribonucleic Acid of MCF7 Breast Cancer Cells and Mapping on Chromosome 11
1988
Cathepsin-D, a Key Protease in Breast Cancer, Is Up-Regulated in Obese Mouse and Human Adipose Tissue, and Controls Adipogenesis
2011
Cathepsin D is partly endocytosed by the LRP1 receptor and inhibits LRP1-regulated intramembrane proteolysis
2011
Breast cancer cell invasiveness: Correlation with protein kinase C activity and differential regulation by phorbol ester in estrogen receptor-positive and -negative cells
1998
Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells
2002
Overexpression of transfected cathepsin D in transformed cells increases their malignant phenotype and metastatic potency.
1990
Transfected cathepsin D stimulates high density cancer cell growth by inactivating secreted growth inhibitors.
1995
Proteolysis of cystatin C by cathepsin D in the breast cancer microenvironment
2012
Activation of estrogen receptor transfected into a receptor-negative breast cancer cell line decreases the metastatic and invasive potential of the cells.
1992
Pro-cathepsin D interacts with the extracellular domain of the β chain of LRP1 and promotes LRP1-dependent fibroblast outgrowth
2010
Biological and Clinical Significance of Cathepsin D in Breast Cancer Metastasis
1996
Effects of Plasma Estrogen Sulfates in Mammary Cancer Cells*
1980