Standout Papers
Citation Impact
Citing Papers
Helicobacter pylori evolution during progression from chronic atrophic gastritis to gastric cancer and its impact on gastric stem cells
2008
Global Transposon Mutagenesis and Essential Gene Analysis of Helicobacter pylori
2004
The Helicobacter pylori Vacuolating Toxin Inhibits T Cell Activation by Two Independent Mechanisms
2003
Molecular Analysis of Commensal Host-Microbial Relationships in the Intestine
2001 StandoutScience
SHP-2 Tyrosine Phosphatase as an Intracellular Target of Helicobacter pylori CagA Protein
2002 Science
Prevention of Helicobacter pylori infection by lactobacilli in a gnotobiotic murine model.
1997
Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains
1997
Eradication of chronic Helicobacter pylori infection by therapeutic vaccination
1998
Heterogeneity in the Helicobacter pylori vacA and cagA genes: association with gastroduodenal disease in South Africa?
1999
Profile of Helicobacter pylori cytotoxin derived from two areas of Japan with different prevalence of atrophic gastritis.
1996
Major virulence factors, VacA and CagA, are commonly positive in Helicobacter pylori isolates in Japan
1998
Spontaneous Large-Scale Lymphoid Neogenesis and Balanced Autoimmunity versus Tolerance in the Stomach of H+/K+-ATPase-Reactive TCR Transgenic Mouse
2006 StandoutNobel
Low pH Activates the Vacuolating Toxin of Helicobacter pylori, Which Becomes Acid and Pepsin Resistant
1995
Effect of Helicobacter pylori Vacuolating Toxin on Maturation and Extracellular Release of Procathepsin D and on Epidermal Growth Factor Degradation
1997
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2024 Standout
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries
2021 Standout
Gene activities that mediate increased life span of C. elegans insulin-like signaling mutants
2007 StandoutNobel
Helicobacter pylori, T cells and cytokines: the âdangerous liaisonsâ
2004
Heterogeneity ofHelicobacter pylori caggenotypes in experimentally infected mice
2001
Malignant Helicobacter pylori-Associated Diseases: Gastric Cancer and MALT Lymphoma
2019
Corrected Identity of Isolates of Helicobacter Pylori Reference Strain NCTC11637
1997
Inflammation and cancer
2002 StandoutNature
Helicobacter pylori Vacuolating Cytotoxin, VacA, Is Responsible for Gastric Ulceration
2004
Immunization of BALB/c mice with Helicobacter urease B induces a T helper 2 response absent in Helicobacter infection
1998
Identification of nonessential Helicobacter pylori genes using random mutagenesis and loop amplification
2001
Analysis of host responses of guinea pigs during Helicobacter pylori infection
2001
Flt3 Signaling-Dependent Dendritic Cells Protect against Atherosclerosis
2011 StandoutNobel
Severe Gastritis in Guinea-Pigs Infected with Helicobacter Pylori
1998
Variability of gene order in different Helicobacter pylori strains contributes to genome diversity
1996
The Helicobacter pylori neutrophil‐activating protein is an iron‐binding protein with dodecameric structure
1999
Th1/Th2 Cells
1999
Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori?
1997
Lack of gastritis and of an adaptive immune response in interferon regulatory factor-1-deficient mice infected withHelicobacter pylori
2001
The Effect of Infections on Susceptibility to Autoimmune and Allergic Diseases
2002 Standout
Helicobacter pylorivacuolating cytotoxin enters cells, localizes to the mitochondria, and induces mitochondrial membrane permeability changes correlated to toxin channel activity
2004
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
Induction of ulceration and severe gastritis in Mongolian gerbil by Helicobacter pylori infection
1997
Unravelling the pathogenic role of Helicobacter pylori in peptic ulcer: Potential new therapies and vaccines
1994
Gastric autoimmunity: the role of Helicobacter pylori and molecular mimicry
2004
A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: Identification of duplicated repeats and potential active site residues
1996
VacA from Helicobacter pylori: a hexameric chloride channel
1999
Helicobacter pylori toxin VacA induces vacuole formation by acting in the cell cytosol
1997
Genetic organization and heterogeneity of the iceA locus of Helicobacter pylori
2000
Emergence of recombinant strains ofHelicobacter pyloriduring human infection
1999
Activation of Helicobacter pylori VacA Toxin by Alkaline or Acid Conditions Increases Its Binding to a 250-kDa Receptor Protein-tyrosine Phosphatase β
1999
Prevalence of Vacuolating Cytotoxin Production and Distribution of Distinct vacA Alleles in Helicobacter pylori from China
1998
Cellular Vacuolation and Mitochondrial Cytochrome c Release Are Independent Outcomes of Helicobacter pylori Vacuolating Cytotoxin Activity That Are Each Dependent on Membrane Channel Formation
2003
Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin.
1998
Molecular and cellular mechanisms of action of the vacuolating cytotoxin (VacA) and neutrophil-activating protein (HP-NAP) virulence factors of Helicobacter pylori
2003
Quasispecies Development ofHelicobacter pyloriObserved in Paired Isolates Obtained Years Apart from the Same Host
2000
Protection against Helicobacter pylori infection in mice by intragastric vaccination with H. pylori antigens is achieved using a non-toxic mutant of E. coli heat-labile enterotoxin (LT) as adjuvant
1998
Helicobacter pylori Vacuolating Cytotoxin Induces Activation of the Proapoptotic Proteins Bax and Bak, Leading to Cytochrome c Release and Cell Death, Independent of Vacuolation
2006
Clinical relevance of the cagA, vacA, and iceA status of Helicobacter pylori
1998
Systemic sclerosis
2017 Standout
The N-terminal 34 kDa fragment of Helicobacter pylori vacuolating cytotoxin targets mitochondria and induces cytochrome c release
2000
The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori
2004
IMMUNOLOGY OF HELICOBACTER PYLORI AND PROSPECTS FOR VACCINE
2000
Presence of the cagA Gene in the Majority of Helicobacter pylori Strains Is Independent of Whether the Individual Has Duodenal Ulcer or Asymptomatic Gastritis
1996
Molecular mimicry of ferret gastric epithelial blood group antigen A by Helicobacter mustelae
1998
Human immune response towards recombinant Helicobacter pylori urease and cellular fractions
2005
Helicobacter pylori in Health and Disease
2009
Rab GTPases as coordinators of vesicle traffic
2009 Standout
Genetic organization of a small cryptic plasmid of Helicobacter pylori
1995
Protective Anti‐HelicobacterImmunity Is Induced with Aluminum Hydroxide or Complete Freund's Adjuvant by Systemic Immunization
2001
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Multiple Oligomeric States of the Helicobacter pylori Vacuolating Toxin Demonstrated by Cryo-electron Microscopy
2002 StandoutNobel
Role of the Microbiota in Immunity and Inflammation
2014 Standout
Helicobacter pylori Infection and the Development of Gastric Cancer
2001 Standout
Analysis of the type IV secretion system-dependent cell motility of Helicobacter pylori-infected epithelial cells
2004
Mosaicism in Vacuolating Cytotoxin Alleles of Helicobacter pylori
1995
The Story So Far:Helicobacter Pyloriand Gastric Autoimmunity
2005
The Acid Activation ofHelicobacter pyloriToxin VacA: Structural and Membrane Binding Studies
1998
Vaccination of Gnotobiotic Piglets againstHelicobacter pylori
1998
Oral immunization with urease and Escherichia coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori–infected adults
1999
GastricHelicobacterSpecies Infection in Murine and Gerbil Models: Comparative Analysis of Effects ofH. pyloriandH. felison Gastric Epithelial Cell Proliferation
2002
Severe Inflammation and Reduced Bacteria Load in MurineHelicobacterInfection Caused by Lack of Phagocyte Oxidase Activity
2003
The Interrelationship between Cytotoxin-Associated Gene A, Vacuolating Cytotoxin, and Helicobacter pylori-Related Diseases
1996
Bacterial protein toxins and cell vesicle trafficking
1996
Selective Interaction of Complexin with the Neuronal SNARE Complex
2000 StandoutNobel
Reduced colonization of gastric mucosa by Helicobacter pylori in mice deficient in interleukin‐101
2001
Oncogenic mechanisms of the Helicobacter pylori CagA protein
2004
Host Response and Vaccine Development to Helicobacter pylori Infection
1999
Treatment of Helicobacter pylori infection in rhesus monkeys using a novel antiadhesion compound
1999
Density of Helicobacter pylori Infection In Vivo as Assessed by Quantitative Culture and Histology
1996
Helicobacter pylori Vacuolating Toxin Forms Anion-Selective Channels in Planar Lipid Bilayers: Possible Implications for the Mechanism of Cellular Vacuolation
1999
The Impact of the Gut Microbiota on Human Health: An Integrative View
2012 Standout
Genetic analysis of the Helicobacter pylori vacuoiating cytotoxin: structural similarities with the IgA protease type of exported protein
1994
Induction of gastric ulcer and intestinal metaplasia in Mongolian gerbils infected withHelicobacter pylori
1996
Helicobacter pylori VacA, a paradigm for toxin multifunctionality
2005
Modelling human development and disease in pluripotent stem-cell-derived gastric organoids
2014 Nature
Helicobacter pylori Infection and Gastric Lymphoma
1994 Standout
Genetic and functional characterization of the alpAB gene locus essential for the adhesion of Helicobacter pylori to human gastric tissue
1999
The primary transcriptome of the major human pathogen Helicobacter pylori
2010 StandoutNature
Specific Immunoglobulin A Antibodies in Maternal Milk and Delayed Helicobacter pylori Colonization in Gambian Infants
2004
Analyses of the cag pathogenicity island of Helicobacter pylori
1998
Antral Atrophy,Helicobacter pyloriColonization, and Gastric pH
1996
c‐Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs
2002
Expression of mRNA for Interferon-Gamma, Interleukin-10, and Interleukin-12 (p40) in Normal Gastric Mucosa and in Mucosa Infected withHelicobacter pylori
1997
Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori
2004
Structure and interaction of VacA of Helicobacter pylori with a lipid membrane
2000
Helicobacter pylori CagA Containing ITAM‐Like Sequences Localized to Lipid Rafts Negatively Regulates VacA‐Induced Signaling In Vivo
2003
A revised annotation and comparative analysis of Helicobacter pylori genomes
2003
Coadaptation of Helicobacter pylori and humans: ancient history, modern implications
2009
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Activation of Activator Protein 1 and Stress Response Kinases in Epithelial Cells Colonized by Helicobacter pylori Encoding the cag Pathogenicity Island
1999
Gut flora in health and disease
2003 Standout
Three-Dimensional Reconstruction of Metal Replicas of theHelicobacter pyloriVacuolating Cytotoxin
1998
The vacuolating cytotoxin of Helicobacter pylori
1996
Idiopathic Pulmonary Fibrosis
2001 Standout
Delayed infection, family size and malignant lymphomas
2000
Gastric cancer
2020 Standout
High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy
2005 StandoutNobel
Orogastric vaccination of guinea pigs withHelicobacter pylorisonicate and a high dose of cholera toxin lowers the burden of infection
2003
Helicobacter pyloriInfection
2002 Standout
Helicobacter pylori infection enhances glandular stomach carcinogenesis in Mongolian gerbils treated with chemical carcinogens
1999
Prospects for the Development of a Vaccine Against Helicobacter pylori
1996
Attenuation of Helicobacter pylori CagA·SHP-2 Signaling by Interaction between CagA and C-terminal Src Kinase
2003
A predominant Th1 type of immune response is induced early during acute Helicobacter pylori infection in rhesus macaques
2000
Ordered cosmid library and high‐resolution physical—genetic map of Helicobacter pylori strain NCTC11638
1994
Recombination and clonal groupings within Helicobacter pylori from different geographical regions
1999
Functional analysis of iceA1, a CATG-recognizing restriction endonuclease gene in Helicobacter pylori
2002
Environmental risk factors of systemic sclerosis
2015
Helicobacter pylori Eradication to Prevent Gastric Cancer in a High-Risk Region of China
2004 Standout
Analysis of iceA1 transcription in Helicobacter pylori
2000
Association between TNF- promoter polymorphism and Helicobacter pylori cagA subtype infection
2001
Formation of anion-selective channels in the cell plasma membrane by the toxin VacA of Helicobacter pylori is required for its biological activity
1999
Helicobacter pylori and Schistosoma japonicum co-infection in a Chinese population: helminth infection alters humoral responses to H. pylori and serum pepsinogen I/II ratio
2005
Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori
1993 Standout
Inflammatory Cytokine mRNA Expression during Early and PersistentHelicobacter pyloriInfection in Nonhuman Primates
2000
Association of Helicobacter pylori genotype with gastroesophageal reflux disease and other upper gastrointestinal diseases
2000
3D imaging of the 58 kda cell binding subunit of the Helicobacter pylori cytotoxin
1999
Src Is the Kinase of the Helicobacter pylori CagA Protein in Vitro and in Vivo
2002
Expression of Interleukin‐18, a Th1 Cytokine, in Human Gastric Mucosa Is Increased inHelicobacter pyloriInfection
2001
Helicobacter pylori: molecular evolution of a bacterial quasi-species
1998
The response of cells from low-grade B-cell gastric lymphomas of mucosa-associated lymphoid tissue to Helicobacter pylori
1993
Potential Role of CagA in the Inhibition of T Cell Reactivity in Helicobacter pylori Infections
2000
Essential Role of a GXXXG Motif for Membrane Channel Formation by Helicobacter pylori Vacuolating Toxin
2003
Duodenal Helicobacter pylori infection differs in cagA genotype between asymptomatic subjects and patients with duodenal ulcers
1999
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Regulation of transcription in Helicobacter pylori: simple systems or complex circuits?
2001
Functional Properties of the p33 and p55 Domains of the Helicobacter pylori Vacuolating Cytotoxin
2005
Correlation between Variation of the 3′ Region of thecagAGene inHelicobacter pyloriand Disease Outcome in Japan
2002
The Sialic Acid Binding SabA Adhesin of Helicobacter pylori Is Essential for Nonopsonic Activation of Human Neutrophils
2005
Vacuoles Induced by Helicobacter pylori Toxin Contain Both Late Endosomal and Lysosomal Markers
1997
A Dominant Negative Mutant of Helicobacter pyloriVacuolating Toxin (VacA) Inhibits VacA-induced Cell Vacuolation
1999
The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin
1997
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Helicobacter pylori and gastrointestinal tract adenocarcinomas
2002
The Helicobacter pylori CagA protein induces cortactin dephosphorylation and actin rearrangement by c-Src inactivation
2003
Vacuolating Toxin Production in Clinical Isolates of Helicobacter pylori with Different vacA Genotypes
1998
Modeling Development and Disease with Organoids
2016 Standout
Mice deficient in protein tyrosine phosphatase receptor type Z are resistant to gastric ulcer induction by VacA of Helicobacter pylori
2003
Protection against Helicobacter pylori infection in the Mongolian gerbil after prophylactic vaccination
2005
The Functional Status of the Helicobacter pylori sabB Adhesin Gene as a Putative Marker for Disease Outcome
2004
The gut microbiota shapes intestinal immune responses during health and disease
2009 Standout
The significance of cagA and vacA subtypes of Helicobacter pylori in the pathogenesis of inflammation and peptic ulceration.
1998
Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype.
1995
Yersinia pestis , the cause of plague, is a recently emerged clone of Yersinia pseudotuberculosis
1999 Standout
The crystal structure of urease from Klebsiella aerogenes
1995 StandoutScience
Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity
1999
Translocation of Helicobacter pylori CagA into Gastric Epithelial Cells by Type IV Secretion
2000 StandoutScience
Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin.
1996
Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection
1997
The vacuolating toxin from Helicobacter pylori forms hexameric pores in lipid bilayers at low pH
1999
Gut Microbiota in Health and Disease
2010 Standout
Helicobacter pyloriModulates the T Helper Cell 1/T Helper Cell 2 Balance through Phase-variable Interaction between Lipopolysaccharide and DC-SIGN
2004
Rectal and Intranasal Immunizations with Recombinant Urease Induce Distinct Local and Serum Immune Responses in Mice and Protect against Helicobacter pylori Infection
1998
Animal models of Helicobacter pylori infection and disease
2003
Virulence Factors of Helicobacter pylori Responsible for Gastric Diseases in Mongolian Gerbil
2000
In vivo distribution and activity of aphidicolin on dividing and quiescent cells
1985 StandoutNobel
Interleukin-8 response of gastric epithelial cell lines to Helicobacter pylori stimulation in vitro
1995
Depletion of Neutrophils in IL-10−/− Mice Delays Clearance of Gastric Helicobacter Infection and Decreases the Th1 Immune Response to Helicobacter
2003
Tyrosine phosphorylation of theHelicobacter pyloriCagA antigen aftercag-driven host cell translocation
2000
Key importance of the Helicobacter pylori adherence factor blood group antigen binding adhesin during chronic gastric inflammation.
2001
Infection withHelicobacter pyloriExpressing thecagAGene Is Not Associated with an Increased Risk of Developing Peptic Ulcer Diseases in Korean Patients
1998
Expression of the Programmed Death Ligand 1, B7-H1, on Gastric Epithelial Cells afterHelicobacter pyloriExposure Promotes Development of CD4+CD25+FoxP3+Regulatory T Cells
2007
Immunization of Mice with Urease Vaccine Affords Protection against Helicobacter pylori Infection in the Absence of Antibodies and Is Mediated by MHC Class II–restricted Responses
1998
Serologic detection of infection with cagA+ Helicobacter pylori strains
1995
Mechanism of inhibition of herpes simplex virus and vaccinia virus DNA polymerases by aphidicolin, a highly specific inhibitor of DNA replication in eucaryotes
1980
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Gastric Ulcer, Atrophic Gastritis, and Intestinal Metaplasia Caused byHelicobacter pyloriInfection in Mongolian Gerbils
1998
Adaptive mutation and cocolonization during Helicobacter pylori infection of gnotobiotic piglets
1995
Acid activation of Helicobacter pylori vacuolating cytotoxin (VacA) results in toxin internalization by eukaryotic cells
2000
cag , a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors
1996 Standout
Immunization against NaturalHelicobacter pyloriInfection in Nonhuman Primates
1998
A 12-Amino-Acid Segment, Present in Type s2 but Not Type s1 Helicobacter pylori VacA Proteins, Abolishes Cytotoxin Activity and Alters Membrane Channel Formation
2001
Mutation of the cytotoxin-associated cagA gene does not affect the vacuolating cytotoxin activity of Helicobacter pylori
1994
Helicobacter pylori toxin VacA is transferred to host cells via a novel contact-dependent mechanism
2004
Helicobacter pylori - a conundrum of genetic diversity
1998
Occurrence of gastric ulcers in gnotobiotic piglets colonized by Helicobacter pylori
1995
All subtypes of the cytotoxin VacA adsorb to the surface of Helicobacter pylori post-secretion
2005
Polymorphisms of Helicobacter pylori HP0638 Reflect Geographic Origin and Correlate with cagA Status
2002
Host Cell Responses to Genotypically SimilarHelicobacter pyloriIsolates from United States and Japan
2002
Proteins Encoded by thecagPathogenicity Island ofHelicobacter pyloriAre Required for NF-κB Activation
1998
The Helicobacter pylori Blood Group Antigen-Binding Adhesin Facilitates Bacterial Colonization and Augments a Nonspecific Immune Response
2002
Local Cytokine Response inHelicobacter pylori-Infected Subjects
1998
Acid-induced Dissociation of VacA, the Helicobacter pylori Vacuolating Cytotoxin, Reveals Its Pattern of Assembly
1997
The Helicobacter pylori vacuoloating cytotoxin: from cellular vacuolation to immunosuppressive activities
2004
Amino-Terminal Hydrophobic Region of Helicobacter pylori Vacuolating Cytotoxin (VacA) Mediates Transmembrane Protein Dimerization
2001
Motility of Helicobacter pylori Is Coordinately Regulated by the Transcriptional Activator FlgR, an NtrC Homolog
1999
Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin
1995
Pathogenesis ofHelicobacter pyloriInfection
2006 Standout
Detection ofHelicobacter species in the liver of patients with and without primary liver carcinoma
2000
Vacuolating Cytotoxin of Helicobacter pylori Plays a Role during Colonization in a Mouse Model of Infection
2001
Evaluation of the Association of NineHelicobacter pyloriVirulence Factors with Strains Involved in Low-Grade Gastric Mucosa-Associated Lymphoid Tissue Lymphoma
2004
Modulation of Innate Cytokine Responses by Products ofHelicobacter pylori
2000
Helicobacter pyloriInfection in Immunized Mice Lacking Major Histocompatibility Complex Class I and Class II Functions
1999
Expression of B7-H1 on Gastric Epithelial Cells: Its Potential Role in Regulating T Cells during Helicobacter pylori Infection
2006
Cure ofHelicobacter pyloriInfection and Resolution of Gastritis by Adoptive Transfer of Splenocytes in Mice
2001
Detection of Helicobacter species in the liver of patients with and without primary liver carcinoma.
2000
Surface localization of Helicobacter pylori urease and a heat shock protein homolog requires bacterial autolysis
1996
Crystal structure of CagV, the Helicobacter pylori homologue of the T4SS protein VirB8
2019
Emergence of DiverseHelicobacterSpecies in the Pathogenesis of Gastric and Enterohepatic Diseases
2001
Mucosal Adjuvanticity and Immunogenicity of LTR72, a Novel Mutant of Escherichia coli Heat-labile Enterotoxin with Partial Knockout of ADP-ribosyltransferase Activity
1998
Expanding Allelic Diversity of Helicobacter pylori vacA
1998
CagA/cytotoxic strains of Helicobacter pylori and interleukin-8 in gastric epithelial cell lines.
1994
Molecular biology of microbial ureases
1995 Standout
Vacuolating Cytotoxin of Helicobacter pylori Induces Apoptosis in the Human Gastric Epithelial Cell Line AGS
2001
Th1/Th2 cells
2007
Identification and characterization of an operon of Helicobacter pylori that is involved in motility and stress adaptation
1997
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomach.
1995 Standout
Vaccination against Helicobacter pylori - an old companion of man
2001
Transient and persistent experimental infection of nonhuman primates with Helicobacter pylori: implications for human disease
1996
Role of the Helicobacter pylori outer-membrane proteins AlpA and AlpB in colonization of the guinea pig stomach
2004
Frontiers, Opportunities, and Challenges in Biochemical and Chemical Catalysis of CO2 Fixation
2013 Standout
Helicobacter pyloriDoes Not Require Lewis X or Lewis Y Expression To Colonize C3H/HeJ mice
2002
Helicobacter pylori VacA Toxin Promotes Bacterial Intracellular Survival in Gastric Epithelial Cells
2006
Creating and Maintaining the Gastrointestinal Ecosystem: What We Know and Need To Know from Gnotobiology
1998
Helicobacter pylori Adhesin Binding Fucosylated Histo-Blood Group Antigens Revealed by Retagging
1998 StandoutScience
Helicobacter pylori-Induced Mucosal Inflammation Is Th1 Mediated and Exacerbated in IL-4, But Not IFN-γ, Gene-Deficient Mice
2000
Helicobacter pylori Virulence and Genetic Geography
1999 StandoutScience
Negative Selection of T Cells byHelicobacter pylorias a Model for Bacterial Strain Selection by Immune Evasion
2001
Metabolism and Genetics of Helicobacter pylori : the Genome Era
1999
Clustering and Redistribution of Late Endocytic Compartments in Response toHelicobacter pyloriVacuolating Toxin
2004
Aphidicolin: a specific inhibitor of nuclear DNA replication in eukaryotes
1982
cagA -Positive Helicobacter pylori Populations in China and The Netherlands Are Distinct
1998
Helicobacter pylori Caga Protein Can Be Tyrosine Phosphorylated in Gastric Epithelial Cells
2000
Vacuolating Toxin Gene Polymorphism amongHelicobacter pyloriClinical Isolates and Its Association with m1, m2, or ChimericvacAMiddle Types
1998
Human Dendritic Cells Respond to Helicobacter pylori, Promoting NK Cell and Th1-Effector Responses In Vitro
2004
Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease
1995
Evolution of the Helicobacter pylori Vacuolating Cytotoxin in a Human Stomach
2004
TheHelicobacter pyloriplasticity region locusjhp0947âjhp0949is associated with duodenal ulcer disease and interleukin-12 production in monocyte cells
2004
Experimental Infection of Mongolian Gerbils with Wild-Type and Mutant Helicobacter pylori Strains
1998
Seroprevalence of cytotoxin‐associated gene A positive Helicobacter pylori strains in Changle, an area with very high prevalence of gastric cancer in South China
1999
The Disease Spectrum ofHelicobacter Pylori: The Immunopathogenesis of Gastroduodenal Ulcer and Gastric Cancer
2000
Human 60-kDa Heat Shock Protein Is a Target Autoantigen of T Cells Derived from Atherosclerotic Plaques
2005
An autoradiographic demonstration of nuclear DNA replication by DNA polymerase α and of mitochondrial DNA synthesis by DNA polymerase γ
1981
pH-Regulated Gene Expression of the Gastric PathogenHelicobacter pylori
2003
Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites
2002
The New Path to Preventing Ulcers
1995 Science
Analysis and typing of the vacA gene from cagA-positive strains of Helicobacter pylori isolated in Japan
1997
Structure of cag pathogenicity island in Japanese Helicobacter pyloriisolates
1999
Induction of gastric epithelial cell apoptosis by Helicobacter pylori vacuolating cytotoxin.
2003
Spiral Bacteria in the Human Stomach: The Gastric Helicobacters
1995
Inhibition of primary human T cell proliferation byHelicobacter pylorivacuolating toxin (VacA) is independent of VacA effects on IL-2 secretion
2004
Molecular Mimicry between Helicobacter pylori Antigens and H+,K+–Adenosine Triphosphatase in Human Gastric Autoimmunity
2003
Increased frequency of activated T-cells in theHelicobacter pylori-infected antrum and duodenum
2003
Induction of host signal transduction pathways by Helicobacter pylori
1997
Divergence of genetic sequences for the vacuolating cytotoxin among Helicobacter pylori strains.
1994
PD-1 and Its Ligands in Tolerance and Immunity
2008 Standout
Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori.
1995
Distinct Variants of Helicobacter pylori cagA Are Associated with vacA Subtypes
1999
An enzymatic method for microdetermination of aphidicolin: A promising anticancer drug
1981
SMART, a simple modular architecture research tool: Identification of signaling domains
1998 Standout
Chemical Glycoproteomics
2016 StandoutNobel
Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin
1999
Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis
1998 StandoutScience
The Role of T Cell Subsets and Cytokines in the Pathogenesis of Helicobacter pylori Gastritis in Mice
2001
Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high‐affinity ferrous iron transporter
2000
Works of Daniela Burroni being referenced
cag A positive and negative Helicobacter pylori strains are simultaneously present in the stomach of most patients with non-ulcer dyspepsia: relevance to histological damage
1998
Generation of a monoclonal antibody to a defined portion of the Helicobacter pylori vacuolating cytotoxin by DNA immunization
1996
Different cytokine profile and antigen‐specificity repertoire in Helicobacter pylori‐specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer
1997
Evolution of functional polymorphism in the gene coding for theHelicobacter pyloricytotoxin
2002
The Hsp60 protein of Helicobacter pylori: structure and immune response in patients with gastroduodenal diseases
1993
Characterisation of a monoclonal antibody and its use to purify the cytotoxin ofHelicobacter pylori
1998
Lipid Interaction of the 37‐kDa and 58‐kDa Fragments of the Helicobacter Pylori Cytotoxin
1995
Functional roles of the plant α‐like and γ‐like DNA polymerases
1981
Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease.
1994
Cell Specificity of Helicobacter pylori Cytotoxin Is Determined by a Short Region in the Polymorphic Midregion
2000
A Conventional Beagle Dog Model for Acute and Chronic Infection withHelicobacter pylori
1999
Molecular characterization of the 128-kDa immunodominant antigen of Helicobacter pylori associated with cytotoxicity and duodenal ulcer.
1993 Standout
T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease.
1997
Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies
1995
Binding of theHelicobacter pyloriVacuolating Cytotoxin to Target Cells
1998
Identification of the Helicobacter pylori VacA Toxin Domain Active in the Cell Cytosol
1998
Deletion of the Major Proteolytic Site of the Helicobacter pylori Cytotoxin Does Not Influence Toxin Activity but Favors Assembly of the Toxin into Hexameric Structures
1998
Development of a Mouse Model of Helicobacter pylori Infection that Mimics Human Disease
1995 Science
Specific and reversible inhibition by aphidicolin of the α‐like DNA polymerase of plant cells
1980
The m2 form of the Helicobacter pylori cytotoxin has cell type-specific vacuolating activity
1998