Standout Papers
- Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency. (2000)
Citation Impact
Citing Papers
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β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
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2000
Rac1 and Rac2 GTPases in haematopoiesis
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Oncogenic kinase signalling
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Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication
1990
Gene Transfer into Hematopoietic Stem Cells
1992
Osteoblastic cells regulate the haematopoietic stem cell niche
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The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
Functional neurogenesis in the adult hippocampus
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Proliferation, cell cycle and apoptosis in cancer
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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
1995 StandoutNature
Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells (MSCs) and stromal cells
1998
Factors affecting long-term stability of Moloney murine leukemia virus-based vectors
1989
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
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Coordinated cytokine expression by stromal and hematopoietic cells during human osteoclast formation
2000
The bone marrow niche for haematopoietic stem cells
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Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture
1992
Interleukin 6 and its Receptor: Ten Years Later
1998
4 Primate Embryonic Stem Cells
1997
Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: Implications for gene therapy
1996
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
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A role for Wnt signalling in self-renewal of haematopoietic stem cells
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Rac2 Specificity in Macrophage Integrin Signaling
2003
Nopp 140 shuttles on tracks between nucleolus and cytoplasm
1992 StandoutNobel
Cytokine signal transduction
1994
Abnormal splicing of the leptin receptor in diabetic mice
1996 StandoutNature
Derivation of pluripotent epiblast stem cells from mammalian embryos
2007 StandoutNature
Regulation of neutrophil function by Rac GTPases
2003
Identification of Three Distinct Receptor Binding Sites of Murine Interleukin-11
1999
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
2000 StandoutNature
Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells
1996
Cancer-related inflammation
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Wnt signalling in stem cells and cancer
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1999
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2006
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2008
Multilineage Potential of Adult Human Mesenchymal Stem Cells
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1994
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2008 StandoutNobel
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
Cloning of a murine IL-11 receptor alpha-chain; requirement for gp130 for high affinity binding and signal transduction.
1994
Protection of bone marrow transplant recipients from lethal doses of methotrexate by the generation of methotrexate-resistant bone marrow.
1987
Inhibition of hematopoietic development from embryonic stem cells by antisense vav RNA.
1993
Rac2 Regulates Neutrophil Chemotaxis, Superoxide Production, and Myeloid Colony Formation through Multiple Distinct Effector Pathways
2005
Chromosomal position or virus mutation permits retrovirus expression in embryonal carcinoma cells
1986
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Neurexin III alpha: extensive alternative splicing generates membrane-bound and soluble forms.
1993 StandoutNobel
Chemoattractant-Stimulated Rac Activation in Wild-Type and Rac2-Deficient Murine Neutrophils: Preferential Activation of Rac2 and Rac2 Gene Dosage Effect on Neutrophil Functions
2002
RhoH, a hematopoietic-specific Rho GTPase, regulates proliferation, survival, migration, and engraftment of hematopoietic progenitor cells
2004
Transplantable myeloproliferative disease induced in mice by an interleukin 6 retrovirus.
1992
Induction of Chronic Myelogenous Leukemia in Mice by the P210 bcr/abl Gene of the Philadelphia Chromosome
1990 StandoutScienceNobel
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
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Direct Gene Transfer into Mouse Muscle in Vivo
1990 StandoutScience
Proliferation of multipotent hematopoietic cells controlled by a truncated erythropoietin receptor transgene.
1996 StandoutNobel
Gene Therapy of Human Severe Combined Immunodeficiency (SCID)-X1 Disease
2000 StandoutScience
Cross-talk between RhoH and Rac1 in regulation of actin cytoskeleton and chemotaxis of hematopoietic progenitor cells
2007
RhoG Regulates the Neutrophil NADPH Oxidase
2006
Rac and Cdc42 GTPases control hematopoietic stem cell shape, adhesion, migration, and mobilization
2001
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
An essential role for Rac1 in endothelial cell function and vascular development
2008
Hematopoietic Commitment During Embryonic Stem Cell Differentiation in Culture
1993
Somatic gene therapy for human disease: Background and prospects. Part I
1987
Thrombocytosis in patients with tumors producing colony-stimulating factor
1992 StandoutNobel
Rac2-Deficient Hematopoietic Stem Cells Show Defective Interaction with the Hematopoietic Microenvironment and Long-Term Engraftment Failure
2005
Human osteoblasts support human hematopoietic progenitor cells in vitro bone marrow cultures
1996
Stem Cell Factor and Hematopoiesis
1997
Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
1995 StandoutNobel
An analysis of vertebrate mRNA sequences: intimations of translational control.
1991 Standout
Specification of Cerebral Cortical Areas
1988 StandoutScience
Progress Toward Human Gene Therapy
1989 Science
Hematopoietic cytokines
2008
Improved gene expression upon transfer of the adenosine deaminase minigene outside the transcriptional unit of a retroviral vector.
1989
Rac2 Is an Essential Regulator of Neutrophil Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Response to Specific Signaling Pathways
2001
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
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Human osteoblasts support hematopoiesis through the production of granulocyte colony-stimulating factor.
1994
Neural Cell Adhesion Molecule Contributes to Hemopoiesis‐Supporting Capacity of Stromal Cell Lines
2005
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 StandoutScience
Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.
1992 StandoutNobel
Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer.
1987
Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection.
1990
Gene Transfer by Retrovirus Vectors Occurs Only in Cells That Are Actively Replicating at the Time of Infection
1990
Rac2-Deficient Murine Macrophages Have Selective Defects in Superoxide Production and Phagocytosis of Opsonized Particles
2004
Hematopoietic commitment during embryonic stem cell differentiation in culture.
1993
In Vivo Gene Delivery and Stable Transduction of Nondividing Cells by a Lentiviral Vector
1996 StandoutScience
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Osteoblasts and The Hematopoietic Microenvironment
1999
Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2009 StandoutScience
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Rac2 is critical for neutrophil primary granule exocytosis
2004
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Rac1 Deletion in Mouse Neutrophils Has Selective Effects on Neutrophil Functions
2003
Embryonic Stem Cell Lines Derived from Human Blastocysts
1998 StandoutScience
Rac GTPases regulate the morphology and deformability of the erythrocyte cytoskeleton
2006
Thrombocytosis in patients with tumors producing colony-stimulating factor
1992 StandoutNobel
Works of Daniel Williams being referenced
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency.
2000 StandoutNobel
Long-term expression of human adenosine deaminase in mice transplanted with retrovirus-infected hematopoietic stem cells.
1989
Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo.
1986
Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine.
1990
Support of human hematopoiesis in long-term bone marrow cultures by murine stromal cells selectively expressing the membrane-bound and secreted forms of the human homolog of the steel gene product, stem cell factor.
1992