Citation Impact
Citing Papers
Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors
2012
Reciprocal Regulation of DUSP9 and DUSP16 Expression by HIF1 Controls ERK and p38 MAP Kinase Activity and Mediates Chemotherapy-Induced Breast Cancer Stem Cell Enrichment
2018 StandoutNobel
Kinase-targeted cancer therapies: progress, challenges and future directions
2018
Bile acid–microbiota crosstalk in gastrointestinal inflammation and carcinogenesis
2017 Standout
Copper‐Catalyzed Oxidative Cross‐Coupling of Sulfoximines and Alkynes
2013
Sulfoximines: A Neglected Opportunity in Medicinal Chemistry
2013
Chemotherapy-Induced Ca2+ Release Stimulates Breast Cancer Stem Cell Enrichment
2017 StandoutNobel
Sulfoximines from a Medicinal Chemist's Perspective: Physicochemical and in vitro Parameters Relevant for Drug Discovery
2016
Mechanism-Based Inactivation (MBI) of Cytochrome P450 Enzymes: Structure–Activity Relationships and Discovery Strategies To Mitigate Drug–Drug Interaction Risks
2012
Computational Methods in Drug Discovery
2014
Redox catalysis in organic electrosynthesis: basic principles and recent developments
2014 Standout
Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’, ‘regulating’, and ‘locking’ the catalytic HNH domain
2018 StandoutNobel
The Role of Canalicular ABC Transporters in Cholestasis
2014
Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
2013 Standout
Targeting apoptosis in cancer therapy
2020 Standout
Drug discovery for a new generation of covalent drugs
2012
N‐Cyano Sulfoximines: COX Inhibition, Anticancer Activity, Cellular Toxicity, and Mutagenicity
2012
Lipoprotein Signal Peptidase Inhibitors with Antibiotic Properties Identified through Design of a Robust In Vitro HT Platform
2018
Riboswitch diversity and distribution
2017
Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy
2018 StandoutNobel
Chemical predictive modelling to improve compound quality
2013
Indoles as therapeutics of interest in medicinal chemistry: Bird's eye view
2017 Standout
SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules
2017 Standout
Strong coupling between surface plasmon polaritons and emitters: a review
2014 Standout
Covalent inhibitors in drug discovery: from accidental discoveries to avoided liabilities and designed therapies
2015
Using sulfuramidimidoyl fluorides that undergo sulfur(vi) fluoride exchange for inverse drug discovery
2020 StandoutNobel
Predicting drug metabolism: experiment and/or computation?
2015
Guidelines on the Use of Therapeutic Apheresis in Clinical Practice – Evidence‐Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue
2019 Standout
3d Transition Metals for C–H Activation
2018 Standout
Data-Mining for Sulfur and Fluorine: An Evaluation of Pharmaceuticals To Reveal Opportunities for Drug Design and Discovery
2013 Standout
Electrochemical synthesis of benzoxazoles mediated by 2,3-dichloro-5,6-dicyano-p-hydroquinone (DDH) as a redox catalyst
2016
pkCSM: Predicting Small-Molecule Pharmacokinetic and Toxicity Properties Using Graph-Based Signatures
2015 Standout
Computer Simulation of Liquids
2017 Standout
Characterization of a transcriptional TPP riboswitch in the human pathogen Neisseria meningitidis
2020 StandoutNobel
Mechanism of quinine-dependent monoclonal antibody binding to platelet glycoprotein IIb/IIIa
2015
Targeted Covalent Inhibitors for Drug Design
2016
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Light‐Induced Ruthenium‐Catalyzed Nitrene Transfer Reactions: A Photochemical Approach towards N‐Acyl Sulfimides and Sulfoximines
2014
Locally Weighted Learning Methods for Predicting Dose-Dependent Toxicity with Application to the Human Maximum Recommended Daily Dose
2012
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates
2018 StandoutNobel
Accessing Drug Metabolites via Transition‐Metal Catalyzed C−H Oxidation: The Liver as Synthetic Inspiration
2016
Metabolism and bioactivation of famitinib, a novel inhibitor of receptor tyrosine kinase, in cancer patients
2012
Molecular Docking and Structure-Based Drug Design Strategies
2015 Standout
Precise Modulation of CO2 Sorption in Ti8Ce2–Oxo Clusters: Elucidating Lewis Acidity of the Ce Metal Sites and Structural Flexibility
2024 StandoutNobel
Picomolar Inhibitors of HIV Reverse Transcriptase Featuring Bicyclic Replacement of a Cyanovinylphenyl Group
2013
Metabolism-guided drug design
2012
Enantioselective Imidation of Sulfides via Enzyme-Catalyzed Intermolecular Nitrogen-Atom Transfer
2014 StandoutNobel
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Finding the sweet spot: the role of nature and nurture in medicinal chemistry
2012
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
RNA Structural Dynamics As Captured by Molecular Simulations: A Comprehensive Overview
2018
Sulfoximine: Eine vernachlässigte Chance in der medizinischen Chemie
2013
Proteome-Wide Reactivity Profiling Identifies Diverse Carbamate Chemotypes Tuned for Serine Hydrolase Inhibition
2013
Synthetic Organic Electrochemical Methods Since 2000: On the Verge of a Renaissance
2017 Standout
Light‐Induced Ruthenium‐Catalyzed Nitrene Transfer Reactions: A Photochemical Approach towards N‐Acyl Sulfimides and Sulfoximines
2014
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Synthesis of Quinazolin-4(3H)-ones via Amidine N-Arylation
2013
Structural Modifications that Alter the P-Glycoprotein Efflux Properties of Compounds
2012
SuFEx Chemistry of Thionyl Tetrafluoride (SOF4) with Organolithium Nucleophiles: Synthesis of Sulfonimidoyl Fluorides, Sulfoximines, Sulfonimidamides, and Sulfonimidates
2018 StandoutNobel
A Heck–Matsuda Process for the Synthesis of β‐Arylethenesulfonyl Fluorides: Selectively Addressable Bis‐electrophiles for SuFEx Click Chemistry
2016 StandoutNobel
Rational Approaches to Improving Selectivity in Drug Design
2012
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
ADMETlab 2.0: an integrated online platform for accurate and comprehensive predictions of ADMET properties
2021 Standout
Biomedical Importance of Indoles
2013 Standout
Survey of the 2009 commercial optical biosensor literature
2011
Copper‐Catalyzed Direct Sulfoximination of Heteroaromatic N‐Oxides by Dual C−H/N−H Dehydrogenative Cross‐Coupling
2015
Transition Metal-Catalyzed C–H Amination: Scope, Mechanism, and Applications
2017 Standout
Arylfluorosulfates Inactivate Intracellular Lipid Binding Protein(s) through Chemoselective SuFEx Reaction with a Binding Site Tyr Residue
2016 StandoutNobel
Efficient Indirect Electrochemical Synthesis of 2‐Substituted Benzoxazoles using Sodium Iodide as Mediator
2013
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Computational Design of Cyclic Peptide Inhibitors of a Bacterial Membrane Lipoprotein Peptidase
2024 StandoutNobel
The Essential Medicinal Chemistry of Curcumin
2017 Standout
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
Works of Daniel P. Walker being referenced
Structural Characterization of Proline-rich Tyrosine Kinase 2 (PYK2) Reveals a Unique (DFG-out) Conformation and Enables Inhibitor Design
2009
Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity
2009
Synthesis and biological evaluation of substituted benzoxazoles as inhibitors of mPGES-1: Use of a conformation-based hypothesis to facilitate compound design
2012
Differences in CYP3A4 catalyzed bioactivation of 5-aminooxindole and 5-aminobenzsultam scaffolds in proline-rich tyrosine kinase 2 (PYK2) inhibitors: Retrospective analysis by CYP3A4 molecular docking, quantum chemical calculations and glutathione adduct detection using linear ion trap/orbitrap mass spectrometry
2009
A Practical Synthesis of 4-Amino-2-(Trifluoromethyl)nicotinic Acid
2010
Novel Riboswitch-Binding Flavin Analog That Protects Mice against Clostridium difficile Infection without Inhibiting Cecal Flora
2015
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
2011