Standout Papers
Citation Impact
Citing Papers
Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia
2013 StandoutNobel
MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice
2009 Science
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis
2012
Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD
2015
The EGLN-HIF O 2 -Sensing System: Multiple Inputs and Feedbacks
2017 StandoutNobel
Regulation of Type II Transmembrane Serine Proteinase TMPRSS6 by Hypoxia-inducible Factors
2010 StandoutNobel
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
A Knock-in Mouse Model of Human PHD2 Gene-associated Erythrocytosis Establishes a Haploinsufficiency Mechanism
2013
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
2015 StandoutNobel
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors
2010
Iron Metabolism: Interactions with Normal and Disordered Erythropoiesis
2012
Genome-Wide Association Studies in Nephrology Research
2010
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
2020 StandoutNobel
Targeting the hepcidin–ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation
2011
Retinopathy of prematurity
2013 Standout
Delivery materials for siRNA therapeutics
2013 Standout
Systemic VHL gene functions and the VHL disease
2012
Iron Deficiency and Raised Hepcidin in Idiopathic Pulmonary Arterial Hypertension
2011
Pegaptanib, a targeted anti-VEGF aptamer for ocular vascular disease
2006 Standout
Four-Week Studies of Oral Hypoxia-Inducible Factor–Prolyl Hydroxylase Inhibitor GSK1278863 for Treatment of Anemia
2015
HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond
2015
Chronic kidney disease
2011 Standout
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Minimizing the immunogenicity of protein therapeutics
2004
Erythropoietic drive is the strongest predictor of hepcidin level in adults with sickle cell disease
2015
Hepcidin and iron homeostasis
2012
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Erythrocytosis and Pulmonary Hypertension in a Mouse Model of Human HIF2A Gain of Function Mutation
2013
Development, maintenance and disruption of the blood-brain barrier
2013 Standout
Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization
2009
Revealing the human mucinome
2022 StandoutNobel
Identification of erythroferrone as an erythroid regulator of iron metabolism
2014
Iron regulation by hepcidin
2013
Glycosylation in health and disease
2019
Sickle-cell disease
2010 Standout
Iron deficiency in systemic sclerosis patients with and without pulmonary hypertension
2013
Promotion of airway anastomotic microvascular regeneration and alleviation of airway ischemia by deferoxamine nanoparticles
2013 StandoutNobel
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
Molecular Mechanisms of Hepcidin Regulation: Implications for the Anemia of CKD
2010
The physiological functions of iron regulatory proteins in iron homeostasis - an update
2014
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
The Pathobiology of Vascular Dementia
2013 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2
2013 StandoutNobel
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Unexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertension
2011
Chronic Kidney Disease
2016 Standout
Mediators involved in retinopathy of prematurity and emerging therapeutic targets
2011
Anemia of Chronic Disease
2005 Standout
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
2012 StandoutNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Iron Homeostasis and Its Interaction with Prolyl Hydroxylases
2009
The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice
2016
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Serum hepcidin: reference ranges and biochemical correlates in the general population
2011
Phenotypic Heterogeneity of the Endothelium
2007
Clinical iron deficiency disturbs normal human responses to hypoxia
2016 StandoutNobel
Regulation of hepcidin expression at high altitude
2011
The von Hippel-Lindau Chuvash mutation in mice causes carotid-body hyperplasia and enhanced ventilatory sensitivity to hypoxia
2013
Electron-Based Dissociation Is Needed for O-Glycopeptides Derived from OpeRATOR Proteolysis
2020 StandoutNobel
Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion
2014 StandoutNobel
Functional Nanomaterials for Phototherapies of Cancer
2014 Standout
Genetic and epigenetic factors influencing chronic kidney disease
2014
PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
2014 Standout
Contrasting effects of ascorbate and iron on the pulmonary vascular response to hypoxia in humans
2014
Iron, oxygen, and the pulmonary circulation
2015
Hepcidin and iron regulation, 10 years later
2011
Detection, evaluation, and management of iron-restricted erythropoiesis
2010
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Iron-Deficiency Anemia
2015 Standout
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
2015 StandoutNobel
HIF and pulmonary vascular responses to hypoxia
2013
Regulation of Hepcidin by Erythropoiesis: The Story So Far
2016
Cell-Specific Multifunctional Processing of Heterogeneous Cell Systems in a Single Laser Pulse Treatment
2012
Adaptation of iron requirement to hypoxic conditions at high altitude
2015
3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs
2014 Standout
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Treatment of erythropoietin deficiency in mice with systemically administered siRNA
2012 StandoutNobel
Recombinant immunotoxin for cancer treatment with low immunogenicity by identification and silencing of human T-cell epitopes
2014 StandoutNobel
Mutation of the gastric hydrogen-potassium ATPase alpha subunit causes iron-deficiency anemia in mice
2011 StandoutNobel
Inhibition of Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Oxygen Sensors: Tricking the Body into Mounting Orchestrated Survival and Repair Responses
2013
Works of Daniel P. Gale being referenced
Cardiopulmonary function in two human disorders of the hypoxia‐inducible factor (HIF) pathway: von Hippel‐Lindau disease and HIF‐2α gain‐of‐function mutation
2011 StandoutNobel
Familial C3 Glomerulopathy Associated with CFHR5 Mutations
2011
HLA Has Strongest Association with IgA Nephropathy in Genome-Wide Analysis
2010 StandoutNobel
Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease
2009
Evidence for a Lack of a Direct Transcriptional Suppression of the Iron Regulatory Peptide Hepcidin by Hypoxia-Inducible Factors
2009
Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin
2009
The role of HIF in immunity
2009
Variation in IGHMBP2 is not associated with IgA nephropathy in independent studies of UK Caucasian and Chinese Han patients
2009
Phenotypic heterogeneity is an evolutionarily conserved feature of the endothelium
2006
Defective angiogenesis, endothelial migration, proliferation, and MAPK signaling in Rap1b-deficient mice
2007
Galactosylation of IgA1 Is Associated with Common Variation in C1GALT1
2017
Development of a novel immunoassay for the iron regulatory peptide hepcidin
2009
Phase I evaluation of humanized OKT3: toxicity and immunomodulatory effects of hOKT3gamma4.
1999