Daniel O’Toole

Oxidative Stress

The gut microbiota influences blood-brain barrier permeability in mice

TEER Measurement Techniques for In Vitro Barrier Model Systems

Stem Cell Therapies in Clinical Trials: Progress and Challenges

Mitochondrial transfer from bone-marrow–derived stromal cells to pulmonary alveoli protects against acute lung injury

Chimeric antigen receptor-modified T cells for the immunotherapy of patients with EGFR-expressing advanced relapsed/refractory non-small cell lung cancer

Opioid-sparing Effects of a Low-dose Infusion of Naloxone in Patient-administered Morphine Sulfate 

Sepsis and septic shock

Acute respiratory distress syndrome

Regulation of intestinal epithelial permeability by tight junctions

Consensus Guidelines for the Management of Postoperative Nausea and Vomiting

Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis

Driving Pressure and Survival in the Acute Respiratory Distress Syndrome

Trends in drug delivery through tissue barriers containing tight junctions

Mechanical Ventilation–associated Lung Fibrosis in Acute Respiratory Distress Syndrome

Lactobacillus rhamnosus alleviates intestinal barrier dysfunction in part by increasing expression of zonula occludens-1 and myosin light-chain kinase in vivo

Ventilator-Induced Lung Injury

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

Elevated CO2 Levels Cause Mitochondrial Dysfunction and Impair Cell Proliferation

The immunopathology of sepsis and potential therapeutic targets

Endoscopic, Biopsy, and Histopathologic Guidelines for the Evaluation of Gastrointestinal Inflammation in Companion Animals

The acute respiratory distress syndrome

Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial

Distinct Risk Factor Profiles for Human Papillomavirus Type 16–Positive and Human Papillomavirus Type 16–Negative Head and Neck Cancers

Bacterial-mucosal interactions in inflammatory bowel disease—an alliance gone bad

F ifty Y ears of R esearch in ARDS.Cell-based Therapy for Acute Respiratory Distress Syndrome. Biology and Potential Therapeutic Value

Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response

The “Vertigo” of the Food Sector within the Triangle of Climate Change, the Post-Pandemic World, and the Russian-Ukrainian War

Upregulation of UCP2 Expression Protects against LPS-Induced Oxidative Stress and Apoptosis in Cardiomyocytes

Temperature corrected transepithelial electrical resistance (TEER) measurement to quantify rapid changes in paracellular permeability.

Targeting the CB₂receptor for immune modulation

Food Ingredients and Active Compounds against the Coronavirus Disease (COVID-19) Pandemic: A Comprehensive Review

The Chemistry of Reactive Oxygen Species (ROS) Revisited: Outlining Their Role in Biological Macromolecules (DNA, Lipids and Proteins) and Induced Pathologies

Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications

Nebulized Mesenchymal Stem Cell Derived Conditioned Medium Retains Antibacterial Properties Against Clinical Pathogen Isolates

Sepsis protects the myocardium and other organs from subsequent ischaemic/reperfusion injury via a MAPK-dependent mechanism

Lentiviral vector mediated modification of mesenchymal stem cells & enhanced survival in an in vitro model of ischaemia

The influence of naloxone infusion on the action of intrathecal diamorphine: low‐dose naloxone and neuroendocrine responses

Mesenchymal stromal cells are more effective than the MSC secretome in diminishing injury and enhancing recovery following ventilator-induced lung injury

β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects — Implications for coronavirus disease (COVID-19) immunotherapies

Therapeutic Efficacy of Human Mesenchymal Stromal Cells in the Repair of Established Ventilator-induced Lung Injury in the Rat

Cryopreserved, Xeno-Free Human Umbilical Cord Mesenchymal Stromal Cells Reduce Lung Injury Severity and Bacterial Burden in Rodent Escherichia coli–Induced Acute Respiratory Distress Syndrome

Myosin Light Chain Kinase Inhibition: Correction of Increased Intestinal Epithelial Permeability In Vitro

Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF- B dependent mechanism

Overexpression of pulmonary extracellular superoxide dismutase attenuates endotoxin-induced acute lung injury

Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat

The Synthetic Cannabinoid R(+)WIN 55,212-2 Inhibits the Interleukin-1 Signaling Pathway in Human Astrocytes in a Cannabinoid Receptor-independent Manner

Purified β‐glucans from the Shiitake mushroom ameliorates antibiotic‐resistant Klebsiella pneumoniae ‐induced pulmonary sepsis

Evolution of the Inflammatory and Fibroproliferative Responses during Resolution and Repair after Ventilator-induced Lung Injury in the Rat