Standout Papers
Citation Impact
Citing Papers
Atg7 Overcomes Senescence and Promotes Growth of Braf V600E-Driven Melanoma
2015
Galactose‐modified duocarmycin prodrugs as senolytics
2020
The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4
2015 Science
Senescent intimal foam cells are deleterious at all stages of atherosclerosis
2016 Science
Near-isotropic 3D optical nanoscopy with photon-limited chromophores
2010
BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance
2016
p21 maintains senescent cell viability under persistent DNA damage response by restraining JNK and caspase signaling
2017
Strategies for late phase preclinical and early clinical trials of senolytics
2021
Simvastatin suppresses breast cancer cell proliferation induced by senescent cells
2015
Recurrent turnover of senescent cells during regeneration of a complex structure
2015
p53 in Bronchial Club Cells Facilitates Chronic Lung Inflammation by Promoting Senescence
2018
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice
2023 StandoutNobel
Impaired immune surveillance accelerates accumulation of senescent cells and aging
2018
Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells
2018
Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
2016
Exosomes maintain cellular homeostasis by excreting harmful DNA from cells
2017
Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence
2015
Context-dependent effects of cellular senescence in cancer development
2016
The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
2022
The lncRNA MIR31HG regulates p16INK4A expression to modulate senescence
2015
The redox-senescence axis and its therapeutic targeting
2021
In vivo cyclic induction of the FOXM1 transcription factor delays natural and progeroid aging phenotypes and extends healthspan
2022
Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq
2016
An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
2014 Standout
Cellular Senescence Is Induced by the Environmental Neurotoxin Paraquat and Contributes to Neuropathology Linked to Parkinson’s Disease
2018
A proteomic atlas of senescence-associated secretomes for aging biomarker development
2020 Standout
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
2017
Injury-Induced Senescence Enables In Vivo Reprogramming in Skeletal Muscle
2016
Transforming Growth Factor-β Signaling in Immunity and Cancer
2019 Standout
Cellular senescence in aging and age-related disease: from mechanisms to therapy
2015 Standout
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
2015
Hallmarks of aging: An expanding universe
2023 Standout
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
Autophagy and senescence, converging roles in pathophysiology as seen through mouse models
2021
Long Noncoding RNAs in Cancer Pathways
2016 Standout
Senolytic activity of piperlongumine analogues: Synthesis and biological evaluation
2018
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis
2016
Hepatocellular carcinoma
2021 Standout
MLL1 is essential for the senescence-associated secretory phenotype
2016
Senescent cells: an emerging target for diseases of ageing
2017
LincRNA-p21 Activates p21 In cis to Promote Polycomb Target Gene Expression and to Enforce the G1/S Checkpoint
2014
Senolytic therapy alleviates Aβ-associated oligodendrocyte progenitor cell senescence and cognitive deficits in an Alzheimer’s disease model
2019
Ageing and the pathogenesis of osteoarthritis
2016
Corkscrew point spread function for far-field three-dimensional nanoscale localization of pointlike objects
2011 StandoutNobel
Sex differences in cancer mechanisms
2020
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The Structure and Function of Bacterial Actin Homologs
2010
Identification of senescent cell surface targetable protein DPP4
2017
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
NOTCH1 mediates a switch between two distinct secretomes during senescence
2016
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Forging a signature of in vivo senescence
2015
Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues
2020
Real-time imaging of senescence in tumors with DNA damage
2019
Macrophages in Tissue Repair, Regeneration, and Fibrosis
2016 Standout
TGF-β1 Signaling and Tissue Fibrosis
2017
Identification of HSP90 inhibitors as a novel class of senolytics
2017
Physiological and pathological consequences of cellular senescence
2014
From Ancient Pathways to Aging Cells—Connecting Metabolism and Cellular Senescence
2016
Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain
2020 StandoutNobel
Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
2013
Idiopathic pulmonary fibrosis
2017 Standout
Happily (n)ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
2016
Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage
2019 Standout
Classical and Nonclassical Intercellular Communication in Senescence and Ageing
2020
Exploring bacterial cell biology with single-molecule tracking and super-resolution imaging
2013 StandoutNobel
The evolving tumor microenvironment: From cancer initiation to metastatic outgrowth
2023 Standout
Defined p16High Senescent Cell Types Are Indispensable for Mouse Healthspan
2020
Therapeutic interventions for aging: the case of cellular senescence
2017
Autophagy maintains stemness by preventing senescence
2016 Nature
The senescence-associated secretory phenotype induces cellular plasticity and tissue regeneration
2017
Small extracellular vesicles secreted from senescent cells promote cancer cell proliferation through EphA2
2017
Macrophages as regulators of tumour immunity and immunotherapy
2019 Standout
Senescent cells communicate via intercellular protein transfer
2015
Hallmarks of Cellular Senescence
2018 Standout
Deregulated Expression of Mammalian lncRNA through Loss of SPT6 Induces R-Loop Formation, Replication Stress, and Cellular Senescence
2018
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
How the ageing microenvironment influences tumour progression
2019
The quest to slow ageing through drug discovery
2020
Senescent cell turnover slows with age providing an explanation for the Gompertz law
2019
Targeting autophagy in cancer
2017 Standout
SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells
2019
Chromosome organisation during ageing and senescence
2016
The role of telomeres and telomerase in cirrhosis and liver cancer
2019
Mitochondria as multifaceted regulators of cell death
2019 Standout
Of Flies, Mice, and Men: Evolutionarily Conserved Tissue Damage Responses and Aging
2015
The role of senescent cells in ageing
2014 StandoutNature
Do DNA Double-Strand Breaks Drive Aging?
2016
Breaking the Diffraction Barrier: Super-Resolution Imaging of Cells
2010 Standout
Senescence and the SASP: many therapeutic avenues
2020
A Phage Tubulin Assembles Dynamic Filaments by an Atypical Mechanism to Center Viral DNA within the Host Cell
2012
Unmasking Transcriptional Heterogeneity in Senescent Cells
2017
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Reassessment of Exosome Composition
2019 Standout
Osteoarthritis
2019 Standout
Tissue-Resident Macrophage Enhancer Landscapes Are Shaped by the Local Microenvironment
2014 Standout
The role of cellular senescence in cardiac disease: basic biology and clinical relevance
2021
Origin and Functions of Tissue Macrophages
2014
Cellular Senescence in Postmitotic Cells: Beyond Growth Arrest
2018
Unmasking senescence: context-dependent effects of SASP in cancer
2019
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Geroconversion of aged muscle stem cells under regenerative pressure
2014
p53 and the Carcinogenicity of Chronic Inflammation
2016
Embryogenesis and Adult Life in the Absence of Intrinsic Apoptosis Effectors BAX, BAK, and BOK
2018
The emerging role of senescent cells in tissue homeostasis and pathophysiology
2015
Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
2017
Senescence and apoptosis: dueling or complementary cell fates?
2014
Reactive Oxygen Species and Mitochondrial Homeostasis as Regulators of Stem Cell Fate and Function
2017
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene‐induced senescent cells
2015
HLA-G-mediated NK cell senescence promotes vascular remodeling: implications for reproduction
2014
Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape
2018
Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment
2018
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
Strategies targeting cellular senescence
2018
Molecular pathways of senescence regulate placental structure and function
2019
Correlative imaging of ionic transport and electronic structure in nano Li0.5FePO4 electrodes
2019 StandoutNobel
Analysis of individual cells identifies cell‐to‐cell variability following induction of cellular senescence
2017
Conserved and novel functions of programmed cellular senescence during vertebrate development
2016
Three-dimensional superresolution colocalization of intracellular protein superstructures and the cell surface in live Caulobacter crescentus
2011 StandoutNobel
Uncoupling the Senescence-Associated Secretory Phenotype from Cell Cycle Exit via Interleukin-1 Inactivation Unveils Its Protumorigenic Role
2019
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Quantitative identification of senescent cells in aging and disease
2017
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype
2019
Spermidine in health and disease
2018 StandoutScience
Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
2019
NKG2D ligands mediate immunosurveillance of senescent cells
2016
Knee osteoarthritis has doubled in prevalence since the mid-20th century
2017 Standout
TISIDB: an integrated repository portal for tumor–immune system interactions
2019 Standout
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Small molecule compounds that induce cellular senescence
2016
Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy
2016
Enzyme-Activated Fluorogenic Probes for Live-Cell and in Vivo Imaging
2018
Senescent cells and osteoarthritis: a painful connection
2018
Mouse Models to Disentangle the Hallmarks of Human Aging
2018
IPF lung fibroblasts have a senescent phenotype
2017
Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation
2019
Emerging roles of extracellular vesicles in cellular senescence and aging
2018
The chemistry of senescence
2019
Tissue damage and senescence provide critical signals for cellular reprogramming in vivo
2016 Science
A Fluorogenic Trehalose Probe for Tracking Phagocytosed Mycobacterium tuberculosis
2020 StandoutNobel
HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci
2016
The Bacterial Cytoskeleton
2010
Macrotheranostic Probe with Disease‐Activated Near‐Infrared Fluorescence, Photoacoustic, and Photothermal Signals for Imaging‐Guided Therapy
2018
Cell senescence contributes to tissue regeneration in zebrafish
2019
An early‐senescence state in aged mesenchymal stromal cells contributes to hematopoietic stem and progenitor cell clonogenic impairment through the activation of a pro‐inflammatory program
2019
Cellular senescence in development, regeneration and disease
2019
The ECM path of senescence in aging: components and modifiers
2020
Caenorhabditis elegans responses to bacteria from its natural habitats
2016 StandoutNobel
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
2020
Works of Daniel Muñoz‐Espín being referenced
Robust, universal biomarker assay to detect senescent cells in biological specimens
2016
Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3
2019
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
Cellular senescence: from physiology to pathology
2014 Standout
The actin-like MreB cytoskeleton organizes viral DNA replication in bacteria
2009
A versatile drug delivery system targeting senescent cells
2018
Galacto‐conjugation of Navitoclax as an efficient strategy to increase senolytic specificity and reduce platelet toxicity
2020
Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence
2018
An OFF–ON Two-Photon Fluorescent Probe for Tracking Cell Senescence in Vivo
2017
Targeting senescent cells in translational medicine
2019