Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
O-GlcNAc Transferase Integrates Metabolic Pathways to Regulate the Stability of c-MYC in Human Prostate Cancer Cells
2013
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
MYC Drives Pten/Trp53 -Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2
2015
Phthalimide conjugation as a strategy for in vivo target protein degradation
2015 Science
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Non-Cell-Autonomous Tumor Suppression by p53
2013
RNAi screening comes of age: improved techniques and complementary approaches
2014
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Mechanism and medical implications of mammalian autophagy
2018 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Regulation of microRNA biogenesis
2014 Standout
Bromodomain Protein BRD4 Is a Transcriptional Repressor of Autophagy and Lysosomal Function
2017
Targeting Epigenetic Readers in Cancer
2012
The microcosmos of cancer
2012 Nature
The emerging role of lncRNAs in cancer
2015 Standout
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
The biology and function of fibroblasts in cancer
2016 Standout
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Predicting outcomes in radiation oncology—multifactorial decision support systems
2012
The Human Transcription Factors
2018 Standout
Regulatory Enhancer–Core-Promoter Communication via Transcription Factors and Cofactors
2016
Cancer stem cells revisited
2017 Standout
An Optimized microRNA Backbone for Effective Single-Copy RNAi
2013
Epigenetics in Cancer: A Hematological Perspective
2016
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
2016 StandoutNobel
Metazoan MicroRNAs
2018 Standout
Targeting the IL-6/JAK/STAT3 signalling axis in cancer
2018 Standout
Stable RNA interference rules for silencing
2013
Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition
2013
Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy
2015
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Discovery of cancer drug targets by CRISPR-Cas9 screening of protein domains
2015
CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer
2015
EMT: 2016
2016 Standout
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
BET domain co-regulators in obesity, inflammation and cancer
2012
Histone Modifications and Cancer
2016
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
TGF-β Tumor Suppression through a Lethal EMT
2016
Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia
2012
Chromatin remodeller SMARCA4 recruits topoisomerase 1 and suppresses transcription-associated genomic instability
2016 StandoutNobel
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
The PI3K Pathway in Human Disease
2017 Standout
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Proto-Oncogenic Role of Mutant IDH2 in Leukemia Initiation and Maintenance
2014
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Decoding tumour phenotype by noninvasive imaging using a quantitative radiomics approach
2014 Standout
The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells
2012
MLL3 Is a Haploinsufficient 7q Tumor Suppressor in Acute Myeloid Leukemia
2014
Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting
2013
An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance
2011
Transcription control by the ENL YEATS domain in acute leukaemia
2017 Nature
An Argonaute phosphorylation cycle promotes microRNA-mediated silencing
2017 Nature
CRISPR/Cas9-Mediated Genome Editing of Epigenetic Factors for Cancer Therapy
2015
Acute Myeloid Leukemia
2015 Standout
A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes
2014 Science
Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma
2014
Identification of DNA cleavage- and recombination-specific hnRNP cofactors for activation-induced cytidine deaminase
2015 StandoutNobel
Systematic discovery of natural CRISPR-Cas12a inhibitors
2018 StandoutScienceNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis
2018 Science
BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
2012
Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis
2013
Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia
2013
Epigenetic plasticity: A central regulator of epithelial-to-mesenchymal transition in cancer
2014
DNA methylation in the central and efferent limbs of the chemoreflex requires carotid body neural activity
2017 StandoutNobel
Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers
2014
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Fluorosulfuryl Isocyanate Enabled SuFEx Ligation of Alcohols and Amines
2021 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Chemical Inhibition of ENL/AF9 YEATS Domains in Acute Leukemia
2021 StandoutNobel
Genetics and biology of pancreatic ductal adenocarcinoma
2016
APE1 is dispensable for S-region cleavage but required for its repair in class switch recombination
2014 StandoutNobel
Works of Daniel Magoon being referenced
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease
2013
A phase 1 dosing study of ruxolitinib in children with relapsed or refractory solid tumors, leukemias, or myeloproliferative neoplasms: A Children's Oncology Group phase 1 consortium study (ADVL1011)
2015