Standout Papers
Citation Impact
Citing Papers
Combining Betulinic Acid and Mithramycin A Effectively Suppresses Pancreatic Cancer by Inhibiting Proliferation, Invasion, and Angiogenesis
2011
Reactive Oxygen Species in Inflammation and Tissue Injury
2013 Standout
Effect of Betulinic Acid on Anticancer Drug‐Resistant Colon Cancer Cells
2007
Synergy-Directed Fractionation of Botanical Medicines: A Case Study with Goldenseal (Hydrastis canadensis)
2011
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Recent Advances in the Discovery and Development of Flavonoids and their Analogues as Antitumor and Anti-HIV Agents
1998
Exploring Cancer Therapeutics with Natural Products from African Medicinal Plants, Part II: Alkaloids, Terpenoids and Flavonoids
2015
Features of the dendritic cell lineage
2010 StandoutNobel
Active immunization against cancer with dendritic cells: The near future
2001 StandoutNobel
High-performance liquid chromatography—Two wavelength detection of triterpenoid acids from the fruits of Ziziphus jujuba containing various cultivars in different regions and classification using chemometric analysis
2009
Marine natural products
1990 Standout
Legumes and soybeans: overview of their nutritional profiles and health effects
1999 Standout
The use of dendritic cells in cancer immunotherapy
2003 StandoutNobel
Curcumin as “Curecumin”: From kitchen to clinic
2007 Standout
p53-Independent Upregulation of KILLER/DR5 TRAIL Receptor Expression by Glucocorticoids and Interferon-γ
2001
Nano based drug delivery systems: recent developments and future prospects
2018 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Betulinic acid: A new cytotoxic agent against malignant brain-tumor cells
1999
Betulinic acid prevention of d -galactosamine/lipopolysaccharide liver toxicity is triggered by activation of Bcl-2 and antioxidant mechanisms
2011
Betulinic acid induces apoptosis through a direct effect on mitochondria in neuroectodermal tumors
2000
Extraction of Plant Secondary Metabolites
2012
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
New Approaches and Therapeutics Targeting Apoptosis in Disease
2005
Mitochondrial control of cell death
2000 Standout
The biochemistry and medical significance of the flavonoids
2002 Standout
Apoptosis Induction in HL-60 Cells and Inhibition of Topoisomerase II by Triterpene Celastrol
2003
Flavonoids: a review of probable mechanisms of action and potential applications
2001 Standout
Caspase Functions in Cell Death and Disease
2013 Standout
The synergistic effects of betulin with acyclovir against herpes simplex viruses
2004
Mitochondria: pharmacological manipulation of cell death
2005
Isolation and characterization of bioactive compounds from plant resources: The role of analysis in the ethnopharmacological approach
2013
Inhibition of growth and induction of differentiation of metastatic melanoma cells in vitro by genistein: chemosensitivity is regulated by cellular p53
1997
Flavonoid antioxidants: chemistry, metabolism and structure-activity relationships
2002 Standout
Effects of Betulinic Acid Alone and in Combination with Irradiation in Human Melanoma Cells
2000
Advances in flavonoid research since 1992
2000 Standout
Natural Product Hybrids as New Leads for Drug Discovery
2003 Standout
Plant Polyphenols: Chemical Properties, Biological Activities, and Synthesis
2011 Standout
Pharmacological properties of the ubiquitous natural product betulin
2006
Mitochondrial Membrane Permeabilization in Cell Death
2007 Standout
Acetyl-Boswellic Acids Are Novel Catalytic Inhibitors of Human Topoisomerases I and IIα
2000
The Chemistry of Wine Polyphenolic C‐Glycosidic Ellagitannins Targeting Human Topoisomerase II
2005
Apoptolidin: Induction of Apoptosis by a Natural Product
2006
Biosynthesis of plant pigments: anthocyanins, betalains and carotenoids
2008 Standout
Betulinic acid induces apoptosis in human neuroblastoma cell lines
1997
Drug discovery from medicinal plants
2005 Standout
Biodiversity and drug discovery — a symbiotic relationship
2000
Cytotoxic biflavonoids from Selaginella willdenowii
1995
Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid
1998
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer
2007
Theoretical Basis, Experimental Design, and Computerized Simulation of Synergism and Antagonism in Drug Combination Studies
2006 Standout
Discovery and resupply of pharmacologically active plant-derived natural products: A review
2015 Standout
Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy
2006 Standout
Inhibition of tumour cell growth by hyperforin, a novel anticancer drug from St. John's wort that acts by induction of apoptosis
2002
Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells
2002 Standout
Cell death mechanisms of plant-derived anticancer drugs: beyond apoptosis
2015
Cross-Priming of Naive Cd8 T Cells against Melanoma Antigens Using Dendritic Cells Loaded with Killed Allogeneic Melanoma Cells
2000
Constituents from Salvia Species and Their Biological Activities
2012 Standout
Natural Products as a Foundation for Drug Discovery
2009
Role of Nrf2 in Oxidative Stress and Toxicity
2013 Standout
Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice
2006 Standout
Samarium(II)-Iodide-Mediated Cyclizations in Natural Product Synthesis
2004 Standout
Bioactive Triterpenoids from Salvia Species
2006
Effect of berberine on proliferation, cell cycle and apoptosis in HeLa and L1210 cells
2003
Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant States
2006 Standout
Betulinic Acid: Recent Advances in Chemical Modifications, Effective Delivery, and Molecular Mechanisms of a Promising Anticancer Therapy
2015
Preparation of a 24-Nor-1,4-dien-3-one Triterpene Derivative from Betulin: A New Route to 24-Nortriterpene Analogues1
2002
The Relevance of Higher Plants in Lead Compound Discovery Programs
2011
Betulinic acid prevents alcohol-induced liver damage by improving the antioxidant system in mice
2014
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
The Herbal DrugMelampyrum pratenseL. (Koch): Isolation and Identification of Its Bioactive Compounds Targeting Mediators of Inflammation
2013
Betulinic Acid and its Derivatives as Potential Antitumor Agents
2015
Polycyclic Polyprenylated Acylphloroglucinols
2006 Standout
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Anticancer activity of natural and synthetic acetylenic lipids
2006
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Reengineering Antibiotics to Combat Bacterial Resistance: Click Chemistry [1,2,3]‐Triazole Vancomycin Dimers with Potent Activity against MRSA and VRE
2016 StandoutNobel
Betulinic Acid-Mediated Apoptosis in Human Prostate Cancer Cells Involves p53 and Nuclear Factor-Kappa B (NF-κB) Pathways
2017
An Updated Review of Tyrosinase Inhibitors
2009 Standout
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Dendritic Cells Charged with Apoptotic Tumor Cells Induce Long-Lived Protective CD4+ and CD8+ T Cell Immunity against B16 Melanoma
2003 StandoutNobel
The Role of Oxidative Stress and Antioxidants in Liver Diseases
2015 Standout
Recent Advances in Efficient and Selective Synthesis of Di-, Tri-, and Tetrasubstituted Alkenes via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy
2008 StandoutNobel
Selective Oxidation of Betulin for the Preparation of Betulinic Acid, an Antitumoral Compound
2004
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone
2010 Standout
Chemical studies of anthocyanins: A review
2008 Standout
The Jujube (Ziziphus Jujuba Mill.) Fruit: A Review of Current Knowledge of Fruit Composition and Health Benefits
2013 Standout
THE GENETICS AND BIOCHEMISTRY OF FLORAL PIGMENTS
2006 Standout
Plant Secondary Metabolites as Anticancer Agents: Successes in Clinical Trials and Therapeutic Application
2018 Standout
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
Betulinic Acid-Induced Apoptosis in Glioma Cells: A Sequential Requirement for New Protein Synthesis, Formation of Reactive Oxygen Species, and Caspase Processing
1999
Tolerogenic Dendritic Cells
2003 StandoutNobel
Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery
2018
Modern Natural Products Drug Discovery and Its Relevance to Biodiversity Conservation
2010
Betulinic Acid Inhibits Prostate Cancer Growth through Inhibition of Specificity Protein Transcription Factors
2007
Antineoplastic agents from natural sources: achievements and future directions
2000
Natural-product inhibitors of human DNA ligase I
1996
Works of Daniel M. Brown being referenced
Isolation and Structure Identification of an Active DNA Strand-Scission Agent, (+)-3,4-di-hydroxy-8,9-Methylenedioxypterocarpan
1995
Effect of tannins on screening of plant extracts for enzyme inhibitory activity and techniques for their removal
1996
Discovery of betulinic acid as a selective inhibitor of human melanoma that functions by induction of apoptosis
1995 Standout
Isolation and Structural Elucidation of Pentacyclic Triterpenoids from Maprounea africana
1995
Plant Antitumor Agents. 31.1 The Calycopterones, a New Class of Biflavonoids with Novel Cytotoxicity in a Diverse Panel of Human Tumor Cell Lines
1994
Gummiferol, a Cytotoxic Polyacetylene from the Leaves of Adenia gummifera
1995
ChemInform Abstract: Plant Antitumor Agents. Part 31. The Calycopterones, a New Class of Biflavonoids with Novel Cytotoxicity in a Diverse Panel of Human Tumor Cell Lines.
1994