Citation Impact
Citing Papers
Comprehensive computational design of ordered peptide macrocycles
2017 StandoutScienceNobel
Property‐Driven Development of Passively Permeable Macrocyclic Scaffolds Using Heterocycles**
2022
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Catalytic Asymmetric Three‐Component Synthesis of Homoallylic Amines
2013 StandoutNobel
Acromegaly
2006 Standout
Recent advances in the catalytic asymmetric synthesis of β-amino acids
2010 StandoutNobel
Ga-66 labeled somatostatin analogue DOTA-DPhe 1 -Tyr 3 -octreotide as a potential agent for positron emission tomography imaging and receptor mediated internal radiotherapy of somatostatin receptor positive tumors
2002
Regio‐ and Enantioselective Aminofluorination of Alkenes
2013
Rethinking amide bond synthesis
2011 StandoutNature
Design and properties of functional nanotubes from the self-assembly of cyclic peptide templates
2012
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Cushing's syndrome
2015 Standout
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
Natural Product-Like Macrocyclic N-Methyl-Peptide Inhibitors against a Ubiquitin Ligase Uncovered from a Ribosome-Expressed De Novo Library
2011
Vertebrate Smoothened functions at the primary cilium
2005 StandoutNature
Synthesis and biological investigations of dopaminergic partial agonists preferentially recognizing the D4 receptor subtype
2006
Selective targeting of somatostatin receptor 3 to neuronal cilia
1999
Targeting protein–protein interactions: Lessons from p53/MDM2
2007
Functional role of TRPC channels in the regulation of endothelial permeability
2005
Foldamers as versatile frameworks for the design and evolution of function
2007
Probing the Bioactive Conformation of an Archetypal Natural Product HDAC Inhibitor with Conformationally Homogeneous Triazole‐Modified Cyclic Tetrapeptides
2009
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Opportunities in somatostatin research: biological, chemical and therapeutic aspects
2003
Direct Electrophilic N‐Trifluoromethylation of Azoles by a Hypervalent Iodine Reagent
2012
The World of β‐ and γ‐Peptides Comprised of Homologated Proteinogenic Amino Acids and Other Components
2004
Conformationally Homogeneous Heterocyclic Pseudotetrapeptides as Three‐Dimensional Scaffolds for Rational Drug Design: Receptor‐Selective Somatostatin Analogues
2009
Mechanism‐Inspired Engineering of Phenylalanine Aminomutase for Enhanced β‐Regioselective Asymmetric Amination of Cinnamates
2011 StandoutNobel
The Future of Peptide‐based Drugs
2012 Standout
Probing the interactions of an acyl carrier protein domain from the 6‐deoxyerythronolide B synthase
2011
The Cross‐Dehydrogenative Coupling of CH Bonds: A Versatile Strategy for CC Bond Formations
2013 Standout
Dopaminergic Supersensitivity in G Protein-Coupled Receptor Kinase 6-Deficient Mice
2003 StandoutNobel
Cushing's syndrome
2006 Standout
Transient Receptor Potential Cation Channels in Disease
2007 Standout
Peptidic foldamers: ramping up diversity
2011
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
β2‐amino acids—syntheses, occurrence in natural products, and components of β‐peptides1,2
2004
The multi-ligand somatostatin analogue SOM230 inhibits ACTH secretion by cultured human corticotroph adenomas via somatostatin receptor type 5
2005
Autoxidative Carbon–Carbon Bond Formation from Carbon–Hydrogen Bonds
2010
Imaging analysis of clock neurons reveals light buffers the wake-promoting effect of dopamine
2011 StandoutNobel
Trends in peptide drug discovery
2021
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Orally Absorbed Cyclic Peptides
2017
3d Transition Metals for C–H Activation
2018 Standout
Fluorine in medicinal chemistry
2007 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Templated scaffolds of cis- and trans-tetrahydrofuran γ-amino acids: γ-azido-β-hydroxy-tetrahydrofuran-2-carboxylates from pentono-δ-lactones
2003
Emerging Methods and Design Principles for Cell‐Penetrant Peptides
2018
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
The Catalytic Asymmetric Mukaiyama–Michael Reaction of Silyl Ketene Acetals with α,β‐Unsaturated Methyl Esters
2017 StandoutNobel
Oxidative Coupling between Two Hydrocarbons: An Update of Recent C–H Functionalizations
2015 Standout
Distribution of G-protein-coupled receptor kinase (GRK) isoforms 2, 3, 5 and 6 mRNA in the rat brain
2001
Design and Development of a Cyclic Decapeptide Scaffold with Suitable Properties for Bioavailability and Oral Exposure
2016
Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges
2019
Palladium-Catalyzed Anti-Markovnikov Oxidation of Allylic Amides to Protected β-Amino Aldehydes
2014 StandoutNobel
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Understanding Cell Penetration of Cyclic Peptides
2019
Direkte elektrophile N‐Trifluormethylierung von Azolen mit einem hypervalenten Iodreagens
2012
Folding of Oligoviologens Induced by Radical–Radical Interactions
2014 StandoutNobel
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
β-Peptidic Peptidomimetics
2008
Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents
2014 Standout
Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1
2021 StandoutNobel
Biochemical Properties and Crystal Structure of a β-Phenylalanine Aminotransferase from Variovorax paradoxus
2012 StandoutNobel
Supramolecular Helical Systems: Helical Assemblies of Small Molecules, Foldamers, and Polymers with Chiral Amplification and Their Functions
2016 Standout
Catalytic Asymmetric Synthesis of Unprotected β2-Amino Acids
2021 StandoutNobel
Current and Novel Approaches to the Drug Treatment of Schizophrenia
2001
Helical Polymers: Synthesis, Structures, and Functions
2009 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Dual Catalysis Strategies in Photochemical Synthesis
2016 Standout
N-Methylation of Peptides: A New Perspective in Medicinal Chemistry
2008
Electrophilic S‐Trifluoromethylation of Cysteine Side Chains in α‐ and β‐Peptides: Isolation of Trifluoro‐methylated Sandostatin® (Octreotide) Derivatives
2008
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Disulfonimide-Catalyzed Asymmetric Synthesis of β3-Amino Esters Directly from N-Boc-Amino Sulfones
2013 StandoutNobel
Organocatalytic Asymmetric Transferhydrogenation of β-Nitroacrylates: Accessing β2-Amino Acids
2008 StandoutNobel
DESENSITIZATION OF G PROTEIN–COUPLED RECEPTORS AND NEURONAL FUNCTIONS
2004 StandoutNobel
De Novo Carborane-Containing Macrocyclic Peptides Targeting Human Epidermal Growth Factor Receptor
2019 StandoutNobel
Conformational Effects on the Passive Membrane Permeability of Synthetic Macrocycles
2022
Enantioselective Direct α-Amination of Aldehydes via a Photoredox Mechanism: A Strategy for Asymmetric Amine Fragment Coupling
2013
Autoxidative Bildung von Kohlenstoff‐Kohlenstoff‐Bindungen aus Kohlenstoff‐Wasserstoff‐Bindungen
2010
Cyclic peptide oral bioavailability: Lessons from the past
2016
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
How we drifted into peptide chemistry and where we have arrived at
2004
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants
2002
Synthesis, Structure and Conformation of Partially‐Modified Retro‐ and Retro‐Inverso ψ[NHCH(CF3)]Gly Peptides
2003
Aldehyde Selective Wacker Oxidations of Phthalimide Protected Allylic Amines: A New Catalytic Route to β3-Amino Acids
2009 StandoutNobel
Conformational Strain of Macrocyclic Peptides in Ligand–Receptor Complexes Based on Advanced Refinement of Bound-State Conformers
2021
Cyanoindole Derivatives as Highly Selective Dopamine D4Receptor Partial Agonists: Solid-Phase Synthesis, Binding Assays, and Functional Experiments
2000
Organocatalytic Enantioselective Olefin Aminofluorination
2010
Differential Effects of β3‐ versus β2‐Amino Acid Residues on the Helicity and Recognition Properties of Bim BH3‐Derived α/β‐Peptides
2018
Cyclic Tetrapeptides from Nature and Design: A Review of Synthetic Methodologies, Structure, and Function
2019
Sulfonic Acid‐Catalyzed Autoxidative Carbon‐Carbon Coupling Reaction under Elevated Partial Pressure of Oxygen
2012
Structural Chemistry of Peptides Containing Backbone Expanded Amino Acid Residues: Conformational Features of β, γ, and Hybrid Peptides
2010
Peptide Receptors as Molecular Targets for Cancer Diagnosis and Therapy
2003
Works of Daniel Langenegger being referenced
β2/β3-di- and α/β3-tetrapeptide derivatives as potent agonists at somatostatin sst4 receptors
2003
Improving Oral Bioavailability of Peptides by Multiple N‐Methylation: Somatostatin Analogues
2008
Distribution and characterisation of somatostatin receptor mRNA and binding sites in the brain and periphery
2000
Characterization and distribution of somatostatin SS-1 and SRIF-1 binding sites in rat brain: identitity with SSTR-2 receptors
1995
Functional characterisation of the putative somatostatin sst2 receptor antagonist CYN 154806
2003
Cloning, expression and pharmacological characterisation of the mouse somatostatin sst5 receptor
2000
Receptor density as a factor governing the efficacy of the dopamine D4 receptor ligands, L‐745,870 and U‐101958 at human recombinant D4.4 receptors expressed in CHO cells
1999
The Enantiomer of Octreotate Binds to All Five Somatostatin Receptors with Almost Equal Micromolar Affinity – A Comparison with SANDOSTATIN®
2008
Lack of evidence for cross-competition between vasoactive intestinal peptide and somatostatin at their respective receptors
2001
Pharmacological characterisation of native somatostatin receptors in AtT‐20 mouse tumour corticotrophs
2003
Discovery of novel non-peptidic β-alanine piperazine amide derivatives and their optimization to achiral, easily accessible, potent and selective somatostatin sst1 receptor antagonists
2009
NMR‐Solution Structures and Affinities for the Human Somatostatin G‐Protein‐Coupled Receptors hsst1–5 of CF3 Derivatives of Sandostatin® (Octreotide)
2009
Die Verbesserung der oralen Bioverfügbarkeit von Peptiden durch multiple N‐Methylierung: Somatostatin‐Analoga
2008
Linear, Peptidase-Resistantβ2/β3-Di- andα/β3-Tetrapeptide Derivatives with Nanomolar Affinities to a Human Somatostatin Receptor, Preliminary Communication
2001
New Open‐Chain and Cyclic Tetrapeptides, Consisting of α‐, β2‐, and β3‐Amino‐Acid Residues, as Somatostatin Mimics – A Survey
2008