Citation Impact
Citing Papers
2014
Developmental Decline in Neuronal Regeneration by the Progressive Change of Two Intrinsic Timers
2013 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses
2006
The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
2013 StandoutScienceNobel
Caspase-mediated processing of the Drosophila NF-κB factor Relish
2003
A Dual Role for IKK a in Tooth Development
2003
Signalling and survival pathways in multiple myeloma
2006
Her-2/neu overexpression induces NF-κB via a PI3-kinase/Akt pathway involving calpain-mediated degradation of IκB-α that can be inhibited by the tumor suppressor PTEN
2001
Protein Phosphatase 2A Enables Expression of Interleukin 17 (IL-17) through Chromatin Remodeling
2013
Acetylation of Stat1 modulates NF-κB activity
2006
Activators and target genes of Rel/NF-κB transcription factors
1999 Standout
Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway
2006
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
2006
Mutations in the NF-κB signaling pathway: implications for human disease
2006
The NEDD8 Pathway Is Essential for SCFβ-TrCP-mediated Ubiquitination and Processing of the NF-κB Precursor p105
2002 StandoutNobel
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
2013
Elongator stabilizes microtubules to control central spindle asymmetry and polarized trafficking of cell fate determinants
2022
Heritability of nociception. III. Genetic relationships among commonly used assays of nociception and hypersensitivity
2002
Regulation of microRNA biogenesis
2014 Standout
The IKK/NF-κB activation pathway—a target for prevention and treatment of cancer
2003
NF-κB in cancer: from innocent bystander to major culprit
2002 Standout
Nuclear Role of IκB Kinase-γ/NF-κB Essential Modulator (IKKγ/NEMO) in NF-κB-dependent Gene Expression
2004
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
2014
Shared Principles in NF-κB Signaling
2008 Standout
Constructing and Deconstructing Stem Cell Models of Neurological Disease
2011
A Dual Role for Ikkα in Tooth Development
2004
Ca2+-free Calmodulin and Calmodulin Damaged byin Vitro Aging Are Selectively Degraded by 26 S Proteasomes without Ubiquitination
2000
Parkin and mitochondrial quality control: toward assembling the puzzle
2014
NF-κB, the first quarter-century: remarkable progress and outstanding questions
2012 Standout
TRAP1 rescues PINK1 loss-of-function phenotypes
2013
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
Selective activation of NF-κB subunits in human breast cancer: potential roles for NF-κB2/p52 and for Bcl-3
2000
Inhibition of Interleukin-1-stimulated NF-κB RelA/p65 Phosphorylation by Mesalamine Is Accompanied by Decreased Transcriptional Activity
1999
Inflammation, stress, and diabetes
2005 Standout
Transfection of a dominant-negative mutant NF-kB inhibitor (IkBm) represses p53-dependent apoptosis in acute lymphoblastic leukemia cells: interaction of IkBm and p53
2003
Retroviral oncoprotein Tax induces processing of NF-kappaB2/p100 in T cells: evidence for the involvement of IKKalpha
2001
Recruitment of a ROC1–CUL1 Ubiquitin Ligase by Skp1 and HOS to Catalyze the Ubiquitination of IκBα
1999
To be, or not to be: NF-κB is the answer – role of Rel/NF-κB in the regulation of apoptosis
2003
A minimal glycine-alanine repeat prevents the interaction of ubiquitinated IκBα with the proteasome: a new mechanism for selective inhibition of proteolysis
1998
c‐Rel is crucial for the induction of Foxp3+ regulatory CD4+ T cells but not TH17 cells
2010
Receptor-Specific Signaling for Both the Alternative and the Canonical NF-κB Activation Pathways by NF-κB-Inducing Kinase
2004
Argonaute proteins: functional insights and emerging roles
2013
Loss-of-Function of Human PINK1 Results in Mitochondrial Pathology and Can Be Rescued by Parkin
2007
The SCFbeta -TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in Ikappa Balpha and beta -catenin and stimulates Ikappa Balpha ubiquitination in vitro
1999
Activation of NF-kappaB/Rel occurs early during neoplastic transformation of mammary cells
2000
Processing of p105 Is Inhibited by Docking of p50 Active Subunits to the Ankyrin Repeat Domain, and Inhibition Is Alleviated by Signaling via the Carboxyl-terminal Phosphorylation/ Ubiquitin-Ligase Binding Domain
2001 StandoutNobel
Parkin Interacts with Ambra1 to Induce Mitophagy
2011
Müllerian Inhibiting Substance Inhibits Breast Cancer Cell Growth through an NFκB-mediated Pathway
2000
Piezo2 is the major transducer of mechanical forces for touch sensation in mice
2014 StandoutNatureNobel
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
The two NF-κB activation pathways and their role in innate and adaptive immunity
2004 Standout
NF-κB and IKK as therapeutic targets in cancer
2006 Standout
Expression of the NF-κB target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells
2001
The immune response of Drosophila
2003 StandoutNatureNobel
Cyld Inhibits Tumor Cell Proliferation by Blocking Bcl-3-Dependent NF-κB Signaling
2006
Nuclear factor-?B: its role in health and disease
2004
kin-19/casein kinase Iαhas dual functions in regulating asymmetric division and terminal differentiation inC. elegansepidermal stem cells
2010
NF-kappa B p105 is a target of Ikappa B kinases and controls signal induction of Bcl-3-p50 complexes
1999
PINK1 Triggers Autocatalytic Activation of Parkin to Specify Cell Fate Decisions
2014
The Role of Epstein-Barr Virus in Neoplastic Transformation
2001
IKKβ and Phosphatidylinositol 3-Kinase/Akt Participate in Non-pathogenic Gram-negative Enteric Bacteria-induced RelA Phosphorylation and NF-κB Activation in Both Primary and Intestinal Epithelial Cell Lines
2002
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants
2014
Functional interplay between Parkin and Drp1 in mitochondrial fission and clearance
2014
RNA-binding proteins in human genetic disease
2020
Signaling to NF-κB
2004 Standout
Nuclear factor-κB is upregulated in colorectal cancer
2001
The evolution and genetics of innate immunity
2001 StandoutNobel
The Bcl-3 oncoprotein acts as a bridging factor between NF-κB/Rel and nuclear co-regulators
1999
Proteolysis of NF-κB1 p105 is essential for T cell antigen receptor–induced proliferation
2008
IKKα Provides an Essential Link between RANK Signaling and Cyclin D1 Expression during Mammary Gland Development
2001
Cancer-related inflammation
2008 StandoutNature
Antimicrobial peptides of multicellular organisms
2002 StandoutNature
A requirement for NF-kappa B activation in Bcr-Abl-mediated transformation
1998
NF-κB is a target of AKT in anti-apoptotic PDGF signalling
1999 StandoutNature
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
2009 Nature
Good cop, bad cop: the different faces of NF-κB
2006
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Caenorhabditis elegans as a model for stem cell biology
2010
INK4 cell cycle inhibitors direct transcriptional inactivation of NF-κB
1999
Structure of the human Parkin ligase domain in an autoinhibited state
2013
Integrating cell-signalling pathways with NF-κB and IKK function
2006 Standout
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
A mutation of Ikbkg causes immune deficiency without impairing degradation of IκBα
2010 StandoutNobel
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes
2001
The nuclear factor kappa B (NF-κB): A potential therapeutic target for estrogen receptor negative breast cancers
2001
Regulation and Function of NF-κB Transcription Factors in the Immune System
2009 Standout
Signal perception and transduction in plant defense responses.
1997
Rbx1, a Component of the VHL Tumor Suppressor Complex and SCF Ubiquitin Ligase
1999 StandoutScienceNobel
Mixed-Lineage Kinase 3 Delivers CD3/CD28-Derived Signals into the IκB Kinase Complex
2000
Viral evasion and subversion of pattern-recognition receptor signalling
2008
Dephosphorylation Targets Bcl-2 for Ubiquitin-dependent Degradation: A Link between the Apoptosome and the Proteasome Pathway
1999
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Cellular and molecular mechanisms in cancer immune escape: a comprehensive review
2013
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Two distinctive pathways for recruitment of naïve and primed IgM+B cells to the gut lamina propria
2005 StandoutNobel
Modulation of NF-κB Activity and Apoptosis in Chronic Lymphocytic Leukemia B Cells
2000
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
IκB Kinase Is an Essential Component of the Tpl2 Signaling Pathway
2004
Lipopolysaccharide Activation of the TPL-2/MEK/Extracellular Signal-Regulated Kinase Mitogen-Activated Protein Kinase Cascade Is Regulated by IκB Kinase-Induced Proteolysis of NF-κB1 p105
2004
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Proteasomes in the archaea: from structure to function
2000
Requirement of NF-κB/Rel for the development of hair follicles and other epidermal appendices
2001
Regulation of apoptosis by the circadian clock through NF-κB signaling
2011 StandoutNobel
Genome-Wide Analysis of Gene Expression in T Cells to Identify Targets of the NF-κB Transcription Factor c-Rel
2007
A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits
1998
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Transcriptional Cross Talk between NF-κB and p53
1999
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Dual Effects of IκB Kinase β-Mediated Phosphorylation on p105 Fate: SCFβ-TrCP-Dependent Degradation and SCFβ-TrCP-Independent Processing
2003 StandoutNobel
NF-κB Controls Cell Growth and Differentiation through Transcriptional Regulation of Cyclin D1
1999
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Roles of IKK kinases and protein kinase CK2 in activation of nuclear factor-kappaB in breast cancer.
2001
MyD88 signaling in nonhematopoietic cells protects mice against induced colitis by regulating specific EGF receptor ligands
2010 StandoutNobel
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
2003
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
βTrCP-Mediated Proteolysis of NF-κB1 p105 Requires Phosphorylation of p105 Serines 927 and 932
2002
The Interplay between the Glucocorticoid Receptor and Nuclear Factor-κB or Activator Protein-1: Molecular Mechanisms for Gene Repression
2003
Lenalidomide efficacy in activated B ‐cell‐like subtype diffuse large B ‐cell lymphoma is dependent upon IRF 4 and cereblon expression
2012
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
The Putative Oncoprotein Bcl-3 Induces Cyclin D1 To Stimulate G1 Transition
2001
Works of Daniel Krappmann being referenced
The let-7 target gene mouse lin-41 is a stem cell specific E3 ubiquitin ligase for the miRNA pathway protein Ago2
2009
Parkin Mediates Neuroprotection through Activation of IκB Kinase/Nuclear Factor-κB Signaling
2007
Purification and Characterization of the Human Elongator Complex
2002
The NF-κB/Rel and IκB gene families: mediators of immune response and inflammation
1996
The IκB Kinase (IKK) Complex Is Tripartite and Contains IKKγ but Not IKAP as a Regular Component
2000
Constitutive nuclear factor-kappaB-RelA activation is required for proliferation and survival of Hodgkin's disease tumor cells.
1997
The E3 Ligase Parkin Maintains Mitochondrial Integrity by Increasing Linear Ubiquitination of NEMO
2013
NF-κB and the innate immune response
2000
Essential Role for IκB Kinase β in Remodeling Carma1-Bcl10-Malt1 Complexes upon T Cell Activation
2006
Malt1 ubiquitination triggers NF‐κB signaling upon T‐cell activation
2007
MALT1 directs B cell receptor–induced canonical nuclear factor-κB signaling selectively to the c-Rel subunit
2007
Dephosphorylation of Carma1 by PP2A negatively regulates T‐cell activation
2010
Molecular mechanisms of constitutive NF-κB/Rel activation in Hodgkin/Reed-Sternberg cells
1999
Tissue-Specific Expression of a Splicing Mutation in the Gene Causes Familial Dysautonomia
2001
Signal-dependent degradation of I B is mediated by an inducible destruction box that can be transferred to NF- B, Bcl-3 or p53
1998
Transcription factor NF-κB is constitutively activated in acute lymphoblastic leukemia cells
2000
Lymphotoxin and lipopolysaccharide induce NF‐κB‐p52 generation by a co‐translational mechanism
2003
The IκB Kinase Complex and NF-κB Actas Master Regulators of Lipopolysaccharide-Induced Gene Expressionand Control Subordinate Activation ofAP-1
2004
Different mechanisms control signal-induced degradation and basal turnover of the NF-kappaB inhibitor IkappaB alpha in vivo.
1996
A pervasive role of ubiquitin conjugation in activation and termination of IκB kinase pathways
2005
Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells
2009
Nuclear Factor κB–dependent Gene Expression Profiling of Hodgkin's Disease Tumor Cells, Pathogenetic Significance, and Link to Constitutive Signal Transducer and Activator of Transcription 5a Activity
2002
Degradation of Bcl10 Induced by T-Cell Activation Negatively Regulates NF-κB Signaling
2004
Viral targeting of the interferon-β-inducing Traf family member-associated NF-κB activator (TANK)-binding kinase-1
2005
Shared Pathways of IκB Kinase-Induced SCFβTrCP-Mediated Ubiquitination and Degradation for the NF-κB Precursor p105 and IκBα
2001
B-Cell Receptor- and Phorbol Ester-Induced NF-κB and c-Jun N-Terminal Kinase Activation in B Cells Requires Novel Protein Kinase C's
2001
NF-κB Function in Growth Control: Regulation of Cyclin D1 Expression and G0/G1-to-S-Phase Transition
1999
Constitutive NF-κB maintains high expression of a characteristic gene network, including CD40, CD86, and a set of antiapoptotic genes in Hodgkin/Reed-Sternberg cells
2001
Critical role of PI3K signaling for NF-κB–dependent survival in a subset of activated B-cell–like diffuse large B-cell lymphoma cells
2010
Overexpression of I Kappa B Alpha Without Inhibition of NF-κB Activity and Mutations in the I Kappa B Alpha Gene in Reed-Sternberg Cells
1999
High-level nuclear NF-kappa B and Oct-2 is a common feature of cultured Hodgkin/Reed-Sternberg cells
1996
Overexpression of I Kappa B Alpha Without Inhibition of NF-κB Activity and Mutations in the I Kappa B Alpha Gene in Reed-Sternberg Cells
1999