Citation Impact
Citing Papers
Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs
2022 StandoutNobel
CRISPR–Cas9 Structures and Mechanisms
2017 StandoutNobel
Genome-Wide Analysis of Human Long Noncoding RNAs: A Provocative Review
2022
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
Spatiotemporal gene expression trajectories reveal developmental hierarchies of the human cortex
2017 Science
LncRNA GABPB1-AS1 and GABPB1 regulate oxidative stress during erastin-induced ferroptosis in HepG2 hepatocellular carcinoma cells
2019
Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
2018 StandoutNobel
MicroRNAs (miRNAs) and Long Non-Coding RNAs (lncRNAs) as New Tools for Cancer Therapy: First Steps from Bench to Bedside
2020
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Deep Patient: An Unsupervised Representation to Predict the Future of Patients from the Electronic Health Records
2016 Standout
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Ferroptosis: molecular mechanisms and health implications
2020 Standout
The Diversity of Long Noncoding RNAs and Their Generation
2017
O-GlcNAc and the Epigenetic Regulation of Gene Expression
2014
Structural perspective of cooperative transcription factor binding
2017
The Biogenesis, Functions, and Challenges of Circular RNAs
2018 Standout
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Genomic positional conservation identifies topological anchor point RNAs linked to developmental loci
2018
Hepatocellular carcinoma
2018 Standout
Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
2018
Sirtuin-7 Inhibits the Activity of Hypoxia-inducible Factors
2013 StandoutNobel
Am I ready for CRISPR? A user's guide to genetic screens
2017
Telomeres: history, health, and hallmarks of aging
2021
A CRISPR–dCas Toolbox for Genetic Engineering and Synthetic Biology
2018
Transforming Growth Factor-β Signaling in Immunity and Cancer
2019 Standout
ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice
2016
Applications of genome editing technology in the targeted therapy of human diseases: mechanisms, advances and prospects
2020 Standout
Cushing's syndrome
2015 Standout
Hallmarks of aging: An expanding universe
2023 Standout
Macrophages in immunoregulation and therapeutics
2023 Standout
Effective gene expression prediction from sequence by integrating long-range interactions
2021 StandoutNobel
Live Cell Imaging Reveals the Dynamics of Telomerase Recruitment to Telomeres
2016 Nobel
A CRISPR toolbox to study virus–host interactions
2017
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
The Human Transcription Factors
2018 Standout
Hepatocellular carcinoma
2021 Standout
The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force
2017
Regulatory Enhancer–Core-Promoter Communication via Transcription Factors and Cofactors
2016
Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments
2018
The ETS family of oncogenic transcription factors in solid tumours
2017
Hacking the Cancer Genome: Profiling Therapeutically Actionable Long Non-coding RNAs Using CRISPR-Cas9 Screening
2019
Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning
2015 Standout
Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution
2019
Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells
2016
Genome editing in cardiovascular diseases
2016
Non-coding driver mutations in human cancer
2021
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
Biological roles of glycans
2016 Standout
CRISPR interference-based specific and efficient gene inactivation in the brain
2018
High-Throughput Approaches to Pinpoint Function within the Noncoding Genome
2017
Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
2020 StandoutNobel
Genetic profiling of hepatocellular carcinoma using next-generation sequencing
2016
Deep learning and process understanding for data-driven Earth system science
2019 StandoutNature
Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors
2020 Standout
EMT: 2016
2016 Standout
Towards a complete map of the human long non-coding RNA transcriptome
2018
Combinatorial function of transcription factors and cofactors
2017
A guide to deep learning in healthcare
2018 Standout
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer
2017 Standout
The next generation of CRISPR–Cas technologies and applications
2019
Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations
2019
The biogenesis, biology and characterization of circular RNAs
2019 Standout
The role of telomeres and telomerase in cirrhosis and liver cancer
2019
A new era in functional genomics screens
2021
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood
2017 Nature
ROS and the DNA damage response in cancer
2018 Standout
The p53 Family Coordinates Wnt and Nodal Inputs in Mesendodermal Differentiation of Embryonic Stem Cells
2016
SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
2012 Nature
Artificial intelligence in radiology
2018 Standout
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Calcific aortic stenosis
2016
Single‐cell sequencing maps gene expression to mutational phylogenies in PDGF ‐ and EGF ‐driven gliomas
2016
Reversed graph embedding resolves complex single-cell trajectories
2017 Standout
Hepatocellular Carcinoma
2019 Standout
Evidence for orphan nuclear receptor TR4 in the etiology of Cushing disease
2013
Understanding development and stem cells using single cell-based analyses of gene expression
2017
CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine
2017
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
Learned protein embeddings for machine learning
2018 StandoutNobel
Physics-informed neural networks: A deep learning framework for solving forward and inverse problems involving nonlinear partial differential equations
2018 Standout
Geometric Deep Learning: Going beyond Euclidean data
2017 Standout
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
2022 Standout
Efficient Processing of Deep Neural Networks: A Tutorial and Survey
2017 Standout
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines
2020 Standout
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
2018 Standout
CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
2020 StandoutNobel
Endocardial Notch Signaling in Cardiac Development and Disease
2015
Works of Daniel He being referenced
The transcription factor GABP selectively binds and activates the mutant TERT promoter in cancer
2015 Science
CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells
2016 Science
Genome-wide binding of the orphan nuclear receptor TR4 suggests its general role in fundamental biological processes
2010
Single-cell analysis of long non-coding RNAs in the developing human neocortex
2016
Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency
2015
Acetylation of RNA Polymerase II Regulates Growth-Factor-Induced Gene Transcription in Mammalian Cells
2013
Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis
2016
Brg1 modulates enhancer activation in mesoderm lineage commitment
2015