Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets
2013
Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27–CD70 pathway
2013
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen
2006
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP 3 inflammasome assembly
2019
Aire-Deficient C57BL/6 Mice Mimicking the Common Human 13-Base Pair Deletion Mutation Present with Only a Mild Autoimmune Phenotype
2009
Arrestin 3 Mediates Endocytosis of CCR7 following Ligation of CCL19 but Not CCL21
2008
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation
2019
Histone H3 Lysine 27 demethylases Jmjd3 and Utx are required for T-cell differentiation
2015
Hallmarks of Cancer: The Next Generation
2011 Standout
Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis
2013
Caspase-1 initiates apoptosis in the absence of gasdermin D
2019
Cardiac myocyte miR-29 promotes pathological remodeling of the heart by activating Wnt signaling
2017
Priming of naive T cells inside tumors leads to eradication of established tumors
2004
CCR7 and its ligands: balancing immunity and tolerance
2008
Mass Cytometry: Single Cells, Many Features
2016
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Role of C-C chemokine receptor type 7 and its ligands during neuroinflammation
2012
MicroRNA-205 Maintains T Cell Development following Stress by Regulating Forkhead Box N1 and Selected Chemokines
2016
Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice
2014
Regulatory T Cells
2000 StandoutNobel
Roles for MicroRNAs in Conferring Robustness to Biological Processes
2012
3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis
2020
Neutrophils in a mouse model of autoantibody‐mediated arthritis: Critical producers of Fc receptor γ, the receptor for C5a, and lymphocyte function−associated antigen 1
2010
BH3-Mimetic Drugs: Blazing the Trail for New Cancer Medicines
2018
Apoptotic Caspases: Multiple or Mistaken Identities?
2018
A decade of AIRE
2007
Central tolerance: learning self-control in the thymus
2005
Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation
2010
TRAF2 Sets a Threshold for Extrinsic Apoptosis by Tagging Caspase-8 with a Ubiquitin Shutoff Timer
2012
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design
2017
The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
2005
Foxp3 Transcription Factor Is Proapoptotic and Lethal to Developing Regulatory T Cells unless Counterbalanced by Cytokine Survival Signals
2013
Comparing the effects of different cell death programs in tumor progression and immunotherapy
2018
Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells
2010 Standout
Estimating the proportion of microarray probes expressed in an RNA sample
2010
The Cellular Mechanism of Aire Control of T Cell Tolerance
2005
Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis
2016
Metazoan MicroRNAs
2018 Standout
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
2003 StandoutNatureNobel
Translational research in immunology: Japanese perspectives
2004
Caspase Functions in Cell Death and Disease
2013 Standout
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
2010
C1q and tumor necrosis factor superfamily: modularity and versatility
2004
Dynamic expression of transcription factors T-bet and GATA-3 by regulatory T cells maintains immunotolerance
2014
Peripheral regulatory T lymphocytes recirculating to the thymus suppress the development of their precursors
2015
Defective germinal center B-cell response and reduced arthritic pathology in microRNA-29a-deficient mice
2017
Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling
2007
Guidance of regulatory T cell development by Satb1-dependent super-enhancer establishment
2016 StandoutNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
2013 Standout
Fine tuning type I interferon responses
2013
Regulation of type I interferon responses
2013 Standout
Mitochondria as multifaceted regulators of cell death
2019 Standout
Metal-Organic Framework Nanoparticle-Based Biomineralization: A New Strategy toward Cancer Treatment
2019
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
2011
To be, or not to be
2013
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Regulation of death receptor signaling by the ubiquitin system
2009
Aire regulates negative selection of organ-specific T cells
2003
Mitochondria and cell death: outer membrane permeabilization and beyond
2010 Standout
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
2008 StandoutNature
Mitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation, and autoimmunity
2015
The microRNA-29 Family Dictates the Balance Between Homeostatic and Pathological Glucose Handling in Diabetes and Obesity
2015
I787 provides signals for c-Kit receptor internalization and functionality that control mast cell survival and development
2010 StandoutNobel
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
CD28 co-stimulation is dispensable for the steady state homeostasis of intestinal regulatory T cells
2018
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Characterization of the thymic IL-7 niche in vivo
2009
Molecular biology of Bax and Bak activation and action
2010
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Aire
2009
miR-29ab1 Deficiency Identifies a Negative Feedback Loop Controlling Th1 Bias That Is Dysregulated in Multiple Sclerosis
2012
Cytoprotective metal-organic frameworks for anaerobic bacteria
2018 StandoutNobel
REGULATION OF LYMPHOID DEVELOPMENT, DIFFERENTIATION, AND FUNCTION BY THE NOTCH PATHWAY
2005
Dependence of Self-Tolerance on TRAF6-Directed Development of Thymic Stroma
2005 Science
Ultraviolet B–Induced Maturation of CD11b-Type Langerin− Dendritic Cells Controls the Expansion of Foxp3+ Regulatory T Cells in the Skin
2017 StandoutNobel
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a
2015
mir-276a strengthens Drosophila circadian rhythms by regulating timeless expression
2016 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
CCR7 Directs the Migration of Thymocytes into the Thymic Medulla
2004
Ontogeny and Regulation of IL-7-Expressing Thymic Epithelial Cells
2005
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
PD-1 deficiency reveals various tissue-specific autoimmunity by H-2band dose-dependent requirement of H-2g7for diabetes in NOD mice
2008 StandoutNobel
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
Ionizing Radiation Selectively Reduces Skin Regulatory T Cells and Alters Immune Function
2014 StandoutNobel
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands
2009 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development
2011
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
How defects in central tolerance impinge on a deficiency in regulatory T cells
2005
Enhanced Pathogenicity of Diabetogenic T Cells Escaping a Non-MHC Gene-Controlled Near Death Experience
2004
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Daniel H.D. Gray being referenced
Gene Dosage–limiting Role of Aire in Thymic Expression, Clonal Deletion, and Organ-specific Autoimmunity
2004
The Lymphotoxin Pathway Regulates Aire-Independent Expression of Ectopic Genes and Chemokines in Thymic Stromal Cells
2008
Lymphotoxin Pathway and Aire Influences on Thymic Medullary Epithelial Cells Are Unconnected
2007
The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation
2018
Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
2018
Generalized Resistance to Thymic Deletion in the NOD Mouse
2004
Genetic Inversion in Mast Cell-Deficient Wsh Mice Interrupts Corin and Manifests as Hematopoietic and Cardiac Aberrancy
2008
Analysis of thymic stromal cell populations using flow cytometry
2002
Thymic generation and regeneration
2003
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor
2011
Homeostatic control of regulatory T cell diversity
2014
Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3+ regulatory T cells
2013
p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa
2013
Role for CCR7 Ligands in the Emigration of Newly Generated T Lymphocytes from the Neonatal Thymus
2002
The transcriptional landscape of αβ T cell differentiation
2013
Combined immune checkpoint blockade as a therapeutic strategy for BRCA1 -mutated breast cancer
2017
The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens
2012
Physiological restraint of Bak by Bcl-x L is essential for cell survival
2016
XIAP discriminates between type I and type II FAS-induced apoptosis
2009 Nature
A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice
2017
Danger-free autoimmune disease in Aire-deficient mice
2007
Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire
2007
T cell-dependent immune response in C1q deficient mice: Defective IFN-γ production by antigen-specific T cells
1998
Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease
2013
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
2006
Defects in the Bcl-2–Regulated Apoptotic Pathway Lead to Preferential Increase of CD25lowFoxp3+ Anergic CD4+ T Cells
2011
A Unique Thymic Fibroblast Population Revealed by the Monoclonal Antibody MTS-15
2007
Stromal Cells Provide the Matrix for Migration of Early Lymphoid Progenitors Through the Thymic Cortex
2002
CCR7 Signals Are Essential for Cortex–Medulla Migration of Developing Thymocytes
2004