Citation Impact
Citing Papers
Potent CRISPR-Cas9 inhibitors from Staphylococcus genomes
2020 StandoutNobel
Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling
2009 StandoutScience
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
DNA capture by a CRISPR-Cas9–guided adenine base editor
2020 StandoutScienceNobel
CRISPR/Cas9 in Genome Editing and Beyond
2016
High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding
2017 StandoutNobel
Small Nuclear Ribonucleoprotein Remodeling During Catalytic Activation of the Spliceosome
2002 Science
Automated de novo prediction of native-like RNA tertiary structures
2007 StandoutNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
The structure of the 80S ribosome from Trypanosoma cruzi reveals unique rRNA components
2005 StandoutNobel
CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity
2018 StandoutScienceNobel
Extension of the crRNA enhances Cpf1 gene editing in vitro and in vivo
2018
Improved gRNA secondary structures allow editing of target sites resistant to CRISPR-Cas9 cleavage
2022 StandoutNobel
CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells
2017
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Multiple functions for the invariant AGC triad of U6 snRNA
2004
The group II intron ribonucleoprotein precursor is a large, loosely packed structure
2010 StandoutNobel
CRISPR/Cas9 genome editing in human hematopoietic stem cells
2018
Genetic effects on gene expression across human tissues
2017 StandoutNature
Precise Gene Editing Preserves Hematopoietic Stem Cell Function following Transient p53-Mediated DNA Damage Response
2019
Ultra-stable organic fluorophores for single-molecule research
2013
CRISPR RNAs trigger innate immune responses in human cells
2018
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
Large-Scale Proteomic Analysis of the Human Spliceosome
2002
CRISPR/Cas9 β-globin gene targeting in human haematopoietic stem cells
2016 Nature
Comprehensive proteomic analysis of the human spliceosome
2002 Nature
Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3
2015 StandoutNobel
Functional spliceosomal A complexes can be assembled in vitro in the absence of a penta-snRNP
2006
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity
2016
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
2018 StandoutNobel
Is the spliceosome a ribonucleoprotein enzyme?
2008
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Spliceosomal snRNAs
2002
In vitro and ex vivo strategies for intracellular delivery
2016 Nature
Human DDX3 functions in translation and interacts with the translation initiation factor eIF3
2008
An ionizable lipid toolbox for RNA delivery
2021 StandoutNobel
Directed evolution of adenine base editors with increased activity and therapeutic application
2020
Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
2015 Standout
U2–U6 RNA folding reveals a group II intron-like domain and a four-helix junction
2004
Exploring functional relationships between components of the gene expression machinery
2005
Enhanced proofreading governs CRISPR–Cas9 targeting accuracy
2017 StandoutNatureNobel
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
2011 StandoutNatureNobel
Structure and Function of the Pre-mRNA Splicing Machine
2008
The EF-G-like GTPase Snu114p Regulates Spliceosome Dynamics Mediated by Brr2p, a DExD/H Box ATPase
2006
Arrested yeast splicing complexes indicate stepwise snRNP recruitment during in vivo spliceosome assembly
2006 StandoutNobel
The impact of rare variation on gene expression across tissues
2017 Nature
Expansion of the eukaryotic proteome by alternative splicing
2010 StandoutNature
Spliceosome disassembly catalyzed by Prp43 and its associated components Ntr1 and Ntr2
2005
Repositioning of the Reaction Intermediate within the Catalytic Center of the Spliceosome
2006
Cotranscriptional Spliceosome Assembly Occurs in a Stepwise Fashion and Requires the Cap Binding Complex
2005
A Genome-Wide Analysis Indicates that Yeast Pre-mRNA Splicing Is Predominantly Posttranscriptional
2006 StandoutNobel
Cotranscriptional Spliceosome Assembly Dynamics and the Role of U1 snRNA:5′ss Base Pairing in Yeast
2005 StandoutNobel
Three-Dimensional Structure of the Native Spliceosome by Cryo-Electron Microscopy
2004
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
A thermostable Cas9 with increased lifetime in human plasma
2017 StandoutNobel
Proximity of conserved U6 and U2 snRNA elements to the 5′ splice site region in activated spliceosomes
2006
A role for ubiquitin in the spliceosome assembly pathway
2008
Proteomic analysis identifies a new complex required for nuclear pre‐mRNA retention and splicing
2004
Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases
2016
Selective organ targeting (SORT) nanoparticles for tissue-specific mRNA delivery and CRISPR–Cas gene editing
2020
Lessons from Enzyme Kinetics Reveal Specificity Principles for RNA-Guided Nucleases in RNA Interference and CRISPR-Based Genome Editing
2017
Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cells
2006
“Nought May Endure but Mutability”: Spliceosome Dynamics and the Regulation of Splicing
2008
The Ded1/DDX3 subfamily of DEAD-box RNA helicases
2014
Prp8 protein: At the heart of the spliceosome
2005
CasX enzymes comprise a distinct family of RNA-guided genome editors
2019 StandoutNatureNobel
Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery
2019
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
2018
Pre-mRNA Splicing
2003
Early organization of pre-mRNA during spliceosome assembly
2002
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
Purification and electron microscopic visualization of functional human spliceosomes
2002
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Genomes in Focus: Development and Applications of CRISPR‐Cas9 Imaging Technologies
2017 StandoutNobel
The chemistry of Cas9 and its CRISPR colleagues
2017 StandoutNobel
Selection-free genome editing of the sickle mutation in human adult hematopoietic stem/progenitor cells
2016
Chemical and Biophysical Modulation of Cas9 for Tunable Genome Engineering
2016 StandoutNobel
The U1 snRNP Base Pairs with the 5′ Splice Site within a Penta-snRNP Complex
2003
The Molecular Mechanics of Eukaryotic Translation
2004
Mass spectrometry-based proteomics
2003 StandoutNature
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
On the importance of being co-transcriptional
2002
The epigenetic landscape of T cell exhaustion
2016 Science
A New Class of Medicines through DNA Editing
2019
Crystal structure of the β-finger domain of Prp8 reveals analogy to ribosomal proteins
2008
2015
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing
2018
Delivery technologies for genome editing
2017
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
2019
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6
2017
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Cas9 interrogates DNA in discrete steps modulated by mismatches and supercoiling
2020 StandoutNobel
Retroviral Splicing Suppressor Sequesters a 3′ Splice Site in a 50S Aberrant Splicing Complex
2005
Allosteric Cascade of Spliceosome Activation
2002
Engineering of temperature- and light-switchable Cas9 variants
2013 StandoutNobel
Universal intracellular biomolecule delivery with precise dosage control
2018
Nanometer resolution imaging and tracking of fluorescent molecules with minimal photon fluxes
2016 StandoutScienceNobel
Genome Editing: A New Approach to Human Therapeutics
2015
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
CRISPR-Cas guides the future of genetic engineering
2018 StandoutScienceNobel
Synthetic CRISPR RNA-Cas9–guided genome editing in human cells
2015
Cancer immunotherapy using checkpoint blockade
2018 StandoutScience
Mechanisms of Alternative Pre-Messenger RNA Splicing
2003 Standout
Protein Displacement by DExH/D "RNA Helicases" Without Duplex Unwinding
2004 Science
Effects of the U1C L13 mutation and temperature regulation of yeast commitment complex formation
2004 StandoutNobel
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
2004 StandoutNobel
Nontoxic nanopore electroporation for effective intracellular delivery of biological macromolecules
2019 StandoutNobel
Works of Daniel E. Ryan being referenced
New tertiary constraints between the RNA components of active yeast spliceosomes: A photo-crosslinking study
2004
Chemically modified guide RNAs enhance CRISPR-Cas genome editing in human primary cells
2015
Composition and Functional Characterization of the Yeast Spliceosomal Penta-snRNP
2002
Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34+ Hematopoietic Stem and Progenitor Cells
2018
Conformational dynamics of single pre-mRNA molecules during in vitro splicing
2010
Improving CRISPR–Cas specificity with chemical modifications in single-guide RNAs
2017
The conserved central domain of yeast U6 snRNA: Importance of U2-U6 helix Ia in spliceosome assembly
2002