Citation Impact
Citing Papers
Role of Sec61p in the ER-associated degradation of short-lived transmembrane proteins
2008 StandoutNobel
Single, context-specific glycans can target misfolded glycoproteins for ER-associated degradation
2005
Simultaneous induction of the four subunits of the TRAP complex by ER stress accelerates ER degradation
2007
Structural elements of Gα subunits that interact with Gβγ, receptors, and effectors
1993
From molecular to modular cell biology
1999 StandoutNatureNobel
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Signal Transduction During Pheromone Response in Yeast
1991
Constitutive mutants in the yeast pheromone response: Ordered function of the gene products
1989
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Size selection identifies new genes that regulate Saccharomyces cerevisiae cell proliferation.
1990
Saccharomyces cerevisiae mata mutant cells defective in pointed projection formation in response to α‐factor at high concentrations
1994 StandoutNobel
Pheromone-induced phosphorylation of a G protein β subunit in S. cerevisiae is associated with an adaptive response to mating pheromone
1991
FAR1 links the signal transduction pathway to the cell cycle machinery in yeast
1993
Hormonal stimulation of adenylyl cyclase through Gi-protein βγ subunits
1992 Nature
Sex, stress and integrity: the importance of MAP kinases in yeast
1994
Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation
1995 Standout
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
The GTPase superfamily: a conserved switch for diverse cell functions
1990 StandoutNature
Membrane recruitment of the kinase cascade scaffold protein Ste5 by the Gβγ complex underlies activation of the yeast pheromone response pathway
1998
Use of Modular Substrates Demonstrates Mechanistic Diversity and Reveals Differences in Chaperone Requirement of ERAD
2003
The DAF2-2 mutation, a dominant inhibitor of the STE4 step in the alpha-factor signaling pathway of Saccharomyces cerevisiae MAT alpha cells.
1990
Recombinant G-protein βγ-subunits activate the muscarinic-gated atrial potassium channel
1994 StandoutNatureNobel
A mammalian guanine-nucleotide-releasing protein enhances function of yeast secretory protein Sec4
1993 Nature
A Distinct Nuclear Import Pathway Used by Ribosomal Proteins
1997 StandoutNobel
The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tags
2005
Structural determinants for activation of the α-subunit of a heterotrimeric G protein
1994 Nature
A regulatory hierarchy for cell specialization in yeast
1989 Nature
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
1994 Nature
Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2
1990
Structures of active conformations of Gi alpha 1 and the mechanism of GTP hydrolysis
1994 StandoutScienceNobel
Enzymes Required for Yeast Prohormone Processing
1988
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
The structure of the G protein heterotrimer Giα1β1γ2
1995 Nobel
The importance of G-protein βλ subunits
1993 StandoutNobel
Mutations that suppress the thermosensitivity of green fluorescent protein
1996
The drosophila gastrulation gene concertina encodes a Gα-like protein
1991 StandoutNobel
Role of poly(ADP-ribose) formation in DNA repair
1992 StandoutNatureNobel
Yeast KEX2 gene encodes an endopeptidase homologous to subtilisin-like serine proteases
1988
COPII–cargo interactions direct protein sorting into ER-derived transport vesicles
1998 StandoutNatureNobel
Signal sorting and amplification through G protein-coupled receptors
1989
Phermone response in yeast
1990
MAP kinase pathways in yeast: For mating and more
1995
Yos9p Detects and Targets Misfolded Glycoproteins for ER-Associated Degradation
2005
ERAD: the long road to destruction
2005
Who carries what message?
1989 Nature
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Substitution of three amino acids switches receptor specificity of Gqα to that of Giα
1993 StandoutNatureNobel
Signal transduction by MAP kinase cascades in budding yeast
1998
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
2000 StandoutNatureNobel
Diversity among the beta subunits of heterotrimeric GTP-binding proteins: Characterization of a novel beta-subunit cDNA
1992
FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation
1990
New roles for G-protein (βγ-dimers in transmembrane signalling
1993 Nature
Oligosaccharide Modification in the Early Secretory Pathway Directs the Selection of a Misfolded Glycoprotein for Degradation by the Proteasome
1999
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
The role of Rab3A in neurotransmitter release
1994 StandoutNatureNobel
SGV1 encodes a CDC28/cdc2-related kinase required for a Gα subunit-mediated adaptive response to pheromone in S. cerevisiae
1991
Activation of the cloned muscarinic potassium channel by G protein βγ subunits
1994 StandoutNatureNobel
A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae
1989
Nonfilamentous C. albicans Mutants Are Avirulent
1997 Standout
Conjugation in Saccharomyces cerevisiae
1988 StandoutNobel
An integral membrane component of coatomer-coated transport vesicles defines a family of proteins involved in budding.
1995 StandoutNobel
Stoichiometry of G protein subunits affects the Saccharomyces cerevisiae mating pheromone signal transduction pathway.
1990
Kap104p: A Karyopherin Involved in the Nuclear Transport of Messenger RNA Binding Proteins
1996 StandoutScienceNobel
Nonstructural Protein 5A of Hepatitis C Virus Inhibits the Function of Karyopherin β3
2000
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
G protein beta gamma subunits. Simplified purification and properties of novel isoforms.
1994 StandoutNobel
G protein diversity is increased by associations with a variety of gamma subunits.
1990
Overproduction of the yeast STE12 protein leads to constitutive transcriptional induction.
1990
Recycling of proteins from the Golgi compartment to the ER in yeast.
1990
Candida albicans strains heterozygous and homozygous for mutations in mitogen-activated protein kinase signaling components have defects in hyphal development
1996
Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling.
1990
Newly Synthesized Hepatitis C Virus Replicon RNA Is Protected from Nuclease Activity by a Protease-Sensitive Factor(s)
2004
The yeast GAL11 protein binds to the transcription factor IIE through GAL11 regions essential for its in vivo function.
1996 StandoutNobel
Existence of Two γ Subunits of the G Proteins in Brain
1989
EDEM As an Acceptor of Terminally Misfolded Glycoproteins Released from Calnexin
2003 Science
The yeast STE12 protein binds to the DNA sequence mediating pheromone induction.
1989
Ras2 signals via the Cdc42/Ste20/mitogen-activated protein kinase module to induce filamentous growth in Saccharomyces cerevisiae.
1996
Role of EDEM in the Release of Misfolded Glycoproteins from the Calnexin Cycle
2003 Science
Karyopherin β2 mediates nuclear import of a mRNA binding protein
1997 StandoutNobel
FUS3 phosphorylates multiple components of the mating signal transduction cascade: evidence for STE12 and FAR1.
1993
Coat Proteins and Vesicle Budding
1996 StandoutScienceNobel
Characterization of the proteasome interaction with the Sec61 channel in the endoplasmic reticulum
2007
STE12, a protein involved in cell-type-specific transcription and signal transduction in yeast, is part of protein-DNA complexes.
1989
On the mechanism of G protein beta gamma subunit activation of the muscarinic K+ channel in guinea pig atrial cell membrane. Comparison with the ATP-sensitive K+ channel.
1992
The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase.
1993 StandoutNobel
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
GPA1Val-50 mutation in the mating-factor signaling pathway in Saccharomyces cerevisiae.
1989
Efficient Initiation of HCV RNA Replication in Cell Culture
2000 StandoutScienceNobel
Functional domains of the yeast STE12 protein, a pheromone-responsive transcriptional activator.
1993
FAR1 links the signal transduction pathway to the cell cycle machinery in yeast
1993
Yeast pheromone response pathway: characterization of a suppressor that restores mating to receptorless mutants.
1989
How N-linked oligosaccharides affect glycoprotein folding in the endoplasmic reticulum.
1994
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus)
1996 StandoutNobel
Constitutive mutants of the protein kinase STE11 activate the yeast pheromone response pathway in the absence of the G protein.
1992
Regulation of APP-Dependent Transcription Complexes by Mint/X11s: Differential Functions of Mint Isoforms
2002 StandoutNobel
Saccharomyces cerevisiae cells execute a default pathway to select a mate in the absence of pheromone gradients.
1995 StandoutNobel
Identification of 21 novel human protein kinases, including 3 members of a family related to the cell cycle regulator nimA of Aspergillus nidulans.
1993
Courtship in Saccharomyces cerevisiae: an Early Cell-Cell Interaction during Mating
1990 StandoutNobel
G proteins and βARK: a new twist for the coiled coil
1993
G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma
1992 StandoutNobel
Activation of cytosolic phosphoinositide phospholipase C by G-protein beta gamma subunits
1992
Elements of the Yeast Pheromone Response Pathway Required for Filamentous Growth of Diploids
1993 Science
Regulation of the yeast pheromone response pathway by G protein subunits.
1990
Neuronal expression of a newly identified Drosophila melanogaster G protein alpha 0 subunit.
1989
STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast.
1990
Pheromone-dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation.
1991
The carboxyl terminus of Scg1, the G alpha subunit involved in yeast mating, is implicated in interactions with the pheromone receptors.
1991
G PROTEIN βγ SUBUNITS
1997
Mutational Activation of the STE5 Gene Product Bypasses the Requirement for G Protein β and γ Subunits in the Yeast Pheromone Response Pathway
1994
The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
1993 StandoutNatureNobel
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor
1995 StandoutScienceNobel
The absence of Emp24p, a component of ER-derived COPII-coated vesicles, causes a defect in transport of selected proteins to the Golgi.
1995
Clathrin: A Role in the Intracellular Retention of a Golgi Membrane Protein
1989 StandoutScienceNobel
Yeast Pheromone Response Pathway: Characterization of a Suppressor That Restores Mating to Receptorless Mutants
1989
Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
2004
Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence.
1993
FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction.
1991
Isolation and functional expression of a mammalian prohormone processing enzyme, murine prohormone convertase 1.
1991 StandoutNobel
Carboxyl methylation and farnesylation of transducin gamma-subunit synergistically enhance its coupling with metarhodopsin II.
1991
Prepro-alpha-factor has a cleavable signal sequence.
1988 StandoutNobel
Control of Yeast Mating Signal Transduction by a Mammalian β 2 -adrenergic Receptor and G s α Subunit
1990 StandoutScienceNobel
Isolation from Candida albicans of a functional homolog of the Saccharomyces cerevisiae KRE1 gene, which is involved in cell wall beta-glucan synthesis
1991
Cloning and characterization of human karyopherin β3
1997 StandoutNobel
Nuclear Import of the TATA-binding Protein: Mediation by the Karyopherin Kap114p and a Possible Mechanism for Intranuclear Targeting
1999 StandoutNobel
Quality control in the endoplasmic reticulum
2003 Standout
ERS-24, a Mammalian v-SNARE Implicated in Vesicle Traffic between the ER and the Golgi
1997 StandoutNobel
Order of action of components in the yeast pheromone response pathway revealed with a dominant allele of the STE11 kinase and the multiple phosphorylation of the STE7 kinase.
1992 StandoutNobel
Bimodal Interaction of Coatomer with the p24 Family of Putative Cargo Receptors
1996 Science
Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway.
1994
Mode of enzyme-bound poly(ADP-ribose) synthesis and histone modification by reconstituted poly(ADP-ribose) polymerase-DNA-cellulose complex.
1981
NMR structure of the calreticulin P-domain
2001 StandoutNobel
Protein Translocation Across Biological Membranes
2005 StandoutScienceNobel
Overexpression of the STE4 gene leads to mating response in haploid Saccharomyces cerevisiae.
1990
Modulation of Serotonin-Controlled Behaviors by G o in Caenorhabditis elegans
1995 Science
Structure and mechanism of the G protein-coupled receptor kinases.
1993 StandoutNobel
Works of Daniel Dignard being referenced
Cloning of Saccharomyces cerevisiae STE5 as a suppressor of a Ste20 protein kinase mutant: structural and functional similarity of Ste5 to Farl
1993
The Yeast KEX-2-Processing Endoprotease Is Active in the Golgi Apparatus of Transfected NIH 3T3 Fibroblasts
1990
The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein
1989
Constitutive activation of the Saccharomyces cerevislae mating response pathway by a MAP kinase kinase from Candida albicans
1995
Function of the STE4 and STE18 Genes in Mating Pheromone Signal Transduction in Saccharomyces cerevisiae
1988
SSR alpha and associated calnexin are major calcium binding proteins of the endoplasmic reticulum membrane.
1991
The protein kinase homologue Ste20p is required to link the yeast pheromone response G-protein beta gamma subunits to downstream signalling components.
1992
Dominant negative selection of heterologous genes: isolation of Candida albicans genes that interfere with Saccharomyces cerevisiae mating factor-induced cell cycle arrest.
1992
Interactions among the Subunits of the G Protein Involved in Saccharomyces cerevisiae Mating†
1993
Screening and identification of a gene, PSE-1, that affects protein secretion in Saccharomyces cerevisiae
1992
A family of yeast expression vectors containing the phage f1 intergenic region1
1987
Yeast KEX1 gene encodes a putative protease with a carboxypeptidase B-like function involved in killer toxin and α-factor precursor processing
1987
Genetic Identification of Residues Involved in Association of α and β G-Protein Subunits†
1994
Signal transduction through homologs of the Ste20p and Ste7p protein kinases can trigger hyphal formation in the pathogenic fungus Candida albicans
1996
Interactions among the subunits of the G protein involved in Saccharomyces cerevisiae mating.
1993
Dominant-negative mutants of a yeast G-protein beta subunit identify two functional regions involved in pheromone signalling.
1992
Htm1p, a mannosidase‐like protein, is involved in glycoprotein degradation in yeast
2001