Citation Impact
Citing Papers
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of β-catenin
2008
Cooexpression of FTDP-17 tau and GSK-3β in transgenic mice induce tau polymerization and neurodegeneration
2005
Synapses and Alzheimer's Disease
2012 StandoutNobel
PS1 activates PI3K thus inhibiting GSK‐3 activity and tau overphosphorylation: effects of FAD mutations
2004
Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice
2000
Cancer chemoprevention with dietary phytochemicals
2003 Standout
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease
2001
The multifaceted roles of glycogen synthase kinase 3β in cellular signaling
2001 Standout
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
2007 Standout
The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
2008 Standout
β-Amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment
2000
Tau protein pathology in neurodegenerative diseases
1998
The role of autophagy in neurodegenerative disease
2013 Standout
Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils
2003
Cortical Hubs Revealed by Intrinsic Functional Connectivity: Mapping, Assessment of Stability, and Relation to Alzheimer's Disease
2009 Standout
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
Control of β-Catenin Phosphorylation/Degradation by a Dual-Kinase Mechanism
2002 Standout
Alzheimer's disease
2011 Standout
WNT and β-catenin signalling: diseases and therapies
2004 Standout
Transient Increases in Intracellular Calcium Result in Prolonged Site-selective Increases in Tau Phosphorylation through a Glycogen Synthase Kinase 3β-dependent Pathway
1999
Glycogen synthase kinase-3β, β-catenin, and tau in postmortem bipolar brain
1999
Transcriptional regulation by calcium, calcineurin, and NFAT
2003 Standout
GSK3 inhibitors show benefits in an Alzheimer's disease (AD) model of neurodegeneration but adverse effects in control animals
2008
Empathy Decline and Its Reasons: A Systematic Review of Studies With Medical Students and Residents
2011
Conditional Forebrain Inactivation of Nicastrin Causes Progressive Memory Impairment and Age-Related Neurodegeneration
2009 StandoutNobel
Structural Insights and Biological Effects of Glycogen Synthase Kinase 3-specific Inhibitor AR-A014418
2003
Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model
2007 Standout
Tau in physiology and pathology
2015 Standout
Efficacy of small‐molecule glycogen synthase kinase‐3 inhibitors in the postnatal rat model of tau hyperphosphorylation
2007
Roles of Wnt proteins in neural development and maintenance
2000 StandoutNobel
Untangling tau hyperphosphorylation in drug design for neurodegenerative diseases
2007
Insulin Transiently Increases Tau Phosphorylation
1999
Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein
1999
Linking Aβ and Tau in Late-Onset Alzheimer's Disease: A Dual Pathway Hypothesis
2008
Lithium inhibits amyloid secretion in COS7 cells transfected with amyloid precursor protein C100
2002
Wnt/β-Catenin Signaling and Disease
2012 Standout
Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
2009 Standout
The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase
2005 StandoutNobel
Neurovascular regulation in the normal brain and in Alzheimer's disease
2004 Standout
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
2001
Molecular mechanisms of neurodegeneration in Alzheimer's disease
2010
A β-arrestin 2 Signaling Complex Mediates Lithium Action on Behavior
2008 StandoutNobel
Glycogen Synthase Kinase-3β Activity Is Critical for Neuronal Death Caused by Inhibiting Phosphatidylinositol 3-Kinase or Akt but Not for Death Caused by Nerve Growth Factor Withdrawal
2000
GSK3 inhibitors: development and therapeutic potential
2004
Cdk5 is involved in NFT-like tauopathy induced by transient cerebral ischemia in female rats
2006
The role of tau in Alzheimer's disease
2002
Does Lithium Prevent Alzheimerʼs Disease?
2012
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
2013 Standout
Phosphorylation of microtubule-associated protein 2 (MAP2) and its relevance for the regulation of the neuronal cytoskeleton function
2000
Listening to silence and understanding nonsense: exonic mutations that affect splicing
2002 Standout
Alzheimer's disease
2006 Standout
Alzheimer's disease
2016 Standout
Glycogen synthase kinase 3β inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism
2017 StandoutNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Lithium neuroprotection: molecular mechanisms and clinical implications
2004
The interrelationship between selective tau phosphorylation and microtubule association
1998
Pharmacophore-based screening and drug repurposing exemplified on glycogen synthase kinase-3 inhibitors
2017
Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations
1999
Alzheimer's Disease
2010 Standout
Filamentous nerve cell inclusions in neurodegenerative diseases
1998
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Protein Kinase A Negatively Modulates the Nuclear Accumulation of NF-ATc1 by Priming for Subsequent Phosphorylation by Glycogen Synthase Kinase-3
2002
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation
1999
The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions
2003 Standout
The Pathobiology of Vascular Dementia
2013 Standout
The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
2012 Standout
Tau pathology in Alzheimer disease and other tauopathies
2004
HIV‐1 Tat‐Mediated Activation of Glycogen Synthase Kinase‐3β Contributes to Tat‐Mediated Neurotoxicity
1999
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
The molecular pathology of Alzheimer's disease
1991 Standout
Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription
2000
Lithium-related genetics of bipolar disorder
2001
Mutant Presenilin-1 Induces Apoptosis and Downregulates Akt/PKB
1999
Neurodegenerative Tauopathies
2001 Standout
Regulation of Glycogen Synthase Kinase 3β and Downstream Wnt Signaling by Axin
1999
Glycogen synthase kinase 3β phosphorylation of microtubule-associated protein 1B regulates the stability of microtubules in growth cones
1999
A Century of Alzheimer's Disease
2006 StandoutScience
Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degenerationin vivo
2005
Dishevelled-1 Regulates Microtubule Stability
2000
Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3β
2003
Wnt signaling and cancer
2000 Standout
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Glycogen Synthase Kinase-3 Mediates Endothelial Cell Activation by Tumor Necrosis Factor-α
2005
Judging a Protein by More Than Its Name: GSK-3
2001
From genetics to pathology: tau and a–synuclein assemblies in neurodegenerative diseases
2001
Lithium, a Common Drug for Bipolar Disorder Treatment, Regulates Amyloid-β Precursor Protein Processing
2004
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Intraneuronal amyloid‐β1‐42 production triggered by sustained increase of cytosolic calcium concentration induces neuronal death
2004
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Inhibition of GSK-3β leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-7a or lithium
1998
Phosphorylated tau can promote tubulin assembly
1999
THE WNT SIGNALING PATHWAY IN DEVELOPMENT AND DISEASE
2004 Standout
Molecular Targets of Lithium Action
2001
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
The selectivity of protein kinase inhibitors: a further update
2007 Standout
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
PubChem in 2021: new data content and improved web interfaces
2020 Standout
Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons
1999
Racial bias in pain assessment and treatment recommendations, and false beliefs about biological differences between blacks and whites
2016 Standout
Lithium Treatment Arrests the Development of Neurofibrillary Tangles in Mutant Tau Transgenic Mice with Advanced Neurofibrillary Pathology
2010
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Wnt signaling function in Alzheimer’s disease
2000
Works of Daniel Chen being referenced
Lithium Reduces Tau Phosphorylation by Inhibition of Glycogen Synthase Kinase-3
1997
Comparing a Self-Administered Measure of Empathy with Observed Behavior Among Medical Students
2009
A Cross-sectional Measurement of Medical Student Empathy
2007