Citation Impact
Citing Papers
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
2008 Standout
A selective PIKfyve inhibitor blocks PtdIns(3,5)P 2 production and disrupts endomembrane transport and retroviral budding
2008
ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
2009 StandoutScience
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
2016
Hallmarks of Cancer: The Next Generation
2011 Standout
FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
2010 StandoutNobel
Down-Regulation of Na+/K+ATPase Activity by Human Parvovirus B19 Capsid Protein VP1
2013 Standout
Inositol Pyrophosphates Inhibit Akt Signaling, Thereby Regulating Insulin Sensitivity and Weight Gain
2010
Chapter 2 PI3K/PTEN Signaling in Angiogenesis and Tumorigenesis
2009
mTOR Signaling in Growth Control and Disease
2012 Standout
Can we safely target the WNT pathway?
2014
mTOR·RICTOR Is the Ser473 Kinase for Akt/Protein Kinase B in 3T3-L1 Adipocytes
2005
The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism
2006 Standout
AMPK: guardian of metabolism and mitochondrial homeostasis
2017 Standout
Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
2012 Standout
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy
2011
ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression
2013
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
2009 Standout
Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer
2016
Mammalian phosphoinositide kinases and phosphatases
2009 StandoutNobel
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
STRING v10: protein–protein interaction networks, integrated over the tree of life
2014 Standout
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Hallmarks of aging: An expanding universe
2023 Standout
The Warburg Effect Dictates the Mechanism of Butyrate-Mediated Histone Acetylation and Cell Proliferation
2012
Akt-dependent transformation: there is more to growth than just surviving
2005
Regulation of PIKfyve phosphorylation by insulin and osmotic stress
2010
Cancer stem cells revisited
2017 Standout
Acetyl Coenzyme A: A Central Metabolite and Second Messenger
2015
Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
2005
The Role of Phosphoinositide 3-Kinase C2α in Insulin Signaling
2007
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1
2006
Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis
2008
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
ATP citrate lyase is an important component of cell growth and transformation
2005
Regulation of cancer cell metabolism
2011 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner
2003
mTOR: from growth signal integration to cancer, diabetes and ageing
2010 Standout
The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid β-oxidation
2005
Autophagy in Human Health and Disease
2013 Standout
The GLUT4 Glucose Transporter
2007
Beginnings of a signal-transduction pathway for bioenergetic control of cell survival
2004
From Dietary Fiber to Host Physiology: Short-Chain Fatty Acids as Key Bacterial Metabolites
2016 Standout
A novel PtdIns3P and PtdIns(3,5)P2 phosphatase with an inactivating variant in centronuclear myopathy
2006
ArPIKfyve–PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes
2007
SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth
2008
The Emerging Hallmarks of Cancer Metabolism
2016 Standout
A Role for 14-3-3 in Insulin-stimulated GLUT4 Translocation through Its Interaction with the RabGAP AS160
2006
PI3K/Akt: getting it right matters
2008
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Regulation of the Glutamate Transporter EAAT4 by PIKfyve
2010
Akt signalling in health and disease
2011 Standout
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Identification of p122RhoGAP (Deleted in Liver Cancer-1) Serine 322 as a Substrate for Protein Kinase B and Ribosomal S6 Kinase in Insulin-stimulated Cells
2005
ATP citrate lyase inhibition can suppress tumor cell growth
2005
Linking pathways in the developing and aging brain with neurodegeneration
2014
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
The PI3K Pathway in Human Disease
2017 Standout
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Cell regulation: determined to signal discrete cooperation
2009
Rictor/TORC2 regulates fat metabolism, feeding, growth, and life span in Caenorhabditis elegans
2009 StandoutNobel
Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities
2017 Standout
Isoform-specific requirement for Akt1 in the developmental regulation of cellular metabolism during lactation
2006
PIKfyve: Partners, significance, debates and paradoxes
2008
Mitochondrial Dysfunction in Genetic Animal Models of Parkinson's Disease
2011
Beyond aerobic glycolysis: Transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis
2007 Standout
PTEN
2014
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
ATP Citrate Lyase: Activation and Therapeutic Implications in Non–Small Cell Lung Cancer
2008
DNA methylation signatures in Blood DNA of Hutchinson–Gilford Progeria syndrome
2022
Physiological roles of PKB/Akt isoforms in development and disease
2007
Phosphatidylinositol 3-Phosphate [PtdIns(3)P] Is Generated at thePlasma Membrane by an Inositol Polyphosphate 5-Phosphatase: Endogenous PtdIns(3)P Can Promote GLUT4 Translocation to the Plasma Membrane
2006
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
A circadian gene expression atlas in mammals: Implications for biology and medicine
2014 Standout
Combining chemical genetics and proteomics to identify protein kinase substrates
2005
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Spermidine in health and disease
2018 StandoutScience
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation
2017 StandoutNobel
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2007 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Inflammation and metabolism in tissue repair and regeneration
2017 StandoutScience
Cytokine Stimulation Promotes Glucose Uptake via Phosphatidylinositol-3 Kinase/Akt Regulation of Glut1 Activity and Trafficking
2007
Turning Signals On and Off: GLUT4 Traffic in the Insulin-Signaling Highway
2005
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Works of Daniel C. Berwick being referenced
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles
2004
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus
2019
The Identification of ATP-citrate Lyase as a Protein Kinase B (Akt) Substrate in Primary Adipocytes
2002
LRRK2 signaling pathways: the key to unlocking neurodegeneration?
2011
Identifying protein kinase substrates: hunting for the organ-grinder's monkeys
2004
The importance of Wnt signalling for neurodegeneration in Parkinson's disease
2012
Role of protein kinase B in insulin-regulated glucose uptake
2005