Citation Impact
Citing Papers
An optimized transgenesis system for Drosophila using germ-line-specific φC31 integrases
2007 Standout
Local regulation of gene expression by lncRNA promoters, transcription and splicing
2016 Nature
Linking class-switch recombination with somatic hypermutation
2001 StandoutNobel
Modulating gene expression using DNA vaccines with different 3′-UTRs influences antibody titer, seroconversion and cytokine profiles
2003
Fgf8 is required for outgrowth and patterning of the limbs
2000 StandoutNobel
The β Sliding Clamp Binds to Multiple Sites within MutL and MutS
2006 StandoutNobel
Alternative isoform regulation in human tissue transcriptomes
2008 StandoutNature
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
2016
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Early Formation of mRNP
2003 StandoutNobel
Interruption of coding sequences by heterologous introns can enhance the functional expression of recombinant genes
2001
A Block to mRNA Nuclear Export in S. cerevisiae Leads to Hyperadenylation of Transcripts that Accumulate at the Site of Transcription
2001 StandoutNobel
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
2016 StandoutNobel
In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants
2006 StandoutNobel
Sensitive analysis of recombination activity using integrated cell surface reporter substrates
1999
Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells
2005
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair
2003
An extrachromosomal switch recombination substrate reveals kinetics and substrate requirements of switch recombination in primary murine B cells
1999
Targeted transgene insertion into human chromosomes by adeno-associated virus vectors
2002
Evolution of a designed protein assembly encapsulating its own RNA genome
2017 StandoutNatureNobel
Gene targeting in mice: functional analysis of the mammalian genome for the twenty-first century
2005 StandoutNobel
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
2004 StandoutNobel
Cloning and chromosome mapping of the human Mel-18 gene which encodes a DNA-binding protein with a new ‘RING-finger’ motif
1993
RNA travel: Tracks from DNA to cytoplasm
1993 StandoutNobel
EM Visualization of Transcription by RNA Polymerase II
1999
Comprehensive Analysis of mRNA Methylation Reveals Enrichment in 3′ UTRs and near Stop Codons
2012 Standout
Enhanced efficiency through nuclear localization signal fusion on phage phiC31-integrase: activity comparison with Cre and FLPe recombinase in mammalian cells
2002
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
2011 StandoutNature
Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells
2003 Standout
Genome engineering using the CRISPR-Cas9 system
2013 Standout
A Genome-Wide Analysis Indicates that Yeast Pre-mRNA Splicing Is Predominantly Posttranscriptional
2006 StandoutNobel
Sense transcription through the S region is essential for immunoglobulin class switch recombination
2011
Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription
2006
Cotranscriptional Spliceosome Assembly Dynamics and the Role of U1 snRNA:5′ss Base Pairing in Yeast
2005 StandoutNobel
The RING finger/B-Box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans
1999 StandoutNobel
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9
2014
Intergenic transcription and transinduction of the human β-globin locus
1997
Multiple links between transcription and splicing
2004
Nascent-seq indicates widespread cotranscriptional pre-mRNA splicing in Drosophila
2011 StandoutNobel
Widespread transcription at neuronal activity-regulated enhancers
2010 StandoutNature
CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
2016 Standout
From head to toes: the multiple facets of Sox proteins
1999 Standout
Pausing of reverse transcriptase on retroviral RNA templates is influenced by secondary structures both 5' and 3' of the catalytic site
1998
Molecular Architecture of the Human Pre-mRNA 3′ Processing Complex
2009 StandoutNobel
Long Noncoding RNAs: Cellular Address Codes in Development and Disease
2013 Standout
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Long non-coding RNAs: insights into functions
2009 Standout
Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination
2011
Poly(A) signals
1991
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Biochemical analysis of TREX complex recruitment to intronless and intron‐containing yeast genes
2004 StandoutNobel
Molecular cloning and bacterial expression of cDNA for rat calpain II 80 kDa subunit
1993
Messenger RNAs that are not synthesized by RNA polymerase II can be 3′ end cleaved and polyadenylated
2000
Optimizing Promoters for Recombinant Adeno-Associated Virus-Mediated Gene Expression in the Peripheral and Central Nervous System Using Self-Complementary Vectors
2011
SH2 and SH3 Domains: Elements that Control Interactions of Cytoplasmic Signaling Proteins
1991 StandoutScience
Human La Protein: a Stabilizer of Histone mRNA
1997
Expression of Sry, the mouse sex determining gene
1995
Specific Expression of a Tyrosine Kinase Gene, blk , in B Lymphoid Cells
1990 Science
Transcription, β–like DNA polymerases and hypermutation
2001
Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?
1991
Normal limb development in conditional mutants of Fgf4
2000 StandoutNobel
Point mutations upstream of the yeast ADH2 poly(A) site significantly reduce the efficiency of 3'-end formation.
1991
Molecular Mechanism of Class Switch Recombination: Linkage with Somatic Hypermutation
2002 StandoutNobel
EctodermalWnt3/β-cateninsignaling is required for the establishment and maintenance of the apical ectodermal ridge
2003 StandoutNobel
Multiple roles ofHoxa11andHoxd11in the formation of the mammalian forelimb zeugopod
2003 StandoutNobel
Formation of mRNA 3′ Ends in Eukaryotes: Mechanism, Regulation, and Interrelationships with Other Steps in mRNA Synthesis
1999
Dawdling polymerases allow introns time to splice
2003
The Calpain System
2003 Standout
AnFgf8mouse mutant phenocopies human 22q11 deletion syndrome
2002 StandoutNobel
U1 snRNP can influence 3'-splice site selection as well as 5'-splice site selection.
1991 StandoutNobel
Polypyrimidine Tract Binding Protein Modulates Efficiency of Polyadenylation
2004
Efficient modification of CCR5 in primary human hematopoietic cells using a megaTAL nuclease and AAV donor template
2015
Ribosome Components Are Associated with Sites of Transcription
2002 StandoutNobel
Nuclear Import and the Evolution of a Multifunctional RNA-binding Protein
1998 StandoutNobel
MAZ-dependent termination between closely spaced human complement genes.
1994
In vitro polyadenylation is stimulated by the presence of an upstream intron.
1990
DNA Double-Strand Breaks
2002 StandoutNobel
Point Mutations Upstream of the Yeast ADH2 Poly(A) Site Significantly Reduce the Efficiency of 3′-End Formation
1991
Splicing precedes polyadenylation during Drosophila E74A transcription.
1990
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Splicing Precedes Polyadenylation during Drosophila E74A Transcription
1990
Template Boundary in a Yeast Telomerase Specified by RNA Structure
2000 StandoutScienceNobel
Defects in mRNA 3'-end formation, transcription initiation, and mRNA transport associated with the yeast mutation prp20: possible coupling of mRNA processing and chromatin structure.
1992 StandoutNobel
Evolutionary Comparison of the Mechanism of DNA Cleavage with Respect to Immune Diversity and Genomic Instability
2012 StandoutNobel
Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved.
1995
RNA Polymerase II Carboxy-Terminal Domain Phosphorylation Is Required for Cotranscriptional Pre-mRNA Splicing and 3′-End Formation
2004
Works of Daniel Briggs being referenced
Direct demonstration of termination signals for RNA polymerase II from the sea urchin H2A histone gene
1989
A pause site for RNA polymerase II is associated with termination of transcription.
1991
Definition of an efficient synthetic poly(A) site.
1989