Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Estrogenic chemicals in plastic and oral contraceptives disrupt development of the fetal mouse prostate and urethra
2005
Pathological α-Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
2012 StandoutScience
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Gene Expression Preferentially Regulated by Tamoxifen in Breast Cancer Cells and Correlations with Clinical Outcome
2006
Hedgehog Signaling Is a Novel Therapeutic Target in Tamoxifen-Resistant Breast Cancer Aberrantly Activated by PI3K/AKT Pathway
2012
A Novel Somatic Mouse Model to Survey Tumorigenic Potential Applied to the Hedgehog Pathway
2006
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
2004
Estrogen Dendrimer Conjugates that Preferentially Activate Extranuclear, Nongenomic Versus Genomic Pathways of Estrogen Action
2005
1 Developmental roles and clinical significance of Hedgehog signaling
2003
Basal cell carcinomas: attack of the hedgehog
2008 Standout
Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma
2012 Standout
BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling
2005
Pathological Changes in Dopaminergic Nerve Cells of the Substantia Nigra and Olfactory Bulb in Mice Transgenic for Truncated Human α-Synuclein(1–120): Implications for Lewy Body Disorders
2006
Stromal factors involved in prostate carcinoma metastasis to bone
2003
Hedgehog: functions and mechanisms
2008 Standout
Selective Evolution of Stromal Mesenchyme with p53 Loss in Response to Epithelial Tumorigenesis
2005
Gli2 Is Targeted for Ubiquitination and Degradation by β-TrCP Ubiquitin Ligase
2006
The mechanisms of Hedgehog signalling and its roles in development and disease
2013 Standout
Targeting hypoxia in cancer therapy
2011 Standout
Therapeutic potential of resveratrol: the in vivo evidence
2006 Standout
Estrogen Receptors: How Do They Signal and What Are Their Targets
2007 Standout
Notch signaling is required for normal prostatic epithelial cell proliferation and differentiation
2005
Estrogen receptors and human disease
2006 Standout
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
2003 StandoutNature
Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research
2014 Standout
Cancer to bone: a fatal attraction
2011 Standout
Intravesicular Localization and Exocytosis of α-Synuclein and its Aggregates
2005
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
Estrogenic Regulation of Signaling Pathways and Homeobox Genes During Rat Prostate Development
2004
Cancer Metastasis: Building a Framework
2006 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development
2004
FGF-10 plays an essential role in the growth of the fetal prostate
2003
Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII
2011
Arrestin Development: Emerging Roles for β-arrestins in Developmental Signaling Pathways
2009 StandoutNobel
Environmental neurotoxic challenge of conditional alpha-synuclein transgenic mice predicts a dopaminergic olfactory-striatal interplay in early PD
2014
N-myc Downstream-regulated Gene 2, a Novel Estrogen-targeted Gene, Is Involved in the Regulation of Na+/K+-ATPase
2011
Development of α-synuclein immunoreactive astrocytes in the forebrain parallels stages of intraneuronal pathology in sporadic Parkinson’s disease
2007
Hormonal, cellular, and molecular control of prostatic development
2003
A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
2011 Standout
Fibroblast growth factor signalling: from development to cancer
2010 Standout
What pharmacologists can learn from recent advances in estrogen signalling
2003
Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis
2004
Gene Expression Profiling Leads to Identification of GLI1-binding Elements in Target Genes and a Role for Multiple Downstream Pathways in GLI1-induced Cell Transformation
2002
Inhibition of the Hedgehog Pathway in Advanced Basal-Cell Carcinoma
2009 Standout
Unraveling the therapeutic potential of the Hedgehog pathway in cancer
2013 Standout
Molecular genetics of prostate cancer
2000
Sex differences in autoimmune diseases
2011
Endocrine Regulation of Energy Metabolism by the Skeleton
2007 Standout
Gli and hedgehog in cancer: tumours, embryos and stem cells
2002
A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
2008 Standout
A rapid simple approach to quantify chromosome conformation capture
2009
Hedgehog signaling in animal development: paradigms and principles
2001 Standout
Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer
2010
Acute responses to phytoestrogens in small arteries from men with coronary heart disease
2005
Fibroblast growth factor receptor signaling through MEK–ERK is required for prostate bud induction
2007
In vivo effects of a GPR30 antagonist
2009
The dorsal motor nucleus of the vagus is not an obligatory trigger site of Parkinson's disease: a critical analysis of α‐synuclein staging
2007
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
2005 StandoutNature
Hedgehog beyond medulloblastoma and basal cell carcinoma
2010
Hedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active Site
2010
Non-motor features of Parkinson disease
2017 Standout
Cytotoxic effects induced by a combination of cyclopamine and gefitinib, the selective hedgehog and epidermal growth factor receptor signaling inhibitors, in prostate cancer cells
2005
Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity
2015 StandoutNature
Systematic Mutagenesis of α-Synuclein Reveals Distinct Sequence Requirements for Physiological and Pathological Activities
2012 StandoutNobel
Sex differences in immune responses
2016 Standout
Hedgehog signalling in prostate regeneration, neoplasia and metastasis
2004 Nature
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
2011 Nature
The canonical Notch/RBP-J signaling pathway controls the balance of cell lineages in mammary epithelium during pregnancy
2006 StandoutNobel
Identification of Ligands with Bicyclic Scaffolds Provides Insights into Mechanisms of Estrogen Receptor Subtype Selectivity
2006
On the range of Hedgehog signaling
2000
Evidence for an Expansion-Based Temporal Shh Gradient in Specifying Vertebrate Digit Identities
2004 Standout
Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened
2002 Standout
The role of Fgf10 signaling in branching morphogenesis and gene expression of the rat prostate gland: lobe-specific suppression by neonatal estrogens
2004
Mechanisms of implantation: strategies for successful pregnancy
2012 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Tumour stem cells and drug resistance
2005 Standout
β-Arrestin–Mediated Localization of Smoothened to the Primary Cilium
2008 StandoutScienceNobel
Molecular analysis of coordinated bladder and urogenital organ formation by Hedgehog signaling
2007
Endocrine-Disrupting Chemicals: An Endocrine Society Scientific Statement
2009 Standout
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Estrogen Receptor-β: Recent Lessons from in Vivo Studies
2006
Patched1 Regulates Hedgehog Signaling at the Primary Cilium
2007 StandoutScience
Stromal Progesterone Receptors Mediate Induction of Indian Hedgehog (IHH) in Uterine Epithelium and Its Downstream Targets in Uterine Stroma
2009
Small molecule modulation of Smoothened activity
2002 Standout
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Smoothened Signal Transduction Is Promoted by G Protein-Coupled Receptor Kinase 2
2006 StandoutNobel
Phosphoinositide 3-kinase and Akt are essential for Sonic Hedgehog signaling
2006
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Selective Estrogen Receptor Modulators Differentially Regulate Alzheimer-Like Changes in Female 3xTg-AD Mice
2008
Hoxb13is required for normal differentiation and secretory function of the ventral prostate
2003 StandoutNobel
Estrogens protect pancreatic β-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice
2006
Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty
2004
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
2001 Standout
Regulatory Principles of Developmental Signaling
2002 StandoutNobel
The Hedgehog Signaling Pathway in Cancer
2006
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Role of epithelial cell fibroblast growth factor receptor substrate 2α in prostate development, regeneration and tumorigenesis
2008
Indazole Estrogens: Highly Selective Ligands for the Estrogen Receptor β
2005
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Daniel Barnett being referenced
Epitope mapping and specificity of the anti-α-synuclein monoclonal antibody Syn-1 in mouse brain and cultured cell lines
2003
Mesenchymal Factor Bone Morphogenetic Protein 4 Restricts Ductal Budding and Branching Morphogenesis in the Developing Prostate
2001
Activities of estrogen receptor alpha- and beta-selective ligands at diverse estrogen responsive gene sites mediating transactivation or transrepression
2003
Sonic hedgehog signaling regulates the expression of insulin‐like growth factor binding protein‐6 during fetal prostate development
2005
Prostate Development Requires Sonic Hedgehog Expressed by the Urogenital Sinus Epithelium
1999
Response-Specific and Ligand Dose-Dependent Modulation of Estrogen Receptor (ER) α Activity by ERβ in the Uterus
2003
Sonic Hedgehog Activates Mesenchymal Gli1 Expression during Prostate Ductal Bud Formation
2002
Estrogen Receptor Regulation of Carbonic Anhydrase XII through a Distal Enhancer in Breast Cancer
2008
The Human Prostate Expresses Sonic Hedgehog During Fetal Development
2002
Transcriptional Profiling of Estrogen-Regulated Gene Expression via Estrogen Receptor (ER) α or ERβ in Human Osteosarcoma Cells: Distinct and Common Target Genes for These Receptors
2004