Citation Impact
Citing Papers
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
Deletion of CTLA-4 on regulatory T cells during adulthood leads to resistance to autoimmunity
2015
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Nanog Is the Gateway to the Pluripotent Ground State
2009 StandoutNobel
The impact of rare and low-frequency genetic variants in common disease
2017
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
The interleukin-6 receptor Asp358Ala single nucleotide polymorphism rs2228145 confers increased proteolytic conversion rates by ADAM proteases
2014
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Treg and CTLA-4: Two intertwining pathways to immune tolerance
2013
Validated germline-competent embryonic stem cell lines from nonobese diabetic mice
2009
Coinhibitory Pathways in the B7-CD28 Ligand-Receptor Family
2016
Co-stimulatory and Co-inhibitory Pathways in Autoimmunity
2016
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
2009 Standout
Genome-wide association studies for complex traits: consensus, uncertainty and challenges
2008 Standout
Intrinsic and extrinsic control of peripheral T‐cell tolerance by costimulatory molecules of the CD28/ B7 family
2011
Widespread seasonal gene expression reveals annual differences in human immunity and physiology
2015
Antibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes
2016 StandoutNobel
IL-6 as a keystone cytokine in health and disease
2015 Standout
Kidney injuries related to ipilimumab
2014
Adverse Renal Effects of Immune Checkpoint Inhibitors: A Narrative Review
2017 Standout
Nuclear Transfer and iPS May Work Best Together
2008 StandoutNobel
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
2011
Regulatory T cells in cancer immunotherapy
2016 StandoutNobel
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Chapter 6 Gene–Gene Interactions in the NOD Mouse Model of Type 1 Diabetes
2008
Type 1 diabetes
2013 Standout
Derivation of pluripotent epiblast stem cells from mammalian embryos
2007 StandoutNature
Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation
2016 Standout
New cell lines from mouse epiblast share defining features with human embryonic stem cells
2007 StandoutNature
Gene Map of the HLA Region, Graves’ Disease and Hashimoto Thyroiditis, and Hematopoietic Stem Cell Transplantation
2015
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Regulatory T Cell-Specific Epigenomic Region Variants Are a Key Determinant of Susceptibility to Common Autoimmune Diseases
2020 StandoutNobel
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
2018 Standout
A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
2013 StandoutNobel
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Human FOXP3+ Regulatory T Cell Heterogeneity and Function in Autoimmunity and Cancer
2019 StandoutNobel
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
2007
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Genetic and epigenetic basis of Treg cell development and function: from a FoxP3‐centered view to an epigenome‐defined view of natural Treg cells
2014 StandoutNobel
Regulatory T Cells and Human Disease
2020 StandoutNobel
Targeting Treg cells in cancer immunotherapy
2019 StandoutNobel
Alloantigen-specific regulatory T cells generated with a chimeric antigen receptor
2016
Histone variant macroH2A confers resistance to nuclear reprogramming
2011 StandoutNobel
CTLA-4 blockade in tumor models: an overview of preclinical and translational research.
2013
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
2018 StandoutNobel
Genetic and epigenetic variation in the lineage specification of regulatory T cells
2015
Tyrosine 201 of the cytoplasmic tail of CTLA ‐4 critically affects T regulatory cell suppressive function
2014
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Control of foreign Ag‐specific Ab responses by Treg and Tfr
2020 StandoutNobel
Derivation of germ-line-competent embryonic stem cell lines from preblastocyst mouse embryos
2005
A Transendocytosis Model of CTLA-4 Function Predicts Its Suppressive Behavior on Regulatory T Cells
2015
Proenkephalin+regulatory T cells expanded by ultraviolet B exposure maintain skin homeostasis with a healing function
2020 StandoutNobel
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
CD4+CD45RA−FoxP3high activated regulatory T cells are functionally impaired and related to residual insulin-secreting capacity in patients with type 1 diabetes
2013
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Cutting Edge: Chronic Inflammatory Liver Disease in Mice Expressing a CD28-Specific Ligand
2012 StandoutNobel
Induced pluripotent stem cells: opportunities and challenges
2011 StandoutNobel
Immune Checkpoint Blockade in Cancer Therapy
2015 Standout
Regulatory T cells expressing abundant CTLA‐4 on the cell surface with a proliferative gene profile are key features of human head and neck cancer
2018 StandoutNobel
Cutting Edge: CTLA-4 on Effector T Cells Inhibits In Trans
2012 StandoutNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Works of Daniel B. Rainbow being referenced
Genetic Evidence That the Differential Expression of the Ligand-Independent Isoform of CTLA-4 Is the Molecular Basis of the Idd5.1 Type 1 Diabetes Region in Nonobese Diabetic Mice
2009
Development of an integrated genome informatics, data management and workflow infrastructure: A toolbox for the study of complex disease genetics
2004
Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity
2017
Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases
2013
Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles
2014
Genetic Control of Autoimmunity: Protection from Diabetes, but Spontaneous Autoimmune Biliary Disease in a Nonobese Diabetic Congenic Strain
2004
Genome-Wide Microarray Expression Analysis of CD4+ T Cells from Nonobese Diabetic Congenic Mice Identifies Cd55 (Daf1) and Acadl as Candidate Genes for Type 1 Diabetes
2008
Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing
2015
The B10 Idd9.3 Locus Mediates Accumulation of Functionally Superior CD137+ Regulatory T Cells in the Nonobese Diabetic Type 1 Diabetes Model
2012
Overexpression of the CTLA-4 Isoform Lacking Exons 2 and 3 Causes Autoimmunity
2011
NOD.c3c4 congenic mice develop autoimmune biliary disease that serologically and pathogenetically models human primary biliary cirrhosis
2006
The Derivation of Highly Germline-Competent Embryonic Stem Cells Containing NOD-Derived Genome
2003
Nonobese Diabetic Congenic Strain Analysis of Autoimmune Diabetes Reveals Genetic Complexity of the Idd18 Locus and Identifies Vav3 as a Candidate Gene
2010
The Soluble CTLA-4 Splice Variant Protects From Type 1 Diabetes and Potentiates Regulatory T-Cell Function
2011