Citation Impact
Citing Papers
Protein interaction networks revealed by proteome coevolution
2019 StandoutScienceNobel
Novel D761Y and Common Secondary T790M Mutations in Epidermal Growth Factor Receptor–Mutant Lung Adenocarcinomas with Acquired Resistance to Kinase Inhibitors
2006
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
2007 StandoutScience
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Addition of a photocrosslinking amino acid to the genetic code of Escherichia coli
2002
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Structural basis for the recognition of SARS-CoV-2 by full-length human ACE2
2020 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Regulation of progression through the Gl phase of the cell cycle by the rum1+ gene
1994 StandoutNatureNobel
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
M-Ras/R-Ras3, a Transforming Ras Protein Regulated by Sos1, GRF1, and p120 Ras GTPase-activating Protein, Interacts with the Putative Ras Effector AF6
1999
Lethality and centrality in protein networks
2001 StandoutNature
Anaplastic lymphoma kinase proteins in growth control and cancer
2004
Dual-specificity protein kinases: will any hydroxyl do?
1992
Inhibition of CDK1 as a potential therapy for tumors over-expressing MYC
2007 Nobel
Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer
2007 StandoutNature
The generation of diversity and pattern in animal development
1992 StandoutNobel
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus
2003 StandoutNature
Bcr–Abl variants: biological and clinical aspects
2002
Oncoprotein Networks
1997
When Checkpoints Fail
1997 StandoutNobel
Synaptic transmission: A bidirectional and self-modifiable form of cell-cell communication
1993 StandoutNobel
DIP: the Database of Interacting Proteins
2000
The Hallmarks of Cancer
2000 Standout
TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology
2012
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
A Serpin Shapes the Extracellular Environment to Prevent Influenza A Virus Maturation
2015 StandoutNobel
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Dissection of the protein kinase cascade by which nerve growth factor activates MAP kinases
1991 Nature
The c‐myc Promoter: Still MysterY and Challenge
2007
A distinct molecular profile associated with mucinous epithelial ovarian cancer
2006
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
2019
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
2005
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Reflecting on 25 years with MYC
2008 Standout
Molecular genetics, natural history and the demise of childhood leukaemia
1999
The Primary Immunodeficiencies
1995
Imaging Hematopoietic Precursor Division in Real Time
2007
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Transient Receptor Potential Cation Channels in Disease
2007 Standout
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Expression cloning of an activin receptor, a predicted transmembrane serine kinase
1991
Pervasive Adaptive Evolution in Primate Seminal Proteins
2005
Granulocyte–Macrophage Progenitors as Candidate Leukemic Stem Cells in Blast-Crisis CML
2004
BCR-ABL point mutants isolated from patients with imatinib mesylate–resistant chronic myeloid leukemia remain sensitive to inhibitors of the BCR-ABL chaperone heat shock protein 90
2002
Hidden Markov models of biological primary sequence information.
1994 StandoutNobel
SPK1 is an essential S-phase-specific gene of Saccharomyces cerevisiae that encodes a nuclear serine/threonine/tyrosine kinase.
1993
Protein Tyrosine Phosphatases: A Diverse Family of Intracellular and Transmembrane Enzymes
1991 Science
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Proteolytic Activation of Influenza Viruses by Serine Proteases TMPRSS2 and HAT from Human Airway Epithelium
2006
Novel interferon-β-induced gene expression in peripheral blood cells
2007
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
1999 StandoutScience
Cytokinetic failure and asynchronous nuclear division in BHK cells overexpressing a truncated protein-tyrosine-phosphatase.
1992 StandoutNobel
Small GTP-Binding Proteins
2001 Standout
SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade
2008 StandoutNobel
Tyrosine phosphorylation and activation of homologous protein kinases during oocyte maturation and mitogenic activation of fibroblasts.
1991
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
c-Myc Target Genes Involved in Cell Growth, Apoptosis, and Metabolism
1999
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.
1994
Regulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fate
2000
Phenotypic Analysis of Mice Lacking the Tmprss2-Encoded Protease
2006
Illegitimate Cre-dependent chromosome rearrangements in transgenic mouse spermatids
2000 StandoutNobel
A Transmembrane Serine Protease Is Linked to the Severe Acute Respiratory Syndrome Coronavirus Receptor and Activates Virus Entry
2010
Murine six-transmembrane epithelial antigen of the prostate, prostate stem cell antigen, and prostate-specific membrane antigen: prostate-specific cell-surface antigens highly expressed in prostate cancer of transgenic adenocarcinoma mouse prostate mice.
2001
Structure of the Ets-1 pointed domain and mitogen-activated protein kinase phosphorylation site
1998
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Activation of PI3K/Akt and MAPK pathways regulates Myc-mediated transcription by phosphorylating and promoting the degradation of Mad1
2008
TEL/AML-1 dimerizes and is associated with a favorable outcome in childhood acute lymphoblastic leukemia
1996
The t(1;12)(q21;p13) translocation of human acute myeloblastic leukemia results in a TEL-ARNT fusion
2000
The Steap proteins are metalloreductases
2006
Repeated pulses of serotonin required for long-term facilitation activate mitogen-activated protein kinase in sensory neurons of Aplysia
1998 StandoutNobel
Cancer Genome Landscapes
2013 StandoutScience
Definition of a consensus sequence for peptide substrate recognition by p44mpk, the meiosis-activated myelin basic protein kinase
1991
Yeast spindle pole body duplication gene MPS1 encodes an essential dual specificity protein kinase.
1995
Microtubule-associated protein 2 kinases, ERK1 and ERK2, undergo autophosphorylation on both tyrosine and threonine residues: implications for their mechanism of activation.
1991
Mutations in mouse Aspm (abnormal spindle-like microcephaly associated) cause not only microcephaly but also major defects in the germline
2010 StandoutNobel
Redirecting tyrosine kinase signaling to an apoptotic caspase pathway through chimeric adaptor proteins
2003
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Several members of the mouse carcinoembryonic antigen-related glycoprotein family are functional receptors for the coronavirus mouse hepatitis virus-A59
1993
Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition
2007
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
De novo design of protein logic gates
2020 StandoutScienceNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis
2003 StandoutNobel
Works of Daniel Afar being referenced
Regulation of the Oncogenic Activity of BCR-ABL by a Tightly Bound Substrate Protein RIN1
1997
Regulation of Btk Function by a Major Autophosphorylation Site Within the SH3 Domain
1996
Differential Complementation of Bcr-Abl Point Mutants with c-Myc
1994 Science
Genetic Approaches to Defining Signaling by the CML-associated Tyrosine Kinase BCR-ABL
1994
Bcl-2-independent Bcr–Abl-mediated resistance to apoptosis: protection is correlated with up regulation of Bcl-xL
1998
Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene
1995
A Point Mutation in the SH2 Domain of Bruton's Tyrosine Kinase in Atypical X-Linked Agammaglobulinemia
1994
The Dimerization Property of Glutathione -Transferase Partially Reactivates Bcr-Abl Lacking the Oligomerization Domain
1996
Multiple cDNAs Encoding the esk Kinase Predict Transmembrane and Intracellular Enzyme Isoforms
1992
STY, a Tyrosine-Phosphorylating Enzyme with Sequence Homology to Serine/Threonine Kinases
1991
Signaling by ABL oncogenes through cyclin D1.
1995
Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse.
2003
Oligomerization of the ABL Tyrosine Kinase by the Ets Protein TEL in Human Leukemia
1996
Multiple cDNAs encoding the esk kinase predict transmembrane and intracellular enzyme isoforms.
1992
Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.
2001
STY, a tyrosine-phosphorylating enzyme with sequence homology to serine/threonine kinases.
1991
Identification of tyrosine 620 as the major phosphorylation site of myelin-associated glycoprotein and its implication in interacting with signaling molecules.
1994
Protein binding and signaling properties of RIN1 suggest a unique effector function
1997
A mouse analogue of the human carcinoembryonic antigen.
1989
Transcriptional activation of a ras-like gene (kir) by oncogenic tyrosine kinases.
1994
Epithelial membrane protein-1 is a biomarker of gefitinib resistance
2005
Genetic Approaches to Defining Signaling by the CML-Associated Tyrosine kinase BCR-ABL1
1996
STEAP: A prostate-specific cell-surface antigen highly expressed in human prostate tumors
1999