Citation Impact
Citing Papers
HIV-1/ Mycobacterium tuberculosis Coinfection Immunology: How Does HIV-1 Exacerbate Tuberculosis?
2011
The Pathogen Candida albicans Hijacks Pyroptosis for Escape from Macrophages
2014
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
2016
Caspase‐11 activates a canonical NLRP3 inflammasome by promoting K + efflux
2015
Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes
2015
IL-1–induced Bhlhe40 identifies pathogenic T helper cells in a model of autoimmune neuroinflammation
2016
PD-1 expression by tumour-associated macrophages inhibits phagocytosis and tumour immunity
2017 StandoutNature
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
2020
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation
2015 StandoutNobel
Caspase-11 and caspase-1 differentially modulate actin polymerization via RhoA and Slingshot proteins to promote bacterial clearance
2015
Caspase-1 initiates apoptosis in the absence of gasdermin D
2019
PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
2016
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Necroptosis and its role in inflammation
2015 StandoutNature
Syndemics and the biosocial conception of health
2017 Standout
Inflammation and Cancer: Triggers, Mechanisms, and Consequences
2019 Standout
Mechanisms of NOD-like Receptor-Associated Inflammasome Activation
2013
Bacterial Exotoxins and the Inflammasome
2015
COPs and POPs Patrol Inflammasome Activation
2017
Converging roles of caspases in inflammasome activation, cell death and innate immunity
2015
Mechanism and Regulation of NLRP3 Inflammasome Activation
2016 Standout
The NLRP3 inflammasome: molecular activation and regulation to therapeutics
2019 Standout
The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome
2018
Tuberculosis and HIV Co-Infection
2012
Hallmarks of aging: An expanding universe
2023 Standout
Molecular mechanisms regulating NLRP3 inflammasome activation
2015 Standout
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Inflammasome Complexes: Emerging Mechanisms and Effector Functions
2016
The M1 and M2 paradigm of macrophage activation: time for reassessment
2014 Standout
The transcription factor IRF1 and guanylate-binding proteins target activation of the AIM2 inflammasome by Francisella infection
2015
The biology and function of fibroblasts in cancer
2016 Standout
Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock
2015
Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases
2014 Nature
Immunogenic cell death in cancer and infectious disease
2016 Standout
Reactive Oxygen Species Regulate Caspase-11 Expression and Activation of the Non-canonical NLRP3 Inflammasome during Enteric Pathogen Infection
2014
The molecular machinery of regulated cell death
2019 Standout
Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium
2015
Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation
2016
Cellular senescence in ageing: from mechanisms to therapeutic opportunities
2020 Standout
IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes
2016
Mechanisms of inflammasome activation: recent advances and novel insights
2015
Salmonellae interactions with host processes
2015
Differential roles of caspase-1 and caspase-11 in infection and inflammation
2017
A long-awaited merger of the pathways mediating host defence and programmed cell death
2014
Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice
2015
Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death
2016
Bacterial virulence factor inhibits caspase-4/11 activation in intestinal epithelial cells
2016
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
Inflammasomes: mechanism of assembly, regulation and signalling
2016 Standout
HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers
2018
Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
2018
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Non-canonical inflammasome activation targets caspase-11
2011 StandoutNature
Inflammatory caspases are innate immune receptors for intracellular LPS
2014 StandoutNature
NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux
2016 Nature
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
2014
Non-canonical activation of inflammatory caspases by cytosolic LPS in innate immunity
2015
Gut microbiota, metabolites and host immunity
2016 Standout
Mechanisms and Functions of Inflammasomes
2014 Standout
Induction of human humoral immune responses in a novel HLA-DR-expressing transgenic NOD/Shi-scid/ cnull mouse
2012
Cryptopatches Are Essential for the Development of Human GALT
2013
Microbicides for HIV prevention: reality or hope?
2009
Mitochondria as multifaceted regulators of cell death
2019 Standout
Caspases Connect Cell-Death Signaling to Organismal Homeostasis
2016
Humanized mice for immune system investigation: progress, promise and challenges
2012
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
2016 Standout
Caspase crosstalk: integration of apoptotic and innate immune signalling pathways
2014
The oxidized phospholipid oxPAPC protects from septic shock by targeting the non-canonical inflammasome in macrophages
2018
Diverse mechanisms for inflammasome sensing of cytosolic bacteria and bacterial virulence
2015
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Inflammasomes: mechanism of action, role in disease, and therapeutics
2015 Standout
HIV-1 Neutralization Profile and Plant-Based Recombinant Expression of Actinohivin, an Env Glycan-Specific Lectin Devoid of T-Cell Mitogenic Activity
2010 StandoutNobel
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
2015 Standout
Evaluation of antiretrovirals in animal models of HIV infection
2009
Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis
2021 StandoutNobel
An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology
2013
Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens
2014
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida
2015
NF-κB Regulates PD-1 Expression in Macrophages
2015
Inflammasome Activation by Adenylate Cyclase Toxin Directs Th17 Responses and Protection against Bordetella pertussis
2010
Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing
2013 StandoutNobel
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
2016
Complement pathway amplifies caspase-11–dependent cell death and endotoxin-induced sepsis severity
2016
cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis
2019
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
2017 Standout
Guanylate Binding Proteins Enable Rapid Activation of Canonical and Noncanonical Inflammasomes in Chlamydia-Infected Macrophages
2015
Lipid Nanoparticles Delivering Constitutively Active STING mRNA to Stimulate Antitumor Immunity
2022 StandoutNobel
The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 Standout
Post-translational regulation of inflammasomes
2016
Caspase-11 Modulates Inflammation and AttenuatesToxoplasma gondiiPathogenesis
2016
Pyroptotic cell death defends against intracellular pathogens
2015
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Gasdermins and their role in immunity and inflammation
2019
Infectious diseases in humanized mice
2013
The Future of HIV Microbicides: Challenges and Opportunities
2009
Caspase‐4 mediates non‐canonical activation of the NLRP3 inflammasome in human myeloid cells
2015
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5
2015
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Caspase‐11: arming the guards against bacterial infection
2015
Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice
2009
Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS
2014
Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2rγnullhumanized mice
2010
Human NLRP3 inflammasome senses multiple types of bacterial RNAs
2014
Characterization of Human Antiviral Adaptive Immune Responses during Hepatotropic Virus Infection in HLA-Transgenic Human Immune System Mice
2013 StandoutNobel
Human caspase-4 mediates noncanonical inflammasome activation against gram-negative bacterial pathogens
2015
Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation
2018
Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor–, granulocyte-macrophage colony-stimulating factor–, and interleukin-3–expressing NOD-SCID IL2Rγnull humanized mice
2011 StandoutNobel
Regulation of inflammasome activation
2015
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
A Critical Role for Human Caspase-4 in Endotoxin Sensitivity
2014
TRP Channels as Sensors of Chemically-Induced Changes in Cell Membrane Mechanical Properties
2019
Humanized mouse models of HIV infection.
2011
Caspase-1 but Not Caspase-11 Is Required for NLRC4-Mediated Pyroptosis and Restriction of Infection by Flagellated Legionella Species in Mouse Macrophages and In Vivo
2015
Protective Role for Caspase-11 during Acute Experimental Murine Colitis
2014
Works of Daniel A. Powell being referenced
LPS remodeling is an evolved survival strategy for bacteria
2012
Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock
2013 Science
Antiretroviral Pre-exposure Prophylaxis Prevents Vaginal Transmission of HIV-1 in Humanized BLT Mice
2008
Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice
2010
Pertussis Toxin Stimulates IL-17 Production in Response to Bordetella pertussis Infection in Mice
2009
One Percent Tenofovir Applied Topically to Humanized BLT Mice and Used According to the CAPRISA 004 Experimental Design Demonstrates Partial Protection from Vaginal HIV Infection, Validating the BLT Model for Evaluation of New Microbicide Candidates
2011
Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice
2020