Standout Papers
Citation Impact
Citing Papers
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
A Genomic Map of p53 Binding Sites Identifies Novel p53 Targets Involved in an Apoptotic Network
2005
Effects of Parathyroid Hormone Treatment on Circulating Sclerostin Levels in Postmenopausal Women
2010
Nuclear factor-κB signaling and ezrin are essential for L1-mediated metastasis of colon cancer cells
2010
NOTCH Signaling Is Required for Formation and Self-Renewal of Tumor-Initiating Cells and for Repression of Secretory Cell Differentiation in Colon Cancer
2010 StandoutNobel
Comparative Genome Analysis Identifies the Vitamin D Receptor Gene as a Direct Target of p53-Mediated Transcriptional Activation
2006
Energy Management by Enhanced Glycolysis in G1-phase in Human Colon Cancer Cells In Vitro and In Vivo
2013
Use of the zero norm with linear models and kernel methods
2003
APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis.
2001
STATISTICAL METHODS FOR IDENTIFYING DIFFERENTIALLY EXPRESSED GENES IN REPLICATED cDNA MICROARRAY EXPERIMENTS
2002
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
An extensive comparison of recent classification tools applied to microarray data
2004
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
Tests for finding complex patterns of differential expression in cancers: towards individualized medicine
2004
Autophagy Suppresses Tumorigenesis through Elimination of p62
2009
Breast cancer stem cells: treatment resistance and therapeutic opportunities
2011
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Gene selection: a Bayesian variable selection approach
2002
p53RFP, a p53-inducible RING-finger protein, regulates the stability of p21WAF1
2003
Systematic variation in gene expression patterns in human cancer cell lines
2000 Standout
Regulation of p53 activity by its interaction with homeodomain-interacting protein kinase-2
2001
p53: traffic cop at the crossroads of DNA repair and recombination
2005
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
Biomarker Identification by Feature Wrappers
2001
Identification of a Novel p53 Functional Domain That Is Necessary for Mediating Apoptosis
1998
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
New feature subset selection procedures for classification of expression profiles
2002
High-Resolution Mapping Reveals a Conserved, Widespread, Dynamic mRNA Methylation Program in Yeast Meiosis
2013 StandoutNobel
Transcriptional activation of the human stress-inducible transcriptional repressor ATF3 gene promoter by p53
2002
Transcriptional Regulation by p53 through Intrinsic DNA/Chromatin Binding and Site-Directed Cofactor Recruitment
2001
Filter versus wrapper gene selection approaches in DNA microarray domains
2004
Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation
2002 Standout
Genomics, gene expression and DNA arrays
2000 Nature
Feature extraction and normalization algorithms for high-density oligonucleotide gene expression array data
2001
The expanding universe of p53 targets
2009
Gene selection for sample classification based on gene expression data: study of sensitivity to choice of parameters of the GA/KNN method
2001
Negative Regulation of Chk2 Expression by p53 Is Dependent on the CCAAT-binding Transcription Factor NF-Y
2004
Linking L1CAM-mediated signaling to NF-κB activation
2010
p21/CDKN1A Mediates Negative Regulation of Transcription by p53
2003
Gene selection from microarray data for cancer classification—a machine learning approach
2005
Apoptosis regulators and their role in tumorigenesis
2001
p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage
2000
Does osteocytic SOST suppression mediate PTH bone anabolism?
2010
The Hallmarks of Cancer
2000 Standout
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Gene expression patterns associated with p53 status in breast cancer
2006
Identification of genes expressed in C. elegans touch receptor neurons
2002 StandoutNatureNobel
DNA microarrays identification of primary and secondary target genes regulated by p53
2001
WNT signaling in bone homeostasis and disease: from human mutations to treatments
2013 Standout
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
The Phosphatase MKP1 Is a Transcriptional Target of p53 Involved in Cell Cycle Regulation
2003
Regulation of PTEN Transcription by p53
2001
p53 Has a Direct Apoptogenic Role at the Mitochondria
2003
GLS2 is transcriptionally regulated by p73 and contributes to neuronal differentiation
2013
The P53 pathway: what questions remain to be explored?
2006
Membrane Fusion
2003 StandoutNobel
p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers
2006
Direct Transcriptional Activation of Human Caspase-1 by Tumor Suppressor p53
2001
A Bayesian framework for the analysis of microarray expression data: regularized t -test and statistical inferences of gene changes
2001
Live or let die: the cell's response to p53
2002 Standout
On the statistical assessment of classifiers using DNA microarray data
2006
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Molecular portraits of human breast tumours
2000 StandoutNature
Defining transcription modules using large-scale gene expression data
2004
The function of PML in p53-dependent apoptosis
2000
Regulation of p53 Stability and Function in HCT116 Colon Cancer Cells
2004
Receptor tyrosine kinase EphA2 is regulated by p53-family proteins and induces apoptosis
2001
Genetic algorithms applied to multi-class prediction forthe analysis of gene expression data
2002
An Efficient and Robust Statistical Modeling Approach to Discover Differentially Expressed Genes Using Genomic Expression Profiles
2001
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer
2013 Standout
Multiclass classification of microarray data with repeated measurements: application to cancer
2003
Large-Scale Clustering of cDNA-Fingerprinting Data
1999
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
2012 Nature
p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas
2002
Cancer-related inflammation
2008 StandoutNature
Control of apoptosis by p53
2003
Microarray Expression Profiling Identifies Genes with Altered Expression in HDL-Deficient Mice
2000
Gene selection and classification of microarray data using random forest
2006 Standout
Molecular portraits and the family tree of cancer
2002
Bayesian model averaging: development of an improved multi-class, gene selection and classification tool for microarray data
2005
Global transcriptional program of p53 target genes during the process of apoptosis and cell cycle progression
2003
WISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinase
2002
Heterogeneous expression of Wnt/β‐catenin target genes within colorectal cancer
2007
The first 30 years of p53: growing ever more complex
2009 Standout
The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene
1999
Redox control of glutamine utilization in cancer
2014
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
Support vector machine classification and validation of cancer tissue samples using microarray expression data
2000 Standout
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Transcriptional Repression of the Anti-apoptoticsurvivin Gene by Wild Type p53
2002
The origins and the future of microfluidics
2006 StandoutNature
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
2002 Standout
Clustering Gene Expression Patterns
1999
Tissue Classification with Gene Expression Profiles
2000
Machine learning: Trends, perspectives, and prospects
2015 StandoutScience
Model-Based Clustering, Discriminant Analysis, and Density Estimation
2002 Standout
Circadian clock disruption improves the efficacy of chemotherapy through p73-mediated apoptosis
2011 StandoutNobel
Singular value decomposition for genome-wide expression data processing and modeling
2000
Differential Transactivation by the p53 Transcription Factor Is Highly Dependent on p53 Level and Promoter Target Sequence
2002
p53CSV, a Novel p53-Inducible Gene Involved in the p53-Dependent Cell-Survival Pathway
2005
Identification and Classification of Differentially Expressed Genes in Renal Cell Carcinoma by Expression Profiling on a Global Human 31,500-Element cDNA Array
2001
Linking gene expression patterns to therapeutic groups in breast cancer.
2000
Oncogenic ras and p53 Cooperate To Induce Cellular Senescence
2002
Model-based analysis of oligonucleotide arrays: Expression index computation and outlier detection
2000 Standout
L1-Mediated Colon Cancer Cell Metastasis Does Not Require Changes in EMT and Cancer Stem Cell Markers
2010
The p53MH algorithm and its application in detecting p53-responsive genes
2002
The Regulation of Exosome Secretion: a Novel Function of the p53 Protein
2006
Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53
2002
Comparison of Methods for Image Analysis on cDNA Microarray Data
2002
A comparative study on feature selection and classification methods using gene expression profiles and proteomic patterns.
2002
Anabolic and Catabolic Regimens of Human Parathyroid Hormone 1–34 Elicit Bone- and Envelope-Specific Attenuation of Skeletal Effects in Sost-Deficient Mice
2011
Downregulation ofGLS2in glioblastoma cells is related to DNA hypermethylation but not to the p53 status
2015
Identifying marker genes in transcription profiling data using a mixture of feature relevance experts
2001
Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer
2001
Regularized ROC method for disease classification and biomarker selection with microarray data
2005
Predicting the clinical status of human breast cancer by using gene expression profiles
2001
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Incremental wrapper-based gene selection from microarray data for cancer classification
2005
Transcriptional control of human p53-regulated genes
2008 Standout
Aneuploidy: Cells Losing Their Balance
2008
Ordering Genes in a Flagella Pathway by Analysis of Expression Kinetics from Living Bacteria
2001 Science
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses
2001 Standout
Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study
2000
Multiple Hypothesis Testing in Microarray Experiments
2003
Physics and Applications of Microfluidics in Biology
2002
Surfing the p53 network
2000 StandoutNature
MINIMUM REDUNDANCY FEATURE SELECTION FROM MICROARRAY GENE EXPRESSION DATA
2005 Standout
Class prediction and discovery using gene microarray andproteomics mass spectroscopy data: curses, caveats, cautions
2003
Cancer Genome Landscapes
2013 StandoutScience
Myc promotes glutaminolysis in human neuroblastoma through direct activation of glutaminase 2
2015
Efficient Specific DNA Binding by p53 Requires both Its Central and C-Terminal Domains as Revealed by Studies with High-Mobility Group 1 Protein
2002
Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome.
2000
Analyzing gene expression data in terms of gene sets: methodological issues
2007
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Optimal detection of sparse principal components in high dimension
2013
p53-Mediated Apoptosis and Genomic Instability Diseases
2001
The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting
2003
Comparison of Discrimination Methods for the Classification of Tumors Using Gene Expression Data
2002 Standout
The N-Terminal Domain of p73 Interacts with the CH1 Domain of p300/CREB Binding Protein and Mediates Transcriptional Activation and Apoptosis
2000
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
GENE SELECTION FOR CANCER CLASSIFICATION USING WRAPPER APPROACHES
2004
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Part 14: Pediatric Advanced Life Support
2010 Standout
The CDK7-cycH-p36 Complex of Transcription Factor IIH Phosphorylates p53, Enhancing Its Sequence-Specific DNA Binding Activity In Vitro
1997
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Poly(dimethylsiloxane) as a Material for Fabricating Microfluidic Devices
2002 Standout
Gene Selection for Cancer Classification using Support Vector Machines
2002 Standout
A review of feature selection techniques in bioinformatics
2007 Standout
Selection bias in gene extraction on the basis of microarray gene-expression data
2002
Chromatin Immunoprecipitation-Based Screen To Identify Functional Genomic Binding Sites for Sequence-Specific Transactivators
2005
Works of Daniel A. Notterman being referenced
CpG Island Methylator Phenotype Associates with Low-Degree Chromosomal Abnormalities in Colorectal Cancer
2008
γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity
2009
Expression of L1-CAM and ADAM10 in Human Colon Cancer Cells Induces Metastasis
2007
Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer
2006
Pharmacokinetics of Cardiovascular Drugs in Children
1994
The Transcriptional Program following p53 Activation
2000
PHARMACOLOGY OF PEDIATRIC RESUSCITATION
1997
Determination of Dual Effects of Parathyroid Hormone on Skeletal Gene Expression in Vivo by Microarray and Network Analysis
2007
Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
1999 Standout
Dielectric spectroscopy for bioanalysis: From 40 Hz to 26.5 GHz in a microfabricated wave guide
2001
Expression of Wild-Type α-Catenin Protein in Cells with a Mutant α-Catenin Gene Restores Both Growth Regulation and Tumor Suppressor Activities
1997
The p53 tumor suppressor gene.
1994
Transcriptional gene expression profiles of colorectal adenoma, adenocarcinoma, and normal tissue examined by oligonucleotide arrays.
2001
Analysis of p53-regulated gene expression patterns using oligonucleotide arrays
2000
p63 regulates glutaminase 2 expression
2013
Capacitance cytometry: Measuring biological cells one by one
2000