Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
The role of dynamic conformational ensembles in biomolecular recognition
2009 Standout
Mechanisms of Caspase Activation and Inhibition during Apoptosis
2002 Standout
Evolutionary conservation in protein folding kinetics
2000 StandoutNobel
Apoptosis in cancer
2000 Standout
An Induced Proximity Model for Caspase-8 Activation
1998
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Synthetic glycobiology: exploits in the Golgi compartment
2006 StandoutNobel
Smad transcription factors
2005 Standout
Multi-input chemical control of protein dimerization for programming graded cellular responses
2019 StandoutNobel
Caspases: pharmacological manipulation of cell death
2005 Standout
The atomic structure of protein-protein recognition sites 1 1Edited by A. R. Fersht
1999 Standout
TGF-β signaling in tumor suppression and cancer progression
2001 Standout
FK506 and cyclosporin, molecular probes for studying intracellular signal transduction
1993
TGF-β signalling from cell membrane to nucleus through SMAD proteins
1997 StandoutNature
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Identification of Smad7, a TGFβ-inducible antagonist of TGF-β signalling
1997 StandoutNature
Peptidylproline cis‐trans‐isomerases: immunophilins
1993
TOR Mutations Confer Rapamycin Resistance by Preventing Interaction with FKBP12-Rapamycin
1995
Three-Dimensional Solution Structure of Escherichia coli Periplasmic Cyclophilin
1994
The biochemistry of apoptosis
2000 StandoutNature
Tor, a Phosphatidylinositol Kinase Homologue, Controls Autophagy in Yeast
1998 StandoutNobel
A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva
2006 Standout
15N NMR Relaxation Studies of the FK506 Binding Protein: Dynamic Effects of Ligand Binding and Implications for Calcineurin Recognition
1994
Mechanism of TGFβ receptor inhibition by FKBP12
1997
Apop-1, a Novel Protein Inducing Cyclophilin D-dependent but Bax/Bak-related Channel-independent Apoptosis
2006 StandoutNobel
Rescue of Degradation‐Prone Mutants of the FK506‐Rapamycin Binding (FRB) Protein with Chemical Ligands
2007 StandoutNobel
Caspase Functions in Cell Death and Disease
2013 Standout
Differential Responses of the Backbone and Side-Chain Conformational Dynamics in FKBP12 upon Binding the Transition-State Analog FK506: Implications for Transition-State Stabilization and Target Protein Recognition
2009
The NMR solution conformation of unligated human cyclophilin A 1 1Edited by P. E. Wright
1997 StandoutNobel
Signaling—2000 and Beyond
2000 Standout
A mechanism for rotamase catalysis by the FK506 binding protein (FKBP)
1993
Regulation of the Calmodulin-stimulated Protein Phosphatase, Calcineurin
1998
Two TOR Complexes, Only One of which Is Rapamycin Sensitive, Have Distinct Roles in Cell Growth Control
2002 Standout
Probing the role of homomeric and heteromeric receptor interactions in TGF-β signaling using small molecule dimerizers
1998
Role of Extracellular ATP and P1 and P2 Classes of Purinergic Receptors in T‐cell Development and Cytotoxic T Lymphocyte Effector Functions
1995 StandoutNobel
Drug target validation and identification of secondary drug target effects using DNA microarrays
1998 StandoutNobel
A Novel FK506 Binding Protein Can Mediate the Immunosuppressive Effects of FK506 and Is Associated with the Cardiac Ryanodine Receptor
1995
XTrR-I is a TGFβ receptor and overexpression of a truncated form of the receptor inhibits axis formation and dorsalising activity
1998 StandoutNobel
Cell-growth control by monomeric antigen: the cell surface expression of lysozyme-specific Ig V-domains fused to truncated Epo receptor
2000 StandoutNobel
FK506 Binding Protein Mutational Analysis
1995
Molecular mechanisms of caspase regulation during apoptosis
2004 Standout
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
The mitochondrial permeability transition
1995 Standout
Chemical approaches to the investigation of cellular systems
2002 StandoutNobel
Structure comparison of native and mutant human recombinant FKBP12 complexes with the immunosuppressant drug FK506 (tacrolimus)
1995
X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex
1995
The Immunophilin FKBP12 Functions as a Common Inhibitor of the TGFβ Family Type I Receptors
1996
Conformational polymorphism of cyclosporin A
1994 StandoutNobel
PKA Phosphorylation Dissociates FKBP12.6 from the Calcium Release Channel (Ryanodine Receptor)
2000 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Steroid Receptor Interactions with Heat Shock Protein and Immunophilin Chaperones*
1997 Standout
TGF-β SIGNAL TRANSDUCTION
1998 Standout
Conditional Glycosylation in Eukaryotic Cells Using a Biocompatible Chemical Inducer of Dimerization
2008 StandoutNobel
The affinity of the excised binding domain of FK-506 for the immunophilin FKBP12.
1993
High-affinity FKBP-12 ligands derived from (R)-(−)-carvone. Synthesis and evaluation of FK506 pyranose ring replacements
1995
Fkbp51, a Novel T-Cell-Specific Immunophilin Capable of Calcineurin Inhibition
1995
Structure-Based Design of a Cyclophilin-Calcineurin Bridging Ligand
1993 Science
NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation
1998 StandoutScience
The immunophilins
1994
Death Receptors: Signaling and Modulation
1998 StandoutScience
The mitochondrial permeability transition pore and its role in cell death
1999 Standout
Biochemical Pathways of Caspase Activation During Apoptosis
1999 Standout
The Future of Golgi Research
2010 StandoutNobel
TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function
1997 Standout
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Mammalian Caspases: Structure, Activation, Substrates, and Functions During Apoptosis
1999 Standout
PRIM: Proximity imaging of green fluorescent protein-tagged polypeptides
1998 StandoutNobel
Controlling Signal Transduction with Synthetic Ligands
1993 Science
Conformation of FK506 in X-ray structures of its complexes with human recombinant FKBP12 mutants
1995
Signal Transduction through MAP Kinase Cascades
1998 Standout
Caspases: Enemies Within
1998 StandoutScience
Yeast as model T cells
1994
Works of Dan Yang being referenced
A composite FKBP12-FK506 surface that contacts calcineurin
1993