Citation Impact
Citing Papers
Cdc42 acts downstream of Bazooka to regulate neuroblast polarity through Par-6–aPKC
2007
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
A polybasic domain in aPKC mediates Par6-dependent control of membrane targeting and kinase activity
2020
Functional specialization of β-arrestin interactions revealed by proteomic analysis
2007 StandoutNobel
Defining the Epithelial Stem Cell Niche in Skin
2003 StandoutScience
C. elegans PAR-3 and PAR-6 are required for apicobasal asymmetries associated with cell adhesion and gastrulation
2003
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
2015 StandoutScienceNobel
Regulation of the Polarity Protein Par6 by TGFß Receptors Controls Epithelial Cell Plasticity
2005 Science
Suppression of Hypoxia-Inducible Factor 2α Restores p53 Activity via Hdm2 and Reverses Chemoresistance of Renal Carcinoma Cells
2009
Par complex cluster formation mediated by phase separation
2020
aPKC Phosphorylation of Bazooka Defines the Apical/Lateral Border in Drosophila Epithelial Cells
2010
On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
2016 StandoutNatureNobel
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
EphrinB Phosphorylation and Reverse Signaling
2002
Cortical Flows Powered by Asymmetrical Contraction Transport PAR Proteins to Establish and Maintain Anterior-Posterior Polarity in the Early C. elegans Embryo
2004
Intercellular junctions and cellular polarity: the PAR–aPKC complex, a conserved core cassette playing fundamental roles in cell polarity
2001
Asymmetric cell division during animal development
2001
Cell biological regulation of division fate in vertebrate neuroepithelial cells
2011
Interaction Codes within the Family of Mammalian Phox and Bem1p Domain-containing Proteins
2003
Oncogenic kinase signalling
2001 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Assembly of Epithelial Tight Junctions Is Negatively Regulated by Par6
2002
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Hippocampal Neuronal Polarity Specified by Spatially Localized mPar3/mPar6 and PI 3-Kinase Activity
2003
Autocrine VEGF Signaling Is Required for Vascular Homeostasis
2007
Spindle orientation in mammalian cerebral cortical development
2012
Multifunctional strands in tight junctions
2001 Standout
CDC-42 regulates PAR protein localization and function to control cellular and embryonic polarity in C. elegans
2001
Apical–basal polarity and the control of epithelial form and function
2022
PAR‐6 regulates aPKC activity in a novel way and mediates cell‐cell contact‐induced formation of the epithelial junctional complex
2001
Self-association of PAR-3-mediated by the Conserved N-terminal Domain Contributes to the Development of Epithelial Tight Junctions
2003
The cell-polarity protein Par6 links Par3 and atypical protein kinase C to Cdc42
2000
Eph receptors and ephrin ligands: embryogenesis to tumorigenesis
2000
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Lymphangiogenesis in development and human disease
2005 StandoutNature
Asymmetric cell division during neurogenesis in Drosophila and vertebrates
2003
AKAP-Lbc Anchors Protein Kinase A and Nucleates Gα12-selective Rho-mediated Stress Fiber Formation
2001
Rho GTPases in cell biology
2002 StandoutNature
Eph signaling: a structural view
2002
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis
2010 Nature
Structure of a Cell Polarity Regulator, a Complex between Atypical PKC and Par6 PB1 Domains
2004
Cortical progenitor expansion, self-renewal and neurogenesis—a polarized perspective
2010
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
The cell biology of neurogenesis
2005 Standout
The von Hippel-Lindau Tumor Suppressor Protein Mediates Ubiquitination of Activated Atypical Protein Kinase C
2001
Role of Rho family GTPases in epithelial morphogenesis
2002
VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis
2010
Proteomic, Functional, and Domain-Based Analysis of In Vivo 14-3-3 Binding Proteins Involved in Cytoskeletal Regulation and Cellular Organization
2004
CDC-42 controls early cell polarity and spindle orientation in C. elegans
2001
Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization
2008
The immune response of Drosophila
2003 StandoutNatureNobel
Phase transitions in the assembly of multivalent signalling proteins
2012 StandoutNature
Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer
2009
Structural organization of the tight junctions
2007
Association of ASIP/mPAR‐3 with adherens junctions of mouse neuroepithelial cells
2002
Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells
2004
Mechanisms and functions of eph and ephrin signalling
2002 Standout
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
aPKC Inhibition by Par3 CR3 Flanking Regions Controls Substrate Access and Underpins Apical-Junctional Polarization
2016
Eph receptors and ephrins: Regulators of guidance and assembly
2000
Mitotic Spindle Orientation in Asymmetric and Symmetric Cell Divisions during Animal Development
2011
Hypoxic gene expression and metastasis
2004
Ephrin-B Reverse Signaling Is Mediated by a Novel PDZ-RGS Protein and Selectively Inhibits G Protein–Coupled Chemoattraction
2001
Vascular-specific growth factors and blood vessel formation
2000 StandoutNature
Crystal structure of an Eph receptor–ephrin complex
2001 Nature
Cellular and Molecular Mechanisms of Vascular Lumen Formation
2009
Eph Receptors and Ephrin Ligands Essential Mediators of Vascular Development
2000
The GIT Family of Proteins Forms Multimers and Associates with the Presynaptic Cytomatrix Protein Piccolo
2003
Asymmetric cell division in the Drosophila nrevous system
2001
Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, Angiopoietins, and ephrins in vascular development
1999
Neuronal polarity: from extracellular signals to intracellular mechanisms
2007
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
2003 StandoutNature
The Par3/Par6/aPKC complex and epithelial cell polarity
2013
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
A Conserved Oligomerization Domain in Drosophila Bazooka/PAR-3 Is Important for Apical Localization and Epithelial Polarity
2003
Cell polarity: Par6, aPKC and cytoskeletal crosstalk
2003
Integrin-Mediated Activation of Cdc42 Controls Cell Polarity in Migrating Astrocytes through PKCζ
2001
Seven-transmembrane receptors
2002 StandoutNobel
A Conserved PDZ-Binding Motif in aPKC Interacts with Par-3 and Mediates Cortical Polarity
2020
Multiple roles of eph receptors and ephrins in neural development
2001
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Kinase-Dependent and Kinase-Independent Functions of EphA4 Receptors in Major Axon Tract Formation In Vivo
2001
NF-κB at the crossroads of life and death
2002 Standout
The Human Condition—A Molecular Approach
2014 StandoutNobel
In Vivo Tyrosine Phosphorylation Sites of Activated Ephrin-B1 and EphB2 from Neural Tissue
2001
Mechanisms that regulate the number of neurons during mouse neocortical development
2010
Epidermolysis bullosa and embryonic lethality in mice lacking the multi-PDZ domain protein GRIP1
2002
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
Protein–protein interactions define specificity in signal transduction
2000
Life with Oxygen
2007 StandoutScienceNobel
Cell Migration: Integrating Signals from Front to Back
2003 StandoutScience
Axonal Ephrin-As and Odorant Receptors
2003 StandoutNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
The Drosophila Atypical Protein Kinase C-Ref(2)P Complex Constitutes a Conserved Module for Signaling in the Toll Pathway
2002
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
A family of RIM-binding proteins regulated by alternative splicing: Implications for the genesis of synaptic active zones
2002 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
The extracellular matrix geneFrem1is essential for the normal adhesion of the embryonic epidermis
2004 StandoutNobel
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Fibroblast Growth Factor Receptor-Mediated Rescue of x-Ephrin B1-Induced Cell Dissociation in XenopusEmbryos
2000
Assembly of Cell Regulatory Systems Through Protein Interaction Domains
2003 Science
Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells
2006 StandoutNobel
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Mechanism and role of PDZ domains in signaling complex assembly
2001
Establishment of Axon-Dendrite Polarity in Developing Neurons
2009
The Partner of Inscuteable/Discs-Large Complex Is Required to Establish Planar Polarity during Asymmetric Cell Division in Drosophila
2001
RHO GTPASES: Biochemistry and Biology
2005 Standout
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
2013 StandoutScienceNobel
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
2012 StandoutNobel
Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis
2010 StandoutNobel
The cell polarity protein ASIP/PAR-3 directly associates with junctional adhesion molecule (JAM)
2001
EphB2 Guides Axons at the Midline and Is Necessary for Normal Vestibular Function
2000
De novo design of protein logic gates
2020 StandoutScienceNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Nucleotide Exchange Factor ECT2 Interacts with the Polarity Protein Complex Par6/Par3/Protein Kinase Cζ (PKCζ) and Regulates PKCζ Activity
2004
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
Works of Dan Lin being referenced
A mammalian PAR-3–PAR-6 complex implicated in Cdc42/Rac1 and aPKC signalling and cell polarity
2000
Mdm2-mediated NEDD8 Modification of TAp73 Regulates Its Transactivation Function
2006
Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells
2009
The Carboxyl Terminus of B Class Ephrins Constitutes a PDZ Domain Binding Motif
1999
APPL1 Associates with TrkA and GIPC1 and Is Required for Nerve Growth Factor-Mediated Signal Transduction
2006