Citation Impact
Citing Papers
Recommendations from the EGAPP Working Group: genetic testing strategies in newly diagnosed individuals with colorectal cancer aimed at reducing morbidity and mortality from Lynch syndrome in relatives
2009
Epigenetic Repression of DNA Mismatch Repair by Inflammation and Hypoxia in Inflammatory Bowel Disease–Associated Colorectal Cancer
2009 StandoutNobel
The Search for Unaffected Individuals with Lynch Syndrome: Do the Ends Justify the Means?
2011
GEPIA2: an enhanced web server for large-scale expression profiling and interactive analysis
2019 Standout
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Loss of the Mismatch Repair Protein MSH6 in Human Glioblastomas Is Associated with Tumor Progression during Temozolomide Treatment
2007
2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer
2015 Standout
Cancer immunotherapies targeting the PD-1 signaling pathway
2017 StandoutNobel
Immunohistochemistry versus Microsatellite Instability Testing For Screening Colorectal Cancer Patients at Risk For Hereditary Nonpolyposis Colorectal Cancer Syndrome
2008
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2024 Standout
New Developments in Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer) and Mismatch Repair Gene Testing
2006
Molecular Subtypes of Colorectal Cancer and Their Clinicopathologic Features, With an Emphasis on the Serrated Neoplasia Pathway
2016
Immunohistochemistry as First-line Screening for Detecting Colorectal Cancer Patients at Risk for Hereditary Nonpolyposis Colorectal Cancer Syndrome
2009
Microsatellite instability in colorectal cancer—the stable evidence
2010
Correlation of tumour BRAF mutations and MLH1 methylation with germline mismatch repair (MMR) gene mutation status: a literature review assessing utility of tumour features for MMR variant classification
2012
Base-excision repair of oxidative DNA damage
2007 StandoutNature
Phenotypic and genotypic heterogeneity in the Lynch syndrome: diagnostic, surveillance and management implications
2006
Frequency of Hereditary Non-Polyposis Colorectal Cancer among Unselected Patients with Colorectal Cancer in Germany
2006
Cost-effectiveness of surveillance programs for families at high and moderate risk of hereditary non-polyposis colorectal cancer
2007
Microsatellite Instability in Colorectal Cancer
2010 Standout
European evidence based consensus for endoscopy in inflammatory bowel disease
2013 Standout
Ovarian cancer
2014 Standout
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
Molecular Basis of Colorectal Cancer
2009
The efficacy of adjuvant chemotherapy with 5-fluorouracil in colorectal cancer depends on the mismatch repair status
2008
Cushing's syndrome
2015 Standout
Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002)
2010
Global burden of colorectal cancer: emerging trends, risk factors and prevention strategies
2019 Standout
Familial Colon Cancer Syndromes: an Update of a Rapidly Evolving Field
2012
Hereditary ovarian carcinoma: Heterogeneity, molecular genetics, pathology, and management
2009
The immune contexture in cancer prognosis and treatment
2017 Standout
Microsatellite instability: an update
2015
Colorectal cancer
2013 Standout
Lynch Syndrome Patients with Limited Family History Identified in a Laboratory Setting: A Descriptive Study
2015 Standout
MutS switches between two fundamentally distinct clamps during mismatch repair
2011
EGAPP supplementary evidence review: DNA testing strategies aimed at reducing morbidity and mortality from Lynch syndrome
2009
Irritable bowel syndrome
2016 Standout
Colorectal cancer
2019 Standout
The Hippo Signaling Pathway in Development and Cancer
2010 Standout
Inflammation and Colon Cancer
2010 Standout
Ulcerative colitis
2012 Standout
Clinical Performance of Original and Revised Bethesda Guidelines for the Identification of MSH2/MLH1 Gene Carriers in Patients with Newly Diagnosed Colorectal Cancer: Proposal of a New and Simpler Set of Recommendations
2006
The Clinical Phenotype of Lynch Syndrome Due to Germ-Line PMS2 Mutations
2008
Relevance, Pathogenesis, and Testing Algorithm for Mismatch Repair–Defective Colorectal Carcinomas
2012
Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates
2009 Standout
Molecular models for the tissue specificity of DNA mismatch repair-deficient carcinogenesis
2006
Prediction of MLH1 and MSH2 Mutations in Lynch Syndrome
2006
Opportunities for immunotherapy in microsatellite instable colorectal cancer
2016
How were new medicines discovered?
2011 Standout
Lower Gastrointestinal Tract Cancer Predisposition Syndromes
2010
Milestones of Lynch syndrome: 1895–2015
2015
Underutilization of microsatellite instability analysis in colorectal cancer patients at high risk for Lynch syndrome
2009
Genetics, Inheritance and Strategies for Prevention in Populations at High Risk of Colorectal Cancer (CRC)
2012
Electronic reminders for pathologists promote recognition of patients at risk for Lynch syndrome: cluster-randomised controlled trial
2010
Differential Features of Colorectal Cancers Fulfilling Amsterdam Criteria without Involvement of the Mutator Pathway
2005
Review article: the Lynch syndrome (hereditary nonpolyposis colorectal cancer)*
2007
Cisplatin: The first metal based anticancer drug
2019 Standout
Hereditary and Familial Colon Cancer
2010
Cisplatin in cancer therapy: Molecular mechanisms of action
2014 Standout
Report From the Jerusalem Workshop on Lynch Syndrome-Hereditary Nonpolyposis Colorectal Cancer
2010
Identification and Survival of Carriers of Mutations in DNA Mismatch-Repair Genes in Colon Cancer
2006
Clinical and molecular features of young-onset colorectal cancer
2016
Prognostic significance of mammalian sterile20-like kinase 1 in colorectal cancer
2007
Cancer as an evolutionary and ecological process
2006 Standout
Most Patients with Colorectal Tumors at Young Age Do Not Visit a Cancer Genetics Clinic
2008
Review of the Lynch syndrome: history, molecular genetics, screening, differential diagnosis, and medicolegal ramifications
2009
Tumour heterogeneity and resistance to cancer therapies
2017 Standout
Histologic features distinguish microsatellite-high from microsatellite-low and microsatellite-stable colorectal carcinomas, but do not differentiate germline mutations from methylation of the MLH1 promoter
2006
TGF-β signaling alterations and susceptibility to colorectal cancer
2007
Young-onset colorectal cancer
2023
ACG Clinical Guideline: Genetic Testing and Management of Hereditary Gastrointestinal Cancer Syndromes
2015
Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors
2019 Standout
The cancer genome
2009 StandoutNature
Yield of routine molecular analyses in colorectal cancer patients ≤70 years to detect underlying Lynch syndrome
2011
A Prospective, Multicenter, Population-Based Study of BRAF Mutational Analysis for Lynch Syndrome Screening
2007
Molecular Testing in Colorectal Cancer
2012
Audit and feedback: effects on professional practice and healthcare outcomes
2012 Standout
Mismatch Repair Deficiency Does Not Mediate Clinical Resistance to Temozolomide in Malignant Glioma
2008 StandoutNobel
Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD): Explanation and Elaboration
2015 Standout
Hereditary gynaecological malignancies: advances in screening and treatment
2012
Clinical Relevance of Microsatellite Instability in Colorectal Cancer
2010
NCCN Task Force Report: Evaluating the Clinical Utility of Tumor Markers in Oncology
2011
Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer
2012
Practical genetics of colorectal cancer.
2013
Identification of Individuals at Risk for Lynch Syndrome Using Targeted Evaluations and Genetic Testing: National Society of Genetic Counselors and the Collaborative Group of the Americas on Inherited Colorectal Cancer Joint Practice Guideline
2011
Microsatellite instability in colorectal cancer
2006
Transcript Profiling and RNA Interference as Tools To Identify Small Molecule Mechanisms and Therapeutic Potential
2010
Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade
2016
Adrenocortical Carcinoma
2013
Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors
2016 Standout
Microsatellite Instability as a Biomarker for PD-1 Blockade
2016
Colorectal carcinoma: Pathologic aspects.
2012
Works of Dan Fix being referenced
Origins and Prevalence of the American Founder Mutation of MSH2
2008
Screening for the Lynch Syndrome (Hereditary Nonpolyposis Colorectal Cancer)
2005
Feasibility of Screening for Lynch Syndrome Among Patients With Colorectal Cancer
2008