Citation Impact
Citing Papers
ZBTB1 is a determinant of lymphoid development
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Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL
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CTLA-4-Mediated Inhibition of Early Events of T Cell Proliferation
1999 StandoutNobel
A pupal transcriptomic screen identifies Ral as a target of store-operated calcium entry in Drosophila neurons
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Correlation of Transcriptional Repression by p21SNFTwith Changes in DNA·NF-AT Complex Interactions
2002
Calcineurin Binds the Transcription Factor NFAT1 and Reversibly Regulates Its Activity
1996
Combinatorial gene regulation by eukaryotic transcription factors
1999
Higher-order nucleoprotein complexes in transcription: analogies with site-specific recombination
1995
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
2006 StandoutNature
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Cells’ Perception of Position in a Concentration Gradient
1998 StandoutNobel
Regulation of αβ/γδ T Cell Lineage Commitment and Peripheral T Cell Responses by Notch/RBP-J Signaling
2004 StandoutNobel
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
A Novel Transcription Factor, T-bet, Directs Th1 Lineage Commitment
2000 Standout
Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA
1998 Nature
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Transcriptional regulation by calcium, calcineurin, and NFAT
2003 Standout
T cell clonal anergy
1997
An oligopeptide ligand-mediated therapeutic gene nanocomplex for liver cancer-targeted therapy
2011
Hematopoiesis: An Evolving Paradigm for Stem Cell Biology
2008 Standout
The Development of Functionally Responsive T Cells
1992
Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway
1999 StandoutNobel
Single-Molecule Dynamics of Enhanceosome Assembly in Embryonic Stem Cells
2014 StandoutNobel
Regulation of lymphocyte development by Notch signaling
2007 StandoutNobel
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
2010 Standout
Modeling the dynamics of transcriptional gene regulatory networks for animal development
2008
The Mammalian Epigenome
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A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 StandoutNature
The DNA Damage Response: Making It Safe to Play with Knives
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The Roles of Nuclear Factor of Activated T Cells and Ying-Yang 1 in Activation-induced Expression of the Interferon-γ Promoter in T Cells
1998
B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion
1999 Standout
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
2010 Standout
The architecture of the interleukin-2 promoter: a reflection of T lymphocyte activation
1995
NF-κB regulation in the immune system
2002 Standout
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process
2003
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
1997 Standout
Genomic instability and the selection of treatments for cancer
2009
T cell receptor antagonist peptides induce positive selection
1994 Standout
Regulatory coding of lymphoid lineage choice by hematopoietic transcription factors
2003
Delayed, asynchronous, and reversible T-lineage specification induced by Notch/Delta signaling
2005
Mast cell lineage diversion of T lineage precursors by the essential T cell transcription factor GATA-3
2007
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
2010 StandoutNature
Transcriptional regulation of the IL-2 gene
1995
DNA structure in human RNA polymerase II promoters 1 1Edited by J. Karn
1998 StandoutNobel
Global quantification of mammalian gene expression control
2011 StandoutNature
The Transcription Factor GATA-3 Is Necessary and Sufficient for Th2 Cytokine Gene Expression in CD4 T Cells
1997 Standout
A Calcineurin-Dependent Transcriptional Pathway for Cardiac Hypertrophy
1998 Standout
bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
1993 Standout
The Overexpression of Bax Produces Cell Death upon Induction of the Mitochondrial Permeability Transition
1998 Standout
Scurfin (FOXP3) Acts as a Repressor of Transcription and Regulates T Cell Activation
2001 StandoutNobel
Immunosuppressive and Anti-Inflammatory Mechanisms of Triptolide, the Principal Active Diterpenoid from the Chinese Medicinal Herb Tripterygium wilfordii Hook. f.
2003
RORγt, a Novel Isoform of an Orphan Receptor, Negatively Regulates Fas Ligand Expression and IL-2 Production in T Cells
1998
Distinct transcriptional programs in thymocytes responding to T cell receptor, Notch, and positive selection signals
2004
NFATx, a Novel Member of the Nuclear Factor of Activated T Cells Family That Is Expressed Predominantly in the Thymus
1995
Interleukin-7 Upregulates the Interleukin-2–Gene Expression in Activated Human T Lymphocytes at the Transcriptional Level by Enhancing the DNA Binding Activities of Both Nuclear Factor of Activated T Cells and Activator Protein-1
1997
Transcription Mediated by NFAT Is Highly Inducible in Effector CD4+ T Helper 2 (Th2) Cells but Not in Th1 Cells
1997
Single Cell Analysis Reveals Regulated Hierarchical T Cell Antigen Receptor Signaling Thresholds and Intraclonal Heterogeneity for Individual Cytokine Responses of CD4+ T Cells
1997
Novel NFAT Sites That Mediate Activation of the Interleukin-2 Promoter in Response to T-Cell Receptor Stimulation
1995
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
AP-1 transcriptional activity requires both T-cell receptor-mediated and co-stimulatory signals in primary T lymphocytes.
1994
IL-17 and Th17 Cells
2009 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Gene Regulation: Gene Control Network in Development
2007
Varicella-zoster virus
1996 Standout
Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors.
1994
An Essential Role for Nuclear Factor κB in Promoting Double Positive Thymocyte Apoptosis
1999
How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions*
2000 Standout
Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells.
1995
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
NF-κB AND REL PROTEINS: Evolutionarily Conserved Mediators of Immune Responses
1998 Standout
TRANSCRIPTION FACTORS OF THE NFAT FAMILY:Regulation and Function
1997 Standout
Transcriptional Activation of the Interleukin-2 Promoter by Hepatitis C Virus Core Protein
2001 StandoutNobel
High-Level Replication of Human Immunodeficiency Virus in Thymocytes Requires NF-κB Activation through Interaction with Thymic Epithelial Cells
1999 StandoutNobel
Interleukin 2 transcription factors as molecular targets of cAMP inhibition: delayed inhibition kinetics and combinatorial transcription roles.
1994
Altered peptidase and viral-specific T cell response in LMP2 mutant mice
1994 StandoutNobel
Perturbation of the T Lymphocyte Lineage In Transgenic Mice Expressing a Constitutive Repressor of Nuclear Factor (NF)-κB
1997
THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
1996 Standout
Identification of a Novel Developmental Stage Marking Lineage Commitment of Progenitor Thymocytes
1997
MOLECULAR GENETICS OF T CELL DEVELOPMENT
2004
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Glucocorticoid receptor-mediated suppression of the interleukin 2 gene expression through impairment of the cooperativity between nuclear factor of activated T cells and AP-1 enhancer elements.
1992
Molecular Mechanisms of Mammalian DNA Repair and the DNA Damage Checkpoints
2004 StandoutNobel
Works of Dan Chen being referenced
The Varicella-Zoster virus origin-binding protein can substitute for the herpes simplex virus origin-binding protein in a transient origin-dependent DNA replication assay in insect cells
1995
ERCC6/CSB gene polymorphisms and lung cancer risk
2008
Acquisition of Mature Functional Responsiveness in T Cells: Programming for Function via Signaling
1991
Definition of Regulatory Network Elements for T Cell Development by Perturbation Analysis with PU.1 and GATA-3
2002
Interleukin-1 Synergy with Phosphoinositide Pathway Agonists for Induction of Interleukin-2 Gene Expression: Molecular Basis of Costimulation
1990
Molecular Basis for Developmental Changes in Interleukin-2 Gene Inducibility
1993
Polyethyleneimine-grafted poly(N-3-hydroxypropyl)aspartamide as a biodegradable gene vector for efficient gene transfection
2010
Interleukin-2 Transcription Is Regulated In Vivo at the Level of Coordinated Binding of Both Constitutive and Regulated Factors
1994