Citation Impact
Citing Papers
Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes
2010 Science
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX–DNMT3–DNMT3L domain
2009
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
Direct and Catalytic C ‐Glycosylation of Arenes: Expeditious Synthesis of the Remdesivir Nucleoside**
2021 StandoutNobel
Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins
2019
Repression of hypoxia-inducible factor α signaling by Set7-mediated methylation
2015
Epigenetic mechanisms in mammals
2008
Dynamic instability of genomic methylation patterns in pluripotent stem cells
2010
Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L
2007
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Engineering synthetic biomolecular condensates
2023
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 StandoutNature
Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger
2009 Nature
Signals and Combinatorial Functions of Histone Modifications
2011
Establishing, maintaining and modifying DNA methylation patterns in plants and animals
2010 Standout
The molecular hallmarks of epigenetic control
2016 Standout
Histone Methyl Transferases and Demethylases; Can They Link Metabolism and Transcription?
2010
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
2011 Nature
Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation
2012
CpG islands and the regulation of transcription
2011 Standout
Genome-wide analysis of 5-hydroxymethylcytosine distribution reveals its dual function in transcriptional regulation in mouse embryonic stem cells
2011
The Dnmt3a PWWP Domain Reads Histone 3 Lysine 36 Trimethylation and Guides DNA Methylation
2010
Epigenetic regulation: methylation of histone and non-histone proteins
2009
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail
2010
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Epigenetic events in mammalian germ-cell development: reprogramming and beyond
2008
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
2011 StandoutNature
R-Loop Formation Is a Distinctive Characteristic of Unmethylated Human CpG Island Promoters
2012
Structural Insight Into Histone Recognition by the ING PHD Fingers
2009
Targeting Epigenetic Readers in Cancer
2012
DNA Methylation and SETDB1/H3K9me3 Regulate Predominantly Distinct Sets of Genes, Retroelements, and Chimeric Transcripts in mESCs
2011
Regulation of chromatin by histone modifications
2011 Standout
Structural Basis for Cooperative Function of Mettl3 and Mettl14 Methyltransferases
2016
Developmental programming of CpG island methylation profiles in the human genome
2009
Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development
2008
Global Mapping of DNA Methylation in Mouse Promoters Reveals Epigenetic Reprogramming of Pluripotency Genes
2008
A Maternal-Zygotic Effect Gene, Zfp57, Maintains Both Maternal and Paternal Imprints
2008
How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers
2007
Array-based genomic resequencing of human leukemia
2010
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Genetic evidence for Dnmt3a‐dependent imprinting during oocyte growth obtained by conditional knockout with Zp3‐Cre and complete exclusion of Dnmt3b by chimera formation
2010
A Structural Perspective on Readout of Epigenetic Histone and DNA Methylation Marks
2016
A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice
2008
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
2008 StandoutNature
Mammalian DNA Methyltransferases: A Structural Perspective
2008
Dynamic CpG island methylation landscape in oocytes and preimplantation embryos
2011
H3K9 methyltransferase G9a and the related molecule GLP
2011
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing
2009
Nucleosomes Containing Methylated DNA Stabilize DNA Methyltransferases 3A/3B and Ensure Faithful Epigenetic Inheritance
2011
Chromatin mechanisms in genomic imprinting
2009
DNA methylation: roles in mammalian development
2013 Standout
The Inherent Processivity of the Human de Novo Methyltransferase 3A (DNMT3A) Is Enhanced by DNMT3L
2010
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids
2009
Mechanism and regulation of acetylated histone binding by the tandem PHD finger of DPF3b
2010 Nature
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Hydroxylation mediates chromatin demethylation
2012
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Gestational Choline Deficiency Causes Global and Igf2 Gene DNA Hypermethylation by Up-regulation of Dnmt1 Expression
2007
The Histone Chaperone Spt6 Is Required for Activation-induced Cytidine Deaminase Target Determination through H3K4me3 Regulation
2012 StandoutNobel
Regulation and function of DNA methylation in plants and animals
2011
KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints
2009 Nature
Histone tails regulate DNA methylation by allosterically activating de novo methyltransferase
2011
Relationship between nucleosome positioning and DNA methylation
2010 Nature
DNA Methylation and Its Basic Function
2012 Standout
Phase transitions in the assembly of multivalent signalling proteins
2012 StandoutNature
The SET-domain protein superfamily: protein lysine methyltransferases.
2005
DNA Methylation in Mammals
2014
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome
2012
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
EMT: 2016
2016 Standout
De novo DNA methylation promoted by G9a prevents reprogramming of embryonically silenced genes
2008
ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs
2011
Driver mutations of cancer epigenomes
2014
Histone Modifications and Cancer
2016
Structural and Functional Coordination of DNA and Histone Methylation
2014
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
Genome-wide analysis of mono-, di- and trimethylation of histone H3 lysine 4 in Arabidopsis thaliana
2009
Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a
2008
Modification of Enhancer Chromatin: What, How, and Why?
2013
Smchd1-Dependent and -Independent Pathways Determine Developmental Dynamics of CpG Island Methylation on the Inactive X Chromosome
2012
Charting histone modifications and the functional organization of mammalian genomes
2010
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout
Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals
2009
CG dinucleotide periodicities recognized by the Dnmt3a–Dnmt3L complex are distinctive at retroelements and imprinted domains
2009
Removal of deaminated cytosines and detection of in vivo methylation in ancient DNA
2009 StandoutNobel
The DNA methylome
2010
Rethinking how DNA methylation patterns are maintained
2009
ICF Syndrome Mutations Cause a Broad Spectrum of Biochemical Defects in DNMT3B-Mediated De Novo DNA Methylation
2011
CpG islands influence chromatin structure via the CpG-binding protein Cfp1
2010 Nature
Epigenetic modifications and human disease
2010 Standout
Genetics and epigenetics: stability and plasticity during cellular differentiation
2009
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
2010 StandoutNature
A decade of exploring the cancer epigenome — biological and translational implications
2011 Standout
Epigenetic modifications in pluripotent and differentiated cells
2010
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Cfp1 integrates both CpG content and gene activity for accurate H3K4me3 deposition in embryonic stem cells
2012
The epigenetics of aging and neurodegeneration
2015
Multivalent engagement of chromatin modifications by linked binding modules
2007
Transcription is required for establishment of germline methylation marks at imprinted genes
2009
Topological domains in mammalian genomes identified by analysis of chromatin interactions
2012 StandoutNature
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
De novo DNA methylation: a germ cell perspective
2011
Dynamic protein methylation in chromatin biology
2008
The H19 locus: Role of an imprinted non‐coding RNA in growth and development
2010
Linking DNA methylation and histone modification: patterns and paradigms
2009 Standout
The Polycomb complex PRC2 and its mark in life
2011 StandoutNature
A Novel CpG Island Set Identifies Tissue-Specific Methylation at Developmental Gene Loci
2008
Epigenetic Regulation of EMT: The Snail Story
2014
Chromatin remodeling and cancer, part II: ATP-dependent chromatin remodeling
2007
CpG islands – ‘A rough guide’
2009
Protein methyltransferases as a target class for drug discovery
2009
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
DNA methylation: TET proteins—guardians of CpG islands?
2011
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Structural and Sequence Motifs of Protein (Histone) Methylation Enzymes
2005
Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells
2012 StandoutNobel
Acute Myeloid Leukemia
2015 Standout
Locus-Specific Control of DNA Methylation by theArabidopsisSUVH5 Histone Methyltransferase
2006
OCT4 establishes and maintains nucleosome-depleted regions that provide additional layers of epigenetic regulation of its target genes
2011
Phase transitions of multivalent proteins can promote clustering of membrane receptors
2014
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Reconstructing the DNA Methylation Maps of the Neandertal and the Denisovan
2014 StandoutScienceNobel
Structure and function of histone methylation binding proteinsThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.
2009
DOT1L/KMT4 Recruitment and H3K79 Methylation Are Ubiquitously Coupled with Gene Transcription in Mammalian Cells
2008
Site-Selective Functionalization of Hydroxyl Groups in Carbohydrate Derivatives
2018
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Structural Insight into the Recognition of the H3K4me3 Mark by the TFIID Subunit TAF3
2008
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
2010
Cancer Genome Landscapes
2013 StandoutScience
The melanoma-associated antigen 1 (MAGEA1) protein stimulates the E3 ubiquitin-ligase activity of TRIM31 within a TRIM31-MAGEA1-NSE4 complex
2015
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Selective Anchoring of DNA Methyltransferases 3A and 3B to Nucleosomes Containing Methylated DNA
2009
Genes associated with Parkinson's disease: regulation of autophagy and beyond
2015
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
2010
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Epigenetic Reprogramming in Plant and Animal Development
2010 Science
Works of Da Jia being referenced
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
2007 Nature
Structural and mechanistic insights into regulation of the retromer coat by TBC1d5
2016
Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation
2014
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
2007 Nature
Regulation of Estrogen Receptor α by the SET7 Lysine Methyltransferase
2008
Formation of nucleoprotein filaments by mammalian DNA methyltransferase Dnmt3a in complex with regulator Dnmt3L
2008
Regulation of WASH-Dependent Actin Polymerization and Protein Trafficking by Ubiquitination
2013
In Vitro and in Vivo Analyses of a Phe/Tyr Switch Controlling Product Specificity of Histone Lysine Methyltransferases
2004
Molecular determinants for regulation of G3BP1/2 phase separation by the SARS-CoV-2 nucleocapsid protein
2021
WASH and WAVE actin regulators of the Wiskott–Aldrich syndrome protein (WASP) family are controlled by analogous structurally related complexes
2010
Site-Divergent Delivery of Terminal Propargyls to Carbohydrates by Synergistic Catalysis
2017
Multiple repeat elements within the FAM21 tail link the WASH actin regulatory complex to the retromer
2012