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Citing Papers
High-Resolution Crystal Structure of an Engineered Human β 2 -Adrenergic G Protein–Coupled Receptor
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The 2.6 Angstrom Crystal Structure of a Human A 2A Adenosine Receptor Bound to an Antagonist
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Identification of an adenosine receptor domain specifically involved in binding of 5'-substituted adenosine agonists.
1994
Budesonide/formoterol and formoterol provide similar rapid relief in patients with acute asthma showing refractoriness to salbutamol
2006
A binding site model and structure-activity relationships for the rat A3 adenosine receptor.
1994
Effect of adenosine receptor modulation on pentylenetetrazole‐induced seizures in rats
1997
Characterization of vascular P2 purinoceptors in the rat isolated perfused kidney
1996
lincRNAs: Genomics, Evolution, and Mechanisms
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Platelet-activating factor (PAF) receptor in rat brain: PAF mobilizes intracellular Ca2+ in hippocampal neurons
1992
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
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1,3-dialkylxanthine derivatives having high potency as antagonists at human A2B adenosine receptors
1999
MALAT-1, a novel noncoding RNA, and thymosin β4 predict metastasis and survival in early-stage non-small cell lung cancer
2003 Standout
Characterization of the adenosine receptor modulating insulin action in rat skeletal muscle
1992
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
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Evidence for co-expression and desensitization of A2a and A2b adenosine receptors in NG108-15 cells
1998
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2009 Standout
ERS/ESTS clinical guidelines on fitness for radical therapy in lung cancer patients (surgery and chemo-radiotherapy)
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Effect of adenosine and adenosine analogues on cyclic AMP accumulation in cultured mesangial cells and isolated glomeruli of the rat
1992
Functional characterization of the adenosine receptor mediating inhibition of peristalsis in the rat jejunum
1995
Adenosine A2a receptors in the nucleus accumbens mediate locomotor depression
1993
5-HT modulates protein synthesis and the expression of specific proteins during long-term facilitation in aplysia sensory neurons
1989 StandoutNobel
Palliative radiotherapy regimens for non-small cell lung cancer
2001
2-Chloro-N6-cyclopentyladenosine: a highly selective agonist at A1 adenosine receptors
1988
Cultured vascular smooth muscle cells from porcine coronary artery possess A1 and A2 adenosine receptor activity
1990
Randomized phase III trial of single versus fractionated thoracic radiation in the palliation of patients with lung cancer (NCIC CTG SC.15)
2002
A novel non-xanthine adenosine A1 receptor antagonist
1995
Pulmonary immune cells in health and disease: the eosinophil leucocyte (Part II)
1994
Gold Nanocages: A Novel Class of Multifunctional Nanomaterials for Theranostic Applications
2010
Agonist activity of 2- and 5′-substituted adenosine analogs and their N6-cycloalkyl derivatives at A1− and A2−adenosine receptors coupled to adenylate cyclase
1992
Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
2009 Standout
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Extracellular 2‐chloroadenosine and ATP stimulate volume‐sensitive Cl− current and calcium mobilization in human tracheal 9HTEo− cells
1992
Characterization of the adenosine receptor in microvascular coronary endothelial cells
1994
Cloning and expression of a bovine adenosine A1 receptor cDNA
1992
Caffeine antinociception: role of formalin concentration and adenosine A1 and A2 receptors
1996
Effect of Pertussis Toxin on Radioligand Binding to Rat Brain Adenosine A1 Receptors
1992
A comparison of A2 adenosine receptor‐induced cyclic AMP generation in cerebral cortex and relaxation of pre‐contracted aorta
1994
Primary Pulmonary Hypertension
1997 Standout
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update
2011 Standout
Comparison of A1 adenosine receptors in brain from different species by radioligand binding and photoaffinity labelling
1991
Adenosine analogs with covalently attached lipids have enhanced potency at A1‐adenosine receptors
1987
Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblasts
1994
Identification of the Adenine Binding Site of the Human A1 Adenosine Receptor
1999
New structural motif for ligand-gated ion channels defined by an ionotropic ATP receptor
1994 StandoutNatureNobel
Erlotinib in Previously Treated Non–Small-Cell Lung Cancer
2005 Standout
Synthesis of Prussian Blue Nanoparticles with a Hollow Interior by Controlled Chemical Etching
2011 StandoutNobel
Species differences in brain adenosine A1 receptor pharmacology revealed by use of xanthine and pyrazolopyridine based antagonists
1997
Phosphorylated CREB binds specifically to the nuclear protein CBP
1993 StandoutNature
Species differences in ligand affinity at central A3‐adenosine receptors
1994
Characterization of Membrane‐Bound and Solubilized High‐Affinity Binding Sites for 5′‐N‐Ethylcarboxamido[3H]adenosine from Bovine Cerebral Cortex
1993
Differential activation of adenosine receptors decreases N-type but potentiates P-type Ca2+ current in hippocampal CA3 neurons
1993
Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
2017 Standout
Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133
1989 Standout
Adenosine receptors mediate both contractile and relaxant effects of adenosine in main pulmonary artery of guinea pigs
1995
Budesonide/formoterol maintenance and reliever therapy: an effective asthma treatment option?
2005
Adenosine A2 receptor-mediated excitatory actions on the nervous system
1996
Effects of 5′-N-ethylcarboxamideadenosine (NECA) on erythropoietin production
1993
Effect of budesonide in combination with formoterol for reliever therapy in asthma exacerbations: a randomised controlled, double-blind study
2006
8‐(3‐Chlorostyryl)caffeine (CSC) is a selective A2‐adenosine antagonist in vitro and in vivo
1993
Binding of [3H]MSX-2 (3-(3-hydroxypropyl)-7-methyl-8-(m-methoxystyryl)-1-propargylxanthine) to rat striatal membranes — a new, selective antagonist radioligand for A2A adenosine receptors
2000
Vasodilatory effects of adenosine A2 receptor agonists CGS 21680 and CGS 22492 in human vasculature
1992
Positron emission tomography in the diagnosis and staging of lung cancer: a systematic, quantitative review
2001
In vivo pertussis toxin treatment attenuates some, but not all, adenosine A1 effects in slices of the rat hippocampus
1989
β-adrenoceptors on smooth muscle, nerves and inflammatory cells
1993
Randomized Controlled Trial of Resection Versus Radiotherapy After Induction Chemotherapy in Stage IIIA-N2 Non-Small-Cell Lung Cancer
2007
Effects of long-term theophylline treatment on adenosine A1-receptors in rat brain: autoradiographic evidence for increased receptor number and altered coupling to G-proteins
1990
Radiothérapie du cancer bronchique non à petites cellules de stade III, inopérable, asymptomatique. Résultats définitifs d'un essai prospectif randomisé (240 patients)
1999
Adenosine antagonists
1989
Global strategy for asthma management and prevention: GINA executive summary
2007 Standout
Separation of solubilized A2 adenosine receptors of human platelets from non-receptor [3H]NECA binding sites by gel filtration
1988
Memory of Extracellular Adenosine A2A Purinergic Receptor-mediated Signaling in Murine T Cells
1997 StandoutNobel
Modulation of calcium currents by a D1 dopaminergic protein kinase/phosphatase cascade in rat neostriatal neurons
1995 StandoutNobel
Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung
1991 Nature
Adenosine A1 and A2 receptors: Structure–function relationships
1992
High‐ and low‐affinity binding sites for [3H]‐α,β‐methylene ATP in rat urinary bladder membranes
1990
Factors associated with false-positive staging of lung cancer by positron emission tomography
2000
CT and 18F-deoxyglucose (FDG) image fusion for optimization of conformal radiotherapy of lung cancers
2001
Blocking Striatal Adenosine A2A Receptors: A New Strategy for Basal Ganglia Disorders
2007
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential
1992
Cloned adenosine A3 receptors: Pharmacological properties, species differences and receptor functions
1994
8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) ? a selective high affinity antagonist radioligand for A1 adenosine receptors
1987
Pharmacological strategies for self-management of asthma exacerbations: Table 1—
2006
Excitatory Amino Acids as a Final Common Pathway for Neurologic Disorders
1994 Standout
Characterization of the A2B Adenosine Receptor from Mouse, Rabbit, and Dog
2009
Magnesium‐Dependent Enhancement of Endogenous Agonist Binding to A1 Adenosine Receptors: A Complicating Factor in Quantitative Autoradiography
1992
Structure-Activity Relationships of N6-Benzyladenosine-5'-uronamides as A3-Selective Adenosine Agonists
1994
Physiological roles of A1and A2Aadenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine
2009
Beta2 adrenergic receptors in asthma: A current perspective
1992
Formation and inactivation of endogenous cannabinoid anandamide in central neurons
1994 StandoutNature
Recent developments in adenosine receptor ligands and their potential as novel drugs
2010
The in vitro pharmacology of ZM 241385, a potent, non‐xanthine, A2aselective adenosine receptor antagonist
1995
Identification of the platelet ADP receptor targeted by antithrombotic drugs
2001 StandoutNatureNobel
Identification of a novel high affinity adenosine binding protein from bovine striatum
1992
Overview: Purinergic Mechanisms
1990
Theophylline
2003
Oxidative Stress in Chronic Obstructive Pulmonary Disease
1997 Standout
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Adenosine receptor down-regulation and insulin resistance following prolonged incubation of adipocytes with an A1 adenosine receptor agonist.
1987
125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor.
1994
5‘-N-Substituted Carboxamidoadenosines as Agonists for Adenosine Receptors
1999
Expression cloning of an ATP receptor from mouse neuroblastoma cells.
1993 StandoutNobel
Receptors for Purines and Pyrimidines
1998 Standout
A1 adenosine receptors. Two amino acids are responsible for species differences in ligand recognition.
1994
Guidelines for management of asthma at primary and secondary levels of health care in India (2005).
2005
Synthesis and Evaluation of No-Carrier-Added 8-Cyclopentyl-3-(3-[18F]fluoropropyl)-1-propylxanthine ([18F]CPFPX): A Potent and Selective A1-Adenosine Receptor Antagonist for in Vivo Imaging
2002
Imidazo[2,1-i]purin-5-ones and Related Tricyclic Water-Soluble Purine Derivatives: Potent A2A- and A3-Adenosine Receptor Antagonists
2002
The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response
1988
Cholesterol increases kinetic, energetic, and mechanical stability of the human β2-adrenergic receptor
2012 StandoutNobel
Platelet-activating factor.
1990 Standout
Phorbol-12,13-dibutyrate enhances the cyclic AMP accumulation in rat hippocampal slices induced by adenosine analogues
1987
Gi down-regulation as a mechanism for heterologous desensitization in adipocytes.
1992
Structure−Activity Relationships at Human and Rat A2B Adenosine Receptors of Xanthine Derivatives Substituted at the 1-, 3-, 7-, and 8-Positions
2002
A3 Adenosine Receptor Ligands: History and Perspectives
2000
Purification and characterization of the adenosine A2-like binding site from human placental membrane
1989
Anilide Derivatives of an 8-Phenylxanthine Carboxylic Congener Are Highly Potent and Selective Antagonists at Human A2B Adenosine Receptors
2000
Chronic caffeine ingestion sensitizes the A1 adenosine receptor-adenylate cyclase system in rat cerebral cortex.
1986
cAMP response element-binding protein is activated by Ca2+/calmodulin- as well as cAMP-dependent protein kinase.
1991 StandoutNobel
Cardiac effects of adenosine in A2Areceptor knockout hearts: uncovering A2Breceptors
2002
Adenosine A1 receptors in mammalian brain: Species differences in their interactions with agonists and antagonists
1986
Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
2005 Standout
British Guideline on the Management of Asthma
2008
Carboplatin/Paclitaxel or Carboplatin/Vinorelbine Followed by Accelerated Hyperfractionated Conformal Radiation Therapy: A Preliminary Report of a Phase I Dose Escalation Trial from the Carolina Conformal Therapy Consortium
2001
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Adenosine receptors and calcium: Basis for proposing a third (A3) adenosine receptor
1986
Regulation of stably transfected platelet activating factor receptor in RBL-2H3 cells. Role of multiple G proteins and receptor phosphorylation.
1994
Pharmacological and immunohistochemical evidence for a functional nitric oxide synthase system in rat peritoneal eosinophils
1997 StandoutNobel
Identification of the A2 adenosine receptor binding subunit by photoaffinity crosslinking.
1989
Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements
1987 Standout
Identification and function of A1 adenosine receptors in normal and cystic fibrosis human airway epithelial cells
1995
A cyclic AMP- and phorbol ester-inducible DNA element
1986 Nature
Phosphodiesterase 4D is required for β 2 adrenoceptor subtype-specific signaling in cardiac myocytes
2005 StandoutNobel
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
Photoaffinity labeling of A1-adenosine receptors.
1985
Further characterization of the binding of the adenosine receptor agonist [3H]CGS 21680 to rat brain using autoradiography
1995
cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.
1989 StandoutNobel
Oscillating Crystallization of (+) and (–) Enantiomers during Resolution by Entrainment of 2‐Azabicyclo[2.2.1]hept‐5‐en‐3‐one
1996
Adenosine as a vasodilator in primary pulmonary hypertension.
1991
A1 adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins Gi1, Gi2, and Go.
1991
Progress and prospects of early detection in lung cancer
2017
G PROTEIN–COUPLED RECEPTOR KINASES
1998 StandoutNobel
ESTS guidelines for preoperative lymph node staging for non-small cell lung cancer
2007
A2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase.
1992
The potential for isoenzyme‐selective modulation of protein kinase C
1997
Activation of phospholipase C via adenosine receptors provides synergistic signals for secretion in antigen-stimulated RBL-2H3 cells. Evidence for a novel adenosine receptor.
1990
From Furan to Nucleosides
1996
Elucidation of structure-activity relationships of 2-amino-3-benzoylthiophenes: Study of their allosteric enhancing vs. antagonistic activity on adenosine A1 receptors
2000
International Union of Pharmacology. XXV. Nomenclature and Classification of Adenosine Receptors
2001 Standout
Adenosine receptors: Clinical implications and biochemical mechanisms
1988
The Sympathetic Nerve—An Integrative Interface between Two Supersystems: The Brain and the Immune System
2000 Standout
A cAMP response element in the beta 2-adrenergic receptor gene confers transcriptional autoregulation by cAMP.
1990 StandoutNobel
Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors.
1994
The impact of training informal health care providers in India: A randomized controlled trial
2016 StandoutScienceNobel
Glomeruli and microvessels of the rabbit kidney contain both A1- and A2-adenosine receptors
1987
Chiral Pyrrolo[2,3-d]pyrimidine and Pyrimido[4,5-b]indole Derivatives: Structure−Activity Relationships of Potent, Highly Stereoselective A1-Adenosine Receptor Antagonists,
1996
Inhaled versus oral steroids for adults with chronic asthma
2001
Species differences in high‐affinity adenosine A2 binding sites in striatal membranes from mammalian brain
1988
Section Review: Cardiovascular & Renal: Cyclic nucleotide phosphodiesterases as therapeutic targets in cardiovascular diseases
1995
Nomenclature and classification of purinoceptors.
1994 Standout
Molecular Origin of Blood‐Based Infrared Spectroscopic Fingerprints**
2021 StandoutNobel
Binding of the A1-selective adenosine antagonist 8-cyclopentyl-1,3-dipropylxanthine to rat brain membranes
1987
Transient up-regulation of P2Y2nucleotide receptor mRNA expression is an immediate early gene response in activated thymocytes
1997 StandoutNobel
1,8-Disubstituted Xanthine Derivatives: Synthesis of Potent A2B-Selective Adenosine Receptor Antagonists
2002
Clinical Impact of 18F Fluorodeoxyglucose Positron Emission Tomography in Patients With Non–Small-Cell Lung Cancer: A Prospective Study
2001
A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.
1994
Properties of recombinant adenosine receptors
1993
American Society of Clinical Oncology Treatment of Unresectable Non–Small-Cell Lung Cancer Guideline: Update 2003
2003 Standout
ADP Receptors on Platelets
1996
Cloning, expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis.
1992
Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.
1992
Asymmetric Transition-Metal-Catalyzed Allylic Alkylations: Applications in Total Synthesis
2003 Standout
From Molecules to Crystal Engineering: Supramolecular Isomerism and Polymorphism in Network Solids
2001 Standout
Works of D. Ukena being referenced
Diagnostische Aussagekraft der Positronen-Emissions-Tomographie (PET) bei zerebralen Metastasen von Bronchialkarzinomen
1999
Value of F-18-fluorodeoxyglucose positron emission tomography after induction therapy of locally advanced bronchogenic carcinoma
2004
Characterization of PAF receptors on human neutrophils using the specific antagonist, WEB 2086 Correlation between receptor binding and function
1989
Efficacy and safety of budesonide/formoterol single inhaler therapy versus a higher dose of budesonide in moderate to severe asthma
2004
Effect of Theophylline and Adenosine on Eosinophil Function
1989
Adenosine receptor-blocking xanthines as inhibitors of phosphodiesterase isozymes
1993
Radioligand binding of antagonists of platelet‐activating factor to intact human platelets
1988
Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions
1989
Benzo[1,2-c:5,4-c']dipyrazoles: non-xanthine adenosine antagonists
1988
Tolerance, safety, and kinetics of the new antineoplastic compound dexniguldipine-HCl after oral administration: a phase I dose-escalation trial
1995
8-Aryl- and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors
1988
Non-xanthine heterocycles: Activity as antagonists of A1 and A2-adenosine receptors
1988
Comparison of addition of theophylline to inhaled steroid with doubling of the dose of inhaled steroid in asthma
1997
[3H]WEB 2086 labels platelet activating factor receptors in guinea pig and human lung
1989
Chemotherapy in stage I+II non-small cell lung cancer
2001
A palliative accelerated irradiation regimen (PAIR) for advanced non-small-cell lung cancer (NSCLC)
1996
Beta 2 -Adrenergic Receptors on Eosinophils: Binding and Functional Studies
1990
18F-Deoxyglucose positron emission tomography (FDG-PET) for the planning of radiotherapy in lung cancer: high impact in patients with atelectasis
1999
A palliative accelerated irradiation regimen for advanced non–small-cell lung cancer VS. conventionally fractionated 60 GY: results of a randomized equivalence study
2000
Effect of preoperative chemoradiation in addition to preoperative chemotherapy: a randomised trial in stage III non-small-cell lung cancer
2008
Zardaverine as a selective inhibitor of phosphodiesterase isozymes
1991
First-time treatment with steroids in bronchial asthma: comparison of the effects of inhaled beclomethasone and of oral prednisone on airway function, bronchial reactivity and hypothalamic-pituitary-adrenal axis
1990
Evidence for an A2 adenosine receptor in guinea pig lung
1985
A [3H]amine congener of 1,3‐dipropyl‐8‐phenylxanthine
1986
The protein kinase C activator phorbol‐12‐myristate‐13‐acetate enhances cyclic AMP accumulation in pheochromocytoma cells
1986
Functionalized congeners of 1,3-dipropyl-8-phenylxanthine: Potent antagonists for adenosine receptors that modulate membrane adenylate cyclase in pheochromocytoma cells, platelets and fat cells
1986
Serum anti-p53 antibodies in patients with lung cancer.
2000
Labelling of Ri adenosine receptors in rat fat cell membranes with (?)-[125iodo]N6-hydroxyphenylisopropyladenosine
1984
18FDG beim primären Staging von Lungentumoren
1995
[3H]xanthine amine congener of 1,3-dipropyl-8-phenylxanthine: an antagonist radioligand for adenosine receptors.
1986
Effects of several 5?-carboxamide derivatives of adenosine on adenosine receptors of human platelets and rat fat cells
1984
Analogs of caffeine: Antagonists with selectivity for A2 adenosine receptors
1986
Ra Adenosine receptors in human platelets
1984
Study of Adenosine Receptors in Intact Rat Fat Cells by Radioligand Binding
1985
Xanthine derivatives as antagonists at A1 and A2 adenosine receptors
1985
Cisplatin / etoposide (PE) followed by twice-daily chemoradiation (hfRT/CT) versus PE alone before surgery in stage III non-small cell lung cancer (NSCLC): A randomized phase III trial of the German Lung Cancer Cooperative Group (GLCCG)
2004
Molecular probes for extracellular adenosine receptors
1987
Xanthine functionalized congeners as potent ligands at A2-adenosine receptors
1987
[125I] N6-p-hydroxyphenylisopropyladenosine, a new ligand for Ri adenosine receptors
1982
Definition of subclasses of adenosine receptors associated with adenylate cyclase: interaction of adenosine analogs with inhibitory A1 receptors and stimulatory A2 receptors
1987
Guanine nucleotide and cation regulation of radioligand binding to R i adenosine receptors of rat fat cells
1984
N6-Substituted N-alkyladenosine-5'-uronamides: bifunctional ligands having recognition groups for A1 and A2 adenosine receptors
1986
Effects of N-ethylmaleimide on adenosine receptors of rat fat cells and human platelets
1984
Species differences in structure‐activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors
1986
Demonstration of Ri-type adenosine receptors in bovine myocardium by radioligand binding
1985
N6‐Substituted 9‐methyladenines: A new class of adenosine receptor antagonists
1987