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Citing Papers
The neural basis of drug craving: An incentive-sensitization theory of addiction
1993 Standout
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1996 StandoutNature
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1993
Methods for drug discovery: development of potent, selective, orally effective cholecystokinin antagonists
1988
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1994
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2005 StandoutNobel
[26] Synthesis and evaluation of 1,4-benzodiazepine libraries
1996
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Drugs acting on brain dopamine receptors: A conceptual re-evaluation five years after the first selective D-1 antagonist
1989
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2003 Standout
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1997 Nature
Structure of the δ-opioid receptor bound to naltrindole
2012 StandoutNatureNobel
Differential Roles of Opioid Receptors in Respiration, Respiratory Disease, and Opiate-induced Respiratory Depression
1990
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2003
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2004 Standout
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2004 StandoutNobel
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1998 Nobel
The immunocytochemical localization of enkephalin in the central nervous system of the rat
1981
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Bioorganometallic Chemistry of Ferrocene
2004 Standout
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1977
Tandem Catalysis: Three Mechanistically Distinct Reactions from a Single Ruthenium Complex
2000 StandoutNobel
Animal Models of Nociception
2001
Chemistry of Polyvalent Iodine
2008 Standout
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
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1983 StandoutNature
Solid-phase synthesis of diverse tetrahydro-1,4-benzodiazepine-2-ones
1997
Protein β-turn mimetics I. Design, synthesis, and evaluation in model cyclic peptides.
1993
Narcotic analgetics: CNS sites and mechanisms of action as revealed by intracerebral injection techniques
1977 Standout
Conformation of [Leu5]Enkephalin from X-Ray Diffraction: Features Important for Recognition at Opiate Receptor
1978 Science
Effects of peptides of pituitary origin on the formation of C21 steroid by fetal calf adrenal cells in culture
1977 StandoutNobel
Motivational properties of kappa and mu opioid receptor agonists studied with place and taste preference conditioning
1985
First Highly Enantioselective Synthesis of Benzodiazepinones by Catalytic Hydrogenation
2010
β-endorphin induced akinesia in rats: Effect of apomorphine and α-methyl-p-tyrosine and related modifications of dopamine turnover in the basal ganglia
1977
The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library.
1994
Practical Methodologies for the Synthesis of Indoles
2006 Standout
Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs.
1976 StandoutNobel
Endorphins: Profound Behavioral Effects in Rats Suggest New Etiological Factors in Mental Illness
1976 StandoutScienceNobel
The Current Status of Heterocyclic Combinatorial Libraries
1997
[2‘,6‘-Dimethyltyrosine]Dynorphin A(1−11)-NH2Analogues Lacking an N-Terminal Amino Group: Potent and Selective κ Opioid Antagonists
2001
THE ENDORPHINS, NOVEL PEPTIDES OF BRAIN AND HYPOPHYSIAL ORIGIN, WITH OPIATE‐LIKE ACTIVITY: BIOCHEMICAL AND BIOLOGIC STUDIES
1977 StandoutNobel
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1977 StandoutNatureNobel
β-Endorphin: Endogenous Opiate or Neuroleptic?
1977 StandoutScienceNobel
Properties of a selective kappa agonist, U-50,488H
1982
Regional dissociation of beta-endorphin and enkephalin contents in rat brain and pituitary.
1977 StandoutNobel
Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats.
1988 Standout
Enhanced Rewarding Properties of Morphine, but not Cocaine, in βarrestin-2 Knock-Out Mice
2003 StandoutNobel
Effects of enkephalin and morphine on Renshaw cells in feline spinal cord
1976 Nature
Evidence for a kappa-opioid receptor on pituitary astrocytes: An autoradiographic study
1985
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
A Field Guide to Foldamers
2001 Standout
Enkephalin: conformational analysis by means of empirical energy calculations.
1977
Organic Chemistry on Solid Supports
1996
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
2001 StandoutNobel
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Organische Chemie an fester Phase
1996
Preference conditioning produced by opioid active and inactive isomers of levorphanol and morphine in rat
1986
Crystal structure of leucine-enkephalin
1983 StandoutNatureNobel
Pathophysiology of Sleep Apnea
2010 Standout
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Cannabinoid receptor localization in brain.
1990 Standout
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2002
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Advances in Synthetic Applications of Hypervalent Iodine Compounds
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2009 Standout
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1977 StandoutScienceNobel
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1976 StandoutNobel
Solid-Phase Synthesis of Libraries Generated from a 4-Phenyl-2-carboxy-piperazine Scaffold
2001
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1993
Synthesis and Applications of Small Molecule Libraries
1996
An Analog of Enkephalin Having Prolonged Opiate-Like Effects in Vivo
1977 StandoutScienceNobel
Animal models of nociception.
2001
Opioid activity of synthetic and naturally occurring enkephalin peptides
1979 StandoutNobel
D 1 and D 2 Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons
1990 StandoutScience
Novel “Restoration of Function” Mutagenesis Strategy to Identify Amino Acids of the δ-Opioid Receptor Involved in Ligand Binding
1997
The C-Fragment of β-Lipotropin: An Endogenous Neuroleptic or Antipsychotogen?
1976 Science
Enkephalin-like immunoreactivity in gland cells and nerve terminals of the adrenal medulla
1978
Dopamine Receptors: From Structure to Function
1998 Standout
Opioid and Nonopioid Mechanisms of Stress Analgesia
1980 StandoutScience
Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study.
1977 StandoutNobel
Behavioral effects of a novel kappa opioid analgesic, U-50488, in rats and rhesus monkeys
1985
Morphine- and opioid peptide-induced inhibition of the release of dopamine from tuberoinfundibular neurons
1979
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The pharmacological properties of a new, orally active antianaphylactic compound: ketotifen, a benzocycloheptathiophene.
1978
CY 208–243: A unique combination of atypical opioid antinociception and D1 dopaminomimetic properties
1988
Bremazocine: A potent, long-acting opiate kappa-agonist
1980
Pharmacological evaluation of mild analgesics.
1980
An opioid benzodiazepine
1982 Nature
Evidence for analgesic activity of enkephalin in the mouse
1976 Nature