Citation Impact
Citing Papers
The Neural Basis of Economic Decision-Making in the Ultimatum Game
2003 StandoutScience
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Suppression of Aging in Mice by the Hormone Klotho
2005 StandoutScience
Metabolic Syndrome and Altered Gut Microbiota in Mice Lacking Toll-Like Receptor 5
2010 StandoutScience
Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains
2012
Influence of Insulin in the Ventromedial Hypothalamus on Pancreatic Glucagon Secretion In Vivo
2010
Insights into insulin resistance and type 2 diabetes from knockout mouse models
2000
Insulin's direct effects on the liver dominate the control of hepatic glucose production
2006
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Impaired Glucose Tolerance as a Disorder of Insulin Action
1988
Inflammation and metabolic disorders
2006 StandoutNature
Angiotensin II and the endocrine pancreas: effects on islet blood flow and insulin secretion in rats
1998
Dynamics of fat cell turnover in humans
2008 StandoutNature
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
2002 StandoutNature
Central nervous system control of food intake and body weight
2006 StandoutNature
Congenital leptin deficiency is associated with severe early-onset obesity in humans
1997 StandoutNature
The psychobiology of meals
1994
The evaluation of insulin as a metabolic signal influencing behavior via the brain
1996
Insulin granule dynamics in pancreatic beta cells
2003
Obesity, diabetes and the central nervous system
1998
Induction of angiogenesis during the transition from hyperplasia to neoplasia
1989 StandoutNature
Localization and Characterization of Insulin Receptors in Rat Brain and Pituitary Gland Usingin VitroAutoradiography and Computerized Densitometry*
1987
Impaired insulin action in the human brain: causes and metabolic consequences
2015
Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease.
1997
Insulin activates ATP-sensitive K+ channels in hypothalamic neurons of lean, but not obese rats
2000
The Role of Insulin Resistance in the Pathogenesis of Alzheimer??s Disease
2003
Central nervous system control of food intake
2000 StandoutNature
The Timing of Meals.
2004
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Increased hypothalamic neuropeptide Y expression following food deprivation
1990
The role of insulin receptor signaling in the brain
2005
Recombinant ob protein reduces feeding and body weight in the ob/ob mouse.
1995
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Pharmacologic and Therapeutic Applications of alpha2-Adrenoceptor Subtypes
1993
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Similar reduction of first- and second-phase B-cell responses at three different glucose levels in type II diabetes and the effect of gliclazide therapy
1989
Oxytocin increases trust in humans
2005 StandoutNature
Abnormal splicing of the leptin receptor in diabetic mice
1996 StandoutNature
Western Diet Modulates Insulin Signaling, c-Jun N-Terminal Kinase Activity, and Insulin Receptor Substrate-1ser307 Phosphorylation in a Tissue-Specific Fashion
2005
Animal models of obesity and diabetes mellitus
2018
Brain insulin action augments hepatic glycogen synthesis without suppressing glucose production or gluconeogenesis in dogs
2011
Insulin and leptin: dual adiposity signals to the brain for the regulation of food intake and body weight
1999
Leptin and the regulation of body weight in mammals
1998 StandoutNature
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Importance of Early Phase Insulin Secretion to Intravenous Glucose Tolerance in Subjects with Type 2 Diabetes Mellitus
2001
Differential Sensitivity of Men and Women to Anorexigenic and Memory-Improving Effects of Intranasal Insulin
2008
Role of leptin in the neuroendocrine response to fasting
1996 StandoutNature
Obesity Wars
2004
Immunomodulators and feeding regulation: A humoral link between the immune and nervous systems
1989
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes
2003 Standout
Cerebrospinal fluid leptin levels: Relationship to plasma levels and to adiposity in humans
1996
Some Aspects of the Biological Role of Adenosine 3',5'-monophosphate (Cyclic AMP)
1968 StandoutNobel
Identification of the predominant substrate for ADP-ribosylation by islet activating protein.
1983 StandoutNobel
Alpha-Adrenergic Receptor Subtypes
1980 StandoutNobel
Influence of sympathectomy on body weight of rats given chow or supermarket diets
1985
βAR Signaling Required for Diet-Induced Thermogenesis and Obesity Resistance
2002 StandoutScienceNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
Islet-activating protein. Enhanced insulin secretion and cyclic AMP accumulation in pancreatic islets due to activation of native calcium ionophores.
1979
Signals That Regulate Food Intake and Energy Homeostasis
1998 Science
Dietary restriction increases insulin sensitivity and lowers blood glucose in rhesus monkeys
1994
Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System
2000 StandoutScienceNobel
A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum
2000 StandoutNobel
Pertussis toxin induces structural changes in G alpha proteins independently of ADP-ribosylation.
1989 StandoutNobel
Direct Demonstration of Impaired Functionality of a Purified Desensitized β-Adrenergic Receptor in a Reconstituted System
1984 StandoutScienceNobel
Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.
1995
Decreased insulin production and increased insulin sensitivity in the klotho mutant mouse, a novel animal model for human aging
2000
Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice
2008 StandoutNobel
Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
1985 Standout
Neuroanatomical correlates of hunger and satiation in humans using positron emission tomography
1999
Insulin and insulin-like growth factors in the CNS
1988
Cardiovascular Regulation in Mice Lacking α 2 -Adrenergic Receptor Subtypes b and c
1996 StandoutScienceNobel
Regulation of noradrenaline release by presynaptic receptor systems
1977
Oxidative Stress, Caloric Restriction, and Aging
1996 StandoutScience
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
1979 Nature
Signals and Pools Underlying Biphasic Insulin Secretion
2002
Smoking and its effects on body weight and the systems of caloric regulation
1982
A genetically clamped renin transgene for the induction of hypertension
2002 StandoutNobel
Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.
1978 StandoutNobel
Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons
1988
Low plasma leptin levels contribute to diabetic hyperphagia in rats.
1999
Glucose clamp technique: a method for quantifying insulin secretion and resistance.
1979 Standout
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Characterization of the binding of 125-I-labeled epidermal growth factor to human fibroblasts
1975 StandoutNobel
Adiposity signals and food reward: expanding the CNS roles of insulin and leptin
2003
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Effects of Endurance Training on Glucose Tolerance and Plasma Lipid Levels in Older Men and Women
1984
A Receptor Mechanism for the Inhibition Of Insulin Release by Epinephrine in Man*
1967
Effects of an Angiotensin-Converting–Enzyme Inhibitor, Ramipril, on Cardiovascular Events in High-Risk Patients
2000 Standout
Role of the CNS Melanocortin System in the Response to Overfeeding
1999
Effects of Intensive Glucose Lowering in Type 2 Diabetes
2008 Standout
Hypophysial Responses to Continuous and Intermittent Delivery of Hypothalamic Gonadotropin-Releasing Hormone
1978 StandoutScience
Cardiovascular events and correlates in the Veterans Affairs Diabetes Feasibility Trial. Veterans Affairs Cooperative Study on Glycemic Control and Complications in Type II Diabetes.
1997
Defect in insulin binding to receptors in obese man. Amelioration with calorie restriction.
1975
Insulin-Dependent Regulation of Insulin Receptor Concentrations: A Direct Demonstration in Cell Culture
1974
Glucose control of basal insulin secretion in diabetes
1977
INSULIN RATHER THAN GLUCOSE HOM$OElig;OSTASIS IN THE PATHOPHYSIOLOGY OF DIABETES
1976
Carbohydrate Homeostasis
1970
Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans
2016
Hypothalamic and Striatal Insulin Action Suppresses Endogenous Glucose Production and May Stimulate Glucose Uptake During Hyperinsulinemia in Lean but Not in Overweight Men
2017
Sniffing neuropeptides: a transnasal approach to the human brain
2002
Inhibition of food intake in response to intestinal lipid is mediated by cholecystokinin in humans
1999
Stimulation of Insulin Secretion by Theophylline
1967 Nature
Gut hormone PYY3-36 physiologically inhibits food intake
2002 StandoutNature
Catecholamine-induced subsensitivity of adenylate cyclase associated with loss of beta-adrenergic receptor binding sites.
1975 StandoutNobel
Inhibition of hypothalamic neuropeptide Y gene expression by insulin.
1992
Human Aging: Usual and Successful
1987 StandoutScience
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
2000 StandoutScience
Response : Nitric Oxide and Arginine-Evoked Insulin Secretion
1992 StandoutScienceNobel
Effects of Somatostatin on Plasma Glucose and Glucagon Levels in Human Diabetes Mellitus
1974 StandoutNobel
Works of D. Porte being referenced
Insulin Resistance andβ-Cell Dysfunction in Aging: The Importance of Dietary Carbohydrate*
1988
Effect of diet-induced obesity and experimental hyperinsulinemia on insulin uptake into CSF of the rat
1993
Identification of Binding Sites for an Insulin-like Growth Factor (IGF-1) in the Median Eminence of the Rat Brain by Quantitative Autoradiography
1986
Islet Function and Insulin Sensitivity in the Non‐diabetic Offspring of Conjugal Type 2 Diabetic Patients
1990
Peptides and the control of meal size
1981
Endocrine regulation of food intake and body weight
1996
Evidence for entry of plasma insulin into cerebrospinal fluid through an intermediate compartment in dogs. Quantitative aspects and implications for transport.
1991
Saturable transport of insulin from plasma into the central nervous system of dogs in vivo. A mechanism for regulated insulin delivery to the brain.
1993
Regulation of food intake and body weight by insulin
1981
Disproportionate elevation of immunoreactive proinsulin in Type 2 (non-insulin-dependent) diabetes mellitus and in experimental insulin resistance
1987
Intraventricular CCK inhibits food intake and gastric emptying in baboons
1989
Control of insulin secretion by catecholamines, stress, and the sympathetic nervous system.
1973
Regulation of food intake and body weight in insulin.
1981
Human Insulin Secretion: An Integrated Approach
1970
Short-term hyperglycemia and hyperinsulinemia improve insulin action but do not alter glucose action in normal humans
1992
Brain and Liver Insulin Binding Is Decreased in Zucker Rats Carrying the ’fa’ Gene*
1985
Acute and chronic effects of sulfonylurea drugs on pancreatic islet function in man.
1984
Brain insulin binding is decreased in Wistar Kyoto rats carrying the ‘fa’ gene
1986
Suppression of food intake by intravenous nutrients and insulin in the baboon
1984
Effect of Force-Feeding Upon Basal Insulin Levels of Rats
1975
Basal and stimulated hyperinsulinism: reversible metabolic sequelae of obesity.
1974
Diminished B cell secretory capacity in patients with noninsulin-dependent diabetes mellitus.
1984
A re-assessment of the regulation of adiposity and appetite by the brain insulin system.
1990
Insulin: its relationship to the central nervous system and to the control of food intake and body weight
1985
Dexamethasone-induced insulin resistance enhances B cell responsiveness to glucose level in normal men
1984
Effect of fasting interval on CCK-8 suppression of food intake in the baboon
1986
A role for alpha-adrenergic receptors in abnormal insulin secretion in diabetes mellitus.
1976
Intracisternal insulin alters sensitivity to CCK-induced meal suppression in baboons
1986
Insulin responses to glucose: evidence for a two pool system in man
1969
Intraventricular CCK-8 reduces single meal size in the baboon by interaction with type-A CCK receptors
1992
Neural control of the endocrine pancreas.
1974
Insulin in the Brain
1987
Neuropharmacology of the Pancreatic Islets
1976
Adaptation of B and A cell function during prolonged glucose infusion in human subjects
1984
Cerebrospinal Fluid Insulin Levels Increase During Intravenous Insulin Infusions in Man*
1987
Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion
1986
Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid.
1990
Intraventricular insulin reduces food intake and body weight of lean but not obese zucker rats
1986
Relationship between plasma and cerebrospinal fluid insulin levels of dogs.
1977
Pathogenesis of Age-Related Glucose Intolerance in Man: Insulin Resistance and Decreased β-Cell Function*
1985
The effect of epinephrine on immunoreactive insulin levels in man.
1966