Citation Impact
Citing Papers
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Probing p53 biological functions through the use of genetically engineered mouse models
2005
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
The p53 protein and its interactions with the oncogene products of the small DNA tumor viruses
1990
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
Genetic instabilities in human cancers
1998 StandoutNature
A genetic model for colorectal tumorigenesis
1990 Standout
An internal deletion within an 11p13 zinc finger gene contributes to the development of Wilms' tumor
1990
When Checkpoints Fail
1997 StandoutNobel
Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
1996 StandoutNature
The role of p53 in tumour suppression: lessons from mouse models
1999
APC mutations occur early during colorectal tumorigenesis
1992 StandoutNature
The Hallmarks of Cancer
2000 Standout
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6
1991 StandoutNature
COMMENTARY: p53 Tumor suppressor gene: from the basic research laboratory to the clinic—an abridged historical perspective
1996
Short Telomeres, even in the Presence of Telomerase, Limit Tissue Renewal Capacity
2005 StandoutNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
The 1993 Walter Hubert Lecture: the role of the p53 tumour-suppressor gene in tumorigenesis
1994
The p53 tumour suppressor gene
1991 StandoutNature
Increased expression of mutant forms of p53 oncogene in primary lung cancer
1990
Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation
1998
Genetic instability in colorectal cancers
1997 StandoutNature
A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types
1994 StandoutScience
p53 Mutations: Gains or losses?
1991
Molecular themes in oncogenesis
1991 StandoutNobel
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
1992 StandoutNature
p53 is required for radiation-induced apoptosis in mouse thymocytes
1993 StandoutNature
Disrupted dichotomous intracellular control of human papillomavirus infection in cancer of the cervix
1994 StandoutNobel
p63 is a p53 homologue required for limb and epidermal morphogenesis
1999 StandoutNature
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
p53 mutant mice that display early ageing-associated phenotypes
2002 Nature
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
1992
Low frequency of the p53 gene mutations in neuroblastoma
1994
p53 Mutations in Human Cancers
1991 StandoutScience
p53 mutations in human lymphoid malignancies: association with Burkitt lymphoma and chronic lymphocytic leukemia.
1991
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
1994 StandoutScience
Tumor Suppressor Genes: The Puzzle and the Promise
1989 Science
Apoptosis in the Pathogenesis and Treatment of Disease
1995 StandoutScience
p53 Functions as a Cell Cycle Control Protein in Osteosarcomas
1990
Cancer Cell Cycles
1996 StandoutScience
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
Frequency and structure of p53 rearrangements in human osteosarcoma.
1990
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms
1990 StandoutScience
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.
1995
p53 functions as a cell cycle control protein in osteosarcomas.
1990
Activation of the ATM Kinase by Ionizing Radiation and Phosphorylation of p53
1998 StandoutScience
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines.
1993 StandoutNobel
p53: A Frequent Target for Genetic Abnormalities in Lung Cancer
1989 StandoutScience
Metabolic reprogramming and cancer progression
2020 StandoutScience
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
Growth Factors and Cancer
1991 StandoutScience
Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells.
1993
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
p53: At the Crossroads of Molecular Carcinogenesis and Risk Sssessment
1993 Science
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.
1990
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.
1996
p53 mutations increase resistance to ionizing radiation.
1993
Association of Human Papillomavirus Types 16 and 18 E6 Proteins with p53
1990 StandoutScience
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma.
1991 Standout
Role of the cdc25C phosphatase in G2 arrest induced by nitrogen mustard.
1994 StandoutNobel
Suppression of Human Colorectal Carcinoma Cell Growth by Wild-Type p53
1990 StandoutScience
Works of D. Mock being referenced
High incidence of lung, bone, and lymphoid tumors in transgenic mice overexpressing mutant alleles of the p53 oncogene.
1989