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Citing Papers
PHARMACOKINETIC AND PHARMACODYNAMIC ASPECTS OF THERAPY OF EXPERIMENTAL ENDOCARDITIS
1993
Control of Peripheral Nerve Myelination by the ß-Secretase BACE1
2006 Science
Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society
2016 Standout
Infective Endocarditis
2005 Standout
Phenotypic and Biochemical Analyses of BACE1- and BACE2-deficient Mice
2005
Platelets in defense against bacterial pathogens
2009
Synthesis of carbocyclic nucleosides
1994
Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications
2015 Standout
A genomic perspective on human proteases as drug targets
2001
Treatment Strategies Targeting Amyloid -Protein
2012
MR imaging of the peripheral nervous system
1994
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
In Vivo Postantibiotic Effect in a Thigh Infection in Neutropenic Mice
1988
The Role of Platelets in Antimicrobial Host Defense
1997
ST2 is an inhibitor of interleukin 1 receptor and Toll-like receptor 4 signaling and maintains endotoxin tolerance
2004
Individualised antibiotic dosing for patients who are critically ill: challenges and potential solutions
2014 Standout
Interrelationship between pharmacokinetics and pharmacodynamics in determining dosage regimens for broad-spectrum cephalosporins
1995
Piperacillin penetration into tissue of critically ill patients with sepsis—Bolus versus continuous administration?
2009
State‐of‐the‐Art Clinical Article: Pharmacokinetic/Pharmacodynamic Parameters: Rationale for Antibacterial Dosing of Mice and Men
1998 Standout
Trafficking and Proteolytic Processing of APP
2012
Modulation of Protein–Protein Interactions with Small Organic Molecules
2003
Target site penetration of fosfomycin in critically ill patients
2003
Therapeutic drug monitoring of β-lactams in critically ill patients: proof of concept
2010
Comparative Antibiotic Dose-Effect Relations at Several Dosing Intervals in Murine Pneumonitis and Thigh-Infection Models
1989
Ceftriaxone diffusion into cardiac fibrin vegetation. Qualitative and quantitative evaluation by autoradiography
1991
Plasma and tissue pharmacokinetics of cefpirome in patients with sepsis
2002
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Bacterial biofilms: from the Natural environment to infectious diseases
2004 Standout
Toll-like receptor signalling
2004 Standout
Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy
2010 Standout
The Evolving Role of Chemical Synthesis in Antibacterial Drug Discovery
2014
Neurovascular regulation in the normal brain and in Alzheimer's disease
2004 Standout
Autophagy in the Pathogenesis of Disease
2008 Standout
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
Flotillin-Dependent Clustering of the Amyloid Precursor Protein Regulates Its Endocytosis and Amyloidogenic Processing in Neurons
2008 StandoutNobel
Alzheimer's disease
2016 Standout
Progress and problems with the use of viral vectors for gene therapy
2003 Standout
Mechanisms of Antimicrobial Peptide Action and Resistance
2003 Standout
Antibiotic Dosing in Multiple Organ Dysfunction Syndrome
2011
The post-antibiotic sub-MIC effect in vitro and in vivo
1993
Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice
2005 Standout
Multiple Effects of Aspartate Mutant Presenilin 1 on the Processing and Trafficking of Amyloid Precursor Protein
2001
Antimicrobial peptides from platelets
1999
Attenuated multi–mutated herpes simplex virus–1 for the treatment of malignant gliomas
1995
Compartmentalization of β-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts
2001
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Impaired target site penetration of β -lactams may account for therapeutic failure in patients with septic shock
2001
Pharmacodynamics and pharmacokinetics of SQ109, a new diamine‐based antitubercular drug
2004
Pharmacokinetic issues for antibiotics in the critically ill patient
2009
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
2007 Standout
Intracellular amyloid-β in Alzheimer's disease
2007 Standout
Infective endocarditis
2004 Standout
Substrate and Inhibitor Profile of BACE (β-Secretase) and Comparison with Other Mammalian Aspartic Proteases
2002
The amyloid state and its association with protein misfolding diseases
2014 Standout
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Thrombosis as an intravascular effector of innate immunity
2012 Standout
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Correlation of Antimicrobial Pharmacokinetic Parameters with Therapeutic Efficacy in an Animal Model
1988
IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines
2005 Standout
Role of Antimicrobial Pharmacokinetics and Pharmacodynamics in Surgical Prophylaxis
1991
Direct Detection of Bacterial Biofilms on the Middle-Ear Mucosa of Children With Chronic Otitis Media
2006 Standout
The amyloid hypothesis of Alzheimer's disease at 25 years
2016 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Relevance of Soft-Tissue Penetration by Levofloxacin for Target Site Bacterial Killing in Patients with Sepsis
2003
Penetration of Ciprofloxacin into the Interstitial Space of Inflamed Foot Lesions in Non-Insulin-Dependent Diabetes Mellitus Patients
1999
Biofilms: Survival Mechanisms of Clinically Relevant Microorganisms
2002 Standout
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals
2014 Standout
Relative efficacies of broad-spectrum cephalosporins for treatment of methicillin-susceptible Staphylococcus aureus experimental infective endocarditis
1993
Inclusion-body myositis
2006
In Vitro Characterization of the Presenilin-Dependent γ-Secretase Complex Using a Novel Affinity Ligand
2003
Magnetic Iron Oxide Nanoparticles: Synthesis, Stabilization, Vectorization, Physicochemical Characterizations, and Biological Applications
2008 Standout
β‐Lactamase inhibitors
1983
Bacterial Biofilms: An Emerging Link to Disease Pathogenesis
2003 Standout
Therapeutic Efficacy of Continuous Versus Intermittent Administration of Ceftazidime in an Experimental Klebsiella pneumoniae Pneumonia in Rats
1985
A morphological study of experimental staphylococcal endocarditis and aortitis. II. Inter-relationship of bacteria, vegetation and cardiovasculature in established infections.
1986
Three Decades of β-Lactamase Inhibitors
2010 Standout
β-Lactam Antibiotics: Structural Relationships Affecting in Vitro Activity and Pharmacologic Properties
1986
A Field Guide to Foldamers
2001 Standout
Pharmacokinetics of Unbound Linezolid in Plasma and Tissue Interstitium of Critically Ill Patients after Multiple Dosing Using Microdialysis
2006
Wound Healing: A Cellular Perspective
2018 Standout
Subcellular Partitioning and Intramacrophage Selectivity of Antimicrobial Compounds against Mycobacterium tuberculosis
2017 StandoutNobel
The Crisis in Antibiotic Resistance
1992 StandoutScience
Recent advances in the synthesis of fluorinated nucleosides
2009
Alzheimer's Disease: Molecular Understanding Predicts Amyloid-Based Therapeutics
2003
2012 Infectious Diseases Society of America Clinical Practice Guideline for the Diagnosis and Treatment of Diabetic Foot Infectionsa
2012 Standout
Inhibition of Toll-like Receptor and Cytokine Signaling—A Unifying Theme in Ischemic Tolerance
2004 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Exclusively targeting β-secretase to lipid rafts by GPI-anchor addition up-regulates β-site processing of the amyloid precursor protein
2003
Biogenesis of γ-secretase early in the secretory pathway
2007 StandoutNobel
Value of antibiotic levels in serum and cardiac vegetations for predicting antibacterial effect of ceftriaxone in experimental Escherichia coli endocarditis
1987
GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large
2006 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Applications of Fluorine in Medicinal Chemistry
2015 Standout
Alzheimer's Disease and the Amyloid-β Peptide
2010
Cleavage of Amyloid-β Precursor Protein and Amyloid-β Precursor-like Protein by BACE 1
2004 StandoutNobel
Works of D. M. Ryan being referenced
Pharmacokinetics of antibiotics in natural and experimental superficial compartments in animals and humans
1993
Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxyguanosines
1991
ASP1 (BACE2) Cleaves the Amyloid Precursor Protein at the β-Secretase Site
2000
Ribonucleotide Reductase Encoded by Herpes Simplex Virus Is a Determinant of the Pathogenicity of the Virus in Mice and a Valid Antiviral Target
1988
A problem in the interpretation of β-lactam antibiotic levels in tissues
1983
Penetration of β-lactam antibiotics into cardiac vegetations, aorta and heart muscle in experimental Staphylococcus aureus endocarditis: comparison of ceftazidime, cefuroxime and methicillin
1985
Cefuroxime - A new cephalosporin antibiotic.
1976
GR 20263, a new broad-spectrum cephalosporin with anti-pseudomonal activity
1980
A morphological study of experimental rabbit staphylococcal endocarditis and aortitis. I. Formation and effect of infected and uninfected vegetations on the aorta.
1986
Simultaneous comparison of three methods for assessing ceftazidime penetration into extravascular fluid
1982
Experimental staphylococcal endocarditis and aortitis
1986
The Use of Antibiotic Serum Levels to Predict Concentrations in Tissues
1986
Bacterial filamentation and in vivo efficacy: a comparison of several cephalosporins
1981
Antibiotic Assays in Muscle: Are Conventional Tissue Levels Misleading as Indicator of the Antibacterial Activity?
1980
Comparative pharmacokinetics of ceftazidime in fibrin clots and cardiac vegetations in rabbits with Staphylococcus aureus endocarditis
1985
Guidelines for the welfare of animals in rodent protection tests: A Report from the Rodent Protection Test Working Party
1994
Comparison of ceftazidime, cefuroxime and methicillin in the treatment of Staphylococcus aureus endocarditis in rabbits
1984
Evaluation of ceftazidime in experimental Klebsiella pneumoniae pneumonia: comparison with other antibiotics and measurement of its penetration into respiratory tissues and secretions
1986