Citation Impact
Citing Papers
Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility
2003 StandoutNobel
Normal gut microbiota modulates brain development and behavior
2011 Standout
Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia
2006 StandoutScience
Resting Microglial Cells Are Highly Dynamic Surveillants of Brain Parenchyma in Vivo
2005 StandoutScience
The Innate Immune Response Differs in Primary and Secondary Salmonella Infection
2002
Group A Streptococcus Activates Type I Interferon Production and MyD88-dependent Signaling without Involvement of TLR2, TLR4, and TLR9
2008 StandoutNobel
High incidence of serum antibodies to Escherichia coli O157 lipopolysaccharide in children with hemolytic-uremic syndrome
1991
Toll-Like Receptor-5 and the Innate Immune Response to Bacterial Flagellin
2002
Within the twilight zone: a sensitive profile-profile comparison tool based on information theory
2002 StandoutNobel
Crystal structure of the cell-binding B oligomer of verotoxin-1 from E. coli
1992 Nature
Innate immune sensing and its roots: the story of endotoxin
2003 StandoutNobel
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
2007 Standout
Inducible Nitric-oxide Synthase and Nitric Oxide Production in Human Fetal Astrocytes and Microglia
1997 StandoutNobel
Microglia-mediated neurotoxicity: uncovering the molecular mechanisms
2006 Standout
Diarrheal and Environmental Isolates of Aeromonas spp. Produce a Toxin Similar to Shiga-Like Toxin 1
1996
Shiga Toxin: Purification, Structure, and Function
1991
Molecular cloning and nucleotide sequence of another variant of the Escherichia coli Shiga-like toxin II family
1990
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
2001 StandoutNature
Microglia in degenerative neurological disease
1993
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
2005 Standout
Microglia: Intrinsic immuneffector cell of the brain
1995
ATP mediates rapid microglial response to local brain injury in vivo
2005 Standout
Microglia: a sensor for pathological events in the CNS
1996 Standout
Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling
2003 StandoutNobel
Cloning and nucleotide sequencing of Vero toxin 2 variant genes from Escherichia coli O91 : H21 isolated from a patient with the hemolytic uremic syndrome
1990
Importance of arginine at position 170 of the A subunit of Vero toxin 1 produced by enterohemorrhagic Escherichia coli for toxin activity
1991
Prevalence of F107 fimbriae on Escherichia coli isolated from pigs with oedema disease or postweaning diarrhoea
1994
Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6
2001
Escherichia coli cytotoxins and enterotoxins
1992
The pathogenesis of edema disease in pigs. A review
1992
Use of mixed infections to study cell invasion and intracellular proliferation of Salmonella enterica in eukaryotic cell cultures
2003
Investigation of Shiga-like Toxin Binding to Chemically Synthesized Oligosaccharide Sequences
1991
Cloning and nucleotide sequence of a variant Shiga-like toxin II gene from Escherichia coli OX3:H21 isolated from a case of sudden infant death syndrome
1992
Cytotoxicity of microglia
1993
Pathogenic Escherichia coli
2004 Standout
Evidences for vagus nerve in maintenance of immune balance and transmission of immune information from gut to brain in STM-infected rats
2002
Microglial motility in the rat facial nucleus following peripheral axotomy
1999
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Escherichia coliHarboring Shiga Toxin 2 Gene Variants: Frequency and Association with Clinical Symptoms
2002
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
The Classical Complement Cascade Mediates CNS Synapse Elimination
2007 Standout
Identification of Shiga-like toxin type II producing Escherichia coli using the polymerase chain reaction and a digoxigenin labelled DNA probe
1992
AB5 toxins: structures and inhibitor design
2000
Functions of Bacterial Flagella
1996
Two distinct binding sites for globotriaosyl ceramide on verotoxins: identification by molecular modelling and confirmation using deoxy analogues and a new glycolipid receptor for all verotoxins
1996
Increase of macrophage colony‐stimulating factor and granulocyte‐macrophage colony‐stimulating factor receptors in the regenerating rat facial nucleus
1991
Sequence of a variant Shiga-like toxin type-I operon of Escherichia coli O111:H−
1993
Non-radioactively labelled polynucleotide and oligonucleotide DNA probes, for selectively detecting Escherichia coli strains producing Vero cytotoxins VT1, VT2 and VT2 variant
1991
The Dark Side of the Salad: Salmonella typhimurium Overcomes the Innate Immune Response of Arabidopsis thaliana and Shows an Endopathogenic Lifestyle
2008 StandoutNobel
The P2Y12 receptor regulates microglial activation by extracellular nucleotides
2006 StandoutNobel
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
2012 Standout
Cloning and Sequencing of a Shiga-like Toxin II-Related Gene from Escherichia coli O157: H7 Strain 7279
1992
Crystal structure of the 30 s ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 s RNA
2002 StandoutNobel
A method for detecting Shiga toxin and Shiga-like toxin-l in pure and mixed culture
1990
Host–Pathogen Coevolution: The Selective Advantage of Bacillus thuringiensis Virulence and Its Cry Toxin Genes
2015
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain
2005 StandoutNature
Isolation of vero cytotoxin-producingEscherichia coli serotypes O9ab:H- and O101:H-carrying VT2 variant gene sequences from a patient with haemolytic uraemic syndrome
1994
Heterogeneity of the amino-acid sequences of Escherichia coli shiga-like toxin type-I operons
1995
Complement and cytokine gene expression in cultured microglia derived from postmortem human brains
1995
The role of Toll-like receptors in host defense against microbial infection
2001
Regulation of Enteric Endophytic Bacterial Colonization by Plant Defenses
2005
Infective endocarditis
2004 Standout
Flagellin Suppresses Epithelial Apoptosis and Limits Disease during Enteric Infection
2006
Cloning and nucleotide sequence analysis of the genes determining verocytotoxin production in a porcine edema disease isolate of Escherichia coli
1988
Insights into the Replisome from the Structure of a Ternary Complex of the DNA Polymerase III α-Subunit
2008 StandoutNobel
Evidence for participation of the macrophage in Shiga-like toxin II-induced lethality in mice
1990
Ribosomal protein structures: insights into the architecture, machinery and evolution of the ribosome
1998 StandoutNobel
Pathogen Recognition and Innate Immunity
2006 Standout
Antifouling Coatings: Recent Developments in the Design of Surfaces That Prevent Fouling by Proteins, Bacteria, and Marine Organisms
2010 Standout
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner
2012 Standout
A bacteriolytic agent that detects and kills Bacillus anthracis
2002 Nature
Two copies of Shiga-like toxin II-related genes common in enterohemorrhagic Escherichia coli strains are responsible for the antigenic heterogeneity of the O157:H- strain E32511
1991
Globotetraosylceramide Is Recognized by the Pig Edema Disease Toxin
1989
A segment of cold shock protein directs the folding of a combinatorial protein
2005 StandoutNobel
Purification and some properties of a Vero toxin from a human strain of Escherichia coli that is immunologically related to Shiga-like toxin II (VT2)
1989
Transcription of the Shiga-like toxin type II and Shiga-like toxin type II variant operons of Escherichia coli
1990
Hybridization of Escherichia coli producing Shiga-like toxin I, Shiga-like toxin II, and a variant of Shiga-like toxin II with synthetic oligonucleotide probes
1989
Evaluation of a technique for identification of Shiga-like toxin-producing Escherichia coli by using polymerase chain reaction and digoxigenin-labeled probes
1993
Magnetic resonance imaging and histopathological study of brain lesions in rabbits given intravenous verotoxin 2
1996
Rapid and specific detection of verotoxin genes in Escherichia coli by the polymerase chain reaction
1990
Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants
1990
Evidence that verotoxins (Shiga-like toxins) from Escherichia coli bind to P blood group antigens of human erythrocytes in vitro
1994
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
2017 Standout
Identification of verotoxin type 2 variant B subunit genes in Escherichia coli by the polymerase chain reaction and restriction fragment length polymorphism analysis
1991
Infection by verocytotoxin-producing Escherichia coli
1989
Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion
1996
OB(oligonucleotide/oligosaccharide binding)-fold: common structural and functional solution for non-homologous sequences.
1993
Inorganic polyphosphate is needed for swimming, swarming, and twitching motilities of Pseudomonas aeruginosa
2000 Standout
Chemical Glycobiology
2001 StandoutScienceNobel
Comparative toxicity and virulence of Escherichia coli clones expressing variant and chimeric Shiga-like toxin type II operons
1995
Clinical Escherichia coli Strains Carrying stx Genes: stx Variants and stx -Positive Virulence Profiles
2002
Structure of Staphylococcal α-Hemolysin, a Heptameric Transmembrane Pore
1996 StandoutScience
Polymerase chain reaction for diagnosis of enterohemorrhagic Escherichia coli infection and hemolytic-uremic syndrome
1992
Toll-like receptor 4 polymorphisms are associated with resistance to Legionnaires' disease
2005 StandoutNobel
Identification and Functional Characterization of Chicken Toll-Like Receptor 5 Reveals a Fundamental Role in the Biology of Infection with Salmonella enterica Serovar Typhimurium
2005
Investigation of ribosome binding by the Shiga toxin A1 subunit, using competition and site-directed mutagenesis
1997
Identification of the Shiga toxin A-subunit residues required for holotoxin assembly
1993
Acute renal tubular necrosis and death of mice orally infected with Escherichia coli strains that produce Shiga-like toxin type II
1990
Cloning and Sequencing of Two New Verotoxin 2 Variant Genes of Escherichia coli Isolated from Cases of Human and Bovine Diarrhea
1993
Differentiation of Genes Coding for Escherichia coli Verotoxin 2 and the Verotoxin Associated with Porcine Edema Disease (VTe) by the Polymerase Chain Reaction
1990
Exogenous cytokine modulation or neutralization of interleukin‐10 enhance survival in lipopolysaccharide‐hyporesponsive C3H/HeJ mice with Klebsiella infection
1999
Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
2003
Potent Immunoregulatory Effects ofSalmonella typhiFlagella on Antigenic Stimulation of Human Peripheral Blood Mononuclear Cells
1999
Rapid and sensitive method for detection of Shiga-like toxin-producing Escherichia coli in ground beef using the polymerase chain reaction
1992
Virulence of enterohemorrhagic Escherichia coli O91:H21 clinical isolates in an orally infected mouse model
1993
Isolation and characterization of monoclonal antibodies to Shiga-like toxin II of enterohemorrhagic Escherichia coli and use of the monoclonal antibodies in a colony enzyme-linked immunosorbent assay
1988
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Virulence markers of Shiga-like toxin-producing Escherichia coli strains originating from healthy domestic animals of different species
1995
Solution Structure of Prokaryotic Ribosomal Protein S17 by High-Resolution NMR Spectroscopy
1996 StandoutNobel
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Role of Microglia in Central Nervous System Infections
2004
Common themes in microbial pathogenicity
1989
Identification, Characterization, and Distribution of a Shiga Toxin 1 Gene Variant ( stx 1c ) in Escherichia coli Strains Isolated from Humans
2002
Toll-Like Receptor 4 Expression Is Required to Control ChronicMycobacterium tuberculosisInfection in Mice
2002
Mouse genetic locus Lps influences susceptibility to Neisseria meningitidis infection
1988
Effect of Shiga toxin and Shiga-like toxins on eukaryotic cells
2001
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Single primer pair for amplifying segments of distinct Shiga-like-toxin genes by polymerase chain reaction
1989
Detection of Shiga toxin-producing Shigella dysenteriae type 1 and Escherichia coli by using polymerase chain reaction with incorporation of digoxigenin-11-dUTP
1991
The pathogenic mechanisms of Shiga toxin and the Shiga‐like toxins
1991
Invasion by Salmonella typhimurium is affected by the direction of flagellar rotation
1992
Lipopolysaccharide or Whole Bacteria Block the Conversion of Inflammatory Monocytes into Dendritic Cells In Vivo
2003 StandoutNobel
The specific activities of Shiga-like toxin type II (SLT-II) and SLT-II-related toxins of enterohemorrhagic Escherichia coli differ when measured by Vero cell cytotoxicity but not by mouse lethality
1994
A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease
2003 StandoutNobel
Direct detection of Escherichia coli Shiga-like toxin genes in primary fecal cultures by polymerase chain reaction
1993
Comparison of the relative toxicities of Shiga-like toxins type I and type II for mice
1993
Roles of a ribosome-binding site and mRNA secondary structure in differential expression of Shiga toxin genes
1993
Shiga-like toxin II-related cytotoxins in Citrobacter freundii strains from humans and beef samples
1993
Antibody Therapy in the Management of Shiga Toxin-Induced Hemolytic Uremic Syndrome
2004
Structure and function of cholera toxin and the related Escherichia coli heat-labile enterotoxin
1992
Bacterial toxins
1992
A reporter transgene indicates renal-specific induction of tumor necrosis factor (TNF) by shiga-like toxin. Possible involvement of TNF in hemolytic uremic syndrome.
1993 StandoutNobel
THE ANTI-SIGMA FACTORS
1998
Regulation of the Shiga-like toxin II operon in Escherichia coli
1996
GENETIC ANALYSIS OF HOST RESISTANCE: Toll-Like Receptor Signaling and Immunity at Large
2006 StandoutNobel
Characterization of F107 fimbriae of Escherichia coli 107/86, which causes edema disease in pigs, and nucleotide sequence of the F107 major fimbrial subunit gene, fedA
1992
Escherichia coli O157:H7 in microbial flora of sheep
1996
RAGE and amyloid-β peptide neurotoxicity in Alzheimer's disease
1996 StandoutNature
Detection of Various Variant Verotoxin Genes in Escherichia coli by Polymerase Chain Reaction
1993
An enzyme-linked immunosorbent assay-based isolation procedure for verotoxigenic Escherichia coli
1993
Alteration of the carbohydrate binding specificity of verotoxins from Gal alpha 1-4Gal to GalNAc beta 1-3Gal alpha 1-4Gal and vice versa by site-directed mutagenesis of the binding subunit.
1992
Frequent loss of Shiga-like toxin genes in clinical isolates of Escherichia coli upon subcultivation
1992
Functions of Cell Surface Heparan Sulfate Proteoglycans
1999 Standout
Analysis of Shiga toxin subunit association by using hybrid A polypeptides and site-specific mutagenesis
1995
Shiga Toxin, Shiga-like Toxin II Variant, and Ricin Are All Single-site RNA N-Glycosidases of 28 S RNA When Microinjected into Xenopus Oocytes
1989
Pathogenesis and Diagnosis of Shiga Toxin-Producing Escherichia coli Infections
1998 Standout
Flagella and Chemotaxis Are Required for Efficient Induction ofSalmonella entericaSerovar Typhimurium Colitis in Streptomycin-Pretreated Mice
2004
Structure-function analyses of Shiga toxin and the Shiga-like toxins
1990
Evaluation of oligonucleotide probes for identification of shiga-like-toxin-producing Escherichia coli
1989
Caenorhabditis elegans responses to bacteria from its natural habitats
2016 StandoutNobel
Co‐ordination of pathogenicity island expression by the BipA GTPase in enteropathogenic Escherichia coli (EPEC)
2003
Physiology of Microglia
2011 Standout
Works of D L Weinstein being referenced
Herpes simplex virus type I infection of the CNS induces major histocompatibility complex antigen expression on rat microglia
1990
Functional analysis of the Shiga toxin and Shiga-like toxin type II variant binding subunits by using site-directed mutagenesis
1990
Salmonella typhi stimulation of human intestinal epithelial cells induces secretion of epithelial cell-derived interleukin-6
1997
Flagellar Phase Variation ofSalmonella entericaSerovar Typhimurium Contributes to Virulence in the Murine Typhoid Infection Model but Does Not InfluenceSalmonella-Induced Enteropathogenesis
2001
A Salmonella typhimurium virulence gene linked to flg
1989
Flagella help Salmonella typhimurium survive within murine macrophages
1984
Macrophage defect and inflammatory cell recruitment dysfunction in Salmonella susceptible C3H/HeJ mice
1986
Cloning and sequencing of a Shiga-like toxin type II variant from Escherichia coli strain responsible for edema disease of swine
1988
Effects of iron and temperature on Shiga-like toxin I production by Escherichia coli
1988
Mouse chromosome 1 Ity locus regulates microbicidal activity of isolated peritoneal macrophages against a diverse group of intracellular and extracellular bacteria.
1985
In vivo formation of hybrid toxins comprising Shiga toxin and the Shiga-like toxins and role of the B subunit in localization and cytotoxic activity
1989
Flagella of Salmonella typhimurium are a virulence factor in infected C57BL/6J mice
1984
Genetics of type IIa heat-labile enterotoxin of Escherichia coli: operon fusions, nucleotide sequence, and hybridization studies
1987
Absence of All Components of the Flagellar Export and Synthesis Machinery Differentially Alters Virulence ofSalmonella entericaSerovar Typhimurium in Models of Typhoid Fever, Survival in Macrophages, Tissue Culture Invasiveness, and Calf Enterocolitis
2001