Standout Papers
Citation Impact
Citing Papers
Multidimensional traction force microscopy reveals out-of-plane rotational moments about focal adhesions
2012 StandoutNobel
Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
2012
Actin retrograde flow actively aligns and orients ligand-engaged integrins in focal adhesions
2017 StandoutNobel
Gr-1+CD11b+ Myeloid Cells Tip the Balance of Immune Protection to Tumor Promotion in the Premetastatic Lung
2010
Bone Marrow–Derived Gr1+ Cells Can Generate a Metastasis-Resistant Microenvironment Via Induced Secretion of Thrombospondin-1
2013
Inflammation Triggers Zeb1-Dependent Escape from Tumor Latency
2016
Neutrophils Suppress Intraluminal NK Cell–Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells
2016
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
TGF-β Signaling in Myeloid Cells Is Required for Tumor Metastasis
2013
Metastasis: from dissemination to organ-specific colonization
2009 Standout
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Hypoxic control of metastasis
2016 Science
Cancer and Altered Metabolism: Potential Importance of Hypoxia-Inducible Factor and 2-Oxoglutarate-Dependent Dioxygenases
2011 StandoutNobel
Molecular mechanisms mediating metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Cancer–stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis
2012 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Hypoxia-Inducible Factors and the Response to Hypoxic Stress
2010 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Role of Carcinoma-Associated Fibroblasts and Hypoxia in Tumor Progression
2010
Tumor Exosomal RNAs Promote Lung Pre-metastatic Niche Formation by Activating Alveolar Epithelial TLR3 to Recruit Neutrophils
2016
Neutrophils support lung colonization of metastasis-initiating breast cancer cells
2015 Nature
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
Dynamic interplay between the collagen scaffold and tumor evolution
2010
COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion
2010
VEGFR1 Activity Modulates Myeloid Cell Infiltration in Growing Lung Metastases but Is Not Required for Spontaneous Metastasis Formation
2009
Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients
2013
Macrophages, innate immunity and cancer: balance, tolerance, and diversity
2010
Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
2012 StandoutNatureNobel
Unravelling the complexity of metastasis — molecular understanding and targeted therapies
2011
Metastatic Stem Cells: Sources, Niches, and Vital Pathways
2014
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
2016 StandoutNobel
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
2012 StandoutNobel
IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
2015 Nature
Hallmarks of cancer: Interactions with the tumor stroma
2010
Regulation of angiogenesis: apoptotic cues from the ECM
2008
Macrophage Diversity Enhances Tumor Progression and Metastasis
2010 Standout
Tumor metastasis: moving new biological insights into the clinic
2013
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
The rationale for targeting the LOX family in cancer
2012
The hypoxic tumor microenvironment: A driving force for breast cancer progression
2015 StandoutNobel
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Molecular Mechanisms of Stress-Responsive Changes in Collagen and Elastin Networks in Skin
2016 Standout
The secreted factors responsible for pre-metastatic niche formation: Old sayings and new thoughts
2011
Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine
2016 StandoutNobel
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Mechanisms Governing Metastatic Dormancy and Reactivation
2013
Remodelling the extracellular matrix in development and disease
2014 Standout
Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis
2019 StandoutNobel
Emerging Biological Principles of Metastasis
2017 Standout
Current and emerging concepts in tumour metastasis
2010
Hypoxia: Signaling the Metastatic Cascade
2016
Rho signaling and mechanical control of vascular development
2008
Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
2013
The metastatic niche: adapting the foreign soil
2009
Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer
2013
Microenvironmental regulation of metastasis
2008 Standout
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
Neutrophils in cancer: neutral no more
2016 Standout
Defining the Anthropocene
2015 StandoutNature
Immune cell promotion of metastasis
2015
The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis
2014
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Tumors as Organs: Complex Tissues that Interface with the Entire Organism
2010
Tumor Entrained Neutrophils Inhibit Seeding in the Premetastatic Lung
2011
Extracellular matrix: A gatekeeper in the transition from dormancy to metastatic growth
2010
Emerging targeted agents in metastatic breast cancer
2013
Tumor-Host Interactions: A Far-Reaching Relationship
2010
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Platelet factor 4 is produced by subsets of myeloid cells in premetastatic lung and inhibits tumor metastasis
2016
Myeloid-derived suppressor cells in the tumor microenvironment: expect the unexpected
2015
Balancing forces: architectural control of mechanotransduction
2011
Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation
2011
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy
2012
Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression
2014 StandoutNobel
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation
2011 StandoutNobel
Role of Hypoxia-Inducible Factors in Breast Cancer Metastasis
2013 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Oxygen Sensing, Hypoxia-Inducible Factors, and Disease Pathophysiology
2013 StandoutNobel
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Piezo1, a mechanically activated ion channel, is required for vascular development in mice
2014 StandoutNobel
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Molecular Pathways: Connecting Fibrosis and Solid Tumor Metastasis
2014
Validation of Lysyl Oxidase As a Prognostic Marker for Metastasis and Survival in Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Trial 90-03
2009
The Initial Hours of Metastasis: The Importance of Cooperative Host–Tumor Cell Interactions during Hematogenous Dissemination
2012
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Hypoxic retinal Müller cells promote vascular permeability by HIF-1–dependent up-regulation of angiopoietin-like 4
2013 StandoutNobel
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
2011 Standout
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Used planet: A global history
2013
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
The lack of type I interferon induces neutrophil-mediated pre-metastatic niche formation in the mouse lung
2015
Holocene carbon emissions as a result of anthropogenic land cover change
2010
Hypoxia-inducible factor 1 transcriptional activity in endothelial cells is required for acute phase cardioprotection induced by ischemic preconditioning
2012 StandoutNobel
Works of D. K. Bird being referenced
LOX-Mediated Collagen Crosslinking Is Responsible for Fibrosis-Enhanced Metastasis
2013
LOXL2-Mediated Matrix Remodeling in Metastasis and Mammary Gland Involution
2011
ERK-MAPK signaling opposes Rho-kinase to promote endothelial cell survival and sprouting during angiogenesis
2006
Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
2009 Standout
Lysyl oxidase enzymatic function increases stiffness to drive colorectal cancer progression through FAK
2012
The Role of Lysyl Oxidase in SRC-Dependent Proliferation and Metastasis of Colorectal Cancer
2011
Neotropical human–landscape interactions, fire, and atmospheric CO2during European conquest
2011