Citation Impact
Citing Papers
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Structure of the Histone Acetyltransferase Hat1
1998 StandoutNobel
A short linear peptide that folds into a native stable β-hairpin in aqueous solution
1994
S. cerevisiae α pheromone receptors activate a novel signal transduction pathway for mating partner discrimination
1991 StandoutNobel
Heteromultimeric channels formed by rat brain potassium-channel proteins
1990 StandoutNatureNobel
Model for signal sequence recognition from amino-acid sequence of 54K subunit of signal recognition particle
1989 StandoutNatureNobel
Kinetic analysis of folding and unfolding the 56 amino acid IgG-binding domain of streptococcal protein G
1992
The AID enzyme induces class switch recombination in fibroblasts
2002 StandoutNatureNobel
Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments
1991 StandoutNobel
Topogenic signals in integral membrane proteins
1988
Large increases in general stability for subtilisin BPN' through incremental changes in the free energy of unfolding
1989
Aromatic rescue of glycine in β sheets
1998
Germ-line transmission and expression of a human-derived yeast artificial chromosome
1993 Nature
Neuroligin 1: A splice site-specific ligand for β-neurexins
1995 StandoutNobel
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
The peptide repeat domain of nucleoporin Nup98 functions as a docking site in transport across the nuclear pore complex
1995 StandoutNobel
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
A novel potent vasoconstrictor peptide produced by vascular endothelial cells
1988 StandoutNature
p73 is a human p53-related protein that can induce apoptosis
1997 StandoutNatureNobel
A protein-folding reaction under kinetic control
1992 StandoutNatureNobel
Molecular analysis of the gene encoding α-lytic protease: evidence for a preproenzyme
1988
Single amino-acid changes in HIV envelope affect viral tropism and receptor binding
1989 StandoutNatureNobel
The αlytic protease pro-region does not require a physical linkage to activate the protease domain in vivo
1989 Nature
Measurement of the β-sheet-forming propensities of amino acids
1994 Nature
mec-3, a homeobox-containing gene that specifies differentiation of the touch receptor neurons in C. elegans
1988 StandoutNobel
Partial phenotypic correction of human Lesch-Nyhan (hypoxanthine-guanine phosphoribosyltransferase-deficient) lymphoblasts with a transmissible retroviral vector.
1984
Manipulation of T cell costimulatory and inhibitory signals for immunotherapy of prostate cancer
1997 StandoutNobel
Proteases of enhanced stability: Characteization of a thermostable variant of subtilisin
1986
A transmissible retrovirus expressing human hypoxanthine phosphoribosyltransferase (HPRT): gene transfer into cells obtained from humans deficient in HPRT.
1983
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
The nucleotide sequence and the tissue-specific expression of Drosophila c-src
1985 StandoutNobel
Protein folding kinetics exhibit an Arrhenius temperature dependence when corrected for the temperature dependence of protein stability
1997 StandoutNobel
Molecular cloning and characterization of a Ca2+/calmodulin-insensitive adenylyl cyclase from rat brain.
1991 StandoutNobel
An appraisal of the application of recombinant DNA techniques to chromosome defects
1985
Structure, expression, and mutation of the hypoxanthine phosphoribosyltransferase gene.
1984
MECHANISMS OF X-CHROMOSOME REGULATION
1988
Cotransformation and Gene Targeting in Mouse Embryonic Stem Cells
1991 StandoutNobel
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
Isolation of the proto-oncogene c-myb from D. melanogaster
1985 StandoutNobel
Plasmids for the cloning and expresion of full-length double-stranded cDNAs under control of the SV40 early or late gene promoter
1983
Analysis of prepro-alpha-lytic protease expression in Escherichia coli reveals that the pro region is required for activity
1989
A new cell division operon inEscherichia coli
1986
A homeobox-containing marker of posterior neural differentiation shows the importance of predetermination in neural induction
1987 StandoutNobel
Nucleotide sequence of the human N-myc gene.
1986 StandoutNobel
High-efficiency transformation of mammalian cells by plasmid DNA.
1987 Standout
A nerve growth factor-regulated messenger RNA encodes a new intermediate filament protein.
1988
A Family of AMPA-Selective Glutamate Receptors
1990 StandoutScienceNobel
Directed evolution of a thermostable esterase
1998 StandoutNobel
Expression of v-src and chicken c-src in rat cells demonstrates qualitative differences between pp60v-src and pp60c-src
1984 StandoutNobel
Nucleotide sequence and organization of the mouse adenine phosphoribosyltransferase gene: presence of a coding region common to animal and bacterial phosphoribosyltransferases that has a variable intron/exon arrangement.
1985
Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia
1985 StandoutScienceNobel
c-Ha-ras-1 proto-oncogene amplification and overexpression during the limited replicative life span of normal human fibroblasts.
1985
Fine structure of the human hypoxanthine phosphoribosyltransferase gene.
1986
c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene
1984
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
1986 StandoutNatureNobel
The SPA2 gene of Saccharomyces cerevisiae is important for pheromone-induced morphogenesis and efficient mating.
1990
A potential animal model for Lesch–Nyhan syndrome through introduction of HPRT mutations into mice
1987 StandoutNatureNobel
In vitro synthesized bacterial outer membrane protein is integrated into bacterial inner membranes but translocated across microsomal membranes
1986 StandoutNatureNobel
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
HPRT and the Lesch—Nyhan syndrome
1985
Dominant Positive and Negative Selection Using a Hygromycin Phosphotransferase-Thymidine Kinase Fusion Gene
1991
Spatial restriction in expression of a mouse homoeo box locus within the central nervous system
1986 Nature
Molecular Cloning of Complementary DNA for the Alpha Subunit of the G Protein that Stimulates Adenylate Cyclase
1985 StandoutScienceNobel
Infectious Sindbis virus transient expression vectors for studying antigen processing and presentation.
1992 StandoutNobel
Cotransformation and gene targeting in mouse embryonic stem cells.
1991 StandoutNobel
HPRT: GENE STRUCTURE, EXPRESSION, AND MUTATION
1985
Tuning the activity of an enzyme for unusual environments: sequential random mutagenesis of subtilisin E for catalysis in dimethylformamide.
1993 StandoutNobel
Molecular analysis of spontaneous hypoxanthine phosphoribosyltransferase mutations in thioguanine-resistant HL-60 human leukemia cells.
1989
Coupled prediction of protein secondary and tertiary structure
2003 StandoutNobel
Export and secretion of proteins by bacteria
1985
HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions
1984 StandoutNobel
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
cDNA isolated from a human T-cell library encodes a member of the protein-tyrosine-phosphatase family.
1989 StandoutNobel
A family of unusually spliced biologically active transcripts encoded by a Drosophila clock gene
1987 StandoutNatureNobel
YACs to the rescue
1993 StandoutNatureNobel
A new way of enhancing the thermostability of proteases
1986 Nature
Localized mutagenesis and evidence for post-transcriptional regulation of MAK3. A putative N-acetyltransferase required for double-stranded RNA virus propagation in Saccharomyces cerevisiae.
1992
Insertion of DNA sequences into the human chromosomal β-globin locus by homologous recombination
1985 StandoutNatureNobel
Nerve growth factor increases mRNA levels for the prion protein and the beta-amyloid protein precursor in developing hamster brain.
1988 StandoutNobel
Targeted mutation of the Hprt gene in mouse embryonic stem cells.
1988 StandoutNobel
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs
1984 Standout
Fine Structure of the Human Hypoxanthine Phosphoribosyltransferase Gene
1986
Works of D Filpula being referenced
Isolation and characterization of a full-length expressible cDNA for human hypoxanthine phosphoribosyl transferase.
1983
Gene for an immunoglobulin-binding protein from a group G streptococcus
1986
Isolation and Characterization of a Full-Length Expressible cDNA for Human Hypoxanthine Phosphoribosyltransferase
1983 Nobel
Genes for alkaline protease and neutral protease from Bacillus amyloliquefaciens contain a large open reading frame between the regions coding for signal sequence and mature protein
1984
Cloning and sequencing of a gene encoding an aminoglycoside 6'-N-acetyltransferase from an R factor of Citrobacter diversus
1988
Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene.
1985